File Name : figure s1-s2.pdf Caption : figure s1. meta-regression of sbp and dbp change according to matched caffeine (a and b) for the 22 study arms. circles correspond to included studies and have magnitude proportional to the inverse of the square of se. 95% ci of the estimates are presented by dash gray lines. figure s2. meta-regression of sbp and dbp change according to the use of ambp (a and b) for the 22 study arms. circles correspond to included studies and have magnitude proportional to the inverse of the square of se. 95% ci of the estimates are presented by dash gray lines.