High-performance liquid chromatography-electrospray ionisation tandem mass spectrometry
Definition: A method where the sample mixture is first separated by high-performance liquid chromatography before being ionised by forcing a solution (usually in an organic solvent) of it through a small heated capillary (at a flow rate of 1--10 uL min1) into an electric field to produce a very fine mist of charged droplets. The ions are then characterised according to mass-to-charge ratio and relative abundance by two mass spectrometers in series.
ID: CMO:0000578
Synonyms:
More about the RSC Chemical Methods Ontology (CMO)
Articles referencing this term
Yasumitsu Ogra, Takashi Kitaguchi, Kazuya Ishiwata, Noriyuki Suzuki, Toshihiko Toida and Kazuo T. Suzuki, Metallomics, 2009
, 1
, 78
DOI: 10.1039/b813118j
J. Susanne Becker, Ryszard Lobinski and J. Sabine Becker, Metallomics, 2009
, 1
, 312
DOI: 10.1039/b822974k
Diego Esteban-Fernández, Estefanía Moreno-Gordaliza, Benito Cañas, María Antonia Palacios and María Milagros Gómez-Gómez, Metallomics, 2010
, 2
, 19
DOI: 10.1039/b911438f
Yuan-Na Li, Hai-Long Wu, Jin-Fang Nie, Shu-Fang Li, Yong-Jie Yu, Shu-Rong Zhang and Ru-Qin Yu, Anal. Methods, 2009
, 1
, 115
DOI: 10.1039/b9ay00048h