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Caption : figure s1. dsc analysis of the mpns treated at a) 130°c and b) 200°c.

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Caption : figure s2. infrared analysis of mpns treated at 130°c and 200°c.

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Caption : figure s3. sem of the mpns.

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Caption : figure s4. xps analysis of ompns, a) elemental spectrum, b) c1s spectrum, c) o1s spectrum and d) n1s spectrum.

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Caption : figure s5. infrared analysis of the mpns, ompns and ompn-pei.

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Caption : figure s6. cell viability of huvec incubated with ompn-pei and ompn-pei@oligo-dna.

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Caption : figure s7. fluorescence microscopy images of huvec incubated with ompn-pei (scale bar: 50 µm).

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Caption : figure s8. fluorescence microscopy images of huvec incubated with ompn-pei@oligo-dna (scale bar: 50 µm).

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Caption : figure s9. h&e staining and immunofluorescence images of huvec (scale bar: 50 µm).

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Caption : figure s10. h&e stained images of major organs (heart, liver, kidney, lung and spleen) sections after treatment (scale bar: 50 μm).