{"text_format":"2","workbook":"xls","n_sheets":2,"sheets":["GO","Hallmarks"],"not_rendered":{"charts":0,"images":0,"macros":0,"external_links":1,"defined_names":1,"comments":0,"pivot_tables":0},"unopened":[],"bounds":{"document_bytes":16777216,"sheet_cells":100000,"run_cost":"one","rows_first":2000,"rows_last":500,"rows_between":2000,"halvings":0,"cell_chars":16384,"cell_head_chars":4096},"cells_cut":0,"cells_raw":0,"read":"whole","date_system":"1900","formulas":"cached_only"}

{"sheet":"GO","index":0,"n_rows":108,"n_cols":8,"rows_kept":108,"cut":false,"hidden":false,"merged":[],"flags":["formulas_cached_only"]}
["Geneset","Ontology","GO_ID","Name","Hit Genes","The number of Hit Genes","Pvalue","FDR"]
["gain ceRNAs","GO_Process","GO:0000278","mitotic cell cycle","332,890,891,898,990,993,1026,1063,1869,1871,3619,4172,4175,4331,4605,5347,6241,6502,7153,7298,7846,8317,9493,9793,9837,11190,55143,55388,55920,81620,81930,84296,146909,286826,387103,",35,0,0]
["gain ceRNAs","GO_Process","GO:0007155","cell adhesion","705,920,976,1303,1829,1901,1947,2621,3383,3684,4921,5581,6387,6403,6404,7041,7094,8038,8406,8828,9473,9891,10085,10174,10979,22915,29780,50937,55698,57091,57608,64065,140885,",33,0,1.4e-05]
["gain ceRNAs","GO_Process","GO:0045736","negative regulation of cyclin-dependent protein serine/threonine kinase activity","1026,5347,7023,7026,7128,8850,26524,",7,0,2.7e-05]
["gain ceRNAs","GO_Process","GO:0000082","G1/S transition of mitotic cell cycle","891,898,990,993,1026,1869,3400,4172,4175,4331,6241,6502,7298,8317,26524,55388,81620,",17,1e-06,5.9e-05]
["gain ceRNAs","GO_Process","GO:0000086","G2/M transition of mitotic cell cycle","332,890,891,993,1026,1111,1663,4331,5347,6502,7846,8493,9793,11190,",14,3e-06,0.000196]
["gain ceRNAs","GO_Process","GO:0006260","DNA replication","990,993,1063,1111,4172,4175,6241,7083,7153,7298,8317,9768,55388,81620,286826,",15,7e-06,0.000262]
["gain ceRNAs","GO_Process","GO:0008285","negative regulation of cell proliferation","104,990,1026,2113,2247,3159,4601,4830,5376,6595,7023,7041,7077,8493,8850,9314,10252,10608,11095,25959,27102,27244,51621,83595,144455,",25,8e-06,0.000262]
["gain ceRNAs","GO_Process","GO:0050900","leukocyte migration","857,1277,2621,3383,3684,4478,6403,6404,6693,7056,51744,58494,140885,",13,6e-06,0.000262]
["gain ceRNAs","GO_Process","GO:0051301","cell division","332,890,891,898,990,993,1063,3832,5581,6867,7846,8317,9793,10982,22974,26524,55143,55920,64151,81610,146909,152185,387103,",23,6e-06,0.000262]
["gain ceRNAs","GO_Process","GO:0071398","cellular response to fatty acid","891,1869,4830,55022,",4,8e-06,0.000262]
["gain ceRNAs","GO_Process","GO:0045893","positive regulation of transcription, DNA-dependent","672,860,890,898,1277,1316,1389,1869,1871,1879,1959,2113,2247,2296,3159,3586,3608,4286,6595,6925,7023,7026,7041,9314,23090,30009,64321,64641,81606,83595,84662,",31,9e-06,0.000267]
["gain ceRNAs","GO_Process","GO:0051726","regulation of cell cycle","104,2247,3726,4616,5347,5788,6502,9768,10460,63979,",10,1.2e-05,0.00032]
["gain ceRNAs","GO_Process","GO:0008283","cell proliferation","678,863,975,993,1063,1736,1869,2012,2013,2549,2621,3638,4288,4331,5347,6502,6935,9787,10982,22974,51776,55790,79733,",23,3.3e-05,0.000753]
["gain ceRNAs","GO_Process","GO:0045944","positive regulation of transcription from RNA polymerase II promoter","154,672,863,1390,1742,1869,1901,1959,2034,2113,2247,2296,2627,3202,3400,3586,3726,4094,4286,4331,5591,6595,6925,7153,7291,8850,9314,9935,50937,51621,51804,55022,64321,79733,80312,84662,133522,144455,",38,3.2e-05,0.000753]
["gain ceRNAs","GO_Process","GO:0007067","mitosis","332,890,990,993,3832,3835,5347,10982,22974,26524,54443,55165,55872,81610,146909,387103,",16,5.9e-05,0.001248]
["gain ceRNAs","GO_Process","GO:0007596","blood coagulation","409,857,966,1277,2621,2627,3684,3708,3832,3835,5138,5581,5739,6403,6404,6693,7056,7094,8654,9493,10019,22915,29127,30846,51744,58494,81930,140885,",28,6.4e-05,0.001269]
["gain ceRNAs","GO_Process","GO:0031503","protein complex localization","332,1789,57576,",3,7.7e-05,0.001371]
["gain ceRNAs","GO_Process","GO:0046813","virion attachment, binding of host cell surface receptor","975,2621,3383,",3,7.7e-05,0.001371]
["gain ceRNAs","GO_Process","GO:0032715","negative regulation of interleukin-6 production","409,2621,3071,3586,7128,",5,9.1e-05,0.001533]
["gain ceRNAs","GO_Process","GO:0000085","G2 phase of mitotic cell cycle","1063,1869,1871,3838,",4,9.8e-05,0.001563]
["gain ceRNAs","GO_Process","GO:0032720","negative regulation of tumor necrosis factor production","409,2621,3586,7128,7291,27202,",6,0.000107,0.001625]
["gain ceRNAs","GO_Process","GO:0031100","organ regeneration","728,1026,2621,3936,4288,7049,7298,",7,0.000121,0.001761]
["gain ceRNAs","GO_Process","GO:0006955","immune response","728,920,976,1240,1520,2113,3111,3274,3554,3608,5724,5734,6387,6693,6935,7049,7133,8530,8742,9173,25939,80380,",22,0.000139,0.001928]
["gain ceRNAs","GO_Process","GO:0032695","negative regulation of interleukin-12 production","409,1240,3586,4210,",4,0.000151,0.002003]
["gain ceRNAs","GO_Process","GO:0000083","regulation of transcription involved in G1/S phase of mitotic cell cycle","898,990,6241,7298,81620,",5,0.000158,0.002016]
["gain ceRNAs","GO_Process","GO:0000910","cytokinesis","332,3619,5347,9493,9700,29127,54443,55165,",8,0.00018,0.002211]
["gain ceRNAs","GO_Process","GO:0000087","M phase of mitotic cell cycle","332,1063,3619,5347,9493,9787,9793,55143,55920,81930,",10,0.000192,0.002263]
["gain ceRNAs","GO_Process","GO:2000134","negative regulation of G1/S transition of mitotic cell cycle","2273,25959,91607,144455,",4,0.000221,0.002521]
["gain ceRNAs","GO_Process","GO:0000084","S phase of mitotic cell cycle","990,993,1026,1663,4172,4175,4331,6502,9837,81620,84296,",11,0.000268,0.002953]
["gain ceRNAs","GO_Process","GO:0071777","positive regulation of cell cycle cytokinesis","990,5581,9493,29127,",4,0.000313,0.003326]
["gain ceRNAs","GO_Process","GO:0045892","negative regulation of transcription, DNA-dependent","332,672,860,1063,1869,2247,2621,2627,3159,3400,6595,6935,7023,7026,9208,9314,23090,23741,27122,55635,56849,83595,84662,93166,133522,",25,0.000325,0.003342]
["gain ceRNAs","GO_Process","GO:0032691","negative regulation of interleukin-1 beta production","409,4210,7128,",3,0.000371,0.003505]
["gain ceRNAs","GO_Process","GO:0033261","regulation of S phase","1111,5788,8317,",3,0.000371,0.003505]
["gain ceRNAs","GO_Process","GO:0035690","cellular response to drug","969,2621,4830,5138,5141,5142,",6,0.000374,0.003505]
["gain ceRNAs","GO_Process","GO:0007018","microtubule-based movement","3832,3835,9493,9928,29127,57576,81930,146909,",8,0.000439,0.003889]
["gain ceRNAs","GO_Process","GO:0030199","collagen fibril organization","1277,1281,1303,2296,4921,50509,",6,0.000436,0.003889]
["gain ceRNAs","GO_Process","GO:0000236","mitotic prometaphase","332,891,1063,3619,5347,9793,55143,55920,81930,",9,0.000484,0.004171]
["gain ceRNAs","GO_Process","GO:0000079","regulation of cyclin-dependent protein serine/threonine kinase activity","890,891,898,990,993,1026,4331,",7,0.000537,0.004508]
["gain ceRNAs","GO_Process","GO:0007159","leukocyte cell-cell adhesion","3383,3684,4478,6403,83706,",5,0.000586,0.004795]
["gain ceRNAs","GO_Process","GO:0000122","negative regulation of transcription from RNA polymerase II promoter","857,1789,1869,1910,2627,3400,4094,4601,5138,5347,6595,6911,6925,6935,7026,7291,9314,10174,10608,23429,23741,25959,64321,79733,84662,144455,255877,",27,0.000692,0.005344]
["gain ceRNAs","GO_Process","GO:0018146","keratan sulfate biosynthetic process","2331,4969,5549,6482,8702,",5,0.000704,0.005344]
["gain ceRNAs","GO_Process","GO:0042130","negative regulation of T cell proliferation","3586,6693,8654,11326,80380,",5,0.000704,0.005344]
["gain ceRNAs","GO_Process","GO:0007399","nervous system development","1742,1808,1910,2247,3984,4681,5026,5050,6595,8787,23090,28969,51232,55790,79026,84662,91851,223117,",18,0.000745,0.005529]
["gain ceRNAs","GO_Process","GO:0045647","negative regulation of erythrocyte differentiation","3202,9935,51621,",3,0.000999,0.007241]
["gain ceRNAs","GO_Process","GO:0001570","vasculogenesis","857,2296,3726,9444,10052,57493,64321,",7,0.001034,0.00733]
["gain ceRNAs","GO_Process","GO:0042102","positive regulation of T cell proliferation","966,1947,3071,5788,6693,80380,",6,0.001128,0.007656]
["gain ceRNAs","GO_Process","GO:0071456","cellular response to hypoxia","891,1869,2034,2627,3383,5366,5581,7291,",8,0.001119,0.007656]
["gain ceRNAs","GO_Process","GO:0031648","protein destabilization","5347,5591,6622,64321,",4,0.00149,0.009702]
["gain ceRNAs","GO_Process","GO:0071310","cellular response to organic substance","968,1959,7077,7078,",4,0.00149,0.009702]
["gain ceRNAs","GO_Process","GO:0001933","negative regulation of protein phosphorylation","891,5621,6622,8613,55022,",5,0.00157,0.009823]
["gain ceRNAs","GO_Process","GO:0042339","keratan sulfate metabolic process","2331,4969,5549,6482,8702,",5,0.00157,0.009823]
["gain ceRNAs","GO_Process","GO:0007059","chromosome segregation","332,672,1063,3619,6732,7153,387103,",7,0.001677,0.010288]
["gain ceRNAs","GO_Process","GO:0008354","germ cell migration","2296,6387,8613,",3,0.002055,0.011921]
["gain ceRNAs","GO_Process","GO:0009100","glycoprotein metabolic process","30815,256435,338596,",3,0.002055,0.011921]
["gain ceRNAs","GO_Process","GO:0032703","negative regulation of interleukin-2 production","5621,7128,11326,",3,0.002055,0.011921]
["gain ceRNAs","GO_Process","GO:0050728","negative regulation of inflammatory response","4210,5734,7128,7133,9314,10203,",6,0.002454,0.013981]
["gain ceRNAs","GO_Process","GO:0007050","cell cycle arrest","323,580,1026,2619,2621,4436,5621,8850,27244,51776,",10,0.002694,0.014975]
["gain ceRNAs","GO_Process","GO:0060707","trophoblast giant cell differentiation","7026,79733,144455,",3,0.00277,0.014975]
["gain ceRNAs","GO_Process","GO:0090307","spindle assembly involved in mitosis","3832,4605,152185,",3,0.00277,0.014975]
["gain ceRNAs","GO_Process","GO:0009314","response to radiation","993,1281,8493,51776,",4,0.003125,0.016345]
["gain ceRNAs","GO_Process","GO:0031397","negative regulation of protein ubiquitination","409,857,7128,9683,",4,0.003125,0.016345]
["gain ceRNAs","GO_Process","GO:0001568","blood vessel development","1277,1281,2889,7049,8613,",5,0.003427,0.017353]
["gain ceRNAs","GO_Process","GO:0051591","response to cAMP","1036,1277,3726,4830,133522,",5,0.003427,0.017353]
["gain ceRNAs","GO_Process","GO:0019886","antigen processing and presentation of exogenous peptide antigen via MHC class II","1520,3111,3832,3835,8905,9493,29127,81930,",8,0.003484,0.017367]
["gain ceRNAs","GO_Process","GO:0042340","keratan sulfate catabolic process","2331,4969,5549,",3,0.003619,0.017492]
["gain ceRNAs","GO_Process","GO:0042994","cytoplasmic sequestering of transcription factor","4601,4796,10460,",3,0.003619,0.017492]
["gain ceRNAs","GO_Process","GO:0000075","cell cycle checkpoint","891,990,993,1026,1111,4172,4175,8317,51776,55388,",10,0.003942,0.018005]
["gain ceRNAs","GO_Process","GO:0000080","G1 phase of mitotic cell cycle","1026,1869,1871,4331,6502,",5,0.003845,0.018005]
["gain ceRNAs","GO_Process","GO:0048661","positive regulation of smooth muscle cell proliferation","1901,4331,6502,7052,10203,",5,0.003845,0.018005]
["gain ceRNAs","GO_Process","GO:0071260","cellular response to mechanical stimulus","477,1111,1277,5138,5734,51311,",6,0.003951,0.018005]
["gain ceRNAs","GO_Process","GO:0045860","positive regulation of protein kinase activity","920,2621,3071,4921,5788,",5,0.004298,0.019044]
["gain ceRNAs","GO_Process","GO:0051209","release of sequestered calcium ion into cytosol","2247,3708,5581,5788,",4,0.004278,0.019044]
["gain ceRNAs","GO_Process","GO:0046688","response to copper ion","3383,5621,7083,",3,0.004611,0.020149]
["gain ceRNAs","GO_Process","GO:0030217","T cell differentiation","860,920,5788,30009,",4,0.00495,0.020506]
["gain ceRNAs","GO_Process","GO:0032689","negative regulation of interferon-gamma production","2621,3586,5621,9173,",4,0.00495,0.020506]
["gain ceRNAs","GO_Process","GO:0048662","negative regulation of smooth muscle cell proliferation","4969,5739,7128,9314,",4,0.00495,0.020506]
["gain ceRNAs","GO_Process","GO:0048701","embryonic cranial skeleton morphogenesis","860,2619,7291,51804,",4,0.00495,0.020506]
["gain ceRNAs","GO_Process","GO:0006198","cAMP catabolic process","5138,5141,5142,",3,0.005752,0.023225]
["gain ceRNAs","GO_Process","GO:0071333","cellular response to glucose stimulus","2621,3383,3956,4830,",4,0.005688,0.023225]
["gain ceRNAs","GO_Process","GO:0000077","DNA damage checkpoint","1111,1869,25896,51776,",4,0.006497,0.025905]
["gain ceRNAs","GO_Process","GO:0034097","response to cytokine stimulus","1281,3726,7077,7298,58191,",5,0.007148,0.028152]
["gain ceRNAs","GO_Process","GO:0031623","receptor internalization","409,2890,6622,10203,",4,0.007378,0.028701]
["gain ceRNAs","GO_Process","GO:0071222","cellular response to lipopolysaccharide","1910,3383,3586,5142,7128,7133,",6,0.007616,0.029271]
["gain ceRNAs","GO_Process","GO:0030154","cell differentiation","1063,1389,1390,2054,2273,4616,8742,10019,23090,23741,25932,28969,51776,55723,79723,83478,84662,91851,223117,",19,0.007726,0.029342]
["gain ceRNAs","GO_Process","GO:0000186","activation of MAPKK activity","2247,2889,4215,4616,51776,",5,0.007846,0.029444]
["gain ceRNAs","GO_Process","GO:0045070","positive regulation of viral genome replication","104,6732,7153,",3,0.0085,0.031168]
["gain ceRNAs","GO_Process","GO:0045930","negative regulation of mitotic cell cycle","2296,2619,7077,",3,0.0085,0.031168]
["gain ceRNAs","GO_Process","GO:0006271","DNA strand elongation involved in DNA replication","4172,4175,9837,84296,",4,0.009368,0.033958]
["gain ceRNAs","GO_Process","GO:0050731","positive regulation of peptidyl-tyrosine phosphorylation","409,920,975,2252,8613,30844,",6,0.009476,0.033964]
["gain ceRNAs","GO_Process","GO:0007166","cell surface receptor signaling pathway","154,920,966,976,1910,3554,3707,5788,6693,11024,",10,0.009695,0.034362]
["gain ceRNAs","GO_Process","GO:0030866","cortical actin cytoskeleton organization","3071,7094,30846,",3,0.010117,0.035466]
["gain ceRNAs","GO_Process","GO:0006461","protein complex assembly","891,1047,1742,3071,3159,4286,4331,7023,",8,0.010625,0.03684]
["gain ceRNAs","GO_Process","GO:0001503","ossification","860,2296,4921,7291,91851,133522,",6,0.010883,0.037329]
["gain ceRNAs","GO_Process","GO:0006935","chemotaxis","728,1240,2247,5724,6387,6693,27202,58191,",8,0.011757,0.039898]
["gain ceRNAs","GO_Process","GO:0001938","positive regulation of endothelial cell proliferation","659,858,2247,8742,8828,",5,0.012049,0.040458]
["gain ceRNAs","GO_Process","GO:0001974","blood vessel remodeling","659,2034,2296,7052,",4,0.012958,0.04267]
["gain ceRNAs","GO_Process","GO:0030308","negative regulation of cell growth","323,659,1026,2247,2273,2619,6595,64321,",8,0.012975,0.04267]
["gain ceRNAs","GO_Process","GO:0042493","response to drug","205,891,1026,1063,1808,2627,3071,3383,3586,3726,3956,6622,7077,7298,",14,0.013171,0.042873]
["gain ceRNAs","GO_Process","GO:0060045","positive regulation of cardiac muscle cell proliferation","891,2247,2627,",3,0.013852,0.044634]
["gain ceRNAs","GO_Process","GO:0001649","osteoblast differentiation","860,1277,3726,7291,63979,",5,0.014089,0.044943]
["gain ceRNAs","GO_Process","GO:0002040","sprouting angiogenesis","25960,79733,144455,",3,0.015975,0.04996]
["gain ceRNAs","GO_Process","GO:0045907","positive regulation of vasoconstriction","857,3274,3383,",3,0.015975,0.04996]
["loss ceRNAs","GO_Process","GO:0000278","mitotic cell cycle","890,1030,1763,1871,1875,4172,4331,5347,5558,6502,7283,8317,9134,9493,11116,11190,54908,57122,64105,81930,84515,91687,286826,",23,1.1e-05,0.002706]
["loss ceRNAs","GO_Process","GO:0000080","G1 phase of mitotic cell cycle","1030,1871,1875,4303,4331,6502,",6,0.000464,0.033278]
["loss ceRNAs","GO_Process","GO:0000087","M phase of mitotic cell cycle","4192,5347,9493,9585,54908,57122,64105,81930,91687,",9,0.000633,0.033278]
["loss ceRNAs","GO_Process","GO:0007528","neuromuscular junction development","785,1287,2064,2263,10497,",5,0.000688,0.033278]
["loss ceRNAs","GO_Process","GO:0050873","brown fat cell differentiation","3914,5743,6517,30001,51316,",5,0.000688,0.033278]

{"sheet":"Hallmarks","index":1,"n_rows":13,"n_cols":5,"rows_kept":13,"cut":false,"hidden":false,"merged":[],"flags":["formulas_cached_only"]}
["Geneset","Ontology","Name","The number of Hit Genes","Pvalue"]
["gain ceRNAs","Hallmarks of cancer","Evading_Apoptosis",22,0.0140811484374027]
["gain ceRNAs","Hallmarks of cancer","Genome_Instability_and_Mutation",14,0.0277914973872369]
["gain ceRNAs","Hallmarks of cancer","Insensitivity_to_Antigrowth_Signals",74,6.99395275027825e-09]
["gain ceRNAs","Hallmarks of cancer","Reprogramming_Energy_Metabolism",11,0.000593212912575636]
["gain ceRNAs","Hallmarks of cancer","Self_Sufficiency_in_Growth_Signals",53,0.00360468155038451]
["gain ceRNAs","Hallmarks of cancer","Sustained_Angiogenesis",17,4.17901871985205e-06]
["gain ceRNAs","Hallmarks of cancer","Tissue_Invasion_and_Metastasis",42,1.00822636461828e-07]
["loss ceRNAs","Hallmarks of cancer","Insensitivity_to_Antigrowth_Signals",52,0.00342628786099497]
["loss ceRNAs","Hallmarks of cancer","Reprogramming_Energy_Metabolism",8,0.0162025897225866]
["loss ceRNAs","Hallmarks of cancer","Self_Sufficiency_in_Growth_Signals",50,0.00607303163455752]
["loss ceRNAs","Hallmarks of cancer","Sustained_Angiogenesis",14,0.000151777433077482]
["loss ceRNAs","Hallmarks of cancer","Tissue_Invasion_and_Metastasis",31,0.000602816397190953]