High-performance liquid chromatography-electrospray ionisation tandem mass spectrometry
Definition: A method where the sample mixture is first separated by high-performance liquid chromatography before being ionised by forcing a solution (usually in an organic solvent) of it through a small heated capillary (at a flow rate of 1--10 uL min1) into an electric field to produce a very fine mist of charged droplets. The ions are then characterised according to mass-to-charge ratio and relative abundance by two mass spectrometers in series.
Articles referencing this term
Yasumitsu Ogra, Takashi Kitaguchi, Kazuya Ishiwata, Noriyuki Suzuki, Toshihiko Toida and Kazuo T. Suzuki, Metallomics, 2009 , 1 , 78
J. Susanne Becker, Ryszard Lobinski and J. Sabine Becker, Metallomics, 2009 , 1 , 312
Diego Esteban-Fernández, Estefanía Moreno-Gordaliza, Benito Cañas, María Antonia Palacios and María Milagros Gómez-Gómez, Metallomics, 2010 , 2 , 19
Yuan-Na Li, Hai-Long Wu, Jin-Fang Nie, Shu-Fang Li, Yong-Jie Yu, Shu-Rong Zhang and Ru-Qin Yu, Anal. Methods, 2009 , 1 , 115