Baeyer-Villiger oxidation

Definition: A reaction of a ketone to give an ester, in which an alkyl, benzyl or phenyl group migrates from one of the alpha-carbon centres to an adjacent oxygen, displacing an oxygen-based leaving group; the result is a formal insertion of an oxygen atom. The reaction also works with aldehydes, giving the corresponding carboxylic acid. The term \"Baeyer-Villiger rearrangement\" may occasionally be used in a mechanistic sense to refer specificially to the actual rearrangement step.

ID: RXNO:0000031


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