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Organic & Biomolecular Chemistry

The international home of synthetic, physical and biomolecular organic chemistry.




Paper

Org. Biomol. Chem., 2006, 4, 1663 - 1666, DOI: 10.1039/b602536f


A facile and highly efficient route to -amino phosphonates via three-component reactions catalyzed by Mg(ClO4)2 or molecular iodine

Jie Wu, Wei Sun, Hong-Guang Xia and Xiaoyu Sun


Three-component reactions of aldehydes, amines, and diethyl phosphite catalyzed by Mg(ClO4)2 or molecular iodine afforded the corresponding -amino phosphonates in excellent yields under mild reaction conditions.

Graphical abstract image for this article  (ID: b602536f)