RSC - Lab Chip latest articles http://xlink.rsc.org/jumptojournal.cfm?journal_code=LC The Royal Society of Chemistry en-gb Copyright (c) 2010 The Royal Society of Chemistry Lab Chip Copyright (c) The Royal Society of Chemistry contracts-copyright@rsc.org 1473-01971473-0189The Royal Society of Chemistry The Royal Society of Chemistry Royal Society of Chemistry - Lab Chip latest articles RSC - Lab Chip latest articles http://www.rsc.org text/html text http://xlink.rsc.org/?DOI=b916126k&RSS=1 Five different flow distributors have been compared for their ability to distribute small sample volumes over the entire width of flat rectangular microfabricated pillar array columns.<p><img align="center" src="http://www.rsc.org/ejga/LC/2010/b916126k-ga.gif"/> </p>Joris Vangelooven, Wim De Malsche, Jeff Op De Beeck, Hamed Eghbali, Han Gardeniers, Gert Desmet <br/> (Paper from Lab Chip)<br/> Joris Vangelooven, Lab Chip, 2010, DOI: 10.1039/b916126k<br/> To cite this article before page numbers are assigned, use the DOI form of citation above. <br/>The content of this RSS Feed (c) The Royal Society of Chemistry Design and evaluation of flow distributors for microfabricated pillar array columns Joris Vangelooven Wim De Malsche Jeff Op De Beeck Hamed Eghbali Han Gardeniers Gert Desmet 10.1039/b916126k Lab Chip, 2010, DOI: 10.1039/b916126k html/pdf 2009-11-19 The Royal Society of Chemistry Copyright (c) 2010 The Royal Society of Chemistry DOI 10.1039/b916126k http://xlink.rsc.org/?DOI=b916669f&RSS=1 We present a perfusion chamber and a novel microfluidic probe with 6 apertures made of PDMS for local perfusion of organotypic brain slices with simultaneous confocal imaging.<p><img align="center" src="http://www.rsc.org/ejga/LC/2010/b916669f-ga.gif"/> </p>Arthur Queval, Nageswara R. Ghattamaneni, Cecile M. Perrault, Raminder Gill, Maryam Mirzaei, R. Anne McKinney, David Juncker <br/> (Paper from Lab Chip)<br/> Arthur Queval, Lab Chip, 2010, DOI: 10.1039/b916669f<br/> To cite this article before page numbers are assigned, use the DOI form of citation above. <br/>The content of this RSS Feed (c) The Royal Society of Chemistry Chamber and microfluidic probe for microperfusion of organotypic brain slices Arthur Queval Nageswara R. Ghattamaneni Cecile M. Perrault Raminder Gill Maryam Mirzaei R. Anne McKinney David Juncker 10.1039/b916669f Lab Chip, 2010, DOI: 10.1039/b916669f html/pdf 2009-11-19 The Royal Society of Chemistry Copyright (c) 2010 The Royal Society of Chemistry DOI 10.1039/b916669f http://xlink.rsc.org/?DOI=b913212k&RSS=1 Lithium-doped silicon nanowires (SiNW) have been used for sensitive detection of neutral lipids by laser-assisted desorption/ionization mass spectrometry (LDI-TOF/MS) for the first time. Those micro-fabricated SiNW chips should find wide application in food control and medicine.<p><img align="center" src="http://www.rsc.org/ejga/LC/2010/b913212k-ga.gif"/> </p>Alexander Muck, Thomas Stelzner, Uwe Hubner, Silke Christiansen, Ales Svatos <br/> (Paper from Lab Chip)<br/> Alexander Muck, Lab Chip, 2010, DOI: 10.1039/b913212k<br/> To cite this article before page numbers are assigned, use the DOI form of citation above. <br/>The content of this RSS Feed (c) The Royal Society of Chemistry Lithographically patterned silicon nanowire arrays for matrix free LDI-TOF/MS analysis of lipids Alexander Muck Thomas Stelzner Uwe Hubner Silke Christiansen Ales Svatos 10.1039/b913212k Lab Chip, 2010, DOI: 10.1039/b913212k html/pdf 2009-11-19 The Royal Society of Chemistry Copyright (c) 2010 The Royal Society of Chemistry DOI 10.1039/b913212k http://xlink.rsc.org/?DOI=b916746c&RSS=1 We demonstrate a chip with nanochannels with two segments of different heights. Nano-analytes become trapped when the channel dimensions shrink below the size of the particles.<p><img align="center" src="http://www.rsc.org/ejga/LC/2010/b916746c-ga.gif"/> </p>Mark N. Hamblin, Jie Xuan, Daniel Maynes, H. Dennis Tolley, David M. Belnap, Adam T. Woolley, Milton L. Lee, Aaron R. Hawkins <br/> (Paper from Lab Chip)<br/> Mark N. Hamblin, Lab Chip, 2010, DOI: 10.1039/b916746c<br/> To cite this article before page numbers are assigned, use the DOI form of citation above. <br/>The content of this RSS Feed (c) The Royal Society of Chemistry Selective trapping and concentration of nanoparticles and viruses in dual-height nanofluidic channels Mark N. Hamblin Jie Xuan Daniel Maynes H. Dennis Tolley David M. Belnap Adam T. Woolley Milton L. Lee Aaron R. Hawkins 10.1039/b916746c Lab Chip, 2010, DOI: 10.1039/b916746c html/pdf 2009-11-18 The Royal Society of Chemistry Copyright (c) 2010 The Royal Society of Chemistry DOI 10.1039/b916746c http://xlink.rsc.org/?DOI=b915047a&RSS=1 This paper demonstrates a method of optical path-length modulation for mirror-embedded microchannels that ensures imaging of in-focus side view as well as top view for three-dimensional particle measurement.<p><img align="center" src="http://www.rsc.org/ejga/LC/2010/b915047a-ga.gif"/> </p>Sungyoung Choi, Seung-Hoon Kim, Je-Kyun Park <br/> (Paper from Lab Chip)<br/> Sungyoung Choi, Lab Chip, 2010, DOI: 10.1039/b915047a<br/> To cite this article before page numbers are assigned, use the DOI form of citation above. <br/>The content of this RSS Feed (c) The Royal Society of Chemistry Optical path-length modulation for three-dimensional particle measurement in mirror-embedded microchannels Sungyoung Choi Seung-Hoon Kim Je-Kyun Park 10.1039/b915047a Lab Chip, 2010, DOI: 10.1039/b915047a html/pdf 2009-11-18 The Royal Society of Chemistry Copyright (c) 2010 The Royal Society of Chemistry DOI 10.1039/b915047a http://xlink.rsc.org/?DOI=b918167a&RSS=1 Generation of an alternating water-IL droplet chain, connected water-IL droplet pairs and separated water-IL droplet pairs at different flow rates of soybean oil.<p><img align="center" src="http://www.rsc.org/ejga/LC/2010/b918167a-ga.gif"/> </p>Xuan Feng, Ying Yi, Xu Yu, Dai-Wen Pang, Zhi-Ling Zhang <br/> (Paper from Lab Chip)<br/> Xuan Feng, Lab Chip, 2010, DOI: 10.1039/b918167a<br/> To cite this article before page numbers are assigned, use the DOI form of citation above. <br/>The content of this RSS Feed (c) The Royal Society of Chemistry Generation of water-ionic liquid droplet pairs in soybean oil on microfluidic chip Xuan Feng Ying Yi Xu Yu Dai-Wen Pang Zhi-Ling Zhang 10.1039/b918167a Lab Chip, 2010, DOI: 10.1039/b918167a html/pdf 2009-11-18 The Royal Society of Chemistry Copyright (c) 2010 The Royal Society of Chemistry DOI 10.1039/b918167a http://xlink.rsc.org/?DOI=b923816f&RSS=1 Petra Dittrich reviews the current literature in miniaturisation and related technologies.<p><img align="center" src="http://www.rsc.org/ejga/LC/2010/b923816f-ga.gif"/> </p> (Highlight from Lab Chip)<br/> Lab Chip, 2010, DOI: 10.1039/b923816f<br/> To cite this article before page numbers are assigned, use the DOI form of citation above. <br/>The content of this RSS Feed (c) The Royal Society of Chemistry Research Highlights RSC 10.1039/b923816f Lab Chip, 2010, DOI: 10.1039/b923816f html/pdf 2009-11-18 The Royal Society of Chemistry Copyright (c) 2010 The Royal Society of Chemistry DOI 10.1039/b923816f http://xlink.rsc.org/?DOI=b914874d&RSS=1 We present a microfluidic chip that is capable of generating complex patterns of shear flow, to study sensory and force transduction mechanisms in cells.<p><img align="center" src="http://www.rsc.org/ejga/LC/2010/b914874d-ga.gif"/> </p>Jianbin Wang, Jinseok Heo, Susan Z. Hua <br/> (Paper from Lab Chip)<br/> Jianbin Wang, Lab Chip, 2010, DOI: 10.1039/b914874d<br/> To cite this article before page numbers are assigned, use the DOI form of citation above. <br/>The content of this RSS Feed (c) The Royal Society of Chemistry Spatially resolved shear distribution in microfluidic chip for studying force transduction mechanisms in cells Jianbin Wang Jinseok Heo Susan Z. Hua 10.1039/b914874d Lab Chip, 2010, DOI: 10.1039/b914874d html/pdf 2009-11-17 The Royal Society of Chemistry Copyright (c) 2010 The Royal Society of Chemistry DOI 10.1039/b914874d http://xlink.rsc.org/?DOI=b917584a&RSS=1 A novel far-field nanoscopic velocimetry for nanotubes with high spatial resolution which is based on the STED and LIFPA techniques is presented.<p><img align="center" src="http://www.rsc.org/ejga/LC/2010/b917584a-ga.gif"/> </p>Cuifang Kuang, Guiren Wang <br/> (Paper from Lab Chip)<br/> Cuifang Kuang, Lab Chip, 2010, DOI: 10.1039/b917584a<br/> To cite this article before page numbers are assigned, use the DOI form of citation above. <br/>The content of this RSS Feed (c) The Royal Society of Chemistry A novel far-field nanoscopic velocimetry for nanofluidics Cuifang Kuang Guiren Wang 10.1039/b917584a Lab Chip, 2010, DOI: 10.1039/b917584a html/pdf 2009-11-17 The Royal Society of Chemistry Copyright (c) 2010 The Royal Society of Chemistry DOI 10.1039/b917584a http://xlink.rsc.org/?DOI=b913331c&RSS=1 We introduce a new type of connector for hard substrates (e.g. glass, silicon, and plastic) that employs two magnets to produce the sealing force. The connector is simple to fabricate, easy to assemble, low-cost and reusable.<p><img align="center" src="http://www.rsc.org/ejga/LC/2010/b913331c-ga.gif"/> </p>Javier Atencia, Gregory A. Cooksey, Andreas Jahn, Justin M. Zook, Wyatt N. Vreeland, Laurie E. Locascio <br/> (Technical Note from Lab Chip)<br/> Javier Atencia, Lab Chip, 2010, DOI: 10.1039/b913331c<br/> To cite this article before page numbers are assigned, use the DOI form of citation above. <br/>The content of this RSS Feed (c) The Royal Society of Chemistry Magnetic connectors for microfluidic applications Javier Atencia Gregory A. Cooksey Andreas Jahn Justin M. Zook Wyatt N. Vreeland Laurie E. Locascio 10.1039/b913331c Lab Chip, 2010, DOI: 10.1039/b913331c html/pdf 2009-11-16 The Royal Society of Chemistry Copyright (c) 2010 The Royal Society of Chemistry DOI 10.1039/b913331c http://xlink.rsc.org/?DOI=b914460a&RSS=1 A high-throughput screening platform to test for the mechanobiological response of cells to a range of uniform, equibiaxial, cyclic substrate deformations is described and applied to study activation of the canonical Wnt signaling pathway in mesenchymal stem cells.<p><img align="center" src="http://www.rsc.org/ejga/LC/2010/b914460a-ga.gif"/> </p>Christopher Moraes, Jan-Hung Chen, Yu Sun, Craig A. Simmons <br/> (Paper from Lab Chip)<br/> Christopher Moraes, Lab Chip, 2010, DOI: 10.1039/b914460a<br/> To cite this article before page numbers are assigned, use the DOI form of citation above. <br/>The content of this RSS Feed (c) The Royal Society of Chemistry Microfabricated arrays for high-throughput screening of cellular response to cyclic substrate deformation Christopher Moraes Jan-Hung Chen Yu Sun Craig A. Simmons 10.1039/b914460a Lab Chip, 2010, DOI: 10.1039/b914460a html/pdf 2009-11-16 The Royal Society of Chemistry Copyright (c) 2010 The Royal Society of Chemistry DOI 10.1039/b914460a http://xlink.rsc.org/?DOI=b917959c&RSS=1 Microfluidic devices are used for high-efficiency and high-purity capture of circulating tumor cells from peripheral whole blood samples of patients with castrate-resistant prostate cancer.<p><img align="center" src="http://www.rsc.org/ejga/LC/2010/b917959c-ga.gif"/> </p>Jason P. Gleghorn, Erica D. Pratt, Denise Denning, He Liu, Neil H. Bander, Scott T. Tagawa, David M. Nanus, Paraskevi A. Giannakakou, Brian J. Kirby <br/> (Communication from Lab Chip)<br/> Jason P. Gleghorn, Lab Chip, 2010, DOI: 10.1039/b917959c<br/> To cite this article before page numbers are assigned, use the DOI form of citation above. <br/>The content of this RSS Feed (c) The Royal Society of Chemistry Capture of circulating tumor cells from whole blood of prostate cancer patients using geometrically enhanced differential immunocapture (GEDI) and a prostate-specific antibody Jason P. Gleghorn Erica D. Pratt Denise Denning He Liu Neil H. Bander Scott T. Tagawa David M. Nanus Paraskevi A. Giannakakou Brian J. Kirby 10.1039/b917959c Lab Chip, 2010, DOI: 10.1039/b917959c html/pdf 2009-11-16 The Royal Society of Chemistry Copyright (c) 2010 The Royal Society of Chemistry DOI 10.1039/b917959c http://xlink.rsc.org/?DOI=b915750f&RSS=1 A feedback-based single particle trap embedded in a planar optofluidic chip is presented. It operates at optical power levels orders of magnitude lower than all-optical traps and enables simultaneous optical analysis of sub-micron trapped particles.<p><img align="center" src="http://www.rsc.org/ejga/LC/2010/b915750f-ga.gif"/> </p>S. Kuhn, B. S. Phillips, E. J. Lunt, A. R. Hawkins, H. Schmidt <br/> (Paper from Lab Chip)<br/> S. Kuhn, Lab Chip, 2010, DOI: 10.1039/b915750f<br/> To cite this article before page numbers are assigned, use the DOI form of citation above. <br/>The content of this RSS Feed (c) The Royal Society of Chemistry Ultralow power trapping and fluorescence detection of single particles on an optofluidic chip S. Kuhn B. S. Phillips E. J. Lunt A. R. Hawkins H. Schmidt 10.1039/b915750f Lab Chip, 2010, DOI: 10.1039/b915750f html/pdf 2009-11-16 The Royal Society of Chemistry Copyright (c) 2010 The Royal Society of Chemistry DOI 10.1039/b915750f http://xlink.rsc.org/?DOI=b909998k&RSS=1 We present the equations of motion for two-particle microactuators in fluid, which allow for precise characterization of the particles or of the fluid medium. The detailed understanding of the torque and rotation opens a wide range of possibilities in lab-on-a-chip applications.<p><img align="center" src="http://www.rsc.org/ejga/LC/2010/b909998k-ga.gif"/> </p>Andrea Ranzoni, Xander J. A. Janssen, Mikhail Ovsyanko, Leo J. van IJzendoorn, Menno W. J. Prins <br/> (Paper from Lab Chip)<br/> Andrea Ranzoni, Lab Chip, 2010, DOI: 10.1039/b909998k<br/> To cite this article before page numbers are assigned, use the DOI form of citation above. <br/>The content of this RSS Feed (c) The Royal Society of Chemistry Magnetically controlled rotation and torque of uniaxial microactuators for lab-on-a-chip applications Andrea Ranzoni Xander J. A. Janssen Mikhail Ovsyanko Leo J. van IJzendoorn Menno W. J. Prins 10.1039/b909998k Lab Chip, 2010, DOI: 10.1039/b909998k html/pdf 2009-11-16 The Royal Society of Chemistry Copyright (c) 2010 The Royal Society of Chemistry DOI 10.1039/b909998k http://xlink.rsc.org/?DOI=b904531g&RSS=1 A microfluidic device able to remove up to 97.58 +/- 0.45% of cells from plasma from a whole blood sample at a wide range of temperatures, using high flow rates and powered by hand.<p><img align="center" src="http://www.rsc.org/ejga/LC/2010/b904531g-ga.gif"/> </p>Angeles Ivon Rodriguez-Villarreal, Martin Arundell, Manuel Carmona, Josep Samitier <br/> (Paper from Lab Chip)<br/> Angeles Ivon Rodriguez-Villarreal, Lab Chip, 2010, DOI: 10.1039/b904531g<br/> To cite this article before page numbers are assigned, use the DOI form of citation above. <br/>The content of this RSS Feed (c) The Royal Society of Chemistry High flow rate microfluidic device for blood plasma separation using a range of temperatures Angeles Ivon Rodriguez-Villarreal Martin Arundell Manuel Carmona Josep Samitier 10.1039/b904531g Lab Chip, 2010, DOI: 10.1039/b904531g html/pdf 2009-11-13 The Royal Society of Chemistry Copyright (c) 2010 The Royal Society of Chemistry DOI 10.1039/b904531g http://xlink.rsc.org/?DOI=b917486a&RSS=1 Different developmental stages of Caenorhabditis elegans nematodes respond to specific ranges of electric field with different speeds. Application: drug discovery, sorting, and manipulation.<p><img align="center" src="http://www.rsc.org/ejga/LC/2010/b917486a-ga.gif"/> </p>Pouya Rezai, Asad Siddiqui, Ponnambalam Ravi Selvaganapathy, Bhagwati P. Gupta <br/> (Paper from Lab Chip)<br/> Pouya Rezai, Lab Chip, 2010, DOI: 10.1039/b917486a<br/> To cite this article before page numbers are assigned, use the DOI form of citation above. <br/>The content of this RSS Feed (c) The Royal Society of Chemistry Electrotaxis of Caenorhabditis elegans in a microfluidic environment Pouya Rezai Asad Siddiqui Ponnambalam Ravi Selvaganapathy Bhagwati P. Gupta 10.1039/b917486a Lab Chip, 2010, DOI: 10.1039/b917486a html/pdf 2009-11-13 The Royal Society of Chemistry Copyright (c) 2010 The Royal Society of Chemistry DOI 10.1039/b917486a http://xlink.rsc.org/?DOI=b914183a&RSS=1 We present the design, fabrication, and characterisation of an array of optical slot-waveguide ring resonator sensors, integrated with microfluidic sample handling in a compact cartridge, for multiplexed real-time label-free biosensing.<p><img align="center" src="http://www.rsc.org/ejga/LC/2010/b914183a-ga.gif"/> </p>C. F. Carlborg, K. B. Gylfason, A. Kazmierczak, F. Dortou, M. J. Banuls Polo, A. Maquieira Catala, G. M. Kresbach, H. Sohlstrom, T. Moh, L. Vivien, J. Popplewell, G. Ronan, C. A. Barrios, G. Stemme, W. van der Wijngaart <br/> (Paper from Lab Chip)<br/> C. F. Carlborg, Lab Chip, 2010, DOI: 10.1039/b914183a<br/> To cite this article before page numbers are assigned, use the DOI form of citation above. <br/>The content of this RSS Feed (c) The Royal Society of Chemistry A packaged optical slot-waveguide ring resonator sensor array for multiplex label-free assays in labs-on-chips C. F. Carlborg K. B. Gylfason A. Kazmierczak F. Dortou M. J. Banuls Polo A. Maquieira Catala G. M. Kresbach H. Sohlstrom T. Moh L. Vivien J. Popplewell G. Ronan C. A. Barrios G. Stemme W. van der Wijngaart 10.1039/b914183a Lab Chip, 2010, DOI: 10.1039/b914183a html/pdf 2009-11-12 The Royal Society of Chemistry Copyright (c) 2010 The Royal Society of Chemistry DOI 10.1039/b914183a http://xlink.rsc.org/?DOI=b915022f&RSS=1 This paper describes a palmtop-sized PCR system operated by the thermosiphon effect. The loop channel is molded in a polymer chip. Not only is the polymer chip advantageous for making disposable LOCs, but also has merits in versatile integration, mass production and facile handling.<p><img align="center" src="http://www.rsc.org/ejga/LC/2010/b915022f-ga.gif"/> </p>Kwang Hyo Chung, Se Ho Park, Yo Han Choi <br/> (Paper from Lab Chip)<br/> Kwang Hyo Chung, Lab Chip, 2010, DOI: 10.1039/b915022f<br/> To cite this article before page numbers are assigned, use the DOI form of citation above. <br/>The content of this RSS Feed (c) The Royal Society of Chemistry A palmtop PCR system with a disposable polymer chip operated by the thermosiphon effect Kwang Hyo Chung Se Ho Park Yo Han Choi 10.1039/b915022f Lab Chip, 2010, DOI: 10.1039/b915022f html/pdf 2009-11-12 The Royal Society of Chemistry Copyright (c) 2010 The Royal Society of Chemistry DOI 10.1039/b915022f http://xlink.rsc.org/?DOI=b917295e&RSS=1 PDMS and glass can be permanently bonded if exposed to a certain silane vapor. This inexpensive method does not require oxygen plasma or adhesives, and can be used by inexperienced operators.<p><img align="center" src="http://www.rsc.org/ejga/LC/2010/b917295e-ga.gif"/> </p>Aarash Y. N. Sofla, Cristina Martin <br/> (Technical Note from Lab Chip)<br/> Aarash Y. N. Sofla, Lab Chip, 2010, DOI: 10.1039/b917295e<br/> To cite this article before page numbers are assigned, use the DOI form of citation above. <br/>The content of this RSS Feed (c) The Royal Society of Chemistry A vapor-assisted method for adhering polydimethylsiloxane and glass Aarash Y. N. Sofla Cristina Martin 10.1039/b917295e Lab Chip, 2010, DOI: 10.1039/b917295e html/pdf 2009-11-12 The Royal Society of Chemistry Copyright (c) 2010 The Royal Society of Chemistry DOI 10.1039/b917295e http://xlink.rsc.org/?DOI=b914709h&RSS=1 Novel multifunctional materials based on ionogels have been used as light-actuated valve structures in micro-fluidic platforms. Through variation of the composition of the ionogels, the micro-valves can be tuned to open at different times under similar illumination conditions.<p><img align="center" src="http://www.rsc.org/ejga/LC/2010/b914709h-ga.gif"/> </p>Fernando Benito-Lopez, Robert Byrne, Ana Maria Raduta, Nihal Engin Vrana, Garrett McGuinness, Dermot Diamond <br/> (Paper from Lab Chip)<br/> Fernando Benito-Lopez, Lab Chip, 2010, DOI: 10.1039/b914709h<br/> To cite this article before page numbers are assigned, use the DOI form of citation above. <br/>The content of this RSS Feed (c) The Royal Society of Chemistry Ionogel-based light-actuated valves for controlling liquid flow in micro-fluidic manifolds Fernando Benito-Lopez Robert Byrne Ana Maria Raduta Nihal Engin Vrana Garrett McGuinness Dermot Diamond 10.1039/b914709h Lab Chip, 2010, DOI: 10.1039/b914709h html/pdf 2009-11-11 The Royal Society of Chemistry Copyright (c) 2010 The Royal Society of Chemistry DOI 10.1039/b914709h http://xlink.rsc.org/?DOI=b922116f&RSS=1 Petra Dittrich reviews the current literature in miniaturisation and related technologies.<p><img align="center" src="http://www.rsc.org/ejga/LC/2009/b922116f-ga.gif"/> </p> (Highlight from Lab Chip)<br/> Lab Chip, 2009, DOI: 10.1039/b922116f<br/> To cite this article before page numbers are assigned, use the DOI form of citation above. <br/>The content of this RSS Feed (c) The Royal Society of Chemistry Research Highlights RSC 10.1039/b922116f Lab Chip, 2009, DOI: 10.1039/b922116f html/pdf 2009-11-10 The Royal Society of Chemistry Copyright (c) 2010 The Royal Society of Chemistry DOI 10.1039/b922116f http://xlink.rsc.org/?DOI=b913312g&RSS=1 We have separated the cargo attachment from the transport mechanism by using micromachined nano-needles as carriers in a gliding assay-based system. Microtubule-independent functionalization diversifies the possibility for target molecule attachment without sacrificing the transport characteristics.<p><img align="center" src="http://www.rsc.org/ejga/LC/2010/b913312g-ga.gif"/> </p>Mehmet C. Tarhan, Ryuji Yokokawa, Celine Bottier, Dominique Collard, Hiroyuki Fujita <br/> (Paper from Lab Chip)<br/> Mehmet C. Tarhan, Lab Chip, 2010, DOI: 10.1039/b913312g<br/> To cite this article before page numbers are assigned, use the DOI form of citation above. <br/>The content of this RSS Feed (c) The Royal Society of Chemistry A nano-needle/microtubule composite gliding on a kinesin-coated surface for target molecule transport Mehmet C. Tarhan Ryuji Yokokawa Celine Bottier Dominique Collard Hiroyuki Fujita 10.1039/b913312g Lab Chip, 2010, DOI: 10.1039/b913312g html/pdf 2009-11-10 The Royal Society of Chemistry Copyright (c) 2010 The Royal Society of Chemistry DOI 10.1039/b913312g http://xlink.rsc.org/?DOI=b917760b&RSS=1 Preclinical absorption, distribution, metabolism, excretion and toxicity data are expensive to generate. We propose that such data are precompetitive in nature and should be made freely available on the web to prevent repetition, save costs and improve drug development.<p><img align="center" src="http://www.rsc.org/ejga/LC/2010/b917760b-ga.gif"/> </p>Sean Ekins, Antony J. Williams <br/> (Perspective from Lab Chip)<br/> Sean Ekins, Lab Chip, 2010, DOI: 10.1039/b917760b<br/> To cite this article before page numbers are assigned, use the DOI form of citation above. <br/>The content of this RSS Feed (c) The Royal Society of Chemistry Precompetitive preclinical ADME/Tox data: set it free on the web to facilitate computational model building and assist drug development Sean Ekins Antony J. Williams 10.1039/b917760b Lab Chip, 2010, DOI: 10.1039/b917760b html/pdf 2009-11-10 The Royal Society of Chemistry Copyright (c) 2010 The Royal Society of Chemistry DOI 10.1039/b917760b http://xlink.rsc.org/?DOI=b908759a&RSS=1 A polymer chip with integrated optics for high-throughput fluorescence detection consisting of a monolithic prism steering excitation light into an embedded waveguide situated orthogonal to a series of fluidic channels.<p><img align="center" src="http://www.rsc.org/ejga/LC/2010/b908759a-ga.gif"/> </p>Paul I. Okagbare, Jason M. Emory, Proyag Datta, Jost Goettert, Steven A. Soper <br/> (Paper from Lab Chip)<br/> Paul I. Okagbare, Lab Chip, 2010, DOI: 10.1039/b908759a<br/> To cite this article before page numbers are assigned, use the DOI form of citation above. <br/>The content of this RSS Feed (c) The Royal Society of Chemistry Fabrication of a cyclic olefin copolymer planar waveguide embedded in a multi-channel poly(methyl methacrylate) fluidic chip for evanescence excitation Paul I. Okagbare Jason M. Emory Proyag Datta Jost Goettert Steven A. Soper 10.1039/b908759a Lab Chip, 2010, DOI: 10.1039/b908759a html/pdf 2009-11-04 The Royal Society of Chemistry Copyright (c) 2010 The Royal Society of Chemistry DOI 10.1039/b908759a http://xlink.rsc.org/?DOI=b913494h&RSS=1 During inflammation neutrophils modulate their sensitivity to various chemotactic factor gradients to find the most direct path to the damaged or infected site. Keenan et al. describe a new method for examining gradient-induced homologous and heterologous neutrophil desensitization using a previously-developed open-chamber microfluidic gradient generator.<p><img align="center" src="http://www.rsc.org/ejga/LC/2010/b913494h-ga.gif"/> </p>Thomas M. Keenan, Charles W. Frevert, Aileen Wu, Venus Wong, Albert Folch <br/> (Method from Lab Chip)<br/> Thomas M. Keenan, Lab Chip, 2010, DOI: 10.1039/b913494h<br/> To cite this article before page numbers are assigned, use the DOI form of citation above. <br/>The content of this RSS Feed (c) The Royal Society of Chemistry A new method for studying gradient-induced neutrophil desensitization based on an open microfluidic chamber Thomas M. Keenan Charles W. Frevert Aileen Wu Venus Wong Albert Folch 10.1039/b913494h Lab Chip, 2010, DOI: 10.1039/b913494h html/pdf 2009-11-03 The Royal Society of Chemistry Copyright (c) 2010 The Royal Society of Chemistry DOI 10.1039/b913494h http://xlink.rsc.org/?DOI=b916548g&RSS=1 Biofabrication exploits biologically derived materials and biocatalysts for fabrication. This paper reports the in situ biofabrication of a freestanding biopolymer membrane structure using a pH gradient generated at a flow interface in microfluidics.<p><img align="center" src="http://www.rsc.org/ejga/LC/2010/b916548g-ga.gif"/> </p>Xiaolong Luo, Dean Larios Berlin, Jordan Betz, Gregory F. Payne, William E. Bentley, Gary W. Rubloff <br/> (Paper from Lab Chip)<br/> Xiaolong Luo, Lab Chip, 2010, DOI: 10.1039/b916548g<br/> To cite this article before page numbers are assigned, use the DOI form of citation above. <br/>The content of this RSS Feed (c) The Royal Society of Chemistry In situ generation of pH gradients in microfluidic devices for biofabrication of freestanding, semi-permeable chitosan membranes Xiaolong Luo Dean Larios Berlin Jordan Betz Gregory F. Payne William E. Bentley Gary W. Rubloff 10.1039/b916548g Lab Chip, 2010, DOI: 10.1039/b916548g html/pdf 2009-11-03 The Royal Society of Chemistry Copyright (c) 2010 The Royal Society of Chemistry DOI 10.1039/b916548g http://xlink.rsc.org/?DOI=b911953a&RSS=1 We demonstrate a method for improved surface plasmon resonance (SPR) biosensing by integrating active microfluidic mixing directly onto an SPR substrate. On-chip mixing via surface acoustic waves (SAW) results in accelerated binding kinetics and reduced non-specific binding.<p><img align="center" src="http://www.rsc.org/ejga/LC/2010/b911953a-ga.gif"/> </p>Alan Renaudin, Vincent Chabot, Etienne Grondin, Vincent Aimez, Paul G. Charette <br/> (Paper from Lab Chip)<br/> Alan Renaudin, Lab Chip, 2010, DOI: 10.1039/b911953a<br/> To cite this article before page numbers are assigned, use the DOI form of citation above. <br/>The content of this RSS Feed (c) The Royal Society of Chemistry Integrated active mixing and biosensing using surface acoustic waves (SAW) and surface plasmon resonance (SPR) on a common substrate Alan Renaudin Vincent Chabot Etienne Grondin Vincent Aimez Paul G. Charette 10.1039/b911953a Lab Chip, 2010, DOI: 10.1039/b911953a html/pdf 2009-11-03 The Royal Society of Chemistry Copyright (c) 2010 The Royal Society of Chemistry DOI 10.1039/b911953a http://xlink.rsc.org/?DOI=b915516c&RSS=1 The combination of open-sandwich ELISA and microfluidics allowed rapid and sensitive diagnosis of osteocalcin C-terminal peptide in serum.<p><img align="center" src="http://www.rsc.org/ejga/LC/2010/b915516c-ga.gif"/> </p>Masaki Ihara, Amane Yoshikawa, Yushu Wu, Hiroko Takahashi, Kazuma Mawatari, Kiyohito Shimura, Kae Sato, Takehiko Kitamori, Hiroshi Ueda <br/> (Paper from Lab Chip)<br/> Masaki Ihara, Lab Chip, 2010, DOI: 10.1039/b915516c<br/> To cite this article before page numbers are assigned, use the DOI form of citation above. <br/>The content of this RSS Feed (c) The Royal Society of Chemistry Micro OS-ELISA: Rapid noncompetitive detection of a small biomarker peptide by open-sandwich enzyme-linked immunosorbent assay (OS-ELISA) integrated into microfluidic device Masaki Ihara Amane Yoshikawa Yushu Wu Hiroko Takahashi Kazuma Mawatari Kiyohito Shimura Kae Sato Takehiko Kitamori Hiroshi Ueda 10.1039/b915516c Lab Chip, 2010, DOI: 10.1039/b915516c html/pdf 2009-11-03 The Royal Society of Chemistry Copyright (c) 2010 The Royal Society of Chemistry DOI 10.1039/b915516c http://xlink.rsc.org/?DOI=b917147a&RSS=1 To enhance the potential of passive pumping, a new 'micro passive pumping' technique has been developed that allows for high throughput fluidic delivery by combining passive pumping with a small droplet-based fluidic ejection system.<p><img align="center" src="http://www.rsc.org/ejga/LC/2009/b917147a-ga.gif"/> </p>Pedro J. Resto, Brian J. Mogen, Erwin Berthier, Justin C. Williams <br/> (Communication from Lab Chip)<br/> Pedro J. Resto, Lab Chip, 2009, DOI: 10.1039/b917147a<br/> To cite this article before page numbers are assigned, use the DOI form of citation above. <br/>The content of this RSS Feed (c) The Royal Society of Chemistry An automated microdroplet passive pumping platform for high-speed and packeted microfluidic flow applications Pedro J. Resto Brian J. Mogen Erwin Berthier Justin C. Williams 10.1039/b917147a Lab Chip, 2009, DOI: 10.1039/b917147a html/pdf 2009-10-30 The Royal Society of Chemistry Copyright (c) 2010 The Royal Society of Chemistry DOI 10.1039/b917147a http://xlink.rsc.org/?DOI=b911973f&RSS=1 Low-power microfluidic electro-hydraulic pumps utilize the principle of hydraulics to deliver fluids at precise flow rates while the novel design successfully separates the reagent fluid from the electrolytic fluid.<p><img align="center" src="http://www.rsc.org/ejga/LC/2010/b911973f-ga.gif"/> </p>Clarissa Lui, Scott Stelick, Nathaniel Cady, Carl Batt <br/> (Paper from Lab Chip)<br/> Clarissa Lui, Lab Chip, 2010, DOI: 10.1039/b911973f<br/> To cite this article before page numbers are assigned, use the DOI form of citation above. <br/>The content of this RSS Feed (c) The Royal Society of Chemistry Low-power microfluidic electro-hydraulic pump (EHP) Clarissa Lui Scott Stelick Nathaniel Cady Carl Batt 10.1039/b911973f Lab Chip, 2010, DOI: 10.1039/b911973f html/pdf 2009-10-30 The Royal Society of Chemistry Copyright (c) 2010 The Royal Society of Chemistry DOI 10.1039/b911973f http://xlink.rsc.org/?DOI=b915979g&RSS=1 In this paper, the development of a novel low power (mW), low current (mA) AC microfluidic pump is described that is capable of generating kPa head pressures.<p><img align="center" src="http://www.rsc.org/ejga/LC/2009/b915979g-ga.gif"/> </p>Chien-Chih Huang, Martin Z. Bazant, Todd Thorsen <br/> (Paper from Lab Chip)<br/> Chien-Chih Huang, Lab Chip, 2009, DOI: 10.1039/b915979g<br/> To cite this article before page numbers are assigned, use the DOI form of citation above. <br/>The content of this RSS Feed (c) The Royal Society of Chemistry Ultrafast high-pressure AC electro-osmotic pumps for portable biomedical microfluidics Chien-Chih Huang Martin Z. Bazant Todd Thorsen 10.1039/b915979g Lab Chip, 2009, DOI: 10.1039/b915979g html/pdf 2009-10-29 The Royal Society of Chemistry Copyright (c) 2010 The Royal Society of Chemistry DOI 10.1039/b915979g http://xlink.rsc.org/?DOI=b913912e&RSS=1 A "microfluidic probe" is presented, which allows rapid and repeatable, simultaneous on-wafer fluidic and electronic probing. The probes are easily fabricated using standard soft-lithography.<p><img align="center" src="http://www.rsc.org/ejga/LC/2010/b913912e-ga.gif"/> </p>David A. Routenberg, Mark A. Reed <br/> (Technical Note from Lab Chip)<br/> David A. Routenberg, Lab Chip, 2010, DOI: 10.1039/b913912e<br/> To cite this article before page numbers are assigned, use the DOI form of citation above. <br/>The content of this RSS Feed (c) The Royal Society of Chemistry Microfluidic probe: a new tool for integrating microfluidic environments and electronic wafer-probing David A. Routenberg Mark A. Reed 10.1039/b913912e Lab Chip, 2010, DOI: 10.1039/b913912e html/pdf 2009-10-29 The Royal Society of Chemistry Copyright (c) 2010 The Royal Society of Chemistry DOI 10.1039/b913912e