# Electronic Supplementary Material (ESI) for Organic & Biomolecular Chemistry.
# This journal is © The Royal Society of Chemistry 2015

####################################################################### 
# 
# This file contains crystal structure data downloaded from the 
# Cambridge Structural Database (CSD) hosted by the Cambridge 
# Crystallographic Data Centre (CCDC).
# 
# Full information about CCDC data access policies and citation 
# guidelines are available at http://www.ccdc.cam.ac.uk/access/V1 
# 
# Audit and citation data items may have been added by the CCDC. 
# Please retain this information to preserve the provenance of 
# this file and to allow appropriate attribution of the data. 
# 
#######################################################################

data_glr56
_database_code_depnum_ccdc_archive 'CCDC 645307'
_audit_update_record             
;
2007-04-26 deposited with the CCDC.
2015-03-12 downloaded from the CCDC.
;

_audit_creation_method           SHELXL-97
_chemical_name_systematic        
;
?
;
_chemical_name_common            ?
_chemical_melting_point          ?
_chemical_formula_moiety         ?
_chemical_formula_sum            'C24 H38 O6 Si'
_chemical_formula_weight         450.63

loop_
_atom_type_symbol
_atom_type_description
_atom_type_scat_dispersion_real
_atom_type_scat_dispersion_imag
_atom_type_scat_source
C C 0.0033 0.0016 'International Tables Vol C Tables 4.2.6.8 and 6.1.1.4'
H H 0.0000 0.0000 'International Tables Vol C Tables 4.2.6.8 and 6.1.1.4'
O O 0.0106 0.0060 'International Tables Vol C Tables 4.2.6.8 and 6.1.1.4'
Si Si 0.0817 0.0704 'International Tables Vol C Tables 4.2.6.8 and 6.1.1.4'

_symmetry_cell_setting           Monoclinic
_symmetry_space_group_name_H-M   P2(1)

loop_
_symmetry_equiv_pos_as_xyz
'x, y, z'
'-x, y+1/2, -z'

_cell_length_a                   10.9877(18)
_cell_length_b                   10.2398(16)
_cell_length_c                   12.339(2)
_cell_angle_alpha                90.00
_cell_angle_beta                 110.739(3)
_cell_angle_gamma                90.00
_cell_volume                     1298.4(4)
_cell_formula_units_Z            2
_cell_measurement_temperature    293(2)
_cell_measurement_reflns_used    735
_cell_measurement_theta_min      2.66
_cell_measurement_theta_max      19.20

_exptl_crystal_description       Block
_exptl_crystal_colour            Colourless
_exptl_crystal_size_max          0.40
_exptl_crystal_size_mid          0.30
_exptl_crystal_size_min          0.20
_exptl_crystal_density_meas      0
_exptl_crystal_density_diffrn    1.153
_exptl_crystal_density_method    'not measured'
_exptl_crystal_F_000             488
_exptl_absorpt_coefficient_mu    0.124
_exptl_absorpt_correction_type   SADABS
_exptl_absorpt_correction_T_min  0.659420
_exptl_absorpt_correction_T_max  1.0000
_exptl_absorpt_process_details   ?

_exptl_special_details           
;
?
;

_diffrn_ambient_temperature      293(2)
_diffrn_radiation_wavelength     0.71073
_diffrn_radiation_type           MoK\a
_diffrn_radiation_source         'fine-focus sealed tube'
_diffrn_radiation_monochromator  graphite
_diffrn_measurement_device_type  'BRUKER SMART CCD DIFFRACTOMETER'
_diffrn_measurement_method       'OMEGA SCAN'
_diffrn_detector_area_resol_mean ?
_diffrn_standards_number         ?
_diffrn_standards_interval_count ?
_diffrn_standards_interval_time  ?
_diffrn_standards_decay_%        ?
_diffrn_reflns_number            7061
_diffrn_reflns_av_R_equivalents  0.0450
_diffrn_reflns_av_sigmaI/netI    0.0657
_diffrn_reflns_limit_h_min       -12
_diffrn_reflns_limit_h_max       13
_diffrn_reflns_limit_k_min       -12
_diffrn_reflns_limit_k_max       8
_diffrn_reflns_limit_l_min       -14
_diffrn_reflns_limit_l_max       14
_diffrn_reflns_theta_min         1.76
_diffrn_reflns_theta_max         24.99
_reflns_number_total             3710
_reflns_number_gt                2385
_reflns_threshold_expression     >2sigma(I)

_computing_data_collection       'BRUKER SMART CCD DIFFRACTOMETER'
_computing_cell_refinement       'BRUKER SMART CCD DIFFRACTOMETER'
_computing_data_reduction        'BRUKER SMART CCD DIFFRACTOMETER'
_computing_structure_solution    'SHELXS-97 (Sheldrick, 1990)'
_computing_structure_refinement  'SHELXL-97 (Sheldrick, 1997)'
_computing_molecular_graphics    'SIEMENS SHELXTL'
_computing_publication_material  'SIEMENS SHELXTL'

_refine_special_details          
;
Refinement of F² against ALL reflections. The weighted R-factor wR and
goodness of fit S are based on F², conventional R-factors R are based
on F, with F set to zero for negative F². The threshold expression of
F² > 2sigma(F²) is used only for calculating R-factors(gt) etc. and is
not relevant to the choice of reflections for refinement. R-factors based
on F² are statistically about twice as large as those based on F, and R-
factors based on ALL data will be even larger.
;

_refine_ls_structure_factor_coef Fsqd
_refine_ls_matrix_type           full
_refine_ls_weighting_scheme      calc
_refine_ls_weighting_details     
'calc w=1/[σ²(Fo²)+(0.0875P)²+0.8676P] where P=(Fo²+2Fc²)/3'
_atom_sites_solution_primary     direct
_atom_sites_solution_secondary   difmap
_atom_sites_solution_hydrogens   geom
_refine_ls_hydrogen_treatment    riding
_refine_ls_extinction_method     none
_refine_ls_extinction_coef       ?
_refine_ls_abs_structure_details 'Flack H D (1983), Acta Cryst. A39, 876-881'
_refine_ls_abs_structure_Flack   0.0(3)
_refine_ls_number_reflns         3710
_refine_ls_number_parameters     280
_refine_ls_number_restraints     1
_refine_ls_R_factor_all          0.1071
_refine_ls_R_factor_gt           0.0622
_refine_ls_wR_factor_ref         0.1848
_refine_ls_wR_factor_gt          0.1516
_refine_ls_goodness_of_fit_ref   1.008
_refine_ls_restrained_S_all      1.008
_refine_ls_shift/su_max          0.001
_refine_ls_shift/su_mean         0.000

loop_
_atom_site_label
_atom_site_type_symbol
_atom_site_fract_x
_atom_site_fract_y
_atom_site_fract_z
_atom_site_U_iso_or_equiv
_atom_site_adp_type
_atom_site_occupancy
_atom_site_symmetry_multiplicity
_atom_site_calc_flag
_atom_site_refinement_flags
_atom_site_disorder_assembly
_atom_site_disorder_group
Si1 Si 0.79268(15) 0.41827(18) 0.79473(14) 0.0584(5) Uani 1 1 d . . .
O1 O 0.6673(3) 0.3577(4) 0.6893(3) 0.0497(10) Uani 1 1 d . . .
O2 O 0.4568(3) 0.2343(4) 0.5164(3) 0.0502(10) Uani 1 1 d . . .
H2A H 0.5137 0.1851 0.5569 0.075 Uiso 1 1 calc R . .
O3 O 0.4380(4) 0.3757(5) 0.7790(3) 0.0704(13) Uani 1 1 d . . .
O4 O 0.2207(4) 0.3576(5) 0.7158(3) 0.0694(13) Uani 1 1 d . . .
O5 O 0.0847(3) 0.3617(4) 0.4771(3) 0.0561(10) Uani 1 1 d . . .
O6 O 0.3557(4) 0.5428(5) 0.3779(4) 0.0675(12) Uani 1 1 d . . .
C1 C 0.5575(5) 0.4290(6) 0.6202(5) 0.0479(14) Uani 1 1 d . . .
H1A H 0.5714 0.4619 0.5518 0.058 Uiso 1 1 calc R . .
H1B H 0.5431 0.5027 0.6635 0.058 Uiso 1 1 calc R . .
C2 C 0.9022(7) 0.5083(7) 0.7348(7) 0.077(2) Uani 1 1 d . . .
H2B H 0.8573 0.5831 0.6923 0.116 Uiso 1 1 calc R . .
H2C H 0.9271 0.4519 0.6841 0.116 Uiso 1 1 calc R . .
H2D H 0.9785 0.5364 0.7972 0.116 Uiso 1 1 calc R . .
C3 C 0.7332(7) 0.5290(8) 0.8844(6) 0.0710(19) Uani 1 1 d . . .
H3A H 0.6773 0.4814 0.9150 0.106 Uiso 1 1 calc R . .
H3B H 0.6855 0.5999 0.8374 0.106 Uiso 1 1 calc R . .
H3C H 0.8060 0.5631 0.9471 0.106 Uiso 1 1 calc R . .
C4 C 0.8802(6) 0.2742(7) 0.8785(5) 0.0649(18) Uani 1 1 d . . .
C5 C 0.9928(8) 0.3275(9) 0.9882(6) 0.102(3) Uani 1 1 d . . .
H5A H 1.0410 0.2555 1.0329 0.152 Uiso 1 1 calc R . .
H5B H 0.9562 0.3780 1.0347 0.152 Uiso 1 1 calc R . .
H5C H 1.0499 0.3816 0.9640 0.152 Uiso 1 1 calc R . .
C6 C 0.9415(6) 0.1938(8) 0.8065(6) 0.072(2) Uani 1 1 d . . .
H6A H 0.9864 0.1202 0.8511 0.108 Uiso 1 1 calc R . .
H6B H 1.0020 0.2471 0.7861 0.108 Uiso 1 1 calc R . .
H6C H 0.8745 0.1636 0.7373 0.108 Uiso 1 1 calc R . .
C7 C 0.7784(9) 0.1912(9) 0.9138(7) 0.103(3) Uani 1 1 d . . .
H7A H 0.8207 0.1155 0.9566 0.155 Uiso 1 1 calc R . .
H7B H 0.7085 0.1643 0.8452 0.155 Uiso 1 1 calc R . .
H7C H 0.7444 0.2435 0.9611 0.155 Uiso 1 1 calc R . .
C8 C 0.4399(5) 0.3387(6) 0.5850(4) 0.0423(13) Uani 1 1 d . . .
C9 C 0.4105(5) 0.2827(6) 0.6890(4) 0.0495(15) Uani 1 1 d . . .
H9A H 0.4560 0.2001 0.7161 0.059 Uiso 1 1 calc R . .
C10 C 0.2606(5) 0.2664(7) 0.6484(5) 0.0530(15) Uani 1 1 d . . .
H10A H 0.2358 0.1769 0.6597 0.064 Uiso 1 1 calc R . .
C11 C 0.2101(5) 0.3052(6) 0.5201(5) 0.0452(14) Uani 1 1 d . . .
H11A H 0.2120 0.2286 0.4731 0.054 Uiso 1 1 calc R . .
C12 C 0.3104(4) 0.4049(6) 0.5120(4) 0.0419(12) Uani 1 1 d . . .
H12A H 0.3008 0.4843 0.5526 0.050 Uiso 1 1 calc R . .
C13 C 0.3315(6) 0.3862(8) 0.8177(5) 0.072(2) Uani 1 1 d . . .
C14 C 0.3227(10) 0.5261(10) 0.8514(8) 0.114(3) Uani 1 1 d . . .
H14A H 0.3153 0.5820 0.7869 0.171 Uiso 1 1 calc R . .
H14B H 0.3996 0.5486 0.9157 0.171 Uiso 1 1 calc R . .
H14C H 0.2476 0.5370 0.8732 0.171 Uiso 1 1 calc R . .
C15 C 0.3448(8) 0.2861(10) 0.9122(6) 0.104(3) Uani 1 1 d . . .
H15A H 0.3494 0.2001 0.8829 0.156 Uiso 1 1 calc R . .
H15B H 0.2708 0.2917 0.9361 0.156 Uiso 1 1 calc R . .
H15C H 0.4227 0.3033 0.9773 0.156 Uiso 1 1 calc R . .
C16 C -0.0161(5) 0.2713(7) 0.4734(5) 0.0639(18) Uani 1 1 d . . .
H16A H -0.0203 0.2616 0.5502 0.077 Uiso 1 1 calc R . .
H16B H 0.0027 0.1865 0.4480 0.077 Uiso 1 1 calc R . .
C17 C -0.1432(5) 0.3203(7) 0.3916(5) 0.0554(17) Uani 1 1 d . . .
C18 C -0.2540(6) 0.3074(9) 0.4171(6) 0.079(2) Uani 1 1 d . . .
H18A H -0.2481 0.2725 0.4884 0.095 Uiso 1 1 calc R . .
C19 C -0.3744(6) 0.3448(12) 0.3400(7) 0.103(3) Uani 1 1 d . . .
H19A H -0.4486 0.3337 0.3587 0.124 Uiso 1 1 calc R . .
C20 C -0.3833(6) 0.3986(9) 0.2353(7) 0.088(3) Uani 1 1 d . . .
H20A H -0.4633 0.4257 0.1829 0.105 Uiso 1 1 calc R . .
C21 C -0.2747(7) 0.4116(10) 0.2096(6) 0.090(2) Uani 1 1 d . . .
H21A H -0.2807 0.4464 0.1383 0.108 Uiso 1 1 calc R . .
C22 C -0.1560(6) 0.3751(9) 0.2859(6) 0.077(2) Uani 1 1 d . . .
H22A H -0.0824 0.3872 0.2664 0.093 Uiso 1 1 calc R . .
C23 C 0.3056(5) 0.4430(6) 0.3929(5) 0.0474(14) Uani 1 1 d . . .
C24 C 0.2456(6) 0.3532(7) 0.2942(5) 0.0644(17) Uani 1 1 d . . .
H24A H 0.2522 0.3903 0.2250 0.097 Uiso 1 1 calc R . .
H24B H 0.1556 0.3402 0.2837 0.097 Uiso 1 1 calc R . .
H24C H 0.2901 0.2708 0.3098 0.097 Uiso 1 1 calc R . .


_geom_special_details            
;
All esds (except the esd in the dihedral angle between two l.s. planes)
are estimated using the full covariance matrix. The cell esds are taken
into account individually in the estimation of esds in distances, angles
and torsion angles; correlations between esds in cell parameters are only
used when they are defined by crystal symmetry. An approximate (isotropic)
treatment of cell esds is used for estimating esds involving l.s. planes.
;

loop_
_geom_bond_atom_site_label_1
_geom_bond_atom_site_label_2
_geom_bond_distance
_geom_bond_site_symmetry_2
_geom_bond_publ_flag
Si1 O1 1.645(4) . ?
Si1 C3 1.858(7) . ?
Si1 C4 1.861(7) . ?
Si1 C2 1.864(7) . ?
O1 C1 1.409(6) . ?
O2 C8 1.415(6) . ?
O3 C9 1.412(7) . ?
O3 C13 1.416(7) . ?
O4 C10 1.420(7) . ?
O4 C13 1.437(7) . ?
O5 C11 1.413(6) . ?
O5 C16 1.431(7) . ?
O6 C23 1.206(7) . ?
C1 C8 1.522(8) . ?
C4 C6 1.531(9) . ?
C4 C5 1.574(9) . ?
C4 C7 1.584(10) . ?
C8 C9 1.541(7) . ?
C8 C12 1.545(7) . ?
C9 C10 1.551(8) . ?
C10 C11 1.533(7) . ?
C11 C12 1.531(8) . ?
C12 C23 1.503(7) . ?
C13 C14 1.505(13) . ?
C13 C15 1.520(11) . ?
C16 C17 1.491(8) . ?
C17 C18 1.367(8) . ?
C17 C22 1.381(8) . ?
C18 C19 1.382(10) . ?
C19 C20 1.377(11) . ?
C20 C21 1.345(9) . ?
C21 C22 1.363(9) . ?
C23 C24 1.482(8) . ?

loop_
_geom_angle_atom_site_label_1
_geom_angle_atom_site_label_2
_geom_angle_atom_site_label_3
_geom_angle
_geom_angle_site_symmetry_1
_geom_angle_site_symmetry_3
_geom_angle_publ_flag
O1 Si1 C3 109.2(3) . . ?
O1 Si1 C4 105.3(3) . . ?
C3 Si1 C4 112.0(3) . . ?
O1 Si1 C2 110.5(3) . . ?
C3 Si1 C2 110.3(4) . . ?
C4 Si1 C2 109.5(3) . . ?
C1 O1 Si1 125.5(4) . . ?
C9 O3 C13 110.1(4) . . ?
C10 O4 C13 107.7(4) . . ?
C11 O5 C16 112.8(4) . . ?
O1 C1 C8 108.5(5) . . ?
C6 C4 C5 108.2(5) . . ?
C6 C4 C7 111.7(7) . . ?
C5 C4 C7 111.4(6) . . ?
C6 C4 Si1 110.6(4) . . ?
C5 C4 Si1 107.3(5) . . ?
C7 C4 Si1 107.6(5) . . ?
O2 C8 C1 110.5(4) . . ?
O2 C8 C9 109.1(5) . . ?
C1 C8 C9 113.3(4) . . ?
O2 C8 C12 105.8(4) . . ?
C1 C8 C12 114.4(5) . . ?
C9 C8 C12 103.1(4) . . ?
O3 C9 C8 110.7(5) . . ?
O3 C9 C10 103.6(5) . . ?
C8 C9 C10 106.4(4) . . ?
O4 C10 C11 111.2(5) . . ?
O4 C10 C9 104.6(5) . . ?
C11 C10 C9 105.1(4) . . ?
O5 C11 C12 109.3(4) . . ?
O5 C11 C10 116.2(4) . . ?
C12 C11 C10 103.5(4) . . ?
C23 C12 C11 117.3(4) . . ?
C23 C12 C8 112.9(4) . . ?
C11 C12 C8 101.8(4) . . ?
O3 C13 O4 103.6(4) . . ?
O3 C13 C14 107.8(6) . . ?
O4 C13 C14 108.6(6) . . ?
O3 C13 C15 109.9(6) . . ?
O4 C13 C15 110.8(6) . . ?
C14 C13 C15 115.3(7) . . ?
O5 C16 C17 109.5(5) . . ?
C18 C17 C22 117.2(6) . . ?
C18 C17 C16 120.6(6) . . ?
C22 C17 C16 122.2(5) . . ?
C17 C18 C19 121.8(7) . . ?
C20 C19 C18 119.3(6) . . ?
C21 C20 C19 119.1(7) . . ?
C20 C21 C22 121.5(7) . . ?
C21 C22 C17 121.1(6) . . ?
O6 C23 C24 119.6(5) . . ?
O6 C23 C12 120.7(5) . . ?
C24 C23 C12 119.6(5) . . ?

_diffrn_measured_fraction_theta_max 1.000
_diffrn_reflns_theta_full        24.99
_diffrn_measured_fraction_theta_full 1.000
_refine_diff_density_max         1.092
_refine_diff_density_min         -0.332
_refine_diff_density_rms         0.050


