Finkelstein reaction

Definition: The conversion of an alkyl chloride, alkyl bromide or alkyl sulfonate ester to an alkyl iodide by SN2 substitution. The reaction relies upon the equilibrium being pushed to completion by the precipitation.

ID: RXNO:0000155

More about the RSC Name Reaction Ontology (RXNO)

Articles referencing this term

Efforts toward elucidating Thalidomide’s molecular target: an expedient synthesis of the first Thalidomide biotin analogue
Scott G. Stewart, Carlos J. Braun, Marta E. Polomska, Mahdad Karimi, Lawrence J. Abraham and Keith A. Stubbs, Org. Biomol. Chem., 2010 , 8 , 4059
DOI: 10.1039/c0ob00060d

Synthesis of the core ring system of the stemona alkaloids by cascade condensation, cyclization, intramolecular cycloaddition
Adam. J. M. Burrell, Luke Watson, Nathaniel G. Martin, Niall Oram and Iain Coldham, Org. Biomol. Chem., 2010 , 8 , 4530
DOI: 10.1039/c0ob00408a

Diamine ligands in copper-catalyzed reactions
David S. Surry and Stephen L. Buchwald, Chem. Sci., 2010 , 1 , 13
DOI: 10.1039/c0sc00107d