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{"sheet":"daphnia_summary_ko_differential","index":0,"n_rows":254,"n_cols":9,"rows_kept":254,"cut":false,"hidden":false,"merged":[],"flags":["formulas_cached_only"]}
["KO","Annotation","Normal_vs_LowAgNPs(logFC)","Normal_vs_HighAgNPs(logFC)","Normal_vs_TLIAgNPs(logFC)","LowAgNPs_vs_HighAgNPs(logFC)","LowAgNPs_vs_TLAgNPs(logFC)","Normal_vs_FLAgNPs(logFC)","FLAgNPs_vs_TLAgNPs(logFC)"]
["K00019","E1.1.1.30, bdh; 3-hydroxybutyrate dehydrogenase [EC:1.1.1.30]",7.582111528,7.865778559,7.408905479,"NOT","NOT",8.350570175,"NOT"]
["K00029","E1.1.1.40, maeB; malate dehydrogenase (oxaloacetate-decarboxylating)(NADP+) [EC:1.1.1.40]","NOT",-1.214589414,"NOT","NOT","NOT",-1.026073169,"NOT"]
["K00052","leuB, IMDH; 3-isopropylmalate dehydrogenase [EC:1.1.1.85]","NOT",4.723502761,"NOT",4.723502761,"NOT","NOT","NOT"]
["K00058","serA, PHGDH; D-3-phosphoglycerate dehydrogenase / 2-oxoglutarate reductase [EC:1.1.1.95 1.1.1.399]",-1.076433926,-1.262390331,"NOT","NOT",1.282388081,-7.802894899,8.008849054]
["K00099","dxr; 1-deoxy-D-xylulose-5-phosphate reductoisomerase [EC:1.1.1.267]","NOT",-6.135684137,"NOT",-6.630280208,"NOT",-6.135684137,6.580732182]
["K00134","GAPDH, gapA; glyceraldehyde 3-phosphate dehydrogenase [EC:1.2.1.12]",-1.392051129,-1.065626054,-1.418526791,"NOT","NOT",-1.014534647,"NOT"]
["K00145","argC; N-acetyl-gamma-glutamyl-phosphate reductase [EC:1.2.1.38]",-6.016082069,-6.016082069,2.547670476,"NOT",8.563752545,-6.016082069,8.563752545]
["K00213","DHCR7; 7-dehydrocholesterol reductase [EC:1.3.1.21]",-3.518593004,-3.431984859,"NOT","NOT",3.009214818,-2.152165091,1.642786905]
["K00222","TM7SF2, ERG24; Delta14-sterol reductase [EC:1.3.1.70]","NOT",1.69218223,"NOT",2.383044928,"NOT","NOT",-1.060654102]
["K00227","SC5DL, ERG3; Delta7-sterol 5-desaturase [EC:1.14.19.20]","NOT",-1.072965492,-1.29780319,"NOT","NOT","NOT","NOT"]
["K00281","GLDC, gcvP; glycine dehydrogenase [EC:1.4.4.2]","NOT","NOT","NOT",1.316623243,1.019284803,"NOT","NOT"]
["K00297","metF, MTHFR; methylenetetrahydrofolate reductase (NADPH) [EC:1.5.1.20]","NOT",-1.48918104,"NOT","NOT","NOT","NOT","NOT"]
["K00362","nirB; nitrite reductase (NADH) large subunit [EC:1.7.1.15]","NOT","NOT","NOT","NOT","NOT",-1.409628534,1.520103834]
["K00368","nirK; nitrite reductase (NO-forming) [EC:1.7.2.1]",3.965507961,"NOT",4.716831425,-3.965507961,"NOT","NOT","NOT"]
["K00405","ccoO; cytochrome c oxidase cbb3-type subunit II","NOT","NOT",5.667060651,"NOT",5.667060651,"NOT",5.667060651]
["K00406","ccoP; cytochrome c oxidase cbb3-type subunit III","NOT","NOT",2.264299679,-6.061432062,"NOT","NOT",7.527492235]
["K00615","E2.2.1.1, tktA, tktB; transketolase [EC:2.2.1.1]","NOT","NOT","NOT","NOT",-1.017200926,"NOT","NOT"]
["K00616","E2.2.1.2, talA, talB; transaldolase [EC:2.2.1.2]","NOT",-2.855086999,"NOT",-2.429545957,"NOT",-2.340602557,2.024981848]
["K00620","argJ; glutamate N-acetyltransferase / amino-acid N-acetyltransferase [EC:2.3.1.35 2.3.1.1]","NOT",-6.881472661,1.210129323,-6.857218694,1.234383289,-6.881472661,8.091601983]
["K00640","cysE; serine O-acetyltransferase [EC:2.3.1.30]",-5.889686555,-5.889686555,1.503957927,"NOT",7.393644481,-5.889686555,7.393644481]
["K00677","lpxA; UDP-N-acetylglucosamine acyltransferase [EC:2.3.1.129]","NOT",-5.588172278,"NOT",-5.890134889,"NOT",-5.588172278,5.465326868]
["K00688","PYG, glgP; glycogen phosphorylase [EC:2.4.1.1]",-1.19627508,"NOT","NOT",1.378096557,"NOT","NOT",-1.104342729]
["K00705","malQ; 4-alpha-glucanotransferase [EC:2.4.1.25]",-1.525857118,-6.558665486,"NOT",-5.032808368,2.310019439,-6.558665486,7.342827807]
["K00796","folP; dihydropteroate synthase [EC:2.5.1.15]","NOT",-7.167943338,2.145083298,-7.94283831,"NOT","NOT",9.313026636]
["K00818","E2.6.1.11, argD; acetylornithine aminotransferase [EC:2.6.1.11]",-1.385110266,-6.916186521,"NOT",-5.531076255,1.850749406,-6.916186521,7.381825661]
["K00830","AGXT; alanine-glyoxylate transaminase / serine-glyoxylate transaminase / serine-pyruvate transaminase [EC:2.6.1.44 2.6.1.45 2.6.1.51]","NOT","NOT","NOT","NOT","NOT",-1.115184542,1.184766851]
["K00832","tyrB; aromatic-amino-acid transaminase [EC:2.6.1.57]","NOT",-7.585178079,1.467460896,-7.429925131,1.622713844,-7.585178079,9.052638975]
["K00863","DAK, TKFC; triose/dihydroxyacetone kinase / FAD-AMP lyase (cyclizing) [EC:2.7.1.28 2.7.1.29 4.6.1.15]","NOT",-1.760538902,"NOT","NOT","NOT",-1.633260584,1.561026822]
["K00866","CKI1; choline kinase [EC:2.7.1.32]","NOT","NOT","NOT","NOT","NOT","NOT","NOT"]
["K00912","lpxK; tetraacyldisaccharide 4'-kinase [EC:2.7.1.130]",5.072876375,"NOT",6.069872582,-5.072876375,"NOT","NOT",6.069872582]
["K00927","PGK, pgk; phosphoglycerate kinase [EC:2.7.2.3]",-1.170001424,"NOT","NOT","NOT",1.161641876,"NOT","NOT"]
["K00928","lysC; aspartate kinase [EC:2.7.2.4]","NOT",-7.50946645,"NOT",-6.524526731,1.568862998,-7.50946645,8.093389729]
["K00962","pnp, PNPT1; polyribonucleotide nucleotidyltransferase [EC:2.7.7.8]","NOT","NOT",-1.161174273,"NOT","NOT","NOT",-1.186446402]
["K00968","PCYT1; choline-phosphate cytidylyltransferase [EC:2.7.7.15]","NOT",-1.023595586,"NOT",-1.294778216,"NOT",-1.198444329,1.41609078]
["K00979","kdsB; 3-deoxy-manno-octulosonate cytidylyltransferase (CMP-KDO synthetase) [EC:2.7.7.38]","NOT","NOT",6.085417184,"NOT",6.085417184,"NOT",6.085417184]
["K01007","pps, ppsA; pyruvate, water dikinase [EC:2.7.9.2]",-1.189759319,-1.17337449,"NOT","NOT","NOT",-1.216830593,"NOT"]
["K01051","E3.1.1.11; pectinesterase [EC:3.1.1.11]",1.053950479,-5.231941365,1.443338475,-6.285891844,"NOT",-5.231941365,6.67527984]
["K01077","E3.1.3.1, phoA, phoB; alkaline phosphatase [EC:3.1.3.1]",-1.02711688,"NOT",-1.10945929,"NOT","NOT","NOT","NOT"]
["K01113","phoD; alkaline phosphatase D [EC:3.1.3.1]","NOT","NOT",1.449614015,"NOT","NOT","NOT",2.287833401]
["K01200","pulA; pullulanase [EC:3.2.1.41]",6.019495197,"NOT",7.368223997,-6.019495197,1.348728799,"NOT",7.368223997]
["K01207","nagZ; beta-N-acetylhexosaminidase [EC:3.2.1.52]",1.341578247,-6.035162673,2.856437877,-7.376740919,1.51485963,-6.035162673,8.89160055]
["K01228","GCS1; mannosyl-oligosaccharide glucosidase [EC:3.2.1.106]","NOT","NOT","NOT","NOT","NOT",-1.300626745,"NOT"]
["K01230","MAN1; mannosyl-oligosaccharide alpha-1,2-mannosidase [EC:3.2.1.113]","NOT",-1.021425612,"NOT","NOT","NOT","NOT",1.356575259]
["K01438","argE; acetylornithine deacetylase [EC:3.5.1.16]","NOT","NOT",7.928357398,"NOT",7.928357398,"NOT",7.928357398]
["K01439","dapE; succinyl-diaminopimelate desuccinylase [EC:3.5.1.18]",1.131969686,-5.43076145,2.413356163,-6.562731136,1.281386477,-5.43076145,7.844117613]
["K01448","amiABC; N-acetylmuramoyl-L-alanine amidase [EC:3.5.1.28]",5.796419048,"NOT",7.38575155,-5.796419048,1.589332503,"NOT",7.38575155]
["K01468","hutI, AMDHD1; imidazolonepropionase [EC:3.5.2.7]","NOT","NOT",1.095285605,"NOT","NOT","NOT",1.142655199]
["K01476","E3.5.3.1, rocF, arg; arginase [EC:3.5.3.1]","NOT","NOT","NOT","NOT","NOT",-1.564265681,1.525526177]
["K01479","hutG; formiminoglutamase [EC:3.5.3.8]","NOT","NOT",7.790291381,"NOT",7.790291381,"NOT",7.790291381]
["K01581","E4.1.1.17, ODC1, speC, speF; ornithine decarboxylase [EC:4.1.1.17]","NOT","NOT","NOT","NOT","NOT",-1.534693941,"NOT"]
["K01589","purK; 5-(carboxyamino)imidazole ribonucleotide synthase [EC:6.3.4.18]","NOT",-2.501441589,"NOT",-1.803996554,1.680450396,-6.779367007,7.762372368]
["K01617","dmpH, xylI, nahK; 2-oxo-3-hexenedioate decarboxylase [EC:4.1.1.77]",3.982957669,"NOT",6.059022222,-3.982957669,2.076064553,"NOT",6.059022222]
["K01625","eda; 2-dehydro-3-deoxyphosphogluconate aldolase / (4S)-4-hydroxy-2-oxoglutarate aldolase [EC:4.1.2.14 4.1.3.42]",-1.010803233,-8.15929766,1.615025731,-7.148494427,2.625828964,-8.15929766,9.77432339]
["K01689","ENO, eno; enolase [EC:4.2.1.11]",-1.331556483,"NOT",-1.371285385,1.693823403,"NOT","NOT",-1.46976699]
["K01712","hutU, UROC1; urocanate hydratase [EC:4.2.1.49]",-1.096107875,"NOT","NOT","NOT","NOT",-7.285223336,6.908561939]
["K01738","cysK; cysteine synthase [EC:2.5.1.47]",5.810850895,"NOT","NOT",-5.810850895,-5.810850895,"NOT","NOT"]
["K01745","hutH, HAL; histidine ammonia-lyase [EC:4.3.1.3]","NOT",-1.090051702,1.394948228,"NOT",2.038226696,"NOT",2.298019924]
["K01770","ispF; 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase [EC:4.6.1.12]","NOT","NOT",5.802754389,"NOT",5.802754389,"NOT",5.802754389]
["K01785","galM, GALM; aldose 1-epimerase [EC:5.1.3.3]","NOT","NOT","NOT",-1.077599745,"NOT","NOT",1.352816631]
["K01796","E5.1.99.4, AMACR, mcr; alpha-methylacyl-CoA racemase [EC:5.1.99.4]","NOT","NOT",1.301481313,"NOT",1.306769845,"NOT",1.696369188]
["K01807","rpiA; ribose 5-phosphate isomerase A [EC:5.3.1.6]",-1.035450452,-2.673415409,"NOT",-1.637964957,1.211622357,-1.291798822,1.467970727]
["K01814","hisA; phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase [EC:5.3.1.16]","NOT",-4.228225842,2.944725329,-5.016657588,2.156293583,"NOT",7.172951171]
["K01919","gshA; glutamate--cysteine ligase [EC:6.3.2.2]",2.061996169,"NOT",3.173012753,-6.818652599,"NOT","NOT",7.929669183]
["K01920","gshB; glutathione synthase [EC:6.3.2.3]",1.124770242,"NOT",1.308993851,-1.862111385,"NOT","NOT",1.93618133]
["K01923","purC; phosphoribosylaminoimidazole-succinocarboxamide synthase [EC:6.3.2.6]","NOT","NOT",5.862920524,"NOT",5.862920524,"NOT",5.862920524]
["K01933","purM; phosphoribosylformylglycinamidine cyclo-ligase [EC:6.3.3.1]","NOT",-5.764432145,"NOT",-5.803423907,"NOT",-5.764432145,6.752121622]
["K01937","pyrG, CTPS; CTP synthase [EC:6.3.4.2]","NOT","NOT","NOT","NOT","NOT","NOT","NOT"]
["K01940","argG, ASS1; argininosuccinate synthase [EC:6.3.4.5]",-7.216139737,-1.626915969,-1.419850795,5.589223768,5.796288942,-7.216139737,5.796288942]
["K01952","purL, PFAS; phosphoribosylformylglycinamidine synthase [EC:6.3.5.3]","NOT",-7.285333145,"NOT",-7.505723219,"NOT",-7.285333145,8.074709873]
["K01958","PC, pyc; pyruvate carboxylase [EC:6.4.1.1]",-1.154907642,"NOT","NOT","NOT",1.139011089,-1.262895854,1.246999301]
["K01990","ABC-2.A; ABC-2 type transport system ATP-binding protein","NOT",-1.402308218,"NOT","NOT","NOT",-1.292336249,1.307322094]
["K01992","ABC-2.P; ABC-2 type transport system permease protein",-1.561881686,-1.94524205,-2.169013138,"NOT","NOT",-1.021127679,-1.14788546]
["K01995","livG; branched-chain amino acid transport system ATP-binding protein",6.010181176,"NOT",6.734616053,-6.010181176,"NOT","NOT",6.734616053]
["K01996","livF; branched-chain amino acid transport system ATP-binding protein","NOT",6.930814867,8.179643987,6.930814867,8.179643987,5.773896474,2.405747513]
["K01997","livH; branched-chain amino acid transport system permease protein","NOT","NOT",5.619530409,"NOT",5.619530409,"NOT",5.619530409]
["K01998","livM; branched-chain amino acid transport system permease protein","NOT","NOT",6.153270814,"NOT",6.153270814,"NOT",6.153270814]
["K01999","livK; branched-chain amino acid transport system substrate-binding protein","NOT",-7.651260061,1.970416939,-8.010015672,1.611661329,-7.651260061,9.621677001]
["K02003","ABC.CD.A; putative ABC transport system ATP-binding protein",1.074207295,-2.292966295,3.452295716,-3.36717359,2.378088421,-6.764912773,10.21720849]
["K02004","ABC.CD.P; putative ABC transport system permease protein","NOT","NOT",3.232680495,-5.837104021,1.818913371,"NOT",7.656017392]
["K02010","afuC, fbpC; iron(III) transport system ATP-binding protein [EC:3.6.3.30]",1.034480913,-5.053471379,2.895173794,-6.087952291,1.860692882,-5.053471379,7.948645173]
["K02011","afuB, fbpB; iron(III) transport system permease protein","NOT",-6.916828838,"NOT",-6.786671089,"NOT",-6.916828838,7.616808446]
["K02012","afuA, fbpA; iron(III) transport system substrate-binding protein",1.849501619,-7.107272407,3.549160465,-8.956774026,1.699658846,-7.107272407,10.65643287]
["K02013","ABC.FEV.A; iron complex transport system ATP-binding protein [EC:3.6.3.34]","NOT","NOT",6.467195641,"NOT",3.355557805,"NOT","NOT"]
["K02015","ABC.FEV.P; iron complex transport system permease protein","NOT","NOT","NOT",-4.49705342,"NOT","NOT","NOT"]
["K02016","ABC.FEV.S; iron complex transport system substrate-binding protein",5.02648666,"NOT",6.055929845,-5.02648666,"NOT","NOT",6.055929845]
["K02025","ABC.MS.P; multiple sugar transport system permease protein","NOT","NOT",4.356056574,"NOT",4.356056574,"NOT","NOT"]
["K02027","ABC.MS.S; multiple sugar transport system substrate-binding protein","NOT","NOT",4.839528261,"NOT",4.839528261,"NOT","NOT"]
["K02031","ABC.PE.A; peptide/nickel transport system ATP-binding protein",2.558448776,"NOT",3.433351529,-7.391055156,"NOT","NOT",8.26595791]
["K02032","ABC.PE.A1; peptide/nickel transport system ATP-binding protein","NOT","NOT",5.982427827,"NOT",5.982427827,"NOT",5.982427827]
["K02033","ABC.PE.P; peptide/nickel transport system permease protein","NOT",-6.687662915,1.316365265,-6.336377227,1.667650952,-6.687662915,8.004028179]
["K02034","ABC.PE.P1; peptide/nickel transport system permease protein",-5.396258059,-5.396258059,"NOT","NOT",5.814787868,-5.396258059,5.814787868]
["K02035","ABC.PE.S; peptide/nickel transport system substrate-binding protein",1.906272167,-6.424676415,3.759257435,-8.330948582,1.852985267,-6.424676415,10.18393385]
["K02037","pstC; phosphate transport system permease protein",-2.81630738,-8.138051738,"NOT",-5.321744357,3.298997958,-8.138051738,8.620742316]
["K02040","pstS; phosphate transport system substrate-binding protein","NOT",-5.953810838,1.291522852,-5.061524243,2.183809447,-10.1750892,11.46661205]
["K02044","phnD; phosphonate transport system substrate-binding protein",-1.065771625,"NOT","NOT","NOT","NOT","NOT","NOT"]
["K02049","ABC.SN.A; NitT/TauT family transport system ATP-binding protein","NOT",-7.492326861,1.95534497,-7.721155571,1.72651626,-7.492326861,9.447671831]
["K02056","ABC.SS.A; simple sugar transport system ATP-binding protein [EC:3.6.3.17]",3.312307239,"NOT",4.5991327,-5.750915609,1.28682546,"NOT",7.037741069]
["K02057","ABC.SS.P; simple sugar transport system permease protein","NOT","NOT",6.696488564,"NOT",6.696488564,"NOT",6.696488564]
["K02058","ABC.SS.S; simple sugar transport system substrate-binding protein","NOT",-7.032312217,2.276394843,-7.348805704,1.959901356,-7.032312217,9.30870706]
["K02067","mlaD, linM; phospholipid/cholesterol/gamma-HCH transport system substrate-binding protein",-5.423142127,-5.423142127,2.3840493,"NOT",7.807191427,-5.423142127,7.807191427]
["K02145","ATPeV1A, ATP6A; V-type H+-transporting ATPase subunit A [EC:7.1.2.2]","NOT",-1.075352853,"NOT","NOT","NOT","NOT","NOT"]
["K02146","ATPeV0D, ATP6D; V-type H+-transporting ATPase subunit d","NOT",7.275278576,"NOT",12.6000585,"NOT",7.22933909,-12.55411902]
["K02147","ATPeV1B, ATP6B; V-type H+-transporting ATPase subunit B","NOT",4.125258437,"NOT",4.683696662,"NOT",3.756765986,-3.831490854]
["K02148","ATPeV1C, ATP6C; V-type H+-transporting ATPase subunit C","NOT","NOT","NOT","NOT","NOT","NOT",-1.50075482]
["K02149","ATPeV1D, ATP6M; V-type H+-transporting ATPase subunit D","NOT","NOT","NOT",1.307256617,"NOT","NOT","NOT"]
["K02150","ATPeV1E, ATP6E; V-type H+-transporting ATPase subunit E","NOT","NOT",-1.02281796,"NOT","NOT","NOT",-1.466567508]
["K02155","ATPeV0C, ATP6L; V-type H+-transporting ATPase 16kDa proteolipid subunit","NOT",1.079391645,"NOT",1.828129538,"NOT",1.146599094,-1.833607457]
["K02261","COX2; cytochrome c oxidase subunit 2","NOT",15.76330413,"NOT",15.76330413,"NOT","NOT","NOT"]
["K02266","COX6A; cytochrome c oxidase subunit 6a","NOT","NOT","NOT","NOT",-1.40753119,"NOT",-1.297086558]
["K02267","COX6B; cytochrome c oxidase subunit 6b","NOT",1.153090105,"NOT",1.699364329,"NOT","NOT","NOT"]
["K02291","crtB; 15-cis-phytoene synthase [EC:2.5.1.32]","NOT","NOT","NOT",-5.336564268,-5.336564268,"NOT","NOT"]
["K02324","POLE; DNA polymerase epsilon subunit 1 [EC:2.7.7.7]",1.118198531,1.426850505,"NOT","NOT","NOT",1.950078232,-1.389215396]
["K02325","POLE2; DNA polymerase epsilon subunit 2 [EC:2.7.7.7]","NOT",1.230117608,"NOT","NOT",-1.101811485,1.99822002,-2.860367258]
["K02501","hisH; glutamine amidotransferase [EC:2.4.2.-]","NOT",-7.252680916,"NOT",-6.933701195,1.249468154,-7.252680916,8.183169348]
["K02517","lpxL, htrB; Kdo2-lipid IVA lauroyltransferase [EC:2.3.1.241]",-1.083936438,-5.992584099,1.208774575,-4.908647661,2.292711013,-5.992584099,7.201358674]
["K02527","kdtA, waaA; 3-deoxy-D-manno-octulosonic-acid transferase [EC:2.4.99.12 2.4.99.13 2.4.99.14 2.4.99.15]","NOT",-4.952802476,2.955599139,-5.893895214,2.014506401,-4.952802476,7.908401615]
["K02599","NOTCH1; Notch 1",-5.71751809,2.871032831,-5.71751809,8.588550921,"NOT",1.826903541,-7.544421631]
["K02841","waaC, rfaC; heptosyltransferase I [EC:2.4.-.-]","NOT",-6.538149705,1.075046549,-6.186249319,1.426946936,-6.538149705,7.613196254]
["K03006","RPB1, POLR2A; DNA-directed RNA polymerase II subunit RPB1 [EC:2.7.7.6]","NOT",1.908915224,"NOT",2.254926226,"NOT",1.371873523,-1.282339355]
["K03008","RPB11, POLR2J; DNA-directed RNA polymerase II subunit RPB11","NOT","NOT","NOT","NOT","NOT",-9.369172055,8.932627561]
["K03010","RPB2, POLR2B; DNA-directed RNA polymerase II subunit RPB2 [EC:2.7.7.6]","NOT",10.45772366,"NOT",10.45772366,"NOT",10.16120732,-10.16120732]
["K03011","RPB3, POLR2C; DNA-directed RNA polymerase II subunit RPB3","NOT",2.467248899,"NOT",1.627284155,"NOT",1.503087257,-1.019365086]
["K03015","RPB7, POLR2G; DNA-directed RNA polymerase II subunit RPB7","NOT",9.882922331,"NOT",9.882922331,"NOT",9.553253231,-9.553253231]
["K03094","SKP1, CBF3D; S-phase kinase-associated protein 1","NOT",12.09580952,"NOT",12.09580952,"NOT",11.98269327,-11.98269327]
["K03271","gmhA, lpcA; D-sedoheptulose 7-phosphate isomerase [EC:5.3.1.28]",1.384520478,-7.744379545,2.383720104,-9.128900023,"NOT",-1.472928546,3.856648651]
["K03273","gmhB; D-glycero-D-manno-heptose 1,7-bisphosphate phosphatase [EC:3.1.3.82 3.1.3.83]","NOT",-5.50138843,2.183692619,-4.549156868,3.135924181,-5.50138843,7.685081049]
["K03283","HSPA1s; heat shock 70kDa protein 1/2/6/8","NOT","NOT","NOT",1.574999101,"NOT",1.260331077,-1.127606017]
["K03347","CUL1, CDC53; cullin 1",1.093059853,"NOT","NOT","NOT","NOT","NOT","NOT"]
["K03362","FBXW1_11, BTRC, beta-TRCP; F-box and WD-40 domain protein 1/11","NOT","NOT","NOT","NOT",1.144218126,"NOT","NOT"]
["K03585","acrA, mexA, adeI, smeD, mtrC, cmeA; membrane fusion protein, multidrug efflux system","NOT",-6.563313272,"NOT",-5.928207908,1.188904665,-6.563313272,7.117112573]
["K03673","dsbA; thiol:disulfide interchange protein DsbA",1.321775255,-8.0291981,3.085218534,-9.350973355,1.763443279,-8.0291981,11.11441663]
["K03732","rhlB; ATP-dependent RNA helicase RhlB [EC:3.6.4.13]","NOT","NOT",5.360838518,"NOT",5.360838518,6.271450998,"NOT"]
["K03781","katE, CAT, catB, srpA; catalase [EC:1.11.1.6]","NOT",1.602598722,"NOT",1.610313126,"NOT",1.355099182,-1.057985678]
["K03868","RBX1, ROC1; RING-box protein 1 [EC:2.3.2.32]","NOT",1.225286933,"NOT",1.326371106,"NOT","NOT","NOT"]
["K03872","ELOC, TCEB1; elongin-C","NOT",10.53117882,"NOT",10.53117882,"NOT",10.23457997,-10.23457997]
["K04127","cefD; isopenicillin-N epimerase [EC:5.1.1.17]",4.670960801,"NOT",7.040638643,-4.670960801,2.369677842,"NOT",7.040638643]
["K04368","MAP2K1, MEK1; mitogen-activated protein kinase kinase 1 [EC:2.7.12.2]","NOT",3.043799008,"NOT","NOT","NOT","NOT","NOT"]
["K04371","ERK, MAPK1_3; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]","NOT",1.60882462,"NOT",1.126807671,"NOT",1.466768491,"NOT"]
["K04427","MAP3K7, TAK1; mitogen-activated protein kinase kinase kinase 7 [EC:2.7.11.25]","NOT",-6.503343089,"NOT",-7.280958588,"NOT","NOT","NOT"]
["K04505","PSEN1, PS1; presenilin 1 [EC:3.4.23.-]","NOT","NOT","NOT","NOT",-1.114154723,"NOT","NOT"]
["K04730","IRAK1; interleukin-1 receptor-associated kinase 1 [EC:2.7.11.1]",6.226241401,5.32912254,"NOT","NOT",-6.226241401,"NOT","NOT"]
["K04771","degP, htrA; serine protease Do [EC:3.4.21.107]","NOT","NOT",2.966483778,"NOT",3.12748256,-8.04361083,11.01009461]
["K05546","GANAB; mannosyl-oligosaccharide alpha-1,3-glucosidase [EC:3.2.1.207]","NOT",-1.393913709,"NOT",-1.16666294,"NOT","NOT","NOT"]
["K05685","macB; macrolide transport system ATP-binding/permease protein [EC:3.6.3.-]",-4.795724608,-4.795724608,2.331314892,"NOT",7.1270395,"NOT",7.1270395]
["K05772","tupA, vupA; tungstate transport system substrate-binding protein","NOT",-6.418187695,"NOT",-5.905213912,"NOT",-6.418187695,5.825904975]
["K05917","CYP51; sterol 14alpha-demethylase [EC:1.14.14.154]",-1.069345125,-1.268095767,"NOT","NOT","NOT","NOT","NOT"]
["K06041","kdsD, kpsF; arabinose-5-phosphate isomerase [EC:5.3.1.13]","NOT",-6.170199968,1.797991879,-6.616142966,1.352048882,-6.170199968,7.968191847]
["K06053","RBPSUH, RBPJK; recombining binding protein suppressor of hairless","NOT","NOT","NOT","NOT","NOT","NOT",1.361830065]
["K06861","lptB; lipopolysaccharide export system ATP-binding protein [EC:3.6.3.-]",1.381764911,-5.740295747,2.312032984,-7.122060658,"NOT",-5.740295747,8.052328731]
["K06998","phzF; trans-2,3-dihydro-3-hydroxyanthranilate isomerase [EC:5.3.3.17]","NOT","NOT","NOT",1.051388927,"NOT",-6.938829193,6.969088825]
["K07151","STT3; dolichyl-diphosphooligosaccharide---protein glycosyltransferase [EC:2.4.99.18]","NOT","NOT","NOT","NOT","NOT","NOT",-1.275170711]
["K07512","MECR, NRBF1; mitochondrial trans-2-enoyl-CoA reductase [EC:1.3.1.38]",-1.211793988,-1.343169445,"NOT","NOT","NOT",-8.09091147,7.561877915]
["K07537","dch; cyclohexa-1,5-dienecarbonyl-CoA hydratase [EC:4.2.1.100]",1.866447332,"NOT","NOT","NOT",-10.25495633,"NOT",-10.13787835]
["K07638","envZ; two-component system, OmpR family, osmolarity sensor histidine kinase EnvZ [EC:2.7.13.3]",-5.311448505,-5.311448505,1.213036183,"NOT",6.524484688,-5.311448505,6.524484688]
["K07640","cpxA; two-component system, OmpR family, sensor histidine kinase CpxA [EC:2.7.13.3]","NOT","NOT","NOT","NOT",6.856088942,"NOT","NOT"]
["K07642","baeS, smeS; two-component system, OmpR family, sensor histidine kinase BaeS [EC:2.7.13.3]",2.855136438,"NOT",3.057359514,-6.412932057,"NOT","NOT",6.615155133]
["K07644","cusS, copS, silS; two-component system, OmpR family, heavy metal sensor histidine kinase CusS [EC:2.7.13.3]",-1.304339496,-7.973295295,1.261615077,-6.6689558,2.565954573,-7.973295295,9.234910373]
["K07659","ompR; two-component system, OmpR family, phosphate regulon response regulator OmpR","NOT",-6.849247261,2.099889684,-7.30543997,1.643696975,-6.849247261,8.949136944]
["K07748","E1.1.1.170, NSDHL, ERG26; sterol-4alpha-carboxylate 3-dehydrogenase (decarboxylating) [EC:1.1.1.170]","NOT",1.295201654,1.397699386,1.083570096,1.186067828,"NOT",1.133633212]
["K07799","mdtA; membrane fusion protein, multidrug efflux system",1.329597258,-6.723596823,3.035567895,-8.053194082,1.705970637,-6.723596823,9.759164718]
["K08151","tetA; MFS transporter, DHA1 family, tetracycline resistance protein","NOT",-1.077273409,"NOT","NOT","NOT","NOT","NOT"]
["K08218","ampG; MFS transporter, PAT family, beta-lactamase induction signal transducer AmpG","NOT",-5.008238386,1.414372634,-5.608608302,"NOT",-5.008238386,6.42261102]
["K08300","rne; ribonuclease E [EC:3.1.26.12]","NOT",-5.766112955,1.470514033,-5.974235542,1.262391446,-5.766112955,7.236626988]
["K08310","nudB, ntpA; dihydroneopterin triphosphate diphosphatase [EC:3.6.1.67]",6.482505647,"NOT",7.57875627,-6.482505647,1.096250623,"NOT",7.57875627]
["K08764","SCP2, SCPX; sterol carrier protein 2 [EC:2.3.1.176]","NOT","NOT",2.273134343,"NOT",2.63971273,"NOT",1.925760032]
["K09481","SEC61B, SBH2; protein transport protein SEC61 subunit beta","NOT",1.39415218,"NOT","NOT",-1.257419681,1.491065115,-2.09829454]
["K09688","ABC-2.CPSE.P; capsular polysaccharide transport system permease protein",-1.615727715,-7.591992177,"NOT",-5.976264462,1.241780473,-7.591992177,7.218044935]
["K09689","ABC-2.CPSE.A; capsular polysaccharide transport system ATP-binding protein [EC:3.6.3.38]","NOT",-6.518012369,1.162303077,-6.932550453,"NOT",-6.518012369,7.680315446]
["K09696","natB; sodium transport system permease protein",-1.637228714,-5.653787093,1.752237382,-4.016558379,3.389466097,-5.653787093,7.406024475]
["K09697","natA; sodium transport system ATP-binding protein [EC:7.2.2.3]","NOT","NOT",6.746241106,"NOT",6.746241106,"NOT",6.746241106]
["K09709","meh; 3-methylfumaryl-CoA hydratase [EC:4.2.1.153]","NOT","NOT",5.386463611,"NOT",5.386463611,"NOT",5.386463611]
["K09828","DHCR24, DWF1; Delta24-sterol reductase [EC:1.3.1.72 1.3.1.-]",-1.483850719,"NOT",-1.338010001,"NOT","NOT","NOT",-1.816250808]
["K09831","ERG5, CYP61A; sterol 22-desaturase [EC:1.14.19.41]","NOT",-3.603490588,"NOT",-4.053398232,"NOT",-8.234733011,9.050766009]
["K09835","crtISO, crtH; prolycopene isomerase [EC:5.2.1.13]","NOT",8.405711337,"NOT",8.405711337,"NOT",7.766715587,-7.766715587]
["K10001","gltI, aatJ; glutamate/aspartate transport system substrate-binding protein",5.449053014,"NOT",7.211526256,-5.449053014,1.762473242,"NOT",7.211526256]
["K10022","aotJ; arginine/ornithine transport system substrate-binding protein","NOT","NOT",2.225388123,-5.385021792,"NOT","NOT",7.026088861]
["K10023","aotM; arginine/ornithine transport system permease protein",4.488341887,"NOT",6.818073466,-4.488341887,2.329731579,"NOT",6.818073466]
["K10036","glnH; glutamine transport system substrate-binding protein","NOT","NOT",-1.698222994,"NOT",-2.642503119,2.142297208,-3.840520202]
["K10107","ABC-2.CPSE.P1; capsular polysaccharide transport system permease protein","NOT",-6.257180869,1.554827966,-7.050854513,"NOT",-6.257180869,7.812008835]
["K10108","malE; maltose/maltodextrin transport system substrate-binding protein","NOT",-7.418472524,1.33278631,-7.971549494,"NOT",-7.418472524,8.751258834]
["K10109","malF; maltose/maltodextrin transport system permease protein","NOT",-6.125260499,2.339783718,-6.42909223,2.035951986,-6.125260499,8.465044216]
["K10110","malG; maltose/maltodextrin transport system permease protein",1.128958233,-5.818923259,1.71262004,-6.947881493,"NOT",-5.818923259,7.531543299]
["K10111","malK, mtlK, thuK; multiple sugar transport system ATP-binding protein [EC:3.6.3.-]","NOT",-7.607754437,1.642192821,-6.905689069,2.344258188,-7.607754437,9.249947257]
["K10216","dmpD, xylF; 2-hydroxymuconate-semialdehyde hydrolase [EC:3.7.1.9]",-4.619931896,-4.619931896,-4.619931896,"NOT","NOT","NOT","NOT"]
["K10217","dmpC, xylG, praB; aminomuconate-semialdehyde/2-hydroxymuconate-6-semialdehyde dehydrogenase [EC:1.2.1.32 1.2.1.85]",-1.721570801,-1.477596163,"NOT","NOT",1.716450872,-7.171195406,7.166075478]
["K10245","ELO2; fatty acid elongase 2 [EC:2.3.1.199]",-1.006391695,-1.165437077,-1.279759281,"NOT","NOT",-9.8502838,8.570524519]
["K10246","ELO3; fatty acid elongase 3 [EC:2.3.1.199]",7.273638048,"NOT",8.028540693,-7.273638048,"NOT",8.373575523,"NOT"]
["K10249","ELOVL4; elongation of very long chain fatty acids protein 4 [EC:2.3.1.199]","NOT",-2.22194195,-1.229242431,-2.227665963,-1.234966443,-1.320303095,"NOT"]
["K10251","HSD17B12, KAR, IFA38; 17beta-estradiol 17-dehydrogenase / very-long-chain 3-oxoacyl-CoA reductase [EC:1.1.1.62 1.1.1.330]","NOT","NOT","NOT",-1.329317728,"NOT","NOT","NOT"]
["K10258","TER, TSC13, CER10; very-long-chain enoyl-CoA reductase [EC:1.3.1.93]","NOT","NOT",-1.221603525,"NOT",-1.215799041,"NOT",-1.953977558]
["K10599","PRPF19, PRP19; pre-mRNA-processing factor 19 [EC:2.3.2.27]","NOT","NOT","NOT",1.22421993,"NOT","NOT","NOT"]
["K10896","FANCM; fanconi anemia group M protein","NOT","NOT",1.051949187,"NOT","NOT",1.788687077,"NOT"]
["K10956","SEC61A; protein transport protein SEC61 subunit alpha","NOT",11.793398,"NOT",11.793398,"NOT",12.44393561,-12.44393561]
["K11073","potF; putrescine transport system substrate-binding protein",6.463777781,"NOT",9.112936034,-6.463777781,2.649158252,"NOT",9.112936034]
["K11074","potI; putrescine transport system permease protein",4.800304633,"NOT",7.045372376,-4.800304633,2.245067743,"NOT",7.045372376]
["K11075","potH; putrescine transport system permease protein","NOT","NOT","NOT","NOT",6.796480191,"NOT","NOT"]
["K11076","potG; putrescine transport system ATP-binding protein",6.338341288,"NOT",8.847395593,-6.338341288,2.509054305,"NOT",8.847395593]
["K11086","SNRPB, SMB; small nuclear ribonucleoprotein B and B'","NOT","NOT","NOT","NOT",-1.032003432,"NOT","NOT"]
["K11087","SNRPD1, SMD1; small nuclear ribonucleoprotein D1",-5.256737817,3.421410804,"NOT",8.678148621,"NOT",3.524933319,-8.781671136]
["K11088","SNRPD3, SMD3; small nuclear ribonucleoprotein D3","NOT","NOT","NOT","NOT",-1.204173596,"NOT","NOT"]
["K11096","SNRPD2, SMD2; small nuclear ribonucleoprotein D2","NOT",10.44655288,"NOT",10.44655288,"NOT",10.36999527,-10.36999527]
["K11098","SNRPF, SMF; small nuclear ribonucleoprotein F","NOT",9.813993377,"NOT",9.813993377,"NOT","NOT","NOT"]
["K11175","purN; phosphoribosylglycinamide formyltransferase 1 [EC:2.1.2.2]","NOT","NOT",7.129611014,"NOT",7.129611014,"NOT",7.129611014]
["K11204","GCLC; glutamate--cysteine ligase catalytic subunit [EC:6.3.2.2]",1.263255568,"NOT",1.183405695,-1.478168936,"NOT","NOT",1.28601847]
["K11205","GCLM; glutamate--cysteine ligase regulatory subunit",1.233236841,1.052001386,"NOT","NOT","NOT","NOT","NOT"]
["K11517","HAO; (S)-2-hydroxy-acid oxidase [EC:1.1.3.15]","NOT","NOT","NOT","NOT",1.067196309,"NOT","NOT"]
["K11954","K11954, natB; neutral amino acid transport system substrate-binding protein",-1.622231072,-6.115525547,"NOT",-4.493294474,"NOT",-6.115525547,5.501429087]
["K11959","urtA; urea transport system substrate-binding protein",-7.525097967,"NOT","NOT",6.639299758,7.549764076,-7.525097967,7.549764076]
["K12183","TSG101, STP22, VPS23; ESCRT-I complex subunit TSG101","NOT","NOT","NOT","NOT","NOT",7.31157811,-7.31157811]
["K12340","tolC; outer membrane protein",1.519722528,-5.865480654,3.131973076,-7.385203182,1.612250548,-5.865480654,8.99745373]
["K12405","HSD17B4; 3-hydroxyacyl-CoA dehydrogenase / 3a,7a,12a-trihydroxy-5b-cholest-24-enoyl-CoA hydratase / enoyl-CoA hydratase 2 [EC:1.1.1.35 4.2.1.107 4.2.1.119]","NOT","NOT",1.066302449,"NOT",1.178092487,"NOT","NOT"]
["K12602","WDR61, REC14, SKI8; WD repeat-containing protein 61","NOT","NOT","NOT","NOT","NOT",8.95550025,-8.95550025]
["K12621","LSM2; U6 snRNA-associated Sm-like protein LSm2","NOT",1.770412005,"NOT",1.05501378,"NOT",1.336457148,-1.175065367]
["K12623","LSM4; U6 snRNA-associated Sm-like protein LSm4","NOT",5.486303289,"NOT",5.486303289,"NOT","NOT","NOT"]
["K12626","LSM7; U6 snRNA-associated Sm-like protein LSm7","NOT","NOT","NOT","NOT","NOT","NOT",-1.265058802]
["K12666","OST1, RPN1; oligosaccharyltransferase complex subunit alpha (ribophorin I)","NOT","NOT",-2.228535779,"NOT",-2.298322124,"NOT",-1.711550391]
["K12667","SWP1, RPN2; oligosaccharyltransferase complex subunit delta (ribophorin II)","NOT","NOT",-1.557973898,"NOT",-2.073805273,"NOT",-1.772275496]
["K12668","OST2, DAD1; oligosaccharyltransferase complex subunit epsilon","NOT","NOT",-1.515360416,-1.219143529,-2.156956311,"NOT",-1.136544034]
["K12669","OST3, OST6; oligosaccharyltransferase complex subunit gamma","NOT","NOT",-1.546793447,"NOT",-1.951617169,"NOT",-1.310857445]
["K12670","WBP1; oligosaccharyltransferase complex subunit beta","NOT","NOT",-1.493864777,"NOT",-1.257767779,"NOT",-1.478446307]
["K12812","UAP56, BAT1, SUB2; ATP-dependent RNA helicase UAP56/SUB2 [EC:3.6.4.13]",10.38285871,13.40158643,10.59825615,"NOT","NOT",13.33524402,"NOT"]
["K12860","CDC5L, CDC5, CEF1; pre-mRNA-splicing factor CDC5/CEF1","NOT",-1.102121843,"NOT",-1.305587491,"NOT","NOT","NOT"]
["K12861","BCAS2; pre-mRNA-splicing factor SPF27","NOT",1.712006366,"NOT",1.11687059,"NOT",1.228585436,-1.608353636]
["K12862","PLRG1, PRL1, PRP46; pleiotropic regulator 1","NOT","NOT","NOT","NOT","NOT","NOT",-1.37501981]
["K12864","CTNNBL1; beta-catenin-like protein 1","NOT",1.473071912,"NOT","NOT","NOT",1.344476047,-1.329323691]
["K12866","WBP11, NPWBP; WW domain-binding protein 11",6.091273231,7.087184502,"NOT","NOT",-6.091273231,7.877296921,-7.877296921]
["K12880","THOC3; THO complex subunit 3","NOT",1.424437303,"NOT","NOT","NOT","NOT","NOT"]
["K12881","THOC4, ALY; THO complex subunit 4",-1.106065955,-1.776123862,"NOT","NOT",1.872199221,-1.14798884,1.914122107]
["K13175","THOC6; THO complex subunit 6",4.501736724,"NOT","NOT",-4.501736724,-4.501736724,"NOT","NOT"]
["K13250","SSR2; translocon-associated protein subunit beta","NOT","NOT",-2.321474097,"NOT",-2.205816045,"NOT",-1.90813045]
["K13251","SSR3; translocon-associated protein subunit gamma","NOT","NOT",-1.574460194,"NOT",-2.136899941,"NOT",-2.168703087]
["K13800","CMPK1, UMPK; UMP-CMP kinase [EC:2.7.4.14]","NOT","NOT",-1.028917612,"NOT","NOT","NOT",-1.188289192]
["K13998","DHFR-TS; dihydrofolate reductase / thymidylate synthase [EC:1.5.1.3 2.1.1.45]","NOT","NOT","NOT",1.200517198,"NOT",-8.164624704,8.45301462]
["K14266","prnA, rebH, ktzQ; tryptophan 7-halogenase [EC:1.14.19.9]",1.29133216,-5.336786672,2.782373951,-6.628118832,1.491041791,-5.336786672,8.119160623]
["K14267","dapC; N-succinyldiaminopimelate aminotransferase [EC:2.6.1.17]","NOT","NOT","NOT",-6.583584681,-6.583584681,3.727913244,-9.056711029]
["K14367","eryBV; erythronolide mycarosyltransferase [EC:2.4.1.328]",7.680154848,"NOT","NOT",-7.680154848,-7.680154848,"NOT","NOT"]
["K14584","nahD; 2-hydroxychromene-2-carboxylate isomerase [EC:5.99.1.4]",5.185936142,"NOT","NOT",-5.185936142,-5.185936142,"NOT","NOT"]
["K16246","dmpP, poxF; phenol hydroxylase P5 protein",7.438888992,8.296688671,7.923822409,"NOT","NOT",7.814623438,"NOT"]
["K17222","soxA; sulfur-oxidizing protein SoxA",4.910212447,"NOT",7.63333924,-4.910212447,2.723126793,"NOT",7.63333924]
["K17224","soxB; S-sulfosulfanyl-L-cysteine sulfohydrolase [EC:3.1.6.20]",4.983089093,"NOT",8.121508863,-4.983089093,3.13841977,"NOT",8.121508863]
["K17315","gtsA, glcE; glucose/mannose transport system substrate-binding protein",-1.737517242,-6.690798435,"NOT",-4.953281193,2.602771528,-6.690798435,7.556052721]
["K17325","K17325, glpT; glycerol transport system ATP-binding protein",6.42949701,"NOT",8.560672211,-6.42949701,2.131175201,"NOT",8.560672211]
["K17475","FTMC, CYP5076C; tryprostatin B 6-hydroxylase [EC:1.14.14.118]",6.923613828,7.736069231,9.653721161,"NOT",2.730107332,7.203002646,2.450718515]
["K17836","penP; beta-lactamase class A [EC:3.5.2.6]",4.381164084,"NOT",5.520288904,-4.381164084,"NOT","NOT",5.520288904]
["K17865","croR; 3-hydroxybutyryl-CoA dehydratase [EC:4.2.1.55]","NOT",8.998523797,"NOT",8.998523797,"NOT",8.308414965,-8.308414965]
["K18107","GAAD; L-glyceraldehyde reductase [EC:1.1.1.372]",-8.976581456,-2.000924697,-8.976581456,6.975656759,"NOT","NOT",-9.263051028]
["K18138","acrB, mexB, adeJ, smeE, mtrD, cmeB; multidrug efflux pump","NOT",-4.994543158,1.22024879,-5.599512472,"NOT",-4.994543158,6.214791948]
["K18302","mexJ; membrane fusion protein, multidrug efflux system","NOT",-4.065748557,6.381610905,-5.253008583,5.194350879,"NOT",10.44735946]
["K18303","mexK; multidrug efflux pump",1.072482718,-6.462762666,3.441743405,-7.535245384,2.369260688,-6.462762666,9.904506072]
["K18889","mdlA, smdA; ATP-binding cassette, subfamily B, multidrug efflux pump","NOT",-5.134260316,"NOT",-4.870479863,"NOT",-5.134260316,4.977541951]
["K18900","bpeT; LysR family transcriptional regulator, regulator for bpeEF and oprC",6.110346815,"NOT",8.864290391,-6.110346815,2.753943576,"NOT",8.864290391]
["K18906","mgrA; MarR family transcriptional regulator, multiple gene regulator MgrA","NOT","NOT",6.769956799,"NOT",6.769956799,"NOT",6.769956799]
["K18939","lmrA, yxaF; TetR/AcrR family transcriptional regulator, lmrAB and yxaGH operons repressor",5.604609428,"NOT",6.853200859,-5.604609428,1.248591431,"NOT",6.853200859]