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Caption : figure s1. tem images of cuo<sub>2</sub> nanodots at different magnifications.

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Caption : figure s2. (a) high resolution o 1s, (b) cu 2p, and (c) survey xps spectra of cuo<sub>2</sub> nanodots. (d) survey xps spectra of cuo<sub>2</sub> synthesized in the absence of pvp.

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Caption : figure s3. cumulative generation of h<sub>2</sub>o<sub>2</sub> from cuo<sub>2</sub> nanodots in different ph conditions, showing their acid-induced dissociation.

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Caption : figure s4. the ph changes of lb medium with culturing <i>e. coli</i>, <i>s. aureus</i>, mrsa and <i>p. aeruginos</i> within 24 h.

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Caption : figure s5. the initial blood glucose levels of stz-induced diabetic mice for different wound healing treatment.