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Perkin Transactions 1 ceased publication in 2002. Organic & Biomolecular Chemistry is the RSC's journal for high-quality, original organic chemistry research.
Paper
J. Chem. Soc., Perkin Trans. 1, 2001, 358 - 361, DOI: 10.1039/b008814p
A polymer-supported thionating reagent
Steven V. Ley, Andrew G. Leach and R. Ian Storer
A new polymer-supported reagent for the conversion of carbonyls to thiocarbonyls has been developed and its use demonstrated on a range of amides. Secondary or tertiary amides are converted cleanly and efficiently through to the corresponding thioamides and primary amides are converted to the corresponding nitriles. The reactions can be facilitated by conventional heating. However, if microwave heating is used, in the presence of an ionic liquid, enhanced reaction rates are achieved.
