Hickinbottom Award 2009 Winner
Awarded for his exploitation of genomics, for the discovery of novel bioactive natural products and his mechanistic studies on enzymes that catalyse key steps in pathogenicity-conferring siderophore biosynthesis.
University of Warwick
About the winner
Greg Challis was awarded a BSc in Chemistry by Imperial College London and a DPhil in Organic Chemistry by the University of Oxford, for research carried out under the supervision of Prof. Sir Jack Baldwin FRS.
After postdoctoral research as a Wellcome Trust International Prize Travelling Research Fellow in the Department of Chemistry at Johns Hopkins University, USA and the Department of Genetics at John Innes Centre, UK, he moved in 2001 to the Department of Chemistry at University of Warwick, where he is currently Professor of Chemical Biology.
His research interests are focused on the chemistry and biology of bioactive natural products. This includes the exploitation of genomics for new natural product discovery, the genetics and mechanistic enzymology of natural product biosynthesis, synthetic biology and mutasynthesis approaches to the generation of novel bioactive natural product derivatives, and elucidation of the biological function of natural products.
His research group pursues a multidisciplinary approach to research in these areas that encompasses chemical synthesis, molecular genetic manipulation, protein chemistry and enzymology, bioinformatics, microbiology and a broad range of analytical chemistry techniques.
Previous research awards include the 2002 Meldola Medal and Prize of the Royal Society of Chemistry and the 2007 Fleming Prize Lecture of the Society of General Microbiology. He was the inaugural recipient of the Wain Medal Lecture of the University of Kent in 2007 for exceptional research at the biology-chemistry interface.
The Challis Group
Department of Chemistry at the University of Warwick
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