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Paper

Org. Biomol. Chem., 2005, 3, 3184 - 3187, DOI: 10.1039/b507028g

A straightforward approach towards thiazoles and endothiopeptides via Ugi reaction

Uli Kazmaier and Stefanie Ackermann

Endothiopeptides can easily be obtained via Ugi reaction using thio acids as acid components. If isonitriles with an acetal group are applied, the endothiopeptides can directly be converted into thiazoles using TMSCl–NaI under microwave irradiation.

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