# Electronic Supplementary Material (ESI) for ChemComm.
# This journal is © The Royal Society of Chemistry 2019

####################################################################### 
# 
# This file contains crystal structure data downloaded from the 
# Cambridge Structural Database (CSD) hosted by the Cambridge 
# Crystallographic Data Centre (CCDC).
# 
# Full information about CCDC data access policies and citation 
# guidelines are available at http://www.ccdc.cam.ac.uk/access/V1 
# 
# Audit and citation data items may have been added by the CCDC. 
# Please retain this information to preserve the provenance of 
# this file and to allow appropriate attribution of the data. 
# 
#######################################################################

data_SP
_audit_block_doi                 10.5517/ccdc.csd.cc20zrsk
_database_code_depnum_ccdc_archive 'CCDC 1876609'
loop_
_audit_author_name
_audit_author_address
'Peng Shi'
;Soochow University
China
;
_audit_update_record             
;
2018-11-01 deposited with the CCDC.	2019-08-08 downloaded from the CCDC.
;

_audit_creation_method           SHELXL-2017/1
_shelx_SHELXL_version_number     2017/1
_chemical_name_systematic        ?
_chemical_name_common            ?
_chemical_melting_point          ?
_chemical_formula_moiety         'C25 H22 N2 O'
_chemical_formula_sum            'C25 H22 N2 O'
_chemical_formula_weight         366.44

loop_
_atom_type_symbol
_atom_type_description
_atom_type_scat_dispersion_real
_atom_type_scat_dispersion_imag
_atom_type_scat_source
C C 0.0033 0.0016 'International Tables Vol C Tables 4.2.6.8 and 6.1.1.4'
H H 0.0000 0.0000 'International Tables Vol C Tables 4.2.6.8 and 6.1.1.4'
N N 0.0061 0.0033 'International Tables Vol C Tables 4.2.6.8 and 6.1.1.4'
O O 0.0106 0.0060 'International Tables Vol C Tables 4.2.6.8 and 6.1.1.4'

_space_group_crystal_system      monoclinic
_space_group_IT_number           4
_space_group_name_H-M_alt        'P 21'
_space_group_name_Hall           'P 2yb'

_shelx_space_group_comment       
;
The symmetry employed for this shelxl refinement is uniquely defined
by the following loop, which should always be used as a source of
symmetry information in preference to the above space-group names.
They are only intended as comments.
;

loop_
_space_group_symop_operation_xyz
'x, y, z'
'-x, y+1/2, -z'

_cell_length_a                   9.9877(13)
_cell_length_b                   9.5433(12)
_cell_length_c                   10.2039(13)
_cell_angle_alpha                90
_cell_angle_beta                 92.235(4)
_cell_angle_gamma                90
_cell_volume                     971.9(2)
_cell_formula_units_Z            2
_cell_measurement_temperature    210(2)
_cell_measurement_reflns_used    4237
_cell_measurement_theta_min      2.80
_cell_measurement_theta_max      22.54

_exptl_crystal_description       ??block??
_exptl_crystal_colour            yelow
_exptl_crystal_density_meas      ?
_exptl_crystal_density_method    ?
_exptl_crystal_density_diffrn    1.252
_exptl_crystal_F_000             388
_exptl_transmission_factor_min   ?
_exptl_transmission_factor_max   ?
_exptl_crystal_size_max          0.3
_exptl_crystal_size_mid          0.25
_exptl_crystal_size_min          0.15
_exptl_absorpt_coefficient_mu    0.077
_shelx_estimated_absorpt_T_min   ?
_shelx_estimated_absorpt_T_max   ?
_exptl_absorpt_correction_type   MULTI-SCAN
_exptl_absorpt_correction_T_min  0.4946
_exptl_absorpt_correction_T_max  0.7457
_exptl_absorpt_process_details   
'SADABS-2008/1 - Bruker AXS area detector scaling and absorption correction'
_exptl_absorpt_special_details   ?
_diffrn_ambient_temperature      210(2)
_diffrn_radiation_wavelength     0.71073
_diffrn_radiation_type           MoK\a
_diffrn_source                   ?
_diffrn_measurement_device_type  'Bruker APEX-II CCD'
_diffrn_measurement_method       'φ and ω scans'
_diffrn_detector_area_resol_mean ?
_diffrn_reflns_number            25713
_diffrn_reflns_av_unetI/netI     0.0952
_diffrn_reflns_av_R_equivalents  0.1559
_diffrn_reflns_limit_h_min       -11
_diffrn_reflns_limit_h_max       11
_diffrn_reflns_limit_k_min       -11
_diffrn_reflns_limit_k_max       11
_diffrn_reflns_limit_l_min       -12
_diffrn_reflns_limit_l_max       12
_diffrn_reflns_theta_min         2.800
_diffrn_reflns_theta_max         24.992
_diffrn_reflns_theta_full        24.992
_diffrn_measured_fraction_theta_max 0.999
_diffrn_measured_fraction_theta_full 0.999
_diffrn_reflns_Laue_measured_fraction_max 0.999
_diffrn_reflns_Laue_measured_fraction_full 0.999
_diffrn_reflns_point_group_measured_fraction_max 0.999
_diffrn_reflns_point_group_measured_fraction_full 0.999
_reflns_number_total             3429
_reflns_number_gt                2353
_reflns_threshold_expression     'I > 2σ(I)'
_reflns_Friedel_coverage         0.877
_reflns_Friedel_fraction_max     1.000
_reflns_Friedel_fraction_full    1.000

_reflns_special_details          
;
 Reflections were merged by SHELXL according to the crystal
 class for the calculation of statistics and refinement.
 
 _reflns_Friedel_fraction is defined as the number of unique
 Friedel pairs measured divided by the number that would be
 possible theoretically, ignoring centric projections and
 systematic absences.
;

_computing_data_collection       'Bruker APEX2'
_computing_cell_refinement       'Bruker SAINT'
_computing_data_reduction        'Bruker SAINT'
_computing_structure_solution    'SHELXT 2014/5 (Sheldrick, 2014)'
_computing_structure_refinement  'SHELXL-2017/1 (Sheldrick, 2017)'
_computing_molecular_graphics    'Bruker SHELXTL'
_computing_publication_material  'Bruker SHELXTL'
_refine_special_details          ?
_refine_ls_structure_factor_coef Fsqd
_refine_ls_matrix_type           full
_refine_ls_weighting_scheme      calc
_refine_ls_weighting_details     
'w=1/[σ²(Fo²)+(0.0388P)²+0.0993P] where P=(Fo²+2Fc²)/3'
_atom_sites_solution_primary     ?
_atom_sites_solution_secondary   ?
_atom_sites_solution_hydrogens   geom
_refine_ls_hydrogen_treatment    constr
_refine_ls_extinction_method     none
_refine_ls_extinction_coef       .
_refine_ls_abs_structure_details 
;
 Flack x determined using 843 quotients [(I+)-(I-)]/[(I+)+(I-)]
 (Parsons, Flack and Wagner, Acta Cryst. B69 (2013) 249-259).
;
_refine_ls_abs_structure_Flack   1.6(10)
_chemical_absolute_configuration ?
_refine_ls_number_reflns         3429
_refine_ls_number_parameters     253
_refine_ls_number_restraints     1
_refine_ls_R_factor_all          0.1053
_refine_ls_R_factor_gt           0.0579
_refine_ls_wR_factor_ref         0.1094
_refine_ls_wR_factor_gt          0.0975
_refine_ls_goodness_of_fit_ref   1.056
_refine_ls_restrained_S_all      1.056
_refine_ls_shift/su_max          0.000
_refine_ls_shift/su_mean         0.000

loop_
_atom_site_label
_atom_site_type_symbol
_atom_site_fract_x
_atom_site_fract_y
_atom_site_fract_z
_atom_site_U_iso_or_equiv
_atom_site_adp_type
_atom_site_occupancy
_atom_site_site_symmetry_order
_atom_site_calc_flag
_atom_site_refinement_flags_posn
_atom_site_refinement_flags_adp
_atom_site_refinement_flags_occupancy
_atom_site_disorder_assembly
_atom_site_disorder_group
O1 O 0.7742(3) 0.7539(3) 0.8350(3) 0.0409(9) Uani 1 1 d . . . . .
N2 N 0.8736(3) 0.3627(3) 0.9080(3) 0.0255(9) Uani 1 1 d . . . . .
N1 N 0.7564(3) 0.5466(4) 0.7310(3) 0.0256(9) Uani 1 1 d . . . . .
C8 C 0.8641(4) 0.5639(5) 0.5152(4) 0.0275(11) Uani 1 1 d . . . . .
C21 C 0.7172(5) 0.6404(5) 0.8211(4) 0.0273(11) Uani 1 1 d . . . . .
C20 C 0.7777(4) 0.3096(4) 0.8228(4) 0.0243(11) Uani 1 1 d . . . . .
C13 C 0.7130(4) 0.4024(4) 0.7322(4) 0.0255(11) Uani 1 1 d . . . . .
C4 C 0.8169(4) 0.6732(5) 0.3008(4) 0.0326(13) Uani 1 1 d . . . . .
C9 C 0.8192(4) 0.6819(5) 0.4401(4) 0.0269(11) Uani 1 1 d . . . . .
C12 C 0.6137(5) 0.3557(5) 0.6492(5) 0.0356(12) Uani 1 1 d . . . . .
H12A H 0.570175 0.417773 0.591611 0.043 Uiso 1 1 calc R U . . .
C11 C 0.8820(4) 0.5708(5) 0.6621(4) 0.0301(11) Uani 1 1 d . . . . .
H11A H 0.947558 0.501148 0.690757 0.036 Uiso 1 1 calc R U . . .
H11B H 0.917318 0.662219 0.686550 0.036 Uiso 1 1 calc R U . . .
C19 C 0.9335(5) 0.2742(5) 0.9892(4) 0.0331(12) Uani 1 1 d . . . . .
H19A H 0.999612 0.308966 1.047174 0.040 Uiso 1 1 calc R U . . .
C15 C 0.6386(5) 0.1218(5) 0.7321(5) 0.0389(13) Uani 1 1 d . . . . .
H15A H 0.613288 0.028034 0.730511 0.047 Uiso 1 1 calc R U . . .
C5 C 0.8534(5) 0.5459(6) 0.2414(5) 0.0423(13) Uani 1 1 d . . . . .
H5A H 0.852144 0.539497 0.150421 0.051 Uiso 1 1 calc R U . . .
C18 C 0.9045(5) 0.1302(5) 0.9945(5) 0.0381(13) Uani 1 1 d . . . . .
H18A H 0.950278 0.072178 1.054209 0.046 Uiso 1 1 calc R U . . .
C16 C 0.7416(5) 0.1668(4) 0.8203(4) 0.0290(12) Uani 1 1 d . . . . .
C17 C 0.8085(5) 0.0779(5) 0.9108(5) 0.0382(13) Uani 1 1 d . . . . .
H17A H 0.786857 -0.016815 0.913382 0.046 Uiso 1 1 calc R U . . .
C7 C 0.8972(5) 0.4430(5) 0.4512(5) 0.0393(13) Uani 1 1 d . . . . .
H7A H 0.925093 0.365331 0.500133 0.047 Uiso 1 1 calc R U . . .
C22 C 0.6004(5) 0.6030(5) 0.9039(4) 0.0349(12) Uani 1 1 d . . . . .
H22A H 0.633916 0.557292 0.983464 0.042 Uiso 1 1 calc R U . . .
H22B H 0.543235 0.536740 0.856073 0.042 Uiso 1 1 calc R U . . .
C14 C 0.5761(5) 0.2139(5) 0.6499(5) 0.0405(13) Uani 1 1 d . . . . .
H14A H 0.507400 0.182978 0.592972 0.049 Uiso 1 1 calc R U . . .
C3 C 0.7812(5) 0.7919(6) 0.2257(5) 0.0417(13) Uani 1 1 d . . . . .
H3A H 0.780965 0.786854 0.134640 0.050 Uiso 1 1 calc R U . . .
C24 C 0.4332(5) 0.7892(5) 0.8325(5) 0.0454(14) Uani 1 1 d . . . . .
H24A H 0.373523 0.858772 0.855989 0.055 Uiso 1 1 calc R U . . .
C10 C 0.7816(5) 0.8110(5) 0.4976(5) 0.0349(12) Uani 1 1 d . . . . .
H10A H 0.780835 0.819265 0.588403 0.042 Uiso 1 1 calc R U . . .
C6 C 0.8900(5) 0.4335(6) 0.3140(5) 0.0483(14) Uani 1 1 d . . . . .
H6A H 0.910512 0.349522 0.273184 0.058 Uiso 1 1 calc R U . . .
C23 C 0.5179(5) 0.7288(5) 0.9402(4) 0.0408(13) Uani 1 1 d . . . . .
H23A H 0.460556 0.702139 1.010599 0.049 Uiso 1 1 calc R U . . .
H23B H 0.578129 0.801173 0.973898 0.049 Uiso 1 1 calc R U . . .
C2 C 0.7473(5) 0.9129(6) 0.2837(5) 0.0468(14) Uani 1 1 d . . . . .
H2A H 0.724168 0.990500 0.232586 0.056 Uiso 1 1 calc R U . . .
C1 C 0.7468(5) 0.9226(5) 0.4203(5) 0.0450(14) Uani 1 1 d . . . . .
H1A H 0.722202 1.006452 0.459106 0.054 Uiso 1 1 calc R U . . .
C25 C 0.4320(5) 0.7568(6) 0.7098(5) 0.0525(15) Uani 1 1 d . . . . .
H25A H 0.489496 0.687893 0.680490 0.063 Uiso 1 1 calc R U . . .
H25B H 0.373767 0.802367 0.650664 0.063 Uiso 1 1 calc R U . . .


_geom_special_details            
;
 All esds (except the esd in the dihedral angle between two l.s. planes)
 are estimated using the full covariance matrix.  The cell esds are taken
 into account individually in the estimation of esds in distances, angles
 and torsion angles; correlations between esds in cell parameters are only
 used when they are defined by crystal symmetry.  An approximate (isotropic)
 treatment of cell esds is used for estimating esds involving l.s. planes.
;

loop_
_geom_bond_atom_site_label_1
_geom_bond_atom_site_label_2
_geom_bond_distance
_geom_bond_site_symmetry_2
_geom_bond_publ_flag
O1 C21 1.229(5) . ?
N2 C19 1.311(5) . ?
N2 C20 1.366(5) . ?
N1 C21 1.352(5) . ?
N1 C13 1.443(5) . ?
N1 C11 1.480(5) . ?
C8 C7 1.373(6) . ?
C8 C9 1.424(6) . ?
C8 C11 1.503(6) . ?
C21 C22 1.510(6) . ?
C20 C16 1.410(6) . ?
C20 C13 1.417(6) . ?
C13 C12 1.354(6) . ?
C4 C3 1.406(6) . ?
C4 C5 1.412(6) . ?
C4 C9 1.423(6) . ?
C9 C10 1.421(6) . ?
C12 C14 1.404(7) . ?
C12 H12A 0.9300 . ?
C11 H11A 0.9700 . ?
C11 H11B 0.9700 . ?
C19 C18 1.405(6) . ?
C19 H19A 0.9300 . ?
C15 C14 1.351(7) . ?
C15 C16 1.407(6) . ?
C15 H15A 0.9300 . ?
C5 C6 1.346(7) . ?
C5 H5A 0.9300 . ?
C18 C17 1.355(6) . ?
C18 H18A 0.9300 . ?
C16 C17 1.404(6) . ?
C17 H17A 0.9300 . ?
C7 C6 1.402(7) . ?
C7 H7A 0.9300 . ?
C22 C23 1.511(6) . ?
C22 H22A 0.9700 . ?
C22 H22B 0.9700 . ?
C14 H14A 0.9300 . ?
C3 C2 1.347(7) . ?
C3 H3A 0.9300 . ?
C24 C25 1.289(6) . ?
C24 C23 1.477(7) . ?
C24 H24A 0.9300 . ?
C10 C1 1.362(7) . ?
C10 H10A 0.9300 . ?
C6 H6A 0.9300 . ?
C23 H23A 0.9700 . ?
C23 H23B 0.9700 . ?
C2 C1 1.397(7) . ?
C2 H2A 0.9300 . ?
C1 H1A 0.9300 . ?
C25 H25A 0.9300 . ?
C25 H25B 0.9300 . ?

loop_
_geom_angle_atom_site_label_1
_geom_angle_atom_site_label_2
_geom_angle_atom_site_label_3
_geom_angle
_geom_angle_site_symmetry_1
_geom_angle_site_symmetry_3
_geom_angle_publ_flag
C19 N2 C20 117.1(4) . . ?
C21 N1 C13 122.1(4) . . ?
C21 N1 C11 119.5(4) . . ?
C13 N1 C11 114.4(3) . . ?
C7 C8 C9 119.0(4) . . ?
C7 C8 C11 119.3(4) . . ?
C9 C8 C11 121.7(4) . . ?
O1 C21 N1 121.1(4) . . ?
O1 C21 C22 120.6(4) . . ?
N1 C21 C22 118.3(4) . . ?
N2 C20 C16 122.8(4) . . ?
N2 C20 C13 118.3(4) . . ?
C16 C20 C13 118.8(4) . . ?
C12 C13 C20 120.4(4) . . ?
C12 C13 N1 121.4(4) . . ?
C20 C13 N1 118.1(4) . . ?
C3 C4 C5 121.6(4) . . ?
C3 C4 C9 119.4(4) . . ?
C5 C4 C9 118.9(4) . . ?
C10 C9 C4 118.0(4) . . ?
C10 C9 C8 123.0(4) . . ?
C4 C9 C8 119.0(4) . . ?
C13 C12 C14 120.2(5) . . ?
C13 C12 H12A 119.9 . . ?
C14 C12 H12A 119.9 . . ?
N1 C11 C8 113.4(3) . . ?
N1 C11 H11A 108.9 . . ?
C8 C11 H11A 108.9 . . ?
N1 C11 H11B 108.9 . . ?
C8 C11 H11B 108.9 . . ?
H11A C11 H11B 107.7 . . ?
N2 C19 C18 124.3(5) . . ?
N2 C19 H19A 117.8 . . ?
C18 C19 H19A 117.8 . . ?
C14 C15 C16 120.5(5) . . ?
C14 C15 H15A 119.8 . . ?
C16 C15 H15A 119.8 . . ?
C6 C5 C4 121.2(4) . . ?
C6 C5 H5A 119.4 . . ?
C4 C5 H5A 119.4 . . ?
C17 C18 C19 118.6(5) . . ?
C17 C18 H18A 120.7 . . ?
C19 C18 H18A 120.7 . . ?
C17 C16 C15 123.6(4) . . ?
C17 C16 C20 117.2(4) . . ?
C15 C16 C20 119.1(4) . . ?
C18 C17 C16 119.9(4) . . ?
C18 C17 H17A 120.0 . . ?
C16 C17 H17A 120.0 . . ?
C8 C7 C6 121.7(5) . . ?
C8 C7 H7A 119.2 . . ?
C6 C7 H7A 119.2 . . ?
C21 C22 C23 112.9(4) . . ?
C21 C22 H22A 109.0 . . ?
C23 C22 H22A 109.0 . . ?
C21 C22 H22B 109.0 . . ?
C23 C22 H22B 109.0 . . ?
H22A C22 H22B 107.8 . . ?
C15 C14 C12 120.9(5) . . ?
C15 C14 H14A 119.6 . . ?
C12 C14 H14A 119.6 . . ?
C2 C3 C4 120.9(5) . . ?
C2 C3 H3A 119.5 . . ?
C4 C3 H3A 119.5 . . ?
C25 C24 C23 127.7(5) . . ?
C25 C24 H24A 116.1 . . ?
C23 C24 H24A 116.1 . . ?
C1 C10 C9 120.3(4) . . ?
C1 C10 H10A 119.9 . . ?
C9 C10 H10A 119.9 . . ?
C5 C6 C7 120.1(5) . . ?
C5 C6 H6A 120.0 . . ?
C7 C6 H6A 120.0 . . ?
C24 C23 C22 115.4(4) . . ?
C24 C23 H23A 108.4 . . ?
C22 C23 H23A 108.4 . . ?
C24 C23 H23B 108.4 . . ?
C22 C23 H23B 108.4 . . ?
H23A C23 H23B 107.5 . . ?
C3 C2 C1 120.4(5) . . ?
C3 C2 H2A 119.8 . . ?
C1 C2 H2A 119.8 . . ?
C10 C1 C2 121.0(5) . . ?
C10 C1 H1A 119.5 . . ?
C2 C1 H1A 119.5 . . ?
C24 C25 H25A 120.0 . . ?
C24 C25 H25B 120.0 . . ?
H25A C25 H25B 120.0 . . ?

_refine_diff_density_max         0.163
_refine_diff_density_min         -0.198
_refine_diff_density_rms         0.042

