Communication

Org. Biomol. Chem., 2010, 8, 50 - 52, DOI: 10.1039/b919387a

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Small molecule induced control in duplex and triplex DNA-directed chemical reactions

Mikkel F. Jacobsen, Jens B. Ravnsbæk and Kurt V. Gothelf

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Triplex DNA binders can effectively control copper-catalysed alkyne–azide click reactions in DNA architecture, such that either duplex or triplex DNA directed reactions of terminally attached azides and alkynes occur, in the absence or presence of triplex DNA binder, respectively.

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