Professor John Hunt FRSC
John’s research focuses on developing breakthrough therapies, devices and technology to repair, replace, augment and in the future regenerate diseased, infected and damaged tissues in humans and other mammals using material interventions. Understanding the generic science to deliver interventional medical therapies requiring the use of a material (living cells are also considered to be a material). These will come from an in depth generic first principles approach to understanding and directing the patient’s cellular and molecular mechanisms and responses related to the clinical outcome and efficacy of medical devices, biocompatibility, inflammation and stem cell biology. Tissue engineering processes are developed and applied, addressing the key areas of patient treatments requiring intervention and material implantation; the materials of choice being researched today also include cells and within that, expertise and intellectual property has been created relating to primary cell sourcing, controlling cell function and phenotype through defining and controlling extracellular matrix interactions, angiogenesis, inflammation and tissue regeneration.
From a strong long lived generic research platform, specific applications and knowledge has been applied to and continue to be developed for musculoskeletal tissues specifically cartilage and bone, visceral and vascular tissues. Professor Hunt’s research has been funded by the European Commission, BBSRC, MRC and EPSRC as well as by Industry. Ph.D in 1992 and D.Sc. in 2006.
He is a Fellow of the Royal Society of Chemistry, a Fellow of the International College of Fellows for Biomaterials Science and Engineering and elected committee member and the treasurer of the society. He is an honorary clinical academic consultant at the Liverpool Heart and Chest NHS trust hospital and an honorary Professor at University of Liverpool. He is a full time Professor and research Theme Leader at Nottingham Trent University; leading the theme Medical Technologies and Advanced Materials. He is on the International editorial board member for the journal Biomaterials and the Biomaterials and Nanotechnology section editor in the International journal of Artificial Organs.
Dr Henry Day MRSC CChem
Analytical Chemist in the consumables product development team at Illumina in Cambridge. For my undergraduate degree I studied Natural Sciences at St. Catharine’s College Cambridge where I specialised in Organic Chemistry. My interest in analytical chemistry developed during my PhD in the School of Pharmacy, University of East Anglia where I was investigating small molecule interactions with alternative DNA secondary structures. During this time my eyes were opened to a wealth of analytical techniques for investigating DNA structure and DNA-ligand interactions.
After completing my PhD I stayed with the analytical sciences in industry working for LGC group in the sport and specialised analytical sciences team. Here I gained a great deal of experience of LC-MS carrying out method development and validation for the analysis of small molecules in biological matrices. Now in my current role I have moved back to the field of Nucleic Acids where my real passion lies and I am applying my expertise in HPLC, LC-MS and other Biophysical and Analytical methods to Illumina’s world-renowned sequencing technology.
Mr Ken Fantom MRSC
Ken Fantom, (Secretary) Senior Investigator in Biomolecular Analysis section at GlaxoSmithKline. Our research utilises state-of-the-art mass spectrometry in protein analysis and proteomics to investigate the identity, quantity and molecular composition of proteins as well as of cellular metabolites.
Dr Frankie Rawson
Frankie is currently an independent Senior Research Fellow based in the Laboratory of Biophysics and Surface Analysis within the School of Pharmacy at the University of Nottingham. His research interests span the boundary of chemistry and biology and a key area is to develop and nano-electrochemical systems for studying biological electron transfer processes. Thereby, providing new insights into the biological role that redox chemistry plays in modulating cell function. One exciting application of such technology is in the newly coined field of “electroceutics”. Future progress in this field requires both simultaneous sensing and electrical actuation of cell behaviour and is in part what his group are striving towards.
Dr Nikola Chmel MRSC
Senior Teaching Fellow in the Department of Chemistry at the University of Warwick. My research interests include development of new methods in polarised light spectroscopy for applications in biochemistry. I am also responsible for the transferrable skills training programme for the Faculties of Science and Medicine at the University of Warwick.
Dr Lynn Dennany MRSC
Lecturer at University of Strathclyde. My research interests focus on the application of analytical detection techniques for chemical and biochemical sensor development. I am particularly interested in the creation of novel materials that have tuneable electronic or photonic properties. These materials can be utilised for new applications in a variety of areas ranging from biomedical devices to forensic applications.
Lynn Dennany Website
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Professor Mark Dickman MRSC
I obtained my PhD in the Department of Chemistry at the University of Sheffield. Following my PhD I joined a biotechnology company, Transgenomic LTD where I worked as a research scientist developing analytical techniques including DNA/RNA Chromatography. I joined the Dept of Chemical and Biological Engineering in 2003 where I am currently a Professor in Bioanalytical Science and Engineering.
My research focuses on the development and application analytical techniques to study biological systems. In particular, biological mass spectrometry in conjunction with bioseparations have been utilised to study a wide variety of biological systems. Using these analytical approaches we are interested in identifying and characterising biomolecules including proteins and nucleic acids.
I am member of number of research centres/institutes at the University of Sheffield including the Krebs Institute, Advanced Biomanufacturing Centre (ABC) and the Sheffield Institute for Nucleic Acids I am currently the Director of Research in the Department of Chemical and Biological Engineering.
Professor Mark Dickman MRSC
University of Sheffield
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Dr Stefanie Frank
Lecturer in Synthetic Biology at the Department of Biochemical Engineering at UCL. My work is focused on the engineering of microbial metabolic pathways and the spatial organisation of enzymes for biotechnology applications. This involves the use of various analytical techniques for the elucidation of protein structure-function relationships and metabolite detection.
Dr Kirsty High MRSC
Knowledge Exchange Fellow in Analytical Chemistry at the University of York. I am interested in the application of analytical chemistry to the study of organic archaeological materials, in particular understanding how they deteriorate in the burial environment. I spend a lot of time working with archaeologists and heritage management professionals to develop ways of understanding how human impacts on the environment cause damage to archaeology. The chemical analysis of biopolymers, and correlating changes to the altering the geochemistry of the burial environment play a key role in this.
Dr Deborah Mawson CSci CChem MRSC
Principal Scientist at LGC. I lead the innovation team within the Sport and Specialised Analytical Services department at Fordham. Much of the focus of the team is the development and validation of multi-analyte, quantitative assays for endogenous compounds in diverse matrices e.g. plasma, urine, saliva, sweat and dried blood spots. In addition to designing (or leading the development of) robust quantitative UPLC-MS/MS assays, I carry out hands on and operational theory training of LC-MS systems and troubleshoot problematic methods. Prior to working at LGC, I completed a PhD at the University of York conducting structural elucidation of organic geoporphyrins using LC-MSn.
Dr Mark Seymour CChem FRSC
Syngenta Fellow in Analytical Sciences at Syngenta’s Jealott’s Hill International Research Centre. After completing his PhD in Analytical Chemistry, Mark spent 2 years carrying out analytical development work in the pharmaceutical industry. He then moved into chemical manufacturing spending 8 years as a QC manager before joining the agrochemical industry where he has held various positions. Mark now leads Syngenta's global measurement science network.
Dr Andrew Kenyon
CEO of BioClone Ltd., a London based consultancy company specialising in biopharmaceutical project management, analytical process validation and regulatory guidance. Our areas of interest range from early R&D through to manufacture and pharmacovigilance.