Reaction Details

Mislow-Evans Rearrangement

[2,3]-Sigmatropic rearrangement of allylic sulfoxides to allylic sulfenates which are captured by thiophiles to generate the allylic alcohols, thereby effecting the 1,3-transposition of sulfoxide and alcohol functions. The reverse process is accomplished by treating the alcohol with arylsulfenyl chloride, followed by thermal rearrangement of the sulfenate to generate the allylic sulfoxide:

Mislow-Evans Rearrangement

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