Vaccines save millions of lives, but most are only stable when refrigerated. The University of Bath's new technology, ensilication, can make vaccines stable without refrigerators. This means that vaccines could be physically delivered to more people around the world, so extra 2 million people could be saved every year from vaccine-preventable diseases.
MicroCoatTM opens up industrial-scale polymer coating of drug-containing microparticles. Manufacturing particles suitable for inclusion in liquid medicines, that control drug release or mask drug taste is highly challenging due to their small size. MicroCoatTM innovative particle engineering approach prevents particle agglomeration during fluidised bed coating and achieves industrially advantageous yields.
Many medicines are manufactured as crystalline solids for inclusion in tablets and capsules, but discovering the correct crystalline form is often difficult. Indicatrix's nanodroplet crystallisation technology utilises liquid-handling robotics to enable rapid, in-depth experimental space exploration. Thus they provide answers to the most challenging of crystallisation problems, accelerating drug development.
Oxford HighQ have developed an instrument using optical microcavities, that can characterise novel solutions by measuring loading of drug delivery nanoparticles at single particle level, a key parameter for advanced therapies.
University of Cambridge
Minimally-invasive conductive polymer implant for pain management
The University of Cambridge have developed a spinal cord stimulator using thin-film, shape adaptive electronics and conductive polymers. This device can be introduced to a patient using minimally-invasive surgical techniques but offers the efficacy of large area conventional stimulators. The device has applications in pain management, rehabilitation and movement disorders.
Many drugs suffer from poor localisation and are rapidly cleared from the body. Vector develops porous nanoparticles called MOFs as a drug delivery platform. These materials carry large quantities of a wide range of therapeutics and are readily tuned for targeted delivery and controlled release.
To have the endorsement of the Royal Society of Chemistry for the stage we’re at is phenomenal, and gives us real impetus to speak with investors and stakeholders and demonstrate our enthusiasm and expertise in this area
Viridi CO2 have engineered heterogeneous, high-surface area, porous catalysts capable of transforming CO2 into polyurethane feedstock materials. Utilising lower temperatures and pressure than those currently available, this process provides a route to reduced petrochemical reliance by harnessing a synergetic relationship between adjacent active sites to insert CO2 with high efficiency.
Gas Recovery and Recycle Limited have developed a point of use ethylene oxide, EtO, generator that utilises green bioethanol and generate quantities of EtO in the correct gas mixture to be used to sterilize medial devices and allow the safe re-use of PPE. EtO is the most effective low temperature sterilisation agent there is.
Globally, sewage treatment releases ~4%GHG emissions. Greenskill's negative emission process captures CO2, produces zero sewage sludge, eliminates nitrous oxide and volatile emissions and removes nutrients and emerging contaminants - in a single stage. The process employs proprietary microalgae and industrial scale photobioreactor technology, harvested microalgae are monetised as a soil conditioner and fertiliser.
Mission Zero Technologies have developed a decentralized and energy-efficient technology for removing CO2 from air and delivering it as a product. Their technology employs unique catalysts for accelerating CO2 capture and release. Deployed in an innovative, low-cost and scalable product design, this will enable CO2 emitters/consumers to fulfill carbon net-zero ambitions.
Riptron Limited have developed a miniaturised suspended graphene array gas sensor for real-time air quality monitoring. The sensor's ability to integrate with consumer electronics will provide a cost-effective technological solution for real-time/high-resolution selective detection of low concentrations of toxic atmospheric pollutants and to help the world to breath quality air.
University of A Coruna have developed a family of hybrid organic-inorganic materials that can be used as safe and eco-friendly solid refrigerants,known as barocaloric hybrid materials. These materials exhibit large thermal changes under the application of low pressures and can be chemically engineered to be adaptable to different operating conditions.
The COVID-19 pandemic has really thrown into relief lots of issues that we face with food security and meat production, and with this life changing opportunity for our start up, and the support and confidence it has given us, we now have a real chance to make a difference with our work
Hoxton Farms are using mathematical modelling and machine learning to build a novel and scalable technology for expanding and differentiating adult stem cells to make cultivated meat products (meat grown from animal cells in labs).
BettaSensing will revolutionize screening methods currently used in the food market. Their technology is based on a combination of colorimetric sensors. As a response to different environments e.g. different beverages, their colour changes. The overall change is then analyzed using advanced AI to create unique 'fingerprints' for each product.
Glaia have a revolutionary product to boost crop yields, their patent-pending technology, is based on a water-soluble sugar-based material that unlocks the current bottleneck in agricultural production: the inefficiency of crops at utilising sunlight. Glaia's technology enhance crop's photosynthetic efficiency improving their performance which translates in yield increases over 20%.
From food waste to fashion - we transform the fish industry waste into a collagen-based material that replicates genuine leather. As leather is 90% collagen, this material replicates the authentic feel of leather and significantly reduce water consumption, carbon footprint, and off-cut waste generated in the leather manufacturing process.
Mitocholine™ is a novel chemical composition of natural metabolites with health claims. The aspiration behind Mitocholine™, if consumed regularly in the diet, is that it will counteract the development of metabolic syndrome and impede the onset of dementia. The patent protection is based on the synergy of Mitocholine's™ chemical compounds.
Based on the award winning research of founder Dr. Conor Kerley, PhytaphixTM, have developed a specific combination formula of natural ingredients which can increase nitric oxide (Nobel Prize was awarded for discovery of nitric oxide) and increase blood vessel size. This allows more blood to flow, decreasing high blood pressure, which affects over 1 billion people, as well as increasing sports performance. The formula is available in capsule or powdered form for ultra convenience.
Chromosol Ltd have developed an approach to building optical amplifiers and lasers directly onto silicon chips. This will allow for the future integration of electronic and optical communications systems resulting in greater data transfer rates using reduced power consumption.
ATLANT 3D Nanosystems have created the most accurate and versatile atomic layer 3D printing technology for prototyping and manufacturing of micro and nanodevices. We provide novel, smart and cost-efficient atomically precise additive manufacturing in micro/nanodevices fabrication, such as MEMS & Sensors, RF devices, photonic/optics, with design flexibility and material versatility.
Inspired by nature, the University of Cambridge have developed effect pigments prepared from a single organic and renewable component extracted from wood: cellulose nanocrystals. Obtained via self-assembly, these pigments offer the most sustainable alternative to all existing products, including microplastic, partially biodegradable glitter, and unethically sourced mica-based pigments.
Synple Chem's automated capsule-based synthesiser works analogously to a capsule coffee maker. Requiring no optimisation, it is ideally suited to the needs of discovery chemistry. Following the addition of the starting material and a commercially available reagent capsule, the product is generated, isolated and purified at the touch of a single button.
Plant Protein is the next generation of bio-based material, and a replacement for single-use plastics. Xampla is focusing initially on applications in microplastics, such as microcapsules for personal and home care, where we can design high performance capsules that degrade naturally in the environment at end of life.