Additions and corrections
Synthesis and use of isotope-labelled substrates for a mechanistic study on human α-methylacyl-CoA racemase 1A (AMACR; P504S)
Daniel J. Darley, Danica S. Butler, Samuel J. Prideaux, Thomas W. Thornton, Abigail D. Wilson, Timothy J. Woodman, Michael D. Threadgill and Matthew D. Lloyd
Organic & Biomolecular Chemistry, 2009, 7, 543–552, DOI: 10.1039/b815396e Amendment published 1st July 2009
The authors regret the following error:
During the course of subsequent studies it has come to our attention that the enzyme kinetic parameters for substrates 10S and 10R were incorrectly reported. The correct parameters are as follows: Km = 1.2 mM; Vmax = 77.5 nmol min-1 mg-1; kcat = 6.09 x 10-2 s-1; kcat/Km = 50.75 s-1 M-1. For 10R: Km = 1.2 mM; Vmax = 68.4 nmol min-1 mg-1; kcat = 5.38 x 10-2 s-1; kcat/Km = 44.80 s-1 M-1.
This error is at the bottom of p. 545 and the top of p. 546.
The Royal Society of Chemistry apologises for this error and any consequent inconvenience to authors and readers.