Pedler Award 2011 Winner
University of Toronto
Awarded for his discovery of useful new methodology for the construction of carbocycles and heterocyles and application of this in the synthesis of natural products and biologically active compounds. His research uses metal catalysts to selectively form C-C, C-X and C-N bonds in a chemo, stereo- and enantioselective fashion.
About the Winner
Mark Lautens was born in Hamilton, Canada in 1959 and obtained his B.Sc. (Distinction) from the University of Guelph in 1981. Following completion of his Ph.D. in 1985 working with Barry M. Trost (University of Wisconsin-Madison) where he discovered the Pd enyne cyclization and Mo catalyzed allylic alkylations, he studied with David. A. Evans (Harvard University) where he conducted synthetic studies towards bryostatin. He was supported by NSERC Canada throughout his studies. He was appointed as a University Research Fellow/Assistant Professor at the University of Toronto and was promoted to Associate Professor in 1992 and Professor in 1995.
He has held the AstraZeneca Chair in Organic Synthesis since 1998 and in addition is Merck Frosst/NSERC Industrial Research Chair since 2003. He has held visiting Professorships in Paris, Geneva, Marburg, MPI Mülheim and Barcelona and was selected for an Alexander von Humboldt Award in 2009. In addition, he has been selected as an A.P. Sloan Fellow, Eli Lilly Grantee, E.W.R. Steacie Fellow, A.C. Cope Scholar, A. Bader Award, R. Lemieux Award and Fellow of the Royal Society of Canada. His research interests are in the areas of catalysis, asymmetric synthesis, methodology and synthesis.
His most important contributions are in the areas of asymmetric ring opening reactions and other reactions promoted by ring strain. He has recently developed carbohalogenation reactions and domino catalysis processes. He has published 270 articles, reviews and book chapters and given 350 lectures. Outside of work he plays squash, skis and cycles with his family and he enjoys travel, food and wine.
The Lautens Group
University of Toronto, Department of Chemistry
External links will open in a new browser window