Issue 0, 1980

Synthesis of heterocyclic compounds via enamines. Part 8. Acid-catalysed transformations in 4,4,6-trimethyl-1,4-dihydropyrimidine-2(3H)-thione derivatives and related compounds

Abstract

1-Substituted 4,4,6-trimethyl-1,4-dihydropyrimidine-2(3H)-thiones (2) on heating in 11M-HCl at 100–110° are converted into the corresponding 2-substituted-amino-4,6,6-trimethyl-6H-1,3-thiazines (4) and/or thioureas. But at 95–100°, Dimroth rearrangement products, e.g, the corresponding 2-substituted-amino-4,4,6-trimethyl 4H-1,3-thiazines (3) are formed.

Article information

Article type
Paper

J. Chem. Soc., Perkin Trans. 1, 1980, 1013-1018

Synthesis of heterocyclic compounds via enamines. Part 8. Acid-catalysed transformations in 4,4,6-trimethyl-1,4-dihydropyrimidine-2(3H)-thione derivatives and related compounds

H. Singh and P. Singh, J. Chem. Soc., Perkin Trans. 1, 1980, 1013 DOI: 10.1039/P19800001013

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Spotlight

Advertisements