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Organic & Biomolecular Chemistry

The international home of synthetic, physical and biomolecular organic chemistry.



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Org. Biomol. Chem., 2010, 8, 533 - 535, DOI: 10.1039/b919526b

A short, chemoenzymatic route to chiral -aryl--amino acids using reductases from anaerobic bacteria

Anna Fryszkowska, Karl Fisher, John M. Gardiner and Gill M. Stephens

A short chemoenzymatic synthesis of -aryl--aminobutyric acids has been developed, based on a highly enantioselective biocatalytic reduction of -aryl--cyano-,-unsaturated carboxylic acids.

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