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Molecular BioSystems

A new high quality chemical biology journal with a particular focus on the interface between chemistry and the -omic sciences and systems biology.

Hot Articles


Understanding apoptosis by systems biology approaches
Inna N. Lavrik, Roland Eils, Nicolai Fricker, Carina Pforr and Peter H. Krammer, Mol. BioSyst., 2009, 5, 1105
DOI: 10.1039/b905129p


Receptor tyrosine kinase signaling: a view from quantitative proteomics
Joern Dengjel, Irina Kratchmarova and Blagoy Blagoev, Mol. BioSyst., 2009, 5, 1112
DOI: 10.1039/b909534a


Antibacterial activity and cytotoxicity of PEGylated poly(amidoamine) dendrimers
Analette I. Lopez, Rose Y. Reins, Alison M. McDermott, Barbara W. Trautner and Chengzhi Cai, Mol. BioSyst., 2009, 5, 1148
DOI: 10.1039/b904746h


The repertoire of glycan determinants in the human glycome
Richard D. Cummings, Mol. BioSyst., 2009, 5, 1087
DOI: 10.1039/b907931a


Metabolic profiling of Helicobacter pylori glycosylation
Maria B. Koenigs, Elizabeth A. Richardson and Danielle H. Dube, Mol. BioSyst., 2009, 5, 909
DOI: 10.1039/b902178g


Probing phosphorylation by non-mammalian isoprenoid biosynthetic enzymes using 1H–31P–31P correlation NMR spectroscopy
Ananya Majumdar, Meha H. Shah, J. Kipchirchir Bitok, Maria E. Hassis-LeBeau and Caren L. Freel Meyers, Mol. BioSyst., 2009, 5, 935
DOI: 10.1039/b903513c


Design, synthesis and biological evaluation of sugar-derived esters, -ketoesters and -ketoamides as inhibitors for Mycobacterium tuberculosis antigen 85C
Aditya K. Sanki, Julie Boucau, Francis E. Umesiri, Donald R. Ronning and Steven J. Sucheck, Mol. BioSyst., 2009, 5, 945
DOI: 10.1039/b902284h


Role of a salt bridge in the model protein crambin explored by chemical protein synthesis: X-ray structure of a unique protein analogue, [V15A]crambin--carboxamide
Duhee Bang, Valentina Tereshko, Anthony A. Kossiakoff and Stephen B. H. Kent, Mol. BioSyst., 2009, 5, 750
DOI: 10.1039/b903610e


Probing phosphorylation by non-mammalian isoprenoid biosynthetic enzymes using 1H–31P–31P correlation NMR spectroscopy
Ananya Majumdar, Meha H. Shah, J. Kipchirchir Bitok, Maria E. Hassis-LeBeau and Caren L. Freel Meyers, Mol. BioSyst., 2009, 5, 935
DOI: 10.1039/b903513c


Biocomputers: from test tubes to live cells
Yaakov Benenson, Mol. BioSyst., 2009, 5, 675
DOI: 10.1039/b902484k


Darwinian chemistry: towards the synthesis of a simple cell
David Loakes and Philipp Holliger, Mol. BioSyst., 2009, 5, 686
DOI: 10.1039/b904024b


Role of a salt bridge in the model protein crambin explored by chemical protein synthesis: X-ray structure of a unique protein analogue, [V15A]crambin--carboxamide
Duhee Bang, Valentina Tereshko, Anthony A. Kossiakoff and Stephen B. H. Kent, Mol. BioSyst., 2009, 5, 750
DOI: 10.1039/b903610e


How chromatin remodelling allows shuffling of immunoglobulin heavy chain genes
Adam J. Bowen and Anne E. Corcoran, Mol. BioSyst., 2008, 4, 790
DOI: 10.1039/b719771n


Combination dual responsive polypeptide vectors for enhanced gene delivery
Rujikan Nasanit, Parvez Iqbal, Mahmoud Soliman, Neil Spencer, Stephanie Allen, Martyn C. Davies, Simon S. Briggs, Leonard W. Seymour, Jon A. Preece and Cameron Alexander, Mol. BioSyst., 2008, 4, 741
DOI: 10.1039/b803262a


Photocrosslinkers illuminate interactions in living cells
Yoshihito Tanaka, Michelle R. Bond and Jennifer J. Kohler, Mol. BioSyst., 2008, 4, 473
DOI: 10.1039/b803218a


Enabling methodology for the end functionalisation of glycosaminoglycan oligosaccharides
Emiliano Gemma, Odile Meyer, Duan Uhrín and Alison N. Hulme, Mol. BioSyst., 2008, 4, 481
DOI: 10.1039/b801666f


Re-engineering a split-GFP reassembly screen to examine RING-domain interactions between BARD1 and BRCA1 mutants observed in cancer patients
Mohosin Sarkar and Thomas J. Magliery, Mol. BioSyst., 2008, 4, 599
DOI: 10.1039/b802481b


Prediction of cardiac transcription networks based on molecular data and complex clinical phenotypes
Martje Toenjes, Markus Schueler, Stefanie Hammer, Utz J. Pape, Jenny J. Fischer, Felix Berger, Martin Vingron and Silke Sperling, Mol. BioSyst., 2008, 4, 589
DOI: 10.1039/b800207j


Visualizing the spatial distribution of secondary metabolites produced by marine cyanobacteria and sponges via MALDI-TOF imaging
Eduardo Esquenazi, Cameron Coates, Luke Simmons, David Gonzalez, William H. Gerwick and Pieter C. Dorrestein, Mol. BioSyst., 2008, 4, 562
DOI: 10.1039/b720018h


A chemical approach for detecting sulfenic acid-modified proteins in living cells
Khalilah G. Reddie, Young Ho Seo, Wilson B. Muse III, Stephen E. Leonard and Kate S. Carroll, Mol. BioSyst., 2008, 4, 521
DOI: 10.1039/b719986d


Conformation and the sodium ion condensation on DNA and RNA structures in the presence of a neutral cosolute as a mimic of the intracellular media
Shu-ichi Nakano, Lei Wu, Hirohito Oka, Hisae Tateishi Karimata, Toshimasa Kirihata, Yuichi Sato, Satoshi Fujii, Hiroshi Sakai, Masayuki Kuwahara, Hiroaki Sawai and Naoki Sugimoto, Mol. BioSyst., 2008, 4, 579
DOI: 10.1039/b718806d


Direct printing of trichlorosilanes on glass for selective protein adsorption and cell growth
Dawn M. Yanker and Joshua A. Maurer, Mol. BioSyst., 2008, 4, 502
DOI: 10.1039/b801161c


Visualization of phosphatase activity in living cells with a FRET-based calcineurin activity sensor
Robert H. Newman and Jin Zhang, Mol. BioSyst., 2008, 4, 496
DOI: 10.1039/b720034j


A primer on ankyrin repeat function in TRP channels and beyond
Rachelle Gaudet, Mol. BioSyst., 2008, 4, 372
DOI: 10.1039/b801481g


The genome BLASTatlas—a GeneWiz extension for visualization of whole-genome homology
Peter F. Hallin, Tim T. Binnewies and David W. Ussery, Mol. BioSyst., 2008, 4, 363
DOI: 10.1039/b717118h


The importance of surfaces in single-molecule bioscience
Mari-Liis Visnapuu, Daniel Duzdevich and Eric C. Greene, Mol. BioSyst., 2008, 4, 394
DOI: 10.1039/b800444g


Choose your own path: specificity in Ras GTPase signaling
Lawrence E. Goldfinger, Mol. BioSyst., 2008, 4, 293
DOI: 10.1039/b716887j


Gene regulation technologies in zebrafish
Hanife Esengil and James K. Chen, Mol. BioSyst., 2008, 4, 300
DOI: 10.1039/b718447f


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