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Caption : fig. s1 digestion of bovine albumin in different concentrations of ionic liquids and sds, with 50 mm ammonium bicarbonate buffer as the control experiment.

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Caption : fig. s2 maldi-tof ms spectra of bsa product digested with trypsin (a) in 50 mm nh4hco3, (b) with addition of 1% (w/v) c12im-cl, (c) 2% (w/v) c12im-cl, (d) 3% (w/v) c12im-cl, and (e) 4% (w/v) c12im-cl.

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Caption : fig. s3 digestion of myoglobin monitored by sds-page and coomassie blue staining.

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Caption : fig. s4 total proteins extraction from hela cells in different solubilizer systems, ∗, p<0.05, two-tailed, unpaired t-test.