Flash chromatography

Definition: A type of rapid preparative column chromatography where 0.1--10 g of sample mixture is separated in less than 15 min by using pressurised gas to drive the mobile phase through the column.

ID: CMO:0002582

Synonyms:

More about the RSC Chemical Methods Ontology (CMO)

Articles referencing this term

Synthesis and biodistribution of [^99mTc]-N-[4-nitro-3-trifluoromethyl-phenyl] cyclopentadienyltricarbonyltechnetium carboxamide, a nonsteroidal antiandrogen flutamide derivative
Tesnim Dallagi, Siden Top, Stéphane Masi, Gérard Jaouen and Mouldi Saidi, Metallomics, 2010 , 2 , 289
DOI: 10.1039/b925224j

Micelles with surface conjugated RGD peptide and crosslinked polyurea core via RAFT polymerization
Hien T. T. Duong, T. L. Uyen Nguyen and Martina H. Stenzel, Polym. Chem., 2010 , 1 , 171
DOI: 10.1039/b9py00210c

Towards the synthesis of a Yersinia pestis cell wall polysaccharide: enantioselective synthesis of an l-glycero-d-manno-heptose building block
Takafumi Ohara, Alexander Adibekian, Davide Esposito, Pierre Stallforth and Peter H. Seeberger, Chem. Commun., 2010 , 46 , 4106
DOI: 10.1039/c000784f

Efficient one-pot synthesis of substituted pyridines through multicomponent reaction
Xin Xin, Yan Wang, Santosh Kumar, Xu Liu, Yingjie Lin and Dewen Dong, Org. Biomol. Chem., 2010 , 8 , 3078
DOI: 10.1039/c001117g

Chimeric microtubule disruptors
Mathew P. Leese, Fabrice Jourdan, Meriel R. Kimberley, Gyles E. Cozier, Nethaji Thiyagarajan, Chloe Stengel, Sandra Regis-Lydi, Paul A. Foster, Simon P. Newman, K. Ravi Acharya, Eric Ferrandis, Atul Purohit, Michael J. Reed and Barry V. L. Potter, Chem. Commun., 2010 , 46 , 2907
DOI: 10.1039/c002558e

Enantioselective total synthesis of plakotenin, a cytotoxic metabolite from Plakortis sp
Stephanie Arzt, Emmanuel Bourcet, Thierry Muller and Stefan Bräse, Org. Biomol. Chem., 2010 , 8 , 3300
DOI: 10.1039/c004199h

Synthesis of naturally occurring naphthoquinone epoxides and application in the synthesis of β-lapachone
Sven Claessens, Pascal Habonimana and Norbert De Kimpe, Org. Biomol. Chem., 2010 , 8 , 3790
DOI: 10.1039/c004580b

Syntheses, X-ray crystal structures and reactivity of fluorenylidene- and dibenzosuberenylidene-allenes: convenient precursors to dispirotetracenes, di-indenotetracenes and 2-phenyl-11bH-dibenz[c d,h]azulene
Emilie V. Banide, Crystal O'Connor, Natasha Fortune, Yannick Ortin, Sandra Milosevic, Helge Müller-Bunz and Michael J. McGlinchey, Org. Biomol. Chem., 2010 , 8 , 3997
DOI: 10.1039/c004868b

Reaction of N-acetylneuraminic acid derivatives with perfluorinated anhydrides: a short access to N-perfluoracylated glycals with antiviral properties
Paola Rota, Pietro Allevi, Roberto Mattina and Mario Anastasia, Org. Biomol. Chem., 2010 , 8 , 3771
DOI: 10.1039/c004938g

A convergent approach to (R)-Tiagabine by a regio- and stereocontrolled hydroiodination of alkynes
Giuseppe Bartoli, Roberto Cipolletti, Giustino Di Antonio, Riccardo Giovannini, Silvia Lanari, Mauro Marcolini and Enrico Marcantoni, Org. Biomol. Chem., 2010 , 8 , 3509
DOI: 10.1039/c005042c

Synthesis of functionalized resorcinols by rhodium-catalyzed [5+1] cycloaddition reaction of 3-acyloxy-1,4-enynes with CO
Célia Brancour, Takahide Fukuyama, Yuko Ohta, Ilhyong Ryu, Anne-Lise Dhimane, Louis Fensterbank and Max Malacria, Chem. Commun., 2010 , 46 , 5470
DOI: 10.1039/c0cc00747a

Solvent-free microwave-assisted multi-component reaction for preparation of 2-amino-1-aryl-2-(cyclohex-1-enyl)ethanones as precursors of pseudoephedrine analogues
Li-Jian Ma and Tsutomu Inokuchi, Chem. Commun., 2010 , 46 , 7037
DOI: 10.1039/c0cc00859a

Magnetically separable nanoferrite-anchored glutathione: aqueous homocoupling of arylboronic acids under microwave irradiation
Rafael Luque, Babita Baruwati and Rajender S. Varma, Green Chem., 2010 , 12 , 1540
DOI: 10.1039/c0gc00083c

Synthesis and NMDA receptor affinity of dexoxadrol analogues with modifications in position 4 of the piperidine ring
Ashutosh Banerjee, Roland Fröhlich, Dirk Schepmann and Bernhard Wünsch, Med. Chem. Commun., 2010 , 1 , 87
DOI: 10.1039/c0md00017e

Design, synthesis, and structure–activity relationships of indole-3-carboxamides as novel water soluble cannabinoid CB1 receptor agonists
Julia M. Adam, Jim Cairns, Wilson Caulfield, Phillip Cowley, Iain Cumming, Morag Easson, Darren Edwards, Morag Ferguson, Richard Goodwin, Fiona Jeremiah, Takao Kiyoi, Ashvin Mistry, Elizabeth Moir, Richard Morphy, Jason Tierney, Mark York, James Baker, Jean E. Cottney, Andrea K. Houghton, Paul J. Westwood and Glenn Walker, Med. Chem. Commun., 2010 , 1 , 54
DOI: 10.1039/c0md00022a

Synthesis, modeling, and crystallographic study of 3,4-disubstituted-1,2,5-oxadiazoles and evaluation of their ability to decrease STAT3 activity
Dae-Seop Shin, Daniela Masciocchi, Arianna Gelain, Stefania Villa, Daniela Barlocco, Fiorella Meneghetti, Alessandro Pedretti, Young-Min Han, Dong Cho Han, Byoung-Mog Kwon, Laura Legnani and Lucio Toma, Med. Chem. Commun., 2010 , 1 , 156
DOI: 10.1039/c0md00057d

Organosilicon-mediated total synthesis of the triquinane sesquiterpenes (±)-β-isocomene and (±)-isocomene
Arndt W. Schmidt, Thomas Olpp, Elke Baum, Tina Stiffel and Hans-Joachim Knölker, Org. Biomol. Chem., 2010 , 8 , 4562
DOI: 10.1039/c0ob00051e

Asymmetric synthesis of proline-based conformationally constrained tryptophan mimetic
Pierre-Olivier Delaye, Jean-Luc Vasse and Jan Szymoniak, Org. Biomol. Chem., 2010 , 8 , 3635
DOI: 10.1039/c0ob00118j

Synthesis of 1,2-annulated and 1,2-unsubstituted pyrrolo[2,1,5-de]quinolizin-5-ones (cycl[3.3.2]azin-5-ones) via [3+2] cycloadditions of 1-oxoquinolizinium ylides with cyclic alkenes
Yun Liu, Hua-You Hu, Yan Zhang, Hong-Wen Hu and Jian-Hua Xu, Org. Biomol. Chem., 2010 , 8 , 4921
DOI: 10.1039/c0ob00299b

Stereoselective synthesis of enynones via base-catalyzed isomerization of 1,5-disubstituted-2,4-pentadiynyl silyl ethers or their alcohol derivatives
Jingjin Chen, Guoqin Fan and Yuanhong Liu, Org. Biomol. Chem., 2010 , 8 , 4806
DOI: 10.1039/c0ob00344a

Access to phosphoproteins and glycoproteins through semi-synthesis, Native Chemical Ligation and N→S acyl transfer
Jinit Masania, Jiejin Li, Stephen J. Smerdon and Derek Macmillan, Org. Biomol. Chem., 2010 , 8 , 5113
DOI: 10.1039/c0ob00363h

Synthetic studies on the mycolactone core
Kwang-Seuk Ko, Matthew D. Alexander, Shaun D. Fontaine, James E. Biggs-Houck, James J. La Clair and Michael D. Burkart, Org. Biomol. Chem., 2010 , 8 , 5159
DOI: 10.1039/c0ob00540a

Mutanobactin A from the human oral pathogen Streptococcus mutans is a cross-kingdom regulator of the yeast-mycelium transition
P. Matthew Joyner, Jinman Liu, Zhijun Zhang, Justin Merritt, Fengxia Qi and Robert H. Cichewicz, Org. Biomol. Chem., 2010 , 8 , 5486
DOI: 10.1039/c0ob00579g

Dissecting tunicamycin biosynthesis by genome mining: cloning and heterologous expression of a minimal gene cluster
Filip J. Wyszynski, Andrew R. Hesketh, Mervyn J. Bibb and Benjamin G. Davis, Chem. Sci., 2010 , 1 , 581
DOI: 10.1039/c0sc00325e