RSC Biomolecular Sciences
Protein-Carbohydrate Interactions in Infectious Diseases
Stephen Neidle (Editor), Carole A Bewley (Editor)
Protein-carbohydrate interactions is an exciting area of research with huge potential for development and exploration. These interactions are both widespread and diverse in biological processes and many play a crucial role in cellular recognition, attachment and adhesion. This is particularly true for host-pathogen interactions that lead to infectious diseases; as the surfaces of cells and pathogens display complex carbohydrate structures and carbohydrate binding proteins on their surface. Protein-Carbohydrate Interactions in Infectious Disease is part of the Biomolecular Science Series and provides a comprehensive overview of the subject, with contributions from leading experts in the field. Beginning with a general introduction, subsequent sections include: Atomic basis of protein-carbohydrate interactions, Structures and roles of Pseudomonas areuginosa lectins, Protein-carbohydrate interactions in enterobacterial infections, Retrocyclins: miniature lectins with potent antiviral activity, C-type lectin receptors that regulate pathogen recognition through the recognition of carbohydrates, Synthetic carbohydrate-based anti-malarial vaccines and glycobiology. With full colour throughout and an extensive bibliography this book is ideal for researchers interested in the area.
"It is a welcome addition to the collections of scientists working in the area.""The book whets the appetite of structural biologists like me who are interested in protein-carbohydrate interactions."
Source : Crystallography Reviews
....is a valuable source of knowledge in this area not only for graduate students but also for non-specialist readers.
Source : International Journal of Biological Macromolecules, 29 November 2006 (John F Kennedy)