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["Table S4  Differentially expressed miRNAs  in each differential analysis groups"]
["sRNA","E90","E60","log2.Fold_change.","p.value","q.value",null,"sRNA","D30","E90","log2.Fold_change.","p.value","q.value",null,"sRNA","DM","D30","log2.Fold_change.","p.value","q.value"]
["ssc-let-7c",11972.1478314822,3448.3544544938,1.7957,0,0,null,"novel_45",1690.38251479431,86.2430030763462,4.2928,0,0,null,"ssc-let-7c",2582.259724182,5739.76514281388,-1.1524,0,0]
["ssc-let-7i",65655.9617623918,23720.5755736773,1.4688,0,0,null,"novel_46",1539.90805929819,56.0411732052522,4.7802,0,0,null,"ssc-miR-1",8653.52686195343,1491.41869270512,2.5366,0,0]
["ssc-miR-1",46877.2504762433,827.579741465918,5.8238,0,0,null,"ssc-let-7c",5255.83513923394,12914.6380287672,-1.297,0,0,null,"ssc-miR-100",31702.3772899029,8737.47865993053,1.8593,0,0]
["ssc-miR-100",29796.135934707,12331.69797622,1.2728,0,0,null,"ssc-let-7i",34463.4021335218,70824.6333512652,-1.0392,0,0,null,"ssc-miR-125a",920.827622472753,3822.81989199526,-2.0536,0,0]
["ssc-miR-101",3544.51480815664,9488.04027237648,-1.4205,0,0,null,"ssc-miR-1",1365.67447925005,50567.5949049476,-5.2105,0,0,null,"ssc-miR-125b",1374.20146717646,4467.33694708912,-1.7008,0,0]
["ssc-miR-10a-5p",45297.5553563715,17058.147081172,1.409,0,0,null,"ssc-miR-100",8000.80599581053,32141.7940764806,-2.0062,0,0,null,"ssc-miR-143-3p",125756.330166325,30452.8254292202,2.046,0,0]
["ssc-miR-125b",9872.31678399606,4255.67210588557,1.214,0,0,null,"ssc-miR-101",10835.7447373574,3823.5516616805,1.5028,0,0,null,"ssc-miR-152",1529.08073089512,3920.03368291388,-1.3582,0,0]
["ssc-miR-127",4040.38602144449,788.005346789851,2.3582,0,0,null,"ssc-miR-10a-5p",2130.08471317034,48863.540548443,-4.5198,0,0,null,"ssc-miR-181a",1948.66273624203,4888.36607003557,-1.3269,0,0]
["ssc-miR-140-3p",5247.40001614764,19356.9445191154,-1.8832,0,0,null,"ssc-miR-127",393.134314254073,4358.45962628632,-3.4707,0,0,null,"ssc-miR-199a-3p",2354.16480852361,14402.1712311098,-2.613,0,0]
["ssc-miR-155-5p",1640.66799176919,57.6203186483539,4.8316,0,0,null,"ssc-miR-191",4779.38549488412,2377.89073851747,1.0071,0,0,null,"ssc-miR-199a-5p",3117.29718066464,10379.3884524563,-1.7354,0,0]
["ssc-miR-199a-3p",29341.6391702067,12431.1088556462,1.239,0,0,null,"ssc-miR-199a-3p",13187.8980680073,31651.5177049065,-1.2631,0,0,null,"ssc-miR-199b-3p",2354.16480852361,14401.8252745584,-2.613,0,0]
["ssc-miR-199a-5p",21573.8197249134,10479.9329005374,1.0417,0,0,null,"ssc-miR-199a-5p",9504.28339746228,23272.1877951152,-1.292,0,0,null,"ssc-miR-199b-5p",1081.33885941754,9571.57990514325,-3.1459,0,0]
["ssc-miR-199b-3p",29339.1504815578,12430.159070174,1.239,0,0,null,"ssc-miR-199b-3p",13187.5812796799,31648.8330978068,-1.263,0,0,null,"ssc-miR-34c",26670.209212353,25.2548282457606,10.044,0,0]
["ssc-miR-199b-5p",18772.1784784452,9178.72680358834,1.0322,0,0,null,"ssc-miR-199b-5p",8764.5826530761,20249.9913526811,-1.2082,0,0,null,"ssc-miR-450a",1458.68106556846,5860.84993577301,-2.0064,0,0]
["ssc-miR-202-5p",2512.953363199,16246.7136927339,-2.6927,0,0,null,"ssc-miR-202-5p",30949.2692181146,2710.78201887441,3.5131,0,0,null,"ssc-miR-450b-5p",1971.19062914657,6620.91647900501,-1.748,0,0]
["ssc-miR-206",3406.08150206311,208.00301841741,4.0334,0,0,null,"ssc-miR-206",44.3503658304353,3674.22039176231,-6.3723,0,0,null,"ssc-miR-450c-5p",2559.73183127747,6957.53220343138,-1.4426,0,0]
["ssc-miR-20a",1373.1339620154,3887.47193781944,-1.5014,0,0,null,"ssc-miR-214",960.818996883645,4637.65876465021,-2.2711,0,0,null,"ssc-miR-542-3p",1368.56949395033,7754.96205420505,-2.5025,0,0]
["ssc-miR-450a",1638.49038920143,6441.44507263412,-1.975,0,0,null,"ssc-miR-450a",5366.71105381003,1767.47819923391,1.6023,0,0,null,"ssc-miR-9",1779.70353945804,94.7920950594301,4.2307,0,0]
["ssc-miR-450b-5p",1962.64208571707,6222.67781886482,-1.6647,0,0,null,"ssc-miR-450b-5p",6062.6950090205,2117.14827396369,1.5178,0,0,null,"ssc-miR-9-1",1779.70353945804,94.7920950594301,4.2307,0,0]
["ssc-miR-450c-5p",2861.99194620336,11032.7080453727,-1.9467,0,0,null,"ssc-miR-450c-5p",6370.93005154203,3087.29816460072,1.0452,0,0,null,"ssc-miR-92a",2855.41042564945,9143.63165117057,-1.6791,0,0]
["ssc-miR-451",6944.68567467868,1382.88764756049,2.3282,0,0,null,"ssc-miR-542-3p",7101.12714610741,2790.98465597654,1.3473,0,0,null,"novel_46",4691.43369736883,1681.6947959266,1.4801,4.5296e-245,6.5737e-245]
["ssc-miR-542-3p",2587.30293658406,18783.5906890486,-2.86,0,0,null,"ssc-miR-125b",4090.68767120294,10649.5007884352,-1.3804,9.42169999999999e-306,2.8825e-305,null,"ssc-let-7e",1616.37631590018,3638.07909359477,-1.1704,9.1487e-240,1.2875e-239]
["ssc-miR-145-5p",4875.65214922232,1827.70384371949,1.4156,6.9112e-222,5.5574e-221,null,"ssc-miR-155-5p",221.751829152176,1769.82723044611,-2.9966,6.7924e-217,1.9482e-216,null,"ssc-miR-221-3p",242.174848723721,1307.36980740725,-2.4325,9.5205e-206,1.2282e-205]
["ssc-miR-133a-3p",989.875910089033,6.33190314817076,7.2885,1.2087e-208,9.092e-208,null,"ssc-miR-133a-3p",36.1138693190687,1067.8024738869,-4.8859,2.4272e-206,6.7509e-206,null,"ssc-miR-182",2207.73350464415,531.043306263595,2.0557,3.1152e-198,3.9101e-198]
["ssc-miR-214",4299.20964092723,1568.4124098019,1.4548,4.4261e-206,3.2254e-205,null,"novel_53",769.162058830692,48.9940795686636,3.9726,7.0837e-203,1.9123e-202,null,"ssc-miR-148b-3p",1447.41711911619,3053.75847842916,-1.0771,6.4486e-181,7.679e-181]
["novel_45",79.9491228450287,841.826523549303,-3.3964,4.7469e-181,3.3544e-180,null,"ssc-miR-218-5p",883.839433335103,3216.83045715897,-1.8638,2.0324e-180,5.0417e-180,null,"ssc-miR-20a",1193.97832394021,2706.41810091212,-1.1806,8.3793e-181,9.7286e-181]
["novel_53",45.4185678419229,684.478730317259,-3.9137,7.4366e-161,5.1005e-160,null,"ssc-miR-361-3p",976.975201579017,237.252152431816,2.0419,3.0196e-160,7.1066e-160,null,"ssc-miR-183",903.931702794354,49.4717868375858,4.1915,8.4273e-179,9.5456e-179]
["novel_46",51.9513755452132,641.738384067107,-3.6268,1.5808e-144,1.024e-143,null,"ssc-miR-27a",1061.87447331156,372.153659189369,1.5126,3.2769e-130,7.3359e-130,null,"ssc-miR-181b",154.879263718659,957.607734031031,-2.6283,5.6314e-163,6.2269e-163]
["ssc-miR-708-3p",209.983104748616,843.726094493754,-2.0065,1.3814e-112,8.2601e-112,null,"ssc-miR-221-3p",1197.14308909439,522.491656769926,1.1961,1.6995e-115,3.7141e-115,null,"ssc-miR-127",42.2397991959978,429.33208017793,-3.3454,1.8248e-90,1.8031e-90]
["ssc-miR-182",107.013611901517,609.762273168844,-2.5105,1.0274e-102,5.9896e-102,null,"ssc-miR-29a",477.08322100454,50.33638311849,3.2446,6.4527e-114,1.3773e-113,null,"ssc-miR-214",422.397991959978,1049.28622012865,-1.3127,1.9827e-81,1.8416e-81]
["ssc-miR-196b-5p",438.942460444885,20.8952803889635,4.3928,6.5726e-89,3.4834e-88,null,"ssc-miR-222",730.830671220102,226.513724033205,1.6899,1.2856e-100,2.6818e-100,null,"ssc-miR-17-5p",261.886755015187,801.581329389414,-1.6139,1.2111e-80,1.1029e-80]
["ssc-miR-378",1175.28321443003,325.143226658569,1.8539,2.7345e-87,1.4171e-86,null,"ssc-miR-186",1056.48907174644,492.289826898832,1.1017,6.0106e-94,1.226e-93,null,"ssc-miR-186",518.14153680424,1153.76509862481,-1.1549,5.7905e-76,5.1715e-76]
["ssc-miR-17-5p",363.037456654274,893.431534206894,-1.2992,5.4987e-72,2.6714e-71,null,"ssc-miR-378",288.59416622519,1267.80570281103,-2.1352,7.6264e-93,1.5217e-92,null,"ssc-miR-361-3p",461.82180454291,1066.93000424556,-1.2081,1.5886e-74,1.392e-74]
["ssc-miR-424-5p",117.279452578116,467.611047492411,-1.9954,7.4335e-63,3.5377e-62,null,"ssc-miR-451",3727.64824804809,7491.39611158113,-1.007,5.3853e-89,1.0088e-88,null,"ssc-miR-320",306.942540824251,828.565940391734,-1.4326,4.3879e-72,3.7737e-72]
["ssc-miR-19b",368.637006114237,791.804488678754,-1.1029,2.0752e-52,9.3064e-52,null,"ssc-miR-196b-5p",20.9080296057766,473.497577201262,-4.5012,2.442e-88,4.3948e-88,null,"ssc-miR-424-5p",137.98334404026,548.687090380497,-1.9915,5.8727e-71,4.9588e-71]
["ssc-miR-196a",338.772742327768,46.8560832964636,2.854,2.505e-47,1.1022e-46,null,"ssc-miR-182",486.270082497987,115.43810528507,2.0746,6.7974e-82,1.1772e-81,null,"novel_53",1878.26307091537,839.982506585023,1.161,3.0749e-63,2.5501e-63]
["ssc-miR-676-3p",188.518165152091,491.039089140643,-1.3811,2.0997e-43,8.7437e-43,null,"ssc-miR-424-5p",502.42628719336,126.512109571138,1.9896,2.1715e-81,3.6909e-81,null,"ssc-miR-107",323.83846050265,790.164763196125,-1.2869,2.9637e-60,2.373e-60]
["ssc-miR-140-5p",229.892613939596,539.16155306674,-1.2298,2.4966e-41,1.0214e-40,null,"ssc-miR-202-3p",382.046722796464,68.1219051536898,2.4876,1.2423e-75,2.0361e-75,null,"ssc-miR-96-5p",301.310567598118,24.9088716944488,3.5965,2.168e-54,1.6506e-54]
["ssc-miR-369",327.88472948895,53.8211767594515,2.6069,3.534e-41,1.4209e-40,null,"ssc-miR-146a-5p",278.456939749662,23.490312121962,3.5673,5.1076e-71,8.0827e-71,null,"ssc-miR-676-3p",28.1598661306652,259.12145693253,-3.2019,1.351e-53,1.012e-53]
["ssc-miR-202-3p",63.1504744651394,275.437786945428,-2.1249,2.7377e-40,1.0821e-39,null,"ssc-miR-196a",17.4233580048139,365.442141440237,-4.3905,1.77e-67,2.7535e-67,null,"ssc-miR-29a",1264.37798926687,521.010566275554,1.279,8.5647e-52,6.2149e-52]
["ssc-miR-708-5p",115.412936091462,355.21976661238,-1.6219,2.3311e-38,9.0602e-38,null,"ssc-miR-369",20.5912412784164,353.696985379256,-4.1024,3.7815e-62,5.6899e-62,null,"ssc-miR-126-5p",847.611970533023,281.262676216484,1.5915,1.0116e-51,7.2276e-52]
["ssc-miR-452",76.21608987172,281.136499778782,-1.8831,3.3901e-36,1.296e-35,null,"ssc-miR-708-3p",538.540156512429,226.513724033205,1.2495,2.4771e-55,3.667e-55,null,"ssc-miR-339-5p",137.98334404026,452.511169115819,-1.7135,1.1625e-49,8.0577e-50]
["ssc-miR-149",113.546419604807,331.791724964148,-1.547,4.6401e-34,1.7175e-33,null,"ssc-miR-142-5p",303.166429283761,79.5314853272142,1.9305,1.7652e-48,2.4926e-48,null,"ssc-miR-222",382.974179377047,798.121763876296,-1.0594,1.362e-47,9.1669e-48]
["ssc-miR-183",24.2647143265068,172.227765630245,-2.8274,1.4235e-33,5.1868e-33,null,"ssc-miR-425-5p",485.319717515906,224.500268708465,1.1122,1.5061e-44,2.0945e-44,null,"ssc-miR-139-5p",926.459595698886,342.496985798671,1.4356,3.0183e-47,2.0025e-47]
["ssc-miR-133b",136.566789606878,1.26638062963415,6.7528,3.7033e-31,1.3286e-30,null,"ssc-miR-320",758.708044027804,1754.72631551056,-1.2096,4.395e-37,5.8462e-37,null,"ssc-miR-155-5p",36.6078259698648,242.169585918252,-2.7258,5.1993e-44,3.4008e-44]
["ssc-miR-23a",936.369104138274,431.202604390429,1.1187,4.843e-28,1.6608e-27,null,"ssc-miR-708-5p",315.204385723451,124.498654246399,1.3402,1.8193e-35,2.3519e-35,null,"ssc-miR-149",30.9758527437318,219.682410082986,-2.8262,2.31e-41,1.49e-41]
["ssc-miR-32",71.238712573975,222.566395658202,-1.6435,5.0809e-25,1.6926e-24,null,"ssc-miR-133b",1.58394163680126,147.317814593447,-6.5393,8.4431e-32,1.0616e-31,null,"ssc-miR-221-5p",107.007491296528,334.885941669811,-1.646,1.6022e-35,9.9213e-36]
["ssc-let-7d-5p",880.373609538643,438.167697853417,1.0066,2.4868e-21,8.1677e-21,null,"ssc-miR-335",32.629197718106,240.272335418925,-2.8804,1.7309e-29,2.0633e-29,null,"ssc-miR-455-3p",36.6078259698648,205.498191479202,-2.4889,1.2831e-34,7.8404e-35]
["ssc-miR-34c",10.265840676599,94.9785472225614,-3.2097,3.6832e-21,1.1929e-20,null,"ssc-miR-32",221.435040824816,76.8468782275614,1.5268,8.2919e-29,9.6337e-29,null,"ssc-miR-374b-5p",98.5595314573283,312.744722385857,-1.6659,9.4531e-34,5.7014e-34]
["ssc-miR-136",161.142590014494,29.7599447964026,2.4369,2.0868e-19,6.5761e-19,null,"ssc-miR-136",14.5722630585716,173.828309702519,-3.5764,7.7892e-28,8.9366e-28,null,"ssc-miR-1839-5p",278.782674693586,55.3530482098862,2.3324,1.5555e-31,9.2616e-32]
["ssc-miR-135",35.463813246433,136.135917685671,-1.9406,6.0947e-19,1.895e-18,null,"ssc-miR-221-5p",306.651100884724,148.660118143274,1.0446,4.5875e-27,5.1349e-27,null,"ssc-miR-363",42.2397991959978,203.768408722643,-2.2703,2.0754e-31,1.2201e-31]
["ssc-miR-145-3p",408.767110577306,164.312886695031,1.3148,1.1266e-17,3.4119e-17,null,"ssc-miR-493-5p",13.3051097491306,150.673573468013,-3.5014,7.7351e-24,8.3525e-24,null,"ssc-miR-142-5p",118.271437748794,331.080419605382,-1.4851,3.7806e-31,2.1676e-31]
["ssc-miR-204",349.971841247694,133.919751583812,1.3859,7.6335e-17,2.2822e-16,null,"ssc-miR-195",203.061317837922,79.1959094397576,1.3584,9.6199e-24,1.0267e-23,null,"ssc-miR-769-5p",647.6769210053,254.278065214165,1.3489,4.4194e-30,2.4728e-30]
["ssc-miR-133a-5p",64.0837327084666,1.26638062963415,5.6612,1.2445e-15,3.5829e-15,null,"ssc-miR-574",148.256937204598,472.490849538893,-1.6722,1.1016e-22,1.1361e-22,null,"ssc-miR-181d-5p",59.135718874397,210.687539748879,-1.833,6.902e-26,3.771e-26]
["ssc-miR-215",74.6606594661747,5.38211767594515,3.7941,4.8844e-15,1.3723e-14,null,"ssc-miR-1285",123.230659343138,27.8527986588978,2.1455,1.1448e-22,1.1675e-22,null,"ssc-miR-204",363.262273085581,119.355010202567,1.6058,1.8507e-23,9.8792e-24]
["ssc-miR-96-5p",6.53280770329028,63.3190314817076,-3.2769,7.9628e-15,2.2106e-14,null,"ssc-miR-10a-3p",5.70218989248454,111.411194635591,-4.2882,2.0778e-21,2.0729e-21,null,"ssc-miR-374a-5p",47.8717724221309,170.556579796712,-1.833,2.9033e-21,1.5322e-21]
["ssc-miR-10a-3p",103.280578928208,16.1463530278354,2.6773,1.6945e-14,4.6489e-14,null,"ssc-miR-204",109.291972939287,377.522873388675,-1.7884,5.2703e-21,5.2014e-21,null,"ssc-miR-129a-5p",160.511236944792,29.406306861502,2.4485,5.175e-20,2.7004e-20]
["ssc-miR-486",99.5475459548996,14.8799723982013,2.742,2.0879e-14,5.5963e-14,null,"ssc-miR-146b",305.700735902643,739.273680066889,-1.274,8.2839e-19,8.0886e-19,null,"ssc-miR-7136-5p",104.191504683461,11.0706096419772,3.2344,3.6869e-18,1.8611e-18]
["ssc-miR-205",58.1730971673944,1.89957094445123,4.9366,6.965e-14,1.8457e-13,null,"ssc-miR-382",10.1372264755281,114.431377622701,-3.4967,1.8392e-18,1.7769e-18,null,"ssc-miR-122",73.2156519397296,3.80552206442967,4.266,3.3827e-16,1.6537e-16]
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