MedChemComm
2040-2503
Royal Society of Chemistry
Front cover
10.1039/c3md90001k
AuthorAnonymous
2013
4
2
297
298
Abstract
HTML
PDF
other
MedChemComm
2040-2503
Royal Society of Chemistry
Contents list
10.1039/c3md90002a
AuthorAnonymous
2013
4
2
299
308
Abstract
HTML
PDF
other
MedChemComm
2040-2503
Royal Society of Chemistry
European Federation for Medicinal Chemistry in partnership with <i>MedChemComm</i>
10.1039/c2md90050e
AuthorAnonymous
2013
4
2
309
309
Abstract
HTML
PDF
editorial
MedChemComm
2040-2503
Royal Society of Chemistry
Preparation and evaluation of BBB-permeable trehalose derivatives as potential therapeutic agents for Huntington's disease
10.1039/c2md20112g
Im
Jungkyun
Kim
Sangjune
Jeong
Young-Hun
Kim
Wanil
Lee
Dohyun
Lee
Woo Sirl
Chang
Young-Tae
Kim
Kyong-Tai
Chung
Sung-Kee
2013
4
2
310
316
Abstract
HTMLPDF
research-article
MedChemComm
2040-2503
Royal Society of Chemistry
Selective antitumour activity and ERα molecular docking studies of newly synthesized d-homo fused steroidal tetrazoles
10.1039/c2md20327h
Penov-Gaši
Katarina M.
Oklješa
Aleksandar M.
Petri
Edward T.
Ćelić
Andjelka S.
Djurendić
Evgenija A.
Klisurić
Olivera R.
Csanadi
Janos J.
Batta
Gyula
Nikolić
Andrea R.
Jakimov
Dimitar S.
Sakač
Marija N.
2013
4
2
317
323
Abstract
HTMLPDF
research-article
MedChemComm
2040-2503
Royal Society of Chemistry
Novel FK506 and FK520 analogues <i>via</i> mutasynthesis: mutasynthon scope and product characteristics
10.1039/c2md20266b
Moss
Steven J.
Stanley-Smith
Anna E.
Schell
Ursula
Coates
Nigel J.
Foster
Teresa A.
Gaisser
Sabine
Gregory
Matthew A.
Martin
Christine J.
Nur-e-Alam
Mohammad
Piraee
Mahmood
Radzom
Markus
Suthar
Dipen
Thexton
David G.
Warneck
Tony D.
Zhang
Ming-Qiang
Wilkinson
Barrie
2013
4
2
324
331
Abstract
HTMLPDF
research-article
MedChemComm
2040-2503
Royal Society of Chemistry
Relative impact of 3- and 5-hydroxyl groups of cytosporone B on cancer cell viability
10.1039/c2md20243c
Xia
Zebin
Cao
Xihua
Rico-Bautista
Elizabeth
Yu
Jinghua
Chen
Liqun
Chen
Jiebo
Bobkov
Andrey
Wolf
Dieter A.
Zhang
Xiao-Kun
Dawson
Marcia I.
2013
4
2
332
339
Abstract
HTMLPDF
research-article
MedChemComm
2040-2503
Royal Society of Chemistry
Dinaphthonaphthyridines – a class of novel molecules with potent antioxidant and anticancer activity
10.1039/c2md20270k
Prabha
K.
Prasad
K. J. Rajendra
2013
4
2
340
346
Abstract
HTMLPDF
research-article
MedChemComm
2040-2503
Royal Society of Chemistry
A new class of fluorinated 5-pyrrolidinylsulfonyl isatin caspase inhibitors for PET imaging of apoptosis
10.1039/c2md20249b
Krause-Heuer
Anwen M.
Howell
Nicholas R.
Matesic
Lidia
Dhand
Geetanjali
Young
Emma L.
Burgess
Leena
Jiang
Cathy D.
Lengkeek
Nigel A.
Fookes
Christopher J. R.
Pham
Tien Q.
Sobrio
Franck
Greguric
Ivan
Fraser
Benjamin H.
2013
4
2
347
352
Abstract
HTMLPDF
research-article
MedChemComm
2040-2503
Royal Society of Chemistry
Structure–activity relationships of tetrahydrocarbazole derivatives as antifungal lead compounds
10.1039/c2md20211e
Wang
Wenya
Dong
Guoqiang
Gu
Julin
Zhang
Yongqiang
Wang
Shengzheng
Zhu
Shiping
Liu
Yang
Miao
Zhenyuan
Yao
Jianzhong
Zhang
Wannian
Sheng
Chunquan
2013
4
2
353
362
Abstract
HTMLPDF
research-article
MedChemComm
2040-2503
Royal Society of Chemistry
A new route towards fimbrolide analogues: importance of the exomethylene motif in LuxR dependent quorum sensing inhibition
10.1039/c2md20298k
Sabbah
Mohamad
Bernollin
Maud
Doutheau
Alain
Soulère
Laurent
Queneau
Yves
2013
4
2
363
366
Abstract
HTMLPDF
research-article
MedChemComm
2040-2503
Royal Society of Chemistry
3,3-Dimethyl-1<i>H</i>-pyrrolo[3,2-<i>g</i>]quinolin-2(3<i>H</i>)-one derivatives as novel Raf kinase inhibitors
10.1039/c2md20275a
Li
Yanyang
Shi
Xiangfei
Xie
Ning
Zhao
Yanjin
Li
Shuxin
2013
4
2
367
370
Abstract
HTMLPDF
research-article
MedChemComm
2040-2503
Royal Society of Chemistry
Combination of biotransformation by P450 BM3 mutants with on-line post-column bioaffinity and mass spectrometric profiling as a novel strategy to diversify and characterize p38α kinase inhibitors
10.1039/c2md20283b
Rea
Vanina
Falck
David
Kool
Jeroen
Kanter
Frans J. J. de
Commandeur
Jan N. M.
Vermeulen
Nico P. E.
Niessen
Wilfried M. A.
Honing
Maarten
2013
4
2
371
377
Abstract
HTMLPDF
research-article
MedChemComm
2040-2503
Royal Society of Chemistry
Inhibition of Ras–effector interactions by cyclic peptides
10.1039/c2md20329d
Wu
Xianghong
Upadhyaya
Punit
Villalona-Calero
Miguel A.
Briesewitz
Roger
Pei
Dehua
2013
4
2
378
382
Abstract
HTMLPDF
research-article
MedChemComm
2040-2503
Royal Society of Chemistry
Synthesis of 1,4-triazole linked zanamivir dimers as highly potent inhibitors of influenza A and B
10.1039/c2md20300f
Fraser
Benjamin H.
Hamilton
Stephanie
Krause-Heuer
Anwen M.
Wright
Philip J.
Greguric
Ivan
Tucker
Simon P.
Draffan
Alistair G.
Fokin
Valery V.
Sharpless
K. Barry
2013
4
2
383
386
Abstract
HTMLPDF
research-article
MedChemComm
2040-2503
Royal Society of Chemistry
Glycosidase inhibition by novel guanidinium and urea iminosugar derivatives
10.1039/c2md20343j
Kooij
Raymond
Branderhorst
Hilbert M.
Bonte
Simon
Wieclawska
Sara
Martin
Nathaniel I.
Pieters
Roland J.
2013
4
2
387
393
Abstract
HTMLPDF
research-article
MedChemComm
2040-2503
Royal Society of Chemistry
Design, synthesis and crystal structure determination of dinuclear copper-based potential chemotherapeutic drug entities; <i>in vitro</i> DNA binding, cleavage studies and an evaluation of genotoxicity by micronucleus test and comet assay
10.1039/c2md20141k
Arjmand
Farukh
Muddassir
Mohd
Zaidi
Yusra
Ray
Debashis
2013
4
2
394
405
Abstract
HTMLPDF
research-article
MedChemComm
2040-2503
Royal Society of Chemistry
A structure–activity relationship study on multi-heterocyclic molecules: two linked thiazoles are required for cytotoxic activity
10.1039/c2md20291c
Kim
Seong Jong
Lin
Chun-Chieh
Pan
Chung-Mao
Rananaware
Dimple P.
Ramsey
Deborah M.
McAlpine
Shelli R.
2013
4
2
406
410
Abstract
HTMLPDF
research-article
MedChemComm
2040-2503
Royal Society of Chemistry
Identification of novel inhibitors of p53–MDM2 interaction facilitated by pharmacophore-based virtual screening combining molecular docking strategy
10.1039/c2md20208e
Wang
Weisi
Zhu
Xiaolei
Hong
Xueqin
Zheng
Lin
Zhu
Hong
Hu
Yongzhou
2013
4
2
411
416
Abstract
HTMLPDF
research-article
MedChemComm
2040-2503
Royal Society of Chemistry
Developing novel C-4 analogues of pyrrole-based antitubulin agents: weak but critical hydrogen bonding in the colchicine site
10.1039/c2md20320k
Da
Chenxiao
Telang
Nakul
Hall
Kayleigh
Kluball
Emily
Barelli
Peter
Finzel
Kara
Jia
Xin
Gupton
John T.
Mooberry
Susan L.
Kellogg
Glen E.
2013
4
2
417
421
Abstract
HTMLPDF
research-article
MedChemComm
2040-2503
Royal Society of Chemistry
Triazolopyrimidinones as γ-secretase modulators: structure–activity relationship, modulator profile, and <i>in vivo</i> profiling
10.1039/c2md20312j
Yngve
Ulrika
Paulsen
Kim
Macsari
Istvan
Sundström
Marie
Santangelo
Ellen
Linde
Christian
Bogar
Krisztian
Lake
Fredrik
Besidski
Yevgeni
Malmborg
Jonas
Strömberg
Kia
Appelkvist
Paulina
Radesäter
Ann-Cathrine
Olsson
Fredrik
Bergström
Daniel
Klintenberg
Rebecka
Arvidsson
Per I.
2013
4
2
422
431
Abstract
HTMLPDF
research-article
MedChemComm
2040-2503
Royal Society of Chemistry
The advantage of biosensor analysis over enzyme inhibition studies for slow dissociating inhibitors – characterization of hydroxamate-based matrix metalloproteinase-12 inhibitors
10.1039/c2md20268a
Gossas
Thomas
Nordström
Helena
Xu
Ming-Hua
Sun
Zhi-Hua
Lin
Guo-Qiang
Wallberg
Hans
Danielson
U. Helena
2013
4
2
432
442
Abstract
HTMLPDF
research-article
MedChemComm
2040-2503
Royal Society of Chemistry
Synthesis and <i>in vitro</i> biological evaluation of pyrazole group-containing analogues for PDE10A
10.1039/c2md20239e
Li
Junfeng
Jin
Hongjun
Zhou
Haiying
Rothfuss
Justin
Tu
Zhude
2013
4
2
443
449
Abstract
HTMLPDF
research-article
MedChemComm
2040-2503
Royal Society of Chemistry
Synthesis of hetero annulated carbazoles: exploration of <i>in vitro</i> cytotoxicity and molecular docking studies
10.1039/c2md20335a
Indumathi
Thangavel
Muthusankar
Aathi
Shanmughavel
P.
Prasad
K. J. Rajendra
2013
4
2
450
455
Abstract
HTMLPDF
research-article
MedChemComm
2040-2503
Royal Society of Chemistry
Identification of pyrazolo-pyrimidinones as GHS-R1a antagonists and inverse agonists for the treatment of obesity
10.1039/c2md20340e
McCoull
William
Barton
Peter
Broo
Anders
Brown
Alastair J. H.
Clarke
David S.
Coope
Gareth
Davies
Robert D. M.
Dossetter
Alexander G.
Kelly
Elizabeth E.
Knerr
Laurent
MacFaul
Philip
Holmes
Jane L.
Martin
Nathaniel
Moore
Jane E.
Morgan
David
Newton
Claire
Österlund
Krister
Robb
Graeme R.
Rosevere
Eleanor
Selmi
Nidhal
Stokes
Stephen
Svensson
Tor S.
Ullah
Victoria B. K.
Williams
Emma J.
2013
4
2
456
462
Abstract
HTMLPDF
research-article
MedChemComm
2040-2503
Royal Society of Chemistry
Back cover
10.1039/c3md90003g
AuthorAnonymous
2013
4
2
463
464
Abstract
HTML
PDF
other