MedChemComm
2040-2503
Royal Society of Chemistry
Front cover
10.1039/c3md90007j
AuthorAnonymous
2013
4
4
611
612
Abstract
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MedChemComm
2040-2503
Royal Society of Chemistry
Contents list
10.1039/c3md90010j
AuthorAnonymous
2013
4
4
613
618
Abstract
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MedChemComm
2040-2503
Royal Society of Chemistry
Methanocarba ring as a ribose modification in ligands of G protein-coupled purine and pyrimidine receptors: synthetic approaches
10.1039/c2md20348k
Tosh
Dilip K.
Jacobson
Kenneth A.
2013
4
4
619
630
Abstract
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review-article
MedChemComm
2040-2503
Royal Society of Chemistry
Metabolism-guided drug design
10.1039/c2md20317k
Stepan
Antonia F.
Mascitti
Vincent
Beaumont
Kevin
Kalgutkar
Amit S.
2013
4
4
631
652
Abstract
HTMLPDF
review-article
MedChemComm
2040-2503
Royal Society of Chemistry
Design and synthesis of novel <sup>18</sup>F-radiolabelled glucosamine derivatives for cancer imaging
10.1039/c3md00023k
Carroll
Laurence
Witney
Timothy H.
Aboagye
Eric O.
2013
4
4
653
656
Abstract
HTMLPDF
research-article
MedChemComm
2040-2503
Royal Society of Chemistry
Matched triplicate design sets in the optimisation of glucokinase activators – maximising medicinal chemistry information content
10.1039/c3md20367k
Waring
Michael J.
Bennett
Stuart N. L.
Boyd
Scott
Campbell
Leonie
Davies
Robert D. M.
Gerhardt
Stefan
Hargreaves
David
Martin
Nathaniel G.
Robb
Graeme R.
Wilkinson
Gary
2013
4
4
657
662
Abstract
HTMLPDF
research-article
MedChemComm
2040-2503
Royal Society of Chemistry
Optimising pharmacokinetics of glucokinase activators with matched triplicate design sets – the discovery of AZD3651 and AZD9485
10.1039/c3md20368a
Waring
Michael J.
Bennett
Stuart N. L.
Boyd
Scott
Campbell
Leonie
Davies
Robert D. M.
Hargreaves
David
MacFaul
Philip
Martin
Nathaniel G.
Ogg
Derek J.
Robb
Graeme R.
Wilkinson
Gary
Wood
J. Matthew
2013
4
4
663
668
Abstract
HTMLPDF
research-article
MedChemComm
2040-2503
Royal Society of Chemistry
Single-walled carbon nanotubes as anisotropic relaxation probes for magnetic resonance imaging
10.1039/c3md20235f
Cerpa
Arisbel
Köber
Mariana
Calle
Daniel
Negri
Viviana
Gavira
Jose María
Hernanz
Antonio
Briones
Fernando
Cerdán
Sebastián
Ballesteros
Paloma
2013
4
4
669
672
Abstract
HTMLPDF
research-article
MedChemComm
2040-2503
Royal Society of Chemistry
Increasing small molecule drug developability in sub-optimal chemical space
10.1039/c3md00003f
Ritchie
Timothy J.
Macdonald
Simon J. F.
Peace
Simon
Pickett
Stephen D.
Luscombe
Christopher N.
2013
4
4
673
680
Abstract
HTMLPDF
research-article
MedChemComm
2040-2503
Royal Society of Chemistry
Investigation of a tetrahydroisoquinoline scaffold as dual-action steroid sulfatase inhibitors generated by parallel solid-phase synthesis
10.1039/c3md20354a
Ouellet
Étienne
Maltais
René
Ouellet
Charles
Poirier
Donald
2013
4
4
681
692
Abstract
HTMLPDF
research-article
MedChemComm
2040-2503
Royal Society of Chemistry
Design of symmetrical and nonsymmetrical <i>N</i>,<i>N</i>-dimethylaminopyridine derivatives as highly potent choline kinase alpha inhibitors
10.1039/c3md00068k
Trousil
Sebastian
Carroll
Laurence
Kalusa
Andrew
Aberg
Ola
Kaliszczak
Maciej
Aboagye
Eric O.
2013
4
4
693
696
Abstract
HTMLPDF
research-article
MedChemComm
2040-2503
Royal Society of Chemistry
Design, synthesis and biological evaluation of imidazo[1,5-<i>a</i>]pyridine–PBD conjugates as potential DNA-directed alkylating agents
10.1039/c2md20219k
Kamal
Ahmed
Ramakrishna
G.
Ramaiah
M. Janaki
Viswanath
A.
Rao
A. V. Subba
Bagul
Chandrakant
Mukhopadyay
Debasmitha
Pushpavalli
S. N. C. V. L.
Pal-Bhadra
Manika
2013
4
4
697
703
Abstract
HTMLPDF
research-article
MedChemComm
2040-2503
Royal Society of Chemistry
Synthesis and antifungal activity of the novel triazole compounds
10.1039/c3md20086h
Yu
Shichong
Chai
Xiaoyun
Wang
Nan
Cui
Hong
Zhao
Qingjie
Hu
Honggang
Zou
Yan
Sun
Qingyan
Wu
Qiuye
2013
4
4
704
708
Abstract
HTMLPDF
research-article
MedChemComm
2040-2503
Royal Society of Chemistry
Discovery of an HIV integrase inhibitor with an excellent resistance profile
10.1039/c3md00014a
Pryde
David C.
Webster
Rob
Butler
Scott L.
Murray
Edward J.
Whitby
Kevin
Pickford
Chris
Westby
Mike
Palmer
Michael J.
Bull
David J.
Vuong
Hannah
Blakemore
David C.
Stead
Darren
Ashcroft
Christopher
Gardner
Iain
Bru
Claire
Cheung
Wai-Yee
Roberts
Ieuan O.
Morton
Jennifer
Bissell
Richard A.
2013
4
4
709
719
Abstract
HTMLPDF
research-article
MedChemComm
2040-2503
Royal Society of Chemistry
Potent growth inhibitory activity of (±)-platencin towards multi-drug-resistant and extensively drug-resistant <i>Mycobacterium tuberculosis</i>
10.1039/c3md00016h
Moustafa
Gamal A. I.
Nojima
Shoji
Yamano
Yoshi
Aono
Akio
Arai
Masayoshi
Mitarai
Satoshi
Tanaka
Tetsuaki
Yoshimitsu
Takehiko
2013
4
4
720
723
Abstract
HTMLPDF
research-article
MedChemComm
2040-2503
Royal Society of Chemistry
Synthesis and antiplasmodial evaluation of aziridine–(iso)quinoline hybrids and their ring-opening products
10.1039/c3md20377h
Vandekerckhove
Stéphanie
Moor
Sofie De
Segers
Dries
Kock
Carmen de
Smith
Peter J.
Chibale
Kelly
Kimpe
Norbert De
D'hooghe
Matthias
2013
4
4
724
730
Abstract
HTMLPDF
research-article
MedChemComm
2040-2503
Royal Society of Chemistry
Synthesis and biological evaluation of primaquine–chloroquine twin drug: a novel heme-interacting molecule prevents free heme and hydroxyl radical-mediated protein degradation
10.1039/c3md00019b
Pal
Chinmay
Sarkar
Souvik
Mazumder
Somnath
Adhikari
Susanta
Bandyopadhyay
Uday
2013
4
4
731
736
Abstract
HTMLPDF
research-article
MedChemComm
2040-2503
Royal Society of Chemistry
Small organic molecules targeting PCAF bromodomain as potent inhibitors of HIV-1 replication
10.1039/c3md20376j
Wang
Qiang
Wang
Ruirui
Zhang
Baiqun
Zhang
Shuai
Zheng
Yongtang
Wang
Zhiyong
2013
4
4
737
740
Abstract
HTMLPDF
research-article
MedChemComm
2040-2503
Royal Society of Chemistry
5′-Nor carbocyclic nucleosides: unusual nonnucleoside inhibitors of HIV-1 reverse transcriptase
10.1039/c3md00036b
Matyugina
Elena S.
Valuev-Elliston
Vladimir T.
Babkov
Denis A.
Novikov
Mikhail S.
Ivanov
Alexander V.
Kochetkov
Sergey N.
Balzarini
Jan
Seley-Radtke
Katherine L.
Khandazhinskaya
Anastasia L.
2013
4
4
741
748
Abstract
HTMLPDF
research-article
MedChemComm
2040-2503
Royal Society of Chemistry
Benzisothiazolones arrest the cell cycle at the G<sub>2</sub>/M phase and induce apoptosis in HeLa cells
10.1039/c3md00034f
Gopinath
Pushparathinam
Ramalingam
Krishnan
Muraleedharan
Kannoth Manheri
Karunagaran
Devarajan
2013
4
4
749
752
Abstract
HTMLPDF
research-article
MedChemComm
2040-2503
Royal Society of Chemistry
Inside back cover
10.1039/c3md90009F
AuthorAnonymous
2013
4
4
753
754
Abstract
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