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["Details on the Absorption Model can be found at Sherer et al, Mol Inf. 2012. 31. 231"]
["Details on the PGP QSAR Models can be found at Ha et al. Curr Top Med Chem, 2007, 7, 15, 1525"]
["Permeability Bins were defined as Low < 5 nms/, 5 < Medium < 20 nm/s, High > 20 nm/s ",null,"PGP ER Bins were defined as Low < 3 , 3 < Medium < 6, High > 6 "]
[]
["Structure","QSAR Absorption (Papp)","QSAR PGP Human (BA:AB ratio)","CNS pMPO","CNS MPO","clogD7.4","cLogP (ACD_V12)","Hydrogen Bond Donor Count","Hydrogen Bond Acceptor Count","tPSA","Molecular Weight","Calculated pKa (Basic)","Calculated pKa (Acidic)"]
[null,"High","Low",0.87,5.57,2.48,2.94,1,5,68.28,356.44,5.53,6.35]
[null,"High","Low",0.87,5.82,1.93,2.56,1,6,71.53,357.43,6.5,6.34]
[null,"Low","Low",0.17,5.12,-3.44,-1.82,3,4,91.49,129.16,13.51,"NA"]
[null,"Low","Low",0.16,4,-2.33,-2.93,5,7,156.85,258.23,3.71,"NA"]
[null,"Medium","High",0.11,1.4,7.04,3.54,3,13,195.42,914.17,"NA",10.4]
[null,"Medium","Medium",0.44,4.1,1.23,3.78,2,6,87.45,469.56,9.13,11.19]
[null,"High","Low",0.58,5.63,1.33,0.44,0,2,32.67,174.2,2.73,"NA"]
[null,"Medium","Medium",0.41,3.82,0.34,3.88,2,7,89.36,507.6,9.13,12.37]
[null,"High","Low",0.55,4.6,2.83,3.14,3,3,60.69,228.24,"NA",9.22]
[null,"Medium","High",0.55,3.74,3.93,2.48,2,7,86.28,493.6,7.55,"NA"]
[null,"Medium","Low",0.34,2.88,1.47,6.5,3,5,97.37,360.39,9.1,0.46]
[null,"High","Low",0.33,3,6.35,6.22,0,5,84.23,505.69,"NA","NA"]
[null,"High","Low",0.62,6,0.78,0.62,0,4,52.6,144.13,"NA","NA"]
[null,"High","Low",0.57,5.5,1.3,1.2,2,4,79.63,215.21,3.08,9.86]
[null,"High","Low",0.62,5.36,0,"",0,0,29.08,281.11,"NA","NA"]
[null,"High","Low",0.77,5.83,1.21,1.39,1,3,46.53,166.17,"NA",8.18]
[null,"Medium","Low",0.17,3.3,1.28,2.08,8,11,197.36,458.37,"NA",7.75]
[null,"Medium","Low",0.48,3,10.23,10.23,0,4,52.6,583.72,"NA","NA"]
[null,"High","High",0.33,2.25,5.84,5.15,2,6,97.62,529.52,5.64,"NA"]
[null,"Medium","Medium",0.54,2.83,6.26,5.64,1,4,87.03,554.71,"NA","NA"]
[null,"Medium","Low",0.82,4,4.04,4.69,1,4,55.4,333.45,"NA",6.36]
[null,"Medium","Low",0.58,2.8,12.05,11.9,1,2,29.46,430.71,"NA",11.4]
[null,"Medium","Low",0.73,4.76,-0.79,1.42,2,3,50.94,211.33,9.47,"NA"]
[null,"Medium","High",0.46,3.09,3.21,3.03,2,8,99.17,576.62,8.55,12.72]
[null,"High","Medium",0.51,3.83,2.35,4.1,1,6,84.65,516.64,6.49,11.4]
[null,"High","Medium",0.63,4.05,3.38,3.9,1,5,85.05,450.56,5.6,6.99]
[null,"High","Low",0.73,6,0.85,1.91,0,4,62.98,324.3,"NA","NA"]
[null,"Medium","High",0.11,1.49,7.1,3.35,3,14,204.65,958.22,"NA",10.4]
[null,"Medium","HIgh",0.11,1.69,5.4,5.49,3,4,104.37,535.7,"NA",11.96]
[null,"High","Low",0.59,5.38,3.16,-0.1,1,8,92.29,401.49,"NA","NA"]
[null,"High","Low",0.6,5.3,1.54,1.67,1,5,105.95,321.33,0,0]
[null,"High","Low",0.55,4.78,2.9,3.08,0,2,26.3,190.24,"NA","NA"]
[null,"High","Low",0.6,3.34,1.71,6.8,1,4,75.43,463.61,"NA",3.72]
[null,"High","Low",0.85,5.44,3.09,2.7,1,3,61.09,309.4,"NA","NA"]
[null,"HIgh","Low",0.7,3.71,4.59,4.79,2,3,53.6,332.32,4.82,10.59]
[null,"High","Low",0.44,4.44,1.49,-0.87,1,10,115.41,436.46,4.8,"NA"]
[null,"High","Low",0.55,5.15,0,0.41,1,6,110.63,321.34,"NA",8.78]
[null,"Low","Medium",0.03,3,-3.27,0.87,5,12,213.12,540.46,3.76,"NA"]