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Paper

Org. Biomol. Chem., 2006, 4, 299 - 301, DOI: 10.1039/b512195g

Scandium triflate catalyzed cycloaddition of imines with 1,1-cyclopropanediesters: efficient and diastereoselective synthesis of multisubstituted pyrrolidines

Yan-Biao Kang, Yong Tang and Xiu-Li Sun

A tandem ring-opening–cyclization reaction of cyclopropanes with imines in the presence of 5 mol% of scandium triflate was developed for the highly diastereoselective synthesis of multisubstituted pyrrolidines.

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