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Article citation: Clémence Queffélec, Org. Biomol. Chem., 2010, DOI: 10.1039/b917428a
Facile P,N-heterocycle synthesis via tandem aminomethylation–cyclization of H-phosphinate building blocks
Clémence Queffélec and Jean-Luc Montchamp
Various heterocycles containing phosphorus and nitrogen are easily synthesized from readily available H-phosphinate building blocks. Aminomethylation of these H-phosphinates is followed by in situ cyclization through substitution or cross-coupling to produce novel heterocycles in moderate to good yields.
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