Additions
The use of enzymes in organic synthesis and the life sciences: perspectives from the Swiss Industrial Biocatalysis Consortium (SIBC)
Hans-Peter Meyer, Eric Eichhorn, Steven Hanlon, Stephan Lütz, Martin Schürmann, Roland Wohlgemuth and Raffaella Coppolecchia
Catal. Sci. Technol., 2013, 3, 29–40 (DOI: 10.1039/C2CY20350B). Amendment published 16th January 2013.
The authors wish to note that this Perspective was written by a group of
scientists from international and global companies, active in very different
areas and markets. The purpose was to give an inside view and opinions on biocatalysis from an industrial environment in order to
foster industry–university communication. Therefore, this industrial
contribution is different from a review paper with a comprehensive list of
references. However, to provide some more background information for readers,
the authors would like to add the following references:
Page 29, left column after the sentence beginning “However, despite
these and other applications of enzymatic reactions also run at industrial
scale…”
the reference, M. C. R. Franssen, M. Kircher, R. Wohlgemuth,
Industrial Biotechnology in the Chemical and Pharmaceutical Industries, in Industrial
Biotechnology, Sustainable Growth and Economic Success, ed. W. Soetaert and E. J. Vandamme,
Wiley-VCH, Weinheim, 2010, should be added.
Page 34, left column after the sentence “They do not require cofactors,
are easily available at large scale and a broad range of hydrolases has been
well characterized with predictable results.”
the reference, R. J. Kazlauskas
and U. T. Bornscheuer, Hydrolases in organic
synthesis, Wiley-VCH, Weinheim, 2006, should be
added.
Page 34, right column after the sentence “Although the development of
both enantiotope-selective hydrolyses of prochiral acylated diols and dicarboxylic esters in
aqueous buffers as well as enantiotope-selective
acylation of prochiral diols
has been developed decades ago, short synthetic routes to valuable chiral
compounds from easily accessible starting materials are still of industrial
interest.”
the references,
R. Wohlgemuth, Large-scale applications of hydrolases
in biocatalytic asymmetric synthesis, in, Large-scale
asymmetric catalysis, ed. H. U. Blaser and H. J. Federsel, Wiley-VCH, Weinheim,
2010
and
E. Egholm Jacobsen, A. Lie, M. M. Hansen Frigstad, M. Farrag El-Behairy, T. Ljones, R. Wohlgemuth, T. Anthonsen, J.
Mol. Catal. B: Enzymatic 2013, 134, 85-86,
should be included.
Page 35, left column after the sentence beginning “Esterases
have proven to be useful biocatalysts in the desymmetrization
of a variety of prochiral glutaric
esters, e.g. in the desymmetrization of
dimethyl 3-hydroxy-3-methylglutarate…”, the references:
R. Wohlgemuth, Large-scale applications of hydrolases
in biocatalytic asymmetric synthesis, in, Large-scale
asymmetric catalysis, ed. H. U. Blaser and H. J. Federsel, Wiley-VCH, Weinheim,
2010 and
R. Wohlgemuth, Green Production of Fine Chemicals by
Isolated Enzymes, in, Biocatalysis for
Green Chemistry and Chemical Process Development, ed. J. A. Tao and R. Kazlauskas, John Wiley & Sons Ltd, 2011, should be
included.
Page 35, left column after the sentence “ .. or by epoxide hydrolase-catalyzed
ring-opening reactions of the corresponding epoxides.”
the reference: M. Kotik, A. Archelas
and R. Wohlgemuth, Curr.
Org. Chem., 2012, 16, 451, should be included.
Page 35 The reference, R. Wohlgemuth,
Large-Scale Applications of Biocatalysis in the
Asymmetric Synthesis of Laboratory Chemicals, in, Asymmetric Catalysis on
Industrial Scale ,
ed. H. U. Blaser and E. Schmidt, Wiley-VCH, Weinheim, 2004, should be added alongside Figure 5.
Page 37, left column The activity for acetone reported by Wong and
co-workers should read 0.7%
Page 37, right column after the sentence, “On the other hand the FSA
variants containing the Ala129Ser exchange had higher activities with dihydroxyacetone and AASM compared to hydroxyacetone
(data not shown).”
the reference, M. Schürmann, P. Alsters
and T. Netscher, DSM, 2006, unpublished work, should
be included.
Page 37, right column after the sentence “The specific activity and
volumetric productivity for this reaction was lower than with HA, but still in
a high range compared to the physiological substrates (Table 5)”,
the reference: M. Schürmann and G. A. Sprenger, J. Biol. Chem., 2001, 276, 11055,
should be included (reference 30).
Page 37, right column after the sentence, “Most of the subsequent steps
towards (+)-biotin were proven to be feasible and efficient as well (to be
published elsewhere or reported before).”
the reference: M. Schürmann, P. Alsters
and T. Netscher, DSM, 2006, unpublished work, should
be added.
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