Chemical biology news and research from across RSC Publishing.
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Specific N-terminal protein labelling: use of FMDV 3Cpro protease and native chemical ligation
Gillian K. Busch, Edward W. Tate, Piers R. J. Gaffney, Erika Rosivatz, Rudiger Woscholski and Robin J. Leatherbarrow, Chem. Commun., 2008, 3369
DOI: 10.1039/b806727a
Dunking doughnuts into cells—selective cellular translocation and in vivo analysis of polymeric micro-doughnuts
Lois Alexander, Kevin Dhaliwal, John Simpson and Mark Bradley, Chem. Commun., 2008, 3507
DOI: 10.1039/b805323e
Toward the discovery of potent inhibitors of botulinum neurotoxin A: development of a robust LC MS based assay operational from low to subnanomolar enzyme concentrations
Kate
ina 
apková, Mark S. Hixon, Laura A. McAllister and Kim D. Janda, Chem. Commun., 2008, 3525
DOI: 10.1039/b808305c
Unfolding and melting of DNA (RNA) hairpins: the concept of structure-specific 2D dynamic landscapes
Milo M. Lin, Lars Meinhold, Dmitry Shorokhov and Ahmed H. Zewail, Phys. Chem. Chem. Phys., 2008, 10, 4227
DOI: 10.1039/b804675c
Solar water-splitting into H2 and O2: design principles of photosystem II and hydrogenases
Wolfgang Lubitz, Edward J. Reijerse and Johannes Messinger, Energy Environ. Sci., 2008, 1, 15
DOI: 10.1039/b808792j
Chemotaxis in microfluidic devices—a study of flow effects
Carsten Beta, Toni Fröhlich, Hendrik U. Bödeker and Eberhard Bodenschatz, Lab Chip, 2008, 8, 1087
DOI: 10.1039/b801331d
Nano-imaging of trace metals by synchrotron X-ray fluorescence into dopaminergic single cells and neurite-like processes
Asuncion Carmona, Peter Cloetens, Guillaume Devès, Sylvain Bohic and Richard Ortega, J. Anal. At. Spectrom., 2008, 23, 1083
DOI: 10.1039/b802242a
Micro X-ray fluorescence imaging and micro X-ray absorption spectroscopy of cadmium hyper-accumulating plant, Arabidopsis halleri ssp. gemmifera, using high-energy synchrotron radiation
Naoki Fukuda, Akiko Hokura, Nobuyuki Kitajima, Yasuko Terada, Hiroyuki Saito, Tomoko Abe and Izumi Nakai, J. Anal. At. Spectrom., 2008, 23, 1068
DOI: 10.1039/b803602k
Endothelial cell polarization and chemotaxis in a microfluidic device
Amir Shamloo, Ning Ma, Mu-ming Poo, Lydia L. Sohn and Sarah C. Heilshorn, Lab Chip, 2008, 8, 1292
DOI: 10.1039/b719788h
Photopolymerized diffusion-defined polyacrylamide gradient gels for on-chip protein sizing
Catherine T. Lo, Daniel J. Throckmorton, Anup K. Singh and Amy E. Herr, Lab Chip, 2008, 8, 1273
DOI: 10.1039/b804485f
Detecting bacteria and determining their susceptibility to antibiotics by stochastic confinement in nanoliter droplets using plug-based microfluidics
James Q. Boedicker, Liang Li, Timothy R. Kline and Rustem F. Ismagilov, Lab Chip, 2008, 8, 1265
DOI: 10.1039/b804911d
How chromatin remodelling allows shuffling of immunoglobulin heavy chain genes
Adam J. Bowen and Anne E. Corcoran, Mol. BioSyst., 2008, 4, 790
DOI: 10.1039/b719771n
Exploring the substrate specificity of OxyB, a phenol coupling P450 enzyme involved in vancomycin biosynthesis
Katharina Woithe, Nina Geib, Odile Meyer, Tanja Wörtz, Katja Zerbe and John A. Robinson, Org. Biomol. Chem., 2008, 6, 2861
DOI: 10.1039/b805956j
A combined SPS–LCD sensor for screening protease specificity
Louise S. Birchall, Rein V. Ulijn and Simon J. Webb, Chem. Commun., 2008, 2861
DOI: 10.1039/b805321a
Novel neutral imidazole-lipophosphoramides for transfection assays
Mathieu Mével, Cécile Neveu, Cristine Gonçalves, Jean-Jacques Yaouanc, Chantal Pichon, Paul-Alain Jaffrès and Patrick Midoux, Chem. Commun., 2008, 3124
DOI: 10.1039/b805226c
Chemotaxis in microfluidic devices—a study of flow effects
Carsten Beta, Toni Fröhlich, Hendrik U. Bödeker and Eberhard Bodenschatz, Lab Chip, 2008, 8, 1087
DOI: 10.1039/b801331d
Microfluidic add-on for standard electrophysiology chambers
Javeed Shaikh Mohammed, Hector Hugo Caicedo, Christopher P. Fall and David T. Eddington, Lab Chip, 2008, 8, 1048
DOI: 10.1039/b802037j
Living cantilever arrays
for characterization of mass of single live cells in fluids
Kidong Park, Jaesung Jang, Daniel Irimia, Jennifer Sturgis, James Lee, J. Paul Robinson, Mehmet Toner and Rashid Bashir, Lab Chip, 2008, 8, 1034
DOI: 10.1039/b803601b
Combination dual responsive polypeptide vectors for enhanced gene delivery
Rujikan Nasanit, Parvez Iqbal, Mahmoud Soliman, Neil Spencer, Stephanie Allen, Martyn C. Davies, Simon S. Briggs, Leonard W. Seymour, Jon A. Preece and Cameron Alexander, Mol. BioSyst., 2008, 4, 741
DOI: 10.1039/b803262a
