Gabriel synthesis

Definition: The reaction of primary alkyl halides with sodium or potassium phthalimide, followed by hydrolysis, to give the corresponding primary amine.

ID: RXNO:0000103

More about the RSC Name Reaction Ontology (RXNO)

Articles referencing this term

Synthesis of aminomethylated 4-fluoropiperidines and 3-fluoropyrrolidines
Guido Verniest, Karel Piron, Eva Van Hende, Jan Willem Thuring, Gregor Macdonald, Frederik Deroose and Norbert De Kimpe, Org. Biomol. Chem., 2010 , 8 , 2509
DOI: 10.1039/c003380d