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Paper

Org. Biomol. Chem., 2009, 7, 4000 - 4008, DOI: 10.1039/b907787a

A new one-pot hydroformylation/Strecker synthesis as a versatile synthetic tool for polyfunctional compounds and functionalization of dendrimers

Muhammad Afzal Subhani, Kai-Sven Müller, Fikret Koç and Peter Eilbracht

A versatile and high yielding one-pot hydroformylation/Strecker synthesis is reported for the synthesis of various -aminonitriles. This methodology allows functionalization of dendrimers (e.g. polyamines 4–7) and hyper branched polymers (e.g. polyallyl glycerol 12) to give corresponding dendritic structures with -aminonitriles and/or amino acids in the outer shell in good to excellent yields.

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