File Name : supplementary figure 1.tif Caption : supplementary figure 1 effects of amts alone on the protein levels of cyp2e1, p62, and lc3. mice were treated with different doses of amts (25-100 mg/kg body weight) or vehicle for 7 days, and then sacrificed. the liver were harvested and total protein extracts were prepared using ripa buffer. (a) representative western blot bands of cyp2e1, p62, and lc3; (b) quantitative data analyses of cyp2e1, p62, and lc3. * p<0.05, compared with the control group mice. File Name : supplementary figure 2.tif Caption : supplementary figure 2 effects of amts alone on the protein levels of nuclear nrf-2 and the mrna levels of nrf-2-targeted genes in mice. mice were randomized into 4 groups, i.e. control group, 25 mg/kg amts group, 50 mg/kg amts group, 100 mg/kg amts group (n=5). the mice were treated with different doses of amts or vehicle for 7 days, and then sacrificed. the liver were harvested and the nuclear fractions were prepared as described in the materials and methods. (a) representative western blot bands of nuclear nrf-2; (b) mrna levels of nrf-2, nqo-1, ho-1, sod, gclm, and gclc. * p<0.05, compared with the control group mice.