File Name : fig.s.1.tif Caption : fig. s.1: histograms depicting the intensity distributions in each replicate run of the four samples (co0 = control after 0 days, co7 = control after 7 days, mg7 = mg-incubated cells after 7 days, ti7 = ti-incubated cells after 7 days). the probability density function of the log10 protein lfq intensities is plotted. File Name : fig.s.2.tif Caption : fig. s.2: multi-scatter plot comparing the intensity distributions across all samples (co0 = control after 0 days, co7 = control after 7 days, mg7 = mg-incubated cells after 7 days, ti7 = ti-incubated cells after 7 days, with _x depicting the biological replicate for each condition). in the top left corner of each scatter-plot the pearson correlation is indicated. File Name : fig.s.3.tif Caption : fig. s.3: vulcano plots depicting the fold change and significance of each protein in samples after 7 days incubation in comparison to control at the beginning of the experiments (control0). red dots mark the proteins which are significantly regulated as determined by student’s t-test (fdr=0.01; s0= 0.1).