File Name : esi fig s1 fin.tif

Caption : figure s1. comparison of h&e staining images of the tissue cross-sections (<b>a</b>) with marked micrometastasis area (<b>1-3</b>); (<b>b-d</b>) false-colour molecular map combined from cars, tpef and shg images for the adjacent lung cross-section with selected areas (red) corresponding to the localization of cancer cells cluster from <b>a</b>.

File Name : esi fig s2 fin.tif

Caption : figure s2. mean normal ft-ir spectra extracted from the uhca cluster maps (<b>3a-c</b>) before (<b>1a-c</b>) and after (<b>2a-c</b>) without rmies emsc correction. orange spectrum contains bands characteristic for oct (c.a. 1730,1247,1100cm<sup>-1</sup>), therefore is not display in fig.1. the colours of spectra correspond to the colours of the classes.