Sharpless asymmetric epoxidation

Definition: The epoxidation of an allylic alcohol to give a beta,gamma-epoxy alcohol, with control of absolute stereochemistry at the two new stereocentres. The oxidising agent is tert-butyl hydroperoxide, and the catalyst is a complex of titanium salt and optically active diethyl tartrate.

ID: RXNO:0000141

Synonyms:

More about the RSC Name Reaction Ontology (RXNO)

Articles referencing this term

Highly regioselective ring-opening of trisubstituted aziridines by sulfur-stabilised carbanions
Santiago Carballares, Donald Craig, Christopher J. T. Hyland, Pengfei Lu, Tanya Mathie and Andrew J. P. White, Chem. Commun., 2009 , 451
DOI: 10.1039/b815971h

Copper-catalyzed hydride transfer from LiAlH₄ for the formation of alkylidenecyclopropane derivatives
Samah Simaan and Ilan Marek, Chem. Commun., 2009 , 292
DOI: 10.1039/b817710d

Asymmetric synthesis of bis-tetrahydrofuran cores in annonaceous acetogenins
Chia-Hsiu Chen, Ting-Chun Kuan, Ke-Jhen Lu and Duen-Ren Hou, Org. Biomol. Chem., 2010 , 8 , 3624
DOI: 10.1039/c004672h