# Electronic Supplementary Material (ESI) for ChemComm.
# This journal is © The Royal Society of Chemistry 2019

####################################################################### 
# 
# This file contains crystal structure data downloaded from the 
# Cambridge Structural Database (CSD) hosted by the Cambridge 
# Crystallographic Data Centre (CCDC).
# 
# Full information about CCDC data access policies and citation 
# guidelines are available at http://www.ccdc.cam.ac.uk/access/V1 
# 
# Audit and citation data items may have been added by the CCDC. 
# Please retain this information to preserve the provenance of 
# this file and to allow appropriate attribution of the data. 
# 
#######################################################################

data_cu_B_0m_a
_database_code_depnum_ccdc_archive 'CCDC 1853052'
loop_
_audit_author_name
_audit_author_address
'Kristin Kirschbaum'
;University of Toledo CNSM Instrumentation Center
United States of America
;
_audit_update_record             
;
2018-07-03 deposited with the CCDC.	2019-05-17 downloaded from the CCDC.
;

_audit_creation_method           SHELXL-2016/6
_shelx_SHELXL_version_number     2016/6
_chemical_name_systematic        
(2R,4aR,9bR)-4a-methyl-2-((E)-styryl)-3,4,4a,9b-tetrahydro-2H-pyrano[3,2-b]benzofuran
_chemical_name_common            ?
_chemical_melting_point          ?
_chemical_formula_moiety         'C20 H20 O2'
_chemical_formula_sum            'C20 H20 O2'
_chemical_formula_weight         292.36

loop_
_atom_type_symbol
_atom_type_description
_atom_type_scat_dispersion_real
_atom_type_scat_dispersion_imag
_atom_type_scat_source
C C 0.0181 0.0091 'International Tables Vol C Tables 4.2.6.8 and 6.1.1.4'
H H 0.0000 0.0000 'International Tables Vol C Tables 4.2.6.8 and 6.1.1.4'
O O 0.0492 0.0322 'International Tables Vol C Tables 4.2.6.8 and 6.1.1.4'

_space_group_crystal_system      monoclinic
_space_group_IT_number           5
_space_group_name_H-M_alt        'C 2'
_space_group_name_Hall           'C 2y'

_shelx_space_group_comment       
;
The symmetry employed for this shelxl refinement is uniquely defined
by the following loop, which should always be used as a source of
symmetry information in preference to the above space-group names.
They are only intended as comments.
;

loop_
_space_group_symop_operation_xyz
'x, y, z'
'-x, y, -z'
'x+1/2, y+1/2, z'
'-x+1/2, y+1/2, -z'

_cell_length_a                   16.7276(7)
_cell_length_b                   5.4692(2)
_cell_length_c                   17.8067(8)
_cell_angle_alpha                90
_cell_angle_beta                 103.573(2)
_cell_angle_gamma                90
_cell_volume                     1583.58(11)
_cell_formula_units_Z            4
_cell_measurement_temperature    200(2)
_cell_measurement_reflns_used    9409
_cell_measurement_theta_min      2.55
_cell_measurement_theta_max      70.90

_exptl_crystal_description       irregular
_exptl_crystal_colour            colorless
_exptl_crystal_density_meas      ?
_exptl_crystal_density_method    ?
_exptl_crystal_density_diffrn    1.226
_exptl_crystal_F_000             624
_exptl_transmission_factor_min   ?
_exptl_transmission_factor_max   ?
_exptl_crystal_size_max          0.239
_exptl_crystal_size_mid          0.109
_exptl_crystal_size_min          0.058
_exptl_absorpt_coefficient_mu    0.611
_shelx_estimated_absorpt_T_min   ?
_shelx_estimated_absorpt_T_max   ?
_exptl_absorpt_correction_type   multi-scan
_exptl_absorpt_correction_T_min  0.604
_exptl_absorpt_correction_T_max  0.753
_exptl_absorpt_process_details   
;
 SADABS 2016/2: Krause, L., Herbst-Irmer, R., Sheldrick G.M. & Stalke D.,
 J. Appl. Cryst. 48 (2015) 3-10
;
_diffrn_ambient_temperature      200(2)
_diffrn_radiation_wavelength     1.54178
_diffrn_radiation_type           CuK\a
_diffrn_source                   ImuS
_diffrn_measurement_device_type  'Bruker APEX-II CCD'
_diffrn_measurement_method       'φ and ω scans'
_diffrn_detector_area_resol_mean ?
_diffrn_reflns_number            29320
_diffrn_reflns_av_unetI/netI     0.0171
_diffrn_reflns_av_R_equivalents  0.0364
_diffrn_reflns_limit_h_min       -20
_diffrn_reflns_limit_h_max       20
_diffrn_reflns_limit_k_min       -6
_diffrn_reflns_limit_k_max       6
_diffrn_reflns_limit_l_min       -21
_diffrn_reflns_limit_l_max       21
_diffrn_reflns_theta_min         2.553
_diffrn_reflns_theta_max         70.939
_diffrn_reflns_theta_full        66.500
_diffrn_measured_fraction_theta_max 0.997
_diffrn_measured_fraction_theta_full 1.000
_diffrn_reflns_Laue_measured_fraction_max 0.997
_diffrn_reflns_Laue_measured_fraction_full 1.000
_diffrn_reflns_point_group_measured_fraction_max 0.993
_diffrn_reflns_point_group_measured_fraction_full 0.998
_reflns_number_total             3045
_reflns_number_gt                2948
_reflns_threshold_expression     'I > 2σ(I)'
_reflns_Friedel_coverage         0.790
_reflns_Friedel_fraction_max     0.987
_reflns_Friedel_fraction_full    0.996

_reflns_special_details          
;
 Reflections were merged by SHELXL according to the crystal
 class for the calculation of statistics and refinement.
 
 _reflns_Friedel_fraction is defined as the number of unique
 Friedel pairs measured divided by the number that would be
 possible theoretically, ignoring centric projections and
 systematic absences.
;

_computing_data_collection       'Bruker APEX3'
_computing_cell_refinement       'Bruker SAINT'
_computing_data_reduction        'Bruker SAINT'
_computing_structure_solution    'SHELXT 2014/5 (Sheldrick, 2014)'
_computing_structure_refinement  'SHELXL-2016/6 (Sheldrick, 2016)'
_computing_molecular_graphics    'Diamond 3.0'
_computing_publication_material  ?
_refine_special_details          ?
_refine_ls_structure_factor_coef Fsqd
_refine_ls_matrix_type           full
_refine_ls_weighting_scheme      calc
_refine_ls_weighting_details     
'w=1/[σ²(Fo²)+(0.0528P)²+0.4583P] where P=(Fo²+2Fc²)/3'
_atom_sites_solution_primary     direct
_atom_sites_solution_secondary   direct
_atom_sites_solution_hydrogens   difmap
_refine_ls_hydrogen_treatment    refall
_refine_ls_extinction_method     none
_refine_ls_extinction_coef       .
_refine_ls_abs_structure_details 
;
 Flack x determined using 1273 quotients [(I+)-(I-)]/[(I+)+(I-)]
 (Parsons, Flack and Wagner, Acta Cryst. B69 (2013) 249-259).
;
_refine_ls_abs_structure_Flack   0.1(2)
_chemical_absolute_configuration R,R,R
_refine_ls_number_reflns         3045
_refine_ls_number_parameters     279
_refine_ls_number_restraints     1
_refine_ls_R_factor_all          0.0335
_refine_ls_R_factor_gt           0.0325
_refine_ls_wR_factor_ref         0.0888
_refine_ls_wR_factor_gt          0.0879
_refine_ls_goodness_of_fit_ref   1.067
_refine_ls_restrained_S_all      1.067
_refine_ls_shift/su_max          0.000
_refine_ls_shift/su_mean         0.000

loop_
_atom_site_label
_atom_site_type_symbol
_atom_site_fract_x
_atom_site_fract_y
_atom_site_fract_z
_atom_site_U_iso_or_equiv
_atom_site_adp_type
_atom_site_occupancy
_atom_site_site_symmetry_order
_atom_site_calc_flag
_atom_site_refinement_flags_posn
_atom_site_refinement_flags_adp
_atom_site_refinement_flags_occupancy
_atom_site_disorder_assembly
_atom_site_disorder_group
O1 O 0.49790(9) 0.7426(3) 0.86715(8) 0.0381(4) Uani 1 1 d . . . . .
O2 O 0.40874(8) 0.4459(3) 0.72383(8) 0.0358(3) Uani 1 1 d . . . . .
C1 C 0.42280(12) 0.6952(4) 0.88130(11) 0.0343(4) Uani 1 1 d . . . . .
C2 C 0.38271(15) 0.8455(5) 0.92355(13) 0.0438(5) Uani 1 1 d . . . . .
C3 C 0.30477(15) 0.7723(5) 0.92955(13) 0.0486(6) Uani 1 1 d . . . . .
C4 C 0.26899(14) 0.5583(5) 0.89638(13) 0.0449(6) Uani 1 1 d . . . . .
C5 C 0.31056(12) 0.4086(4) 0.85495(12) 0.0371(5) Uani 1 1 d . . . . .
C6 C 0.38788(12) 0.4796(4) 0.84825(11) 0.0315(4) Uani 1 1 d . . . . .
C7 C 0.44406(12) 0.3770(4) 0.80172(11) 0.0317(4) Uani 1 1 d . . . . .
C8 C 0.52513(12) 0.5096(4) 0.83922(12) 0.0354(5) Uani 1 1 d . . . . .
C9 C 0.57937(14) 0.5678(5) 0.78381(14) 0.0472(6) Uani 1 1 d . . . . .
C10 C 0.53147(16) 0.6323(5) 0.70275(14) 0.0477(6) Uani 1 1 d . . . . .
C11 C 0.46511(13) 0.4429(4) 0.67401(12) 0.0376(5) Uani 1 1 d . . . . .
C12 C 0.57158(14) 0.3706(5) 0.90993(14) 0.0452(6) Uani 1 1 d . . . . .
C13 C 0.41326(14) 0.4853(4) 0.59458(13) 0.0410(5) Uani 1 1 d . . . . .
C14 C 0.40579(13) 0.3246(4) 0.53791(13) 0.0390(5) Uani 1 1 d . . . . .
C15 C 0.35352(12) 0.3408(4) 0.45912(12) 0.0365(4) Uani 1 1 d . . . . .
C16 C 0.35794(15) 0.1558(4) 0.40625(13) 0.0429(5) Uani 1 1 d . . . . .
C17 C 0.30849(16) 0.1588(5) 0.33229(14) 0.0481(6) Uani 1 1 d . . . . .
C18 C 0.25354(14) 0.3475(5) 0.30896(14) 0.0463(5) Uani 1 1 d . . . . .
C19 C 0.24800(15) 0.5334(5) 0.36022(14) 0.0467(5) Uani 1 1 d . . . . .
C20 C 0.29763(14) 0.5298(5) 0.43466(13) 0.0434(5) Uani 1 1 d . . . . .
H2 H 0.4098(17) 0.993(7) 0.9480(17) 0.058(8) Uiso 1 1 d . . . . .
H3 H 0.2746(18) 0.881(7) 0.9584(18) 0.064(8) Uiso 1 1 d . . . . .
H4 H 0.2136(16) 0.510(5) 0.9019(14) 0.042(6) Uiso 1 1 d . . . . .
H5 H 0.2845(17) 0.254(6) 0.8291(16) 0.052(7) Uiso 1 1 d . . . . .
H7 H 0.4524(13) 0.197(5) 0.8058(12) 0.028(5) Uiso 1 1 d . . . . .
H9A H 0.6187(19) 0.701(7) 0.8077(17) 0.063(9) Uiso 1 1 d . . . . .
H9B H 0.6150(19) 0.416(7) 0.7801(17) 0.061(8) Uiso 1 1 d . . . . .
H11 H 0.4924(15) 0.280(5) 0.6754(15) 0.044(7) Uiso 1 1 d . . . . .
H10A H 0.5039(16) 0.788(6) 0.7019(15) 0.046(7) Uiso 1 1 d . . . . .
H10B H 0.5671(17) 0.623(5) 0.6677(16) 0.052(8) Uiso 1 1 d . . . . .
H13 H 0.3827(16) 0.641(6) 0.5862(14) 0.044(7) Uiso 1 1 d . . . . .
H12A H 0.5860(16) 0.204(6) 0.8953(15) 0.045(7) Uiso 1 1 d . . . . .
H12B H 0.6238(19) 0.452(6) 0.9334(17) 0.060(8) Uiso 1 1 d . . . . .
H12C H 0.5358(18) 0.349(6) 0.9458(17) 0.059(8) Uiso 1 1 d . . . . .
H14 H 0.4390(16) 0.173(6) 0.5501(16) 0.052(7) Uiso 1 1 d . . . . .
H16 H 0.3937(16) 0.015(6) 0.4240(15) 0.046(7) Uiso 1 1 d . . . . .
H17 H 0.3128(17) 0.022(7) 0.2984(16) 0.055(8) Uiso 1 1 d . . . . .
H18 H 0.2170(16) 0.348(6) 0.2582(16) 0.048(7) Uiso 1 1 d . . . . .
H19 H 0.2114(17) 0.657(6) 0.3437(16) 0.055(8) Uiso 1 1 d . . . . .
H20 H 0.2921(17) 0.656(6) 0.4703(17) 0.054(8) Uiso 1 1 d . . . . .


_geom_special_details            
;
 All esds (except the esd in the dihedral angle between two l.s. planes)
 are estimated using the full covariance matrix.  The cell esds are taken
 into account individually in the estimation of esds in distances, angles
 and torsion angles; correlations between esds in cell parameters are only
 used when they are defined by crystal symmetry.  An approximate (isotropic)
 treatment of cell esds is used for estimating esds involving l.s. planes.
;

loop_
_geom_bond_atom_site_label_1
_geom_bond_atom_site_label_2
_geom_bond_distance
_geom_bond_site_symmetry_2
_geom_bond_publ_flag
O1 C1 1.363(2) . ?
O1 C8 1.478(2) . ?
O2 C7 1.425(2) . ?
O2 C11 1.438(2) . ?
C1 C6 1.384(3) . ?
C1 C2 1.389(3) . ?
C2 C3 1.392(4) . ?
C2 H2 0.97(3) . ?
C3 C4 1.383(4) . ?
C3 H3 1.00(3) . ?
C4 C5 1.392(3) . ?
C4 H4 0.99(3) . ?
C5 C6 1.382(3) . ?
C5 H5 1.01(3) . ?
C6 C7 1.500(3) . ?
C7 C8 1.544(3) . ?
C7 H7 1.00(3) . ?
C8 C12 1.519(3) . ?
C8 C9 1.523(3) . ?
C9 C10 1.519(4) . ?
C9 H9A 1.01(3) . ?
C9 H9B 1.04(4) . ?
C10 C11 1.517(3) . ?
C10 H10A 0.97(3) . ?
C10 H10B 0.96(3) . ?
C11 C13 1.494(3) . ?
C11 H11 1.00(3) . ?
C12 H12A 0.99(3) . ?
C12 H12B 0.98(3) . ?
C12 H12C 0.98(3) . ?
C13 C14 1.322(3) . ?
C13 H13 0.99(3) . ?
C14 C15 1.471(3) . ?
C14 H14 1.00(3) . ?
C15 C20 1.393(3) . ?
C15 C16 1.396(3) . ?
C16 C17 1.381(3) . ?
C16 H16 0.98(3) . ?
C17 C18 1.380(4) . ?
C17 H17 0.98(3) . ?
C18 C19 1.384(4) . ?
C18 H18 0.97(3) . ?
C19 C20 1.389(3) . ?
C19 H19 0.91(3) . ?
C20 H20 0.95(3) . ?

loop_
_geom_angle_atom_site_label_1
_geom_angle_atom_site_label_2
_geom_angle_atom_site_label_3
_geom_angle
_geom_angle_site_symmetry_1
_geom_angle_site_symmetry_3
_geom_angle_publ_flag
C1 O1 C8 105.57(15) . . ?
C7 O2 C11 114.53(15) . . ?
O1 C1 C6 113.50(17) . . ?
O1 C1 C2 124.8(2) . . ?
C6 C1 C2 121.7(2) . . ?
C1 C2 C3 116.8(2) . . ?
C1 C2 H2 119.9(18) . . ?
C3 C2 H2 123.3(18) . . ?
C4 C3 C2 122.0(2) . . ?
C4 C3 H3 120.2(19) . . ?
C2 C3 H3 117.7(19) . . ?
C3 C4 C5 120.3(2) . . ?
C3 C4 H4 120.4(16) . . ?
C5 C4 H4 119.3(16) . . ?
C6 C5 C4 118.3(2) . . ?
C6 C5 H5 120.6(16) . . ?
C4 C5 H5 121.1(17) . . ?
C5 C6 C1 120.83(19) . . ?
C5 C6 C7 131.5(2) . . ?
C1 C6 C7 107.27(17) . . ?
O2 C7 C6 105.56(15) . . ?
O2 C7 C8 114.72(16) . . ?
C6 C7 C8 100.72(16) . . ?
O2 C7 H7 110.6(13) . . ?
C6 C7 H7 115.1(13) . . ?
C8 C7 H7 109.9(13) . . ?
O1 C8 C12 106.89(16) . . ?
O1 C8 C9 108.37(19) . . ?
C12 C8 C9 112.04(18) . . ?
O1 C8 C7 103.97(15) . . ?
C12 C8 C7 110.48(18) . . ?
C9 C8 C7 114.48(17) . . ?
C10 C9 C8 113.74(18) . . ?
C10 C9 H9A 112.4(18) . . ?
C8 C9 H9A 107.9(18) . . ?
C10 C9 H9B 108.0(17) . . ?
C8 C9 H9B 108.3(17) . . ?
H9A C9 H9B 106(2) . . ?
C11 C10 C9 110.1(2) . . ?
C11 C10 H10A 106.7(16) . . ?
C9 C10 H10A 111.3(16) . . ?
C11 C10 H10B 105.1(17) . . ?
C9 C10 H10B 109.6(16) . . ?
H10A C10 H10B 114(2) . . ?
O2 C11 C13 105.26(16) . . ?
O2 C11 C10 108.52(17) . . ?
C13 C11 C10 115.44(19) . . ?
O2 C11 H11 111.0(15) . . ?
C13 C11 H11 108.8(15) . . ?
C10 C11 H11 107.8(15) . . ?
C8 C12 H12A 110.5(15) . . ?
C8 C12 H12B 110.9(19) . . ?
H12A C12 H12B 106(2) . . ?
C8 C12 H12C 109.2(18) . . ?
H12A C12 H12C 107(3) . . ?
H12B C12 H12C 113(3) . . ?
C14 C13 C11 123.3(2) . . ?
C14 C13 H13 120.4(15) . . ?
C11 C13 H13 116.3(15) . . ?
C13 C14 C15 128.0(2) . . ?
C13 C14 H14 116.2(17) . . ?
C15 C14 H14 115.8(17) . . ?
C20 C15 C16 117.7(2) . . ?
C20 C15 C14 123.2(2) . . ?
C16 C15 C14 119.0(2) . . ?
C17 C16 C15 121.3(2) . . ?
C17 C16 H16 120.0(16) . . ?
C15 C16 H16 118.5(16) . . ?
C18 C17 C16 120.3(2) . . ?
C18 C17 H17 122.0(17) . . ?
C16 C17 H17 117.7(17) . . ?
C17 C18 C19 119.6(2) . . ?
C17 C18 H18 121.1(18) . . ?
C19 C18 H18 119.3(18) . . ?
C18 C19 C20 120.1(2) . . ?
C18 C19 H19 118.3(18) . . ?
C20 C19 H19 121.6(18) . . ?
C19 C20 C15 121.0(2) . . ?
C19 C20 H20 119.6(17) . . ?
C15 C20 H20 119.3(17) . . ?

_refine_diff_density_max         0.189
_refine_diff_density_min         -0.106
_refine_diff_density_rms         0.024



