# Electronic Supplementary Material (ESI) for Chemical Communications
# This journal is © The Royal Society of Chemistry 2012


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#                                CCDC 
# 
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# 
#  This CIF contains data from an original supplementary publication 
#  deposited with the CCDC, and may include chemical, crystal,   
#  experimental, refinement, atomic coordinates, 
#  anisotropic displacement parameters and molecular geometry data,
#  as required by the journal to which it was submitted. 
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#  fide research purposes only. It may contain copyright material 
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#  except for the purpose of generating routine backup copies 
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data_shelxl
_database_code_depnum_ccdc_archive 'CCDC 902010'
#TrackingRef 'SHELXL.CIF'


_audit_creation_method           SHELXL-97
_chemical_name_systematic        
;
?
;
_chemical_name_common            ?
_chemical_melting_point          ?
_chemical_formula_moiety         ?
_chemical_formula_sum            'C22 H23 N O6'
_chemical_formula_weight         397.41

loop_
_atom_type_symbol
_atom_type_description
_atom_type_scat_dispersion_real
_atom_type_scat_dispersion_imag
_atom_type_scat_source
C C 0.0033 0.0016 'International Tables Vol C Tables 4.2.6.8 and 6.1.1.4'
H H 0.0000 0.0000 'International Tables Vol C Tables 4.2.6.8 and 6.1.1.4'
N N 0.0061 0.0033 'International Tables Vol C Tables 4.2.6.8 and 6.1.1.4'
O O 0.0106 0.0060 'International Tables Vol C Tables 4.2.6.8 and 6.1.1.4'

_symmetry_cell_setting           ?
_symmetry_space_group_name_H-M   ?

loop_
_symmetry_equiv_pos_as_xyz
'x, y, z'
'-x, y, -z+1/2'
'x+1/2, y+1/2, z'
'-x+1/2, y+1/2, -z+1/2'
'-x, -y, -z'
'x, -y, z-1/2'
'-x+1/2, -y+1/2, -z'
'x+1/2, -y+1/2, z-1/2'

_cell_length_a                   27.689(5)
_cell_length_b                   7.9853(16)
_cell_length_c                   18.998(4)
_cell_angle_alpha                90.00
_cell_angle_beta                 93.73(3)
_cell_angle_gamma                90.00
_cell_volume                     4191.7(14)
_cell_formula_units_Z            8
_cell_measurement_temperature    293(2)
_cell_measurement_reflns_used    ?
_cell_measurement_theta_min      ?
_cell_measurement_theta_max      ?

_exptl_crystal_description       ?
_exptl_crystal_colour            ?
_exptl_crystal_size_max          0.63
_exptl_crystal_size_mid          0.12
_exptl_crystal_size_min          0.11
_exptl_crystal_density_meas      ?
_exptl_crystal_density_diffrn    1.259
_exptl_crystal_density_method    'not measured'
_exptl_crystal_F_000             1680
_exptl_absorpt_coefficient_mu    0.092
_exptl_absorpt_correction_type   ?
_exptl_absorpt_correction_T_min  0.9447
_exptl_absorpt_correction_T_max  0.9898
_exptl_absorpt_process_details   ?

_exptl_special_details           
;
?
;

_diffrn_ambient_temperature      293(2)
_diffrn_radiation_wavelength     0.71073
_diffrn_radiation_type           MoK\a
_diffrn_radiation_source         'fine-focus sealed tube'
_diffrn_radiation_monochromator  graphite
_diffrn_measurement_device_type  ?
_diffrn_measurement_method       ?
_diffrn_detector_area_resol_mean ?
_diffrn_standards_number         ?
_diffrn_standards_interval_count ?
_diffrn_standards_interval_time  ?
_diffrn_standards_decay_%        ?
_diffrn_reflns_number            13868
_diffrn_reflns_av_R_equivalents  0.2252
_diffrn_reflns_av_sigmaI/netI    0.1838
_diffrn_reflns_limit_h_min       -31
_diffrn_reflns_limit_h_max       30
_diffrn_reflns_limit_k_min       -9
_diffrn_reflns_limit_k_max       8
_diffrn_reflns_limit_l_min       -21
_diffrn_reflns_limit_l_max       21
_diffrn_reflns_theta_min         3.38
_diffrn_reflns_theta_max         24.00
_reflns_number_total             3288
_reflns_number_gt                883
_reflns_threshold_expression     >2sigma(I)

_computing_data_collection       ?
_computing_cell_refinement       ?
_computing_data_reduction        ?
_computing_structure_solution    'SHELXS-97 (Sheldrick, 1990)'
_computing_structure_refinement  'SHELXL-97 (Sheldrick, 1997)'
_computing_molecular_graphics    ?
_computing_publication_material  ?

_refine_special_details          
;
Refinement of F^2^ against ALL reflections. The weighted R-factor wR and
goodness of fit S are based on F^2^, conventional R-factors R are based
on F, with F set to zero for negative F^2^. The threshold expression of
F^2^ > 2sigma(F^2^) is used only for calculating R-factors(gt) etc. and is
not relevant to the choice of reflections for refinement. R-factors based
on F^2^ are statistically about twice as large as those based on F, and R-
factors based on ALL data will be even larger.
;

_refine_ls_structure_factor_coef Fsqd
_refine_ls_matrix_type           full
_refine_ls_weighting_scheme      calc
_refine_ls_weighting_details     
'calc w=1/[\s^2^(Fo^2^)+(0.1606P)^2^+0.0000P] where P=(Fo^2^+2Fc^2^)/3'
_atom_sites_solution_primary     direct
_atom_sites_solution_secondary   difmap
_atom_sites_solution_hydrogens   geom
_refine_ls_hydrogen_treatment    mixed
_refine_ls_extinction_method     none
_refine_ls_extinction_coef       ?
_refine_ls_number_reflns         3288
_refine_ls_number_parameters     276
_refine_ls_number_restraints     8
_refine_ls_R_factor_all          0.2751
_refine_ls_R_factor_gt           0.0951
_refine_ls_wR_factor_ref         0.3556
_refine_ls_wR_factor_gt          0.2325
_refine_ls_goodness_of_fit_ref   0.903
_refine_ls_restrained_S_all      0.905
_refine_ls_shift/su_max          0.026
_refine_ls_shift/su_mean         0.002

loop_
_atom_site_label
_atom_site_type_symbol
_atom_site_fract_x
_atom_site_fract_y
_atom_site_fract_z
_atom_site_U_iso_or_equiv
_atom_site_adp_type
_atom_site_occupancy
_atom_site_symmetry_multiplicity
_atom_site_calc_flag
_atom_site_refinement_flags
_atom_site_disorder_assembly
_atom_site_disorder_group
C1 C 0.1377(3) 0.3406(10) 0.5164(5) 0.068(3) Uani 1 1 d . . .
C2 C 0.1811(4) 0.3803(11) 0.5533(6) 0.088(3) Uani 1 1 d . . .
H2 H 0.2042 0.2976 0.5632 0.105 Uiso 1 1 calc R . .
C3 C 0.1902(3) 0.5507(11) 0.5764(6) 0.078(3) Uani 1 1 d . A .
C4 C 0.1533(3) 0.6681(11) 0.5585(5) 0.076(3) Uani 1 1 d . . .
H4 H 0.1574 0.7785 0.5733 0.091 Uiso 1 1 calc R . .
C5 C 0.1127(3) 0.6252(11) 0.5208(5) 0.075(3) Uani 1 1 d . . .
H5 H 0.0900 0.7080 0.5086 0.090 Uiso 1 1 calc R . .
C6 C 0.1029(3) 0.4580(10) 0.4987(5) 0.066(3) Uani 1 1 d . . .
C7 C 0.0596(3) 0.4033(10) 0.4620(5) 0.071(3) Uani 1 1 d . . .
H7 H 0.0354 0.4814 0.4505 0.085 Uiso 1 1 calc R . .
C8 C 0.0521(3) 0.2414(11) 0.4432(5) 0.064(3) Uani 1 1 d . . .
C9 C 0.0900(4) 0.1254(11) 0.4600(5) 0.078(3) Uani 1 1 d . . .
C10 C 0.0062(3) 0.1907(11) 0.4094(5) 0.077(3) Uani 1 1 d . . .
H10 H -0.0155 0.2768 0.3979 0.093 Uiso 1 1 calc R . .
C11 C -0.0095(3) 0.0337(13) 0.3923(5) 0.080(3) Uani 1 1 d . . .
H11 H 0.0113 -0.0565 0.4008 0.096 Uiso 1 1 calc R . .
C12 C -0.0566(3) 0.0042(12) 0.3620(5) 0.081(3) Uani 1 1 d . . .
H12 H -0.0760 0.0989 0.3562 0.097 Uiso 1 1 calc R . .
C13 C -0.0784(3) -0.1446(11) 0.3396(5) 0.068(3) Uani 1 1 d . . .
C14 C -0.0545(3) -0.3000(11) 0.3476(5) 0.065(2) Uani 1 1 d . . .
C15 C -0.1086(4) -0.3875(12) 0.2516(6) 0.083(3) Uani 1 1 d . . .
C16 C -0.1269(4) -0.1384(14) 0.3102(6) 0.097(4) Uani 1 1 d . . .
C17 C -0.0818(4) -0.3168(14) 0.1911(6) 0.113(4) Uani 1 1 d . . .
H17A H -0.0618 -0.2252 0.2078 0.169 Uiso 1 1 calc R . .
H17B H -0.1048 -0.2779 0.1546 0.169 Uiso 1 1 calc R . .
H17C H -0.0620 -0.4027 0.1725 0.169 Uiso 1 1 calc R . .
C18 C -0.1352(4) -0.5569(13) 0.2336(7) 0.121(4) Uani 1 1 d . . .
H18A H -0.1125 -0.6367 0.2176 0.182 Uiso 1 1 calc R . .
H18B H -0.1604 -0.5386 0.1972 0.182 Uiso 1 1 calc R . .
H18C H -0.1492 -0.5993 0.2751 0.182 Uiso 1 1 calc R . .
C19 C 0.2769(6) 0.479(2) 0.6074(10) 0.230(12) Uani 1 1 d D A 1
H19A H 0.2748 0.3969 0.5697 0.276 Uiso 1 1 calc R A 1
H19B H 0.3074 0.5390 0.6101 0.276 Uiso 1 1 calc R A 1
C20 C 0.2628(9) 0.430(4) 0.6647(16) 0.042(11) Uani 0.32(4) 1 d PU A 1
H20A H 0.2637 0.5218 0.6975 0.063 Uiso 0.32(4) 1 calc PR A 1
H20B H 0.2836 0.3421 0.6831 0.063 Uiso 0.32(4) 1 calc PR A 1
H20C H 0.2303 0.3890 0.6579 0.063 Uiso 0.32(4) 1 calc PR A 1
C20' C 0.2784(19) 0.359(5) 0.6653(17) 0.32(3) Uani 0.68(4) 1 d PD A 2
H20D H 0.3076 0.3998 0.6891 0.478 Uiso 0.68(4) 1 d PR A 3
H20E H 0.2850 0.2559 0.6415 0.478 Uiso 0.68(4) 1 d PR A 4
H20F H 0.2547 0.3385 0.6991 0.478 Uiso 0.68(4) 1 d PR A 5
C21 C 0.2398(4) 0.7559(11) 0.6437(6) 0.093(4) Uani 1 1 d . A .
H21A H 0.2632 0.7456 0.6837 0.111 Uiso 1 1 calc R . .
H21B H 0.2102 0.8009 0.6608 0.111 Uiso 1 1 calc R . .
C22 C 0.2586(5) 0.8737(16) 0.5921(7) 0.141(5) Uani 1 1 d . . .
H22A H 0.2399 0.8635 0.5480 0.211 Uiso 1 1 calc R . .
H22B H 0.2918 0.8480 0.5854 0.211 Uiso 1 1 calc R . .
H22C H 0.2562 0.9862 0.6094 0.211 Uiso 1 1 calc R . .
N1 N 0.2301(3) 0.5914(11) 0.6137(7) 0.131(5) Uani 1 1 d D . .
O1 O -0.1442(2) -0.2748(9) 0.2749(4) 0.094(2) Uani 1 1 d . . .
O2 O -0.1558(3) -0.0263(12) 0.3139(5) 0.152(4) Uani 1 1 d . . .
O3 O -0.0196(2) -0.3317(8) 0.3869(4) 0.092(2) Uani 1 1 d . . .
O4 O -0.0756(2) -0.4295(7) 0.3096(4) 0.079(2) Uani 1 1 d . . .
O5 O 0.0901(2) -0.0255(8) 0.4438(4) 0.105(3) Uani 1 1 d . . .
O6 O 0.1323(2) 0.1790(6) 0.4965(3) 0.080(2) Uani 1 1 d . . .

loop_
_atom_site_aniso_label
_atom_site_aniso_U_11
_atom_site_aniso_U_22
_atom_site_aniso_U_33
_atom_site_aniso_U_23
_atom_site_aniso_U_13
_atom_site_aniso_U_12
C1 0.074(6) 0.048(5) 0.082(7) -0.007(5) 0.002(5) 0.015(5)
C2 0.086(7) 0.058(6) 0.116(9) -0.007(6) -0.019(7) 0.030(5)
C3 0.068(6) 0.068(6) 0.100(9) -0.011(6) 0.011(6) 0.010(5)
C4 0.076(6) 0.056(5) 0.095(8) -0.009(5) -0.001(6) 0.004(5)
C5 0.070(6) 0.065(6) 0.090(8) 0.005(5) -0.003(6) 0.017(5)
C6 0.077(6) 0.052(5) 0.067(7) -0.006(5) 0.001(5) 0.008(5)
C7 0.081(7) 0.053(5) 0.076(7) 0.005(5) -0.011(6) 0.017(4)
C8 0.064(5) 0.066(6) 0.061(7) 0.002(5) 0.001(5) 0.008(5)
C9 0.100(8) 0.047(5) 0.084(8) 0.006(5) -0.005(6) 0.014(5)
C10 0.078(6) 0.066(6) 0.086(8) -0.014(5) -0.013(6) 0.003(5)
C11 0.055(6) 0.113(8) 0.068(7) -0.012(6) -0.014(5) 0.016(5)
C12 0.073(6) 0.080(6) 0.087(8) -0.008(6) -0.010(6) 0.024(5)
C13 0.042(5) 0.081(6) 0.079(7) -0.021(5) -0.004(5) 0.004(5)
C14 0.053(5) 0.076(6) 0.066(7) 0.007(5) 0.012(5) 0.001(5)
C15 0.088(7) 0.078(7) 0.082(9) -0.002(6) -0.015(7) -0.004(6)
C16 0.082(7) 0.087(7) 0.120(10) -0.036(7) -0.022(7) 0.027(6)
C17 0.133(10) 0.108(9) 0.098(10) 0.010(8) 0.010(8) -0.012(7)
C18 0.134(10) 0.108(9) 0.119(11) -0.007(8) -0.015(8) -0.025(8)
C19 0.24(2) 0.33(3) 0.122(17) -0.063(17) 0.012(16) -0.19(2)
C20 0.045(12) 0.041(12) 0.040(12) 0.002(5) -0.001(5) -0.002(5)
C20' 0.54(8) 0.21(3) 0.18(3) -0.04(3) -0.16(4) 0.16(5)
C21 0.100(8) 0.058(6) 0.117(10) -0.032(6) -0.013(7) -0.007(6)
C22 0.146(12) 0.145(11) 0.131(13) -0.043(10) 0.010(9) -0.068(10)
N1 0.051(5) 0.090(6) 0.246(14) -0.070(7) -0.045(7) 0.020(5)
O1 0.072(4) 0.108(5) 0.101(6) -0.022(5) -0.013(4) 0.019(4)
O2 0.098(6) 0.161(8) 0.189(10) -0.062(7) -0.049(6) 0.057(6)
O3 0.072(4) 0.092(5) 0.107(6) 0.018(4) -0.026(4) 0.002(4)
O4 0.077(4) 0.073(4) 0.087(5) 0.002(4) 0.001(4) -0.001(3)
O5 0.080(4) 0.066(4) 0.163(7) -0.015(5) -0.041(5) 0.021(3)
O6 0.066(4) 0.052(4) 0.118(6) -0.012(4) -0.029(4) 0.013(3)

_geom_special_details            
;
All esds (except the esd in the dihedral angle between two l.s. planes)
are estimated using the full covariance matrix. The cell esds are taken
into account individually in the estimation of esds in distances, angles
and torsion angles; correlations between esds in cell parameters are only
used when they are defined by crystal symmetry. An approximate (isotropic)
treatment of cell esds is used for estimating esds involving l.s. planes.
;

loop_
_geom_bond_atom_site_label_1
_geom_bond_atom_site_label_2
_geom_bond_distance
_geom_bond_site_symmetry_2
_geom_bond_publ_flag
C1 O6 1.350(9) . ?
C1 C6 1.370(10) . ?
C1 C2 1.388(11) . ?
C2 C3 1.447(12) . ?
C2 H2 0.9300 . ?
C3 N1 1.313(11) . ?
C3 C4 1.412(11) . ?
C4 C5 1.339(10) . ?
C4 H4 0.9300 . ?
C5 C6 1.420(11) . ?
C5 H5 0.9300 . ?
C6 C7 1.416(11) . ?
C7 C8 1.354(11) . ?
C7 H7 0.9300 . ?
C8 C9 1.420(11) . ?
C8 C10 1.443(11) . ?
C9 O5 1.244(9) . ?
C9 O6 1.391(10) . ?
C10 C11 1.360(11) . ?
C10 H10 0.9300 . ?
C11 C12 1.411(11) . ?
C11 H11 0.9300 . ?
C12 C13 1.387(11) . ?
C12 H12 0.9300 . ?
C13 C14 1.409(11) . ?
C13 C16 1.420(11) . ?
C14 O3 1.210(9) . ?
C14 O4 1.369(9) . ?
C15 O1 1.425(12) . ?
C15 O4 1.426(10) . ?
C15 C17 1.518(14) . ?
C15 C18 1.568(12) . ?
C16 O2 1.206(10) . ?
C16 O1 1.351(10) . ?
C17 H17A 0.9600 . ?
C17 H17B 0.9600 . ?
C17 H17C 0.9600 . ?
C18 H18A 0.9600 . ?
C18 H18B 0.9600 . ?
C18 H18C 0.9600 . ?
C19 C20 1.24(3) . ?
C19 N1 1.587(17) . ?
C19 H19A 0.9700 . ?
C19 H19B 0.9700 . ?
C20 H20A 0.9600 . ?
C20 H20B 0.9600 . ?
C20 H20C 0.9600 . ?
C20 H20D 1.3180 . ?
C20 H20F 1.0163 . ?
C20' H20D 0.9600 . ?
C20' H20E 0.9600 . ?
C20' H20F 0.9600 . ?
C21 N1 1.451(11) . ?
C21 C22 1.477(15) . ?
C21 H21A 0.9700 . ?
C21 H21B 0.9700 . ?
C22 H22A 0.9600 . ?
C22 H22B 0.9600 . ?
C22 H22C 0.9600 . ?

loop_
_geom_angle_atom_site_label_1
_geom_angle_atom_site_label_2
_geom_angle_atom_site_label_3
_geom_angle
_geom_angle_site_symmetry_1
_geom_angle_site_symmetry_3
_geom_angle_publ_flag
O6 C1 C6 121.5(8) . . ?
O6 C1 C2 115.8(7) . . ?
C6 C1 C2 122.6(8) . . ?
C1 C2 C3 119.8(8) . . ?
C1 C2 H2 120.1 . . ?
C3 C2 H2 120.1 . . ?
N1 C3 C4 122.4(9) . . ?
N1 C3 C2 121.4(8) . . ?
C4 C3 C2 116.2(8) . . ?
C5 C4 C3 122.0(8) . . ?
C5 C4 H4 119.0 . . ?
C3 C4 H4 119.0 . . ?
C4 C5 C6 122.4(8) . . ?
C4 C5 H5 118.8 . . ?
C6 C5 H5 118.8 . . ?
C1 C6 C7 117.9(7) . . ?
C1 C6 C5 116.9(8) . . ?
C7 C6 C5 125.1(8) . . ?
C8 C7 C6 122.4(8) . . ?
C8 C7 H7 118.8 . . ?
C6 C7 H7 118.8 . . ?
C7 C8 C9 117.7(7) . . ?
C7 C8 C10 120.1(8) . . ?
C9 C8 C10 122.2(8) . . ?
O5 C9 O6 113.9(8) . . ?
O5 C9 C8 126.2(9) . . ?
O6 C9 C8 119.9(7) . . ?
C11 C10 C8 128.6(8) . . ?
C11 C10 H10 115.7 . . ?
C8 C10 H10 115.7 . . ?
C10 C11 C12 121.6(9) . . ?
C10 C11 H11 119.2 . . ?
C12 C11 H11 119.2 . . ?
C13 C12 C11 129.8(8) . . ?
C13 C12 H12 115.1 . . ?
C11 C12 H12 115.1 . . ?
C12 C13 C14 122.0(7) . . ?
C12 C13 C16 118.2(8) . . ?
C14 C13 C16 119.8(8) . . ?
O3 C14 O4 117.6(8) . . ?
O3 C14 C13 127.0(9) . . ?
O4 C14 C13 115.3(7) . . ?
O1 C15 O4 109.3(9) . . ?
O1 C15 C17 112.5(9) . . ?
O4 C15 C17 110.6(9) . . ?
O1 C15 C18 106.8(9) . . ?
O4 C15 C18 103.5(8) . . ?
C17 C15 C18 113.7(10) . . ?
O2 C16 O1 114.3(9) . . ?
O2 C16 C13 128.1(10) . . ?
O1 C16 C13 117.6(9) . . ?
C15 C17 H17A 109.5 . . ?
C15 C17 H17B 109.5 . . ?
H17A C17 H17B 109.5 . . ?
C15 C17 H17C 109.5 . . ?
H17A C17 H17C 109.5 . . ?
H17B C17 H17C 109.5 . . ?
C15 C18 H18A 109.5 . . ?
C15 C18 H18B 109.5 . . ?
H18A C18 H18B 109.5 . . ?
C15 C18 H18C 109.5 . . ?
H18A C18 H18C 109.5 . . ?
H18B C18 H18C 109.5 . . ?
C20 C19 N1 78.9(17) . . ?
C20 C19 H19A 115.4 . . ?
N1 C19 H19A 115.4 . . ?
C20 C19 H19B 115.4 . . ?
N1 C19 H19B 115.4 . . ?
H19A C19 H19B 112.4 . . ?
C19 C20 H20D 91.4 . . ?
H20A C20 H20D 85.9 . . ?
H20B C20 H20D 37.7 . . ?
H20C C20 H20D 146.9 . . ?
C19 C20 H20F 152.2 . . ?
H20A C20 H20F 97.4 . . ?
H20B C20 H20F 52.5 . . ?
H20C C20 H20F 66.2 . . ?
H20D C20 H20F 83.3 . . ?
H20D C20' H20E 109.5 . . ?
H20D C20' H20F 109.5 . . ?
H20E C20' H20F 109.5 . . ?
N1 C21 C22 112.3(11) . . ?
N1 C21 H21A 109.1 . . ?
C22 C21 H21A 109.1 . . ?
N1 C21 H21B 109.1 . . ?
C22 C21 H21B 109.1 . . ?
H21A C21 H21B 107.9 . . ?
C21 C22 H22A 109.5 . . ?
C21 C22 H22B 109.5 . . ?
H22A C22 H22B 109.5 . . ?
C21 C22 H22C 109.5 . . ?
H22A C22 H22C 109.5 . . ?
H22B C22 H22C 109.5 . . ?
C3 N1 C21 124.3(8) . . ?
C3 N1 C19 118.8(9) . . ?
C21 N1 C19 114.3(8) . . ?
C16 O1 C15 115.7(7) . . ?
C14 O4 C15 117.3(7) . . ?
C1 O6 C9 120.5(7) . . ?

loop_
_geom_torsion_atom_site_label_1
_geom_torsion_atom_site_label_2
_geom_torsion_atom_site_label_3
_geom_torsion_atom_site_label_4
_geom_torsion
_geom_torsion_site_symmetry_1
_geom_torsion_site_symmetry_2
_geom_torsion_site_symmetry_3
_geom_torsion_site_symmetry_4
_geom_torsion_publ_flag
O6 C1 C2 C3 179.6(10) . . . . ?
C6 C1 C2 C3 1.8(17) . . . . ?
C1 C2 C3 N1 177.4(12) . . . . ?
C1 C2 C3 C4 -0.6(16) . . . . ?
N1 C3 C4 C5 -179.6(12) . . . . ?
C2 C3 C4 C5 -1.6(16) . . . . ?
C3 C4 C5 C6 2.7(16) . . . . ?
O6 C1 C6 C7 3.4(14) . . . . ?
C2 C1 C6 C7 -179.0(10) . . . . ?
O6 C1 C6 C5 -178.5(9) . . . . ?
C2 C1 C6 C5 -0.8(15) . . . . ?
C4 C5 C6 C1 -1.5(15) . . . . ?
C4 C5 C6 C7 176.5(10) . . . . ?
C1 C6 C7 C8 -1.1(15) . . . . ?
C5 C6 C7 C8 -179.1(10) . . . . ?
C6 C7 C8 C9 -1.5(15) . . . . ?
C6 C7 C8 C10 176.4(9) . . . . ?
C7 C8 C9 O5 -176.4(11) . . . . ?
C10 C8 C9 O5 5.7(17) . . . . ?
C7 C8 C9 O6 1.9(14) . . . . ?
C10 C8 C9 O6 -175.9(9) . . . . ?
C7 C8 C10 C11 -173.8(11) . . . . ?
C9 C8 C10 C11 4.0(17) . . . . ?
C8 C10 C11 C12 177.1(10) . . . . ?
C10 C11 C12 C13 178.1(11) . . . . ?
C11 C12 C13 C14 2.8(17) . . . . ?
C11 C12 C13 C16 -179.6(11) . . . . ?
C12 C13 C14 O3 18.3(16) . . . . ?
C16 C13 C14 O3 -159.2(11) . . . . ?
C12 C13 C14 O4 -166.0(9) . . . . ?
C16 C13 C14 O4 16.4(14) . . . . ?
C12 C13 C16 O2 -16(2) . . . . ?
C14 C13 C16 O2 161.8(13) . . . . ?
C12 C13 C16 O1 166.0(10) . . . . ?
C14 C13 C16 O1 -16.4(16) . . . . ?
C4 C3 N1 C21 4(2) . . . . ?
C2 C3 N1 C21 -174.4(12) . . . . ?
C4 C3 N1 C19 -156.9(13) . . . . ?
C2 C3 N1 C19 25(2) . . . . ?
C22 C21 N1 C3 -82.9(16) . . . . ?
C22 C21 N1 C19 78.4(15) . . . . ?
C20 C19 N1 C3 -102.6(18) . . . . ?
C20 C19 N1 C21 95.0(18) . . . . ?
O2 C16 O1 C15 162.4(11) . . . . ?
C13 C16 O1 C15 -19.2(15) . . . . ?
O4 C15 O1 C16 51.8(12) . . . . ?
C17 C15 O1 C16 -71.5(11) . . . . ?
C18 C15 O1 C16 163.2(9) . . . . ?
O3 C14 O4 C15 -165.0(9) . . . . ?
C13 C14 O4 C15 18.9(12) . . . . ?
O1 C15 O4 C14 -52.3(11) . . . . ?
C17 C15 O4 C14 72.1(11) . . . . ?
C18 C15 O4 C14 -165.8(9) . . . . ?
C6 C1 O6 C9 -3.0(14) . . . . ?
C2 C1 O6 C9 179.2(9) . . . . ?
O5 C9 O6 C1 178.8(9) . . . . ?
C8 C9 O6 C1 0.2(14) . . . . ?

_diffrn_measured_fraction_theta_max 0.997
_diffrn_reflns_theta_full        24.00
_diffrn_measured_fraction_theta_full 0.997
_refine_diff_density_max         0.300
_refine_diff_density_min         -0.255
_refine_diff_density_rms         0.081