{"text_format":"2","workbook":"xls","n_sheets":11,"sheets":["Table S1","Table S2","Table S3","Table S4","Table S5","Table S6","Table S7","Table S8","Table S9","Table S10","Table S11"],"not_rendered":{"charts":0,"images":0,"macros":0,"external_links":0,"defined_names":0,"comments":0,"pivot_tables":0},"unopened":[],"bounds":{"document_bytes":16777216,"sheet_cells":100000,"run_cost":"one","rows_first":2000,"rows_last":500,"rows_between":2000,"halvings":0,"cell_chars":16384,"cell_head_chars":4096},"cells_cut":0,"cells_raw":0,"read":"whole","date_system":"1900","formulas":"cached_only"}

{"sheet":"Table S1","index":0,"n_rows":8,"n_cols":3,"rows_kept":8,"cut":false,"hidden":false,"merged":[[0,0,0,1]],"flags":["formulas_cached_only"]}
["Table S1. Primer sequences used for real-time qPCR."]
["Gene","Direction","Primer sequence (5'-3')"]
["β-actin","Forward","ATATCGCTGCGCTGGTCGT"]
[null,"Reverse","CCTTCTGACCCATTCCCACC"]
["RORγt","Forward","TGACAGACATAGAGTACCTGG"]
[null,"Reverse","GTAGAAGGTCCTCCAGTCG"]
["T-bet","Forward","TGTTCCCAGCCGTTTCTACC"]
[null,"Reverse","GCTCGGAACTCCGCTTCATA"]

{"sheet":"Table S2","index":1,"n_rows":138,"n_cols":9,"rows_kept":138,"cut":false,"hidden":false,"merged":[],"flags":["formulas_cached_only"]}
["Table S2. MG compared to NG for significantly different metabolites (P<0.05, VIP>1 in the OPLS-DA)"]
["Metabolites name","Cluster by Chemrich","HMDB ID","Cluster by HMDB","Formula","Compound","m/z","Fold Change","P.value"]
["L-Threonine","amino acids","HMDB0000167","Amino acids, peptides, and analogues","C4H9NO3","1.00_120.0654m/z",120.0653832,1.8738,0.0080647]
["L-Valine","amino acids","HMDB0000883","Amino acids, peptides, and analogues","C5H11NO2","1.15_118.0865m/z",118.0864508,1.5217,0.0055736]
["Citrulline","amino acids","HMDB0000904","Amino acids, peptides, and analogues","C6H13N3O3","1.02_176.1033m/z",176.1033269,1.4861,0.011787]
["L-Tyrosine","amino acids, aromatic","HMDB0000158","Amino acids, peptides, and analogues","C9H11NO3","1.99_361.1399m/z",361.1398884,3.7311,0.04576]
["L-Phenylalanine","amino acids, aromatic","HMDB0000159","Amino acids, peptides, and analogues","C9H11NO2","3.47_164.0717m/z",164.0717159,1.3757,0.039006]
["L-Tryptophan","amino acids, aromatic","HMDB0000929","Indoles and derivatives","C11H12N2O2","3.67_204.0900n",203.0827148,1.6354,0.0006539]
["o-Tyrosine","amino acids, aromatic","HMDB0006050","Amino acids, peptides, and analogues","C9H11NO3","1.23_181.0746n",182.0818323,1.6312,0.00020736]
["L-Asparagine","amino acids, basic","HMDB0000168","Amino acids, peptides, and analogues","C4H8N2O3","0.98_132.0531n",133.0603602,3.3202,0.00032063]
["L-Lysine","amino acids, basic","HMDB0000182","Amino acids, peptides, and analogues","C6H14N2O2","0.88_147.1132m/z",147.1132414,1.9917,0.012829]
["Ornithine","amino acids, basic","HMDB0000214","Amino acids, peptides, and analogues","C5H12N2O2","0.88_133.0979m/z",133.0978564,2.5921,0.024267]
["L-Arginine","amino acids, basic","HMDB0000517","Amino acids, peptides, and analogues","C6H14N4O2","0.93_173.1042m/z",173.1041618,2.1413,0.005654]
["L-Glutamine","amino acids, basic","HMDB0000641","Amino acids, peptides, and analogues","C5H10N2O3","0.98_147.0767m/z",147.076743,1.5677,0.023161]
["D-Lysine","amino acids, basic","HMDB0003405","Amino acids, peptides, and analogues","C6H14N2O2","0.86_145.0978m/z",145.0977833,1.8746,0.00037796]
["D-Arginine","amino acids, basic","HMDB0003416","Amino acids, peptides, and analogues","C6H14N4O2","0.94_175.1196m/z",175.1195985,1.6808,0.022073]
["D-Glutamine","amino acids, basic","HMDB0003423","Amino acids, peptides, and analogues","C5H10N2O3","0.99_145.0616m/z",145.0616344,1.4889,0.0054079]
["L-Methionine","amino acids, sulfur","HMDB0000696","Amino acids, peptides, and analogues","C5H11NO2S","1.92_150.0587m/z",150.0587046,1.5042,0.012218]
["Methionine sulfoxide","amino acids, sulfur","HMDB0002005","Amino acids, peptides, and analogues","C5H11NO3S","1.05_166.0537m/z",166.0536606,1.951,0.044779]
["L-Homocysteic acid","amino acids, sulfur","HMDB0002205","Amino acids, peptides, and analogues","C4H9NO5S","0.90_365.0340m/z",365.0339519,3.1317,0.0016354]
["Racemethionine","amino acids, sulfur","HMDB0033951","Amino acids, peptides, and analogues","C5H11NO2S","1.19_150.0587m/z",150.0586502,1.3697,0.018831]
["3b,17b-Dihydroxyetiocholane","androstanols","HMDB0000369","Steroids and steroid derivatives","C19H32O2","10.70_293.2491m/z",293.2490851,0.46555,0.014164]
["3b,17a-Dihydroxy-5a-androstane","androstanols","HMDB0000412","Steroids and steroid derivatives","C19H32O2","13.05_293.2489m/z",293.2488572,0.39166,0.0012488]
["4-Hydroxybenzaldehyde","benzaldehydes","HMDB0011718","Carbonyl compounds","C7H6O2","4.32_121.0289m/z",121.0289083,2.8556,0.034629]
["D-Urobilinogen","bile pigments","HMDB0004158","Bilirubins","C33H42N4O6","10.28_591.3190m/z",591.319033,0.25651,0.00056242]
["Mesobilirubinogen","bile pigments","HMDB0001898","Bilirubins","C33H44N4O6","3.63_593.3344m/z",593.3343568,0.48628,0.001307]
["D-Urobilin","bile pigments","HMDB0004161","Bilirubins","C33H40N4O6","3.98_589.3039m/z",589.3038857,0.38528,0.0019329]
["L-Urobilin","bile pigments","HMDB0004159","Bilirubins","C33H46N4O6","5.60_594.3425n",595.3497956,0.43464,0.0021794]
["I-Urobilin","bile pigments","HMDB0004160","Bilirubins","C33H46N4O6","6.53_593.3335m/z",593.333507,0.35284,0.00011085]
["Isobutyryl-L-carnitine","carnitine","HMDB0000736","Acyl carnitines","C11H22NO4+","6.98_463.3042m/z",463.3041775,2.1962,0.00082486]
["L-Hexanoylcarnitine","carnitine","HMDB0000756","Acyl carnitines","C13H25NO4","11.20_517.3527m/z",517.3527243,1.6475,0.033738]
["Propionylcarnitine","carnitine","HMDB0000824","Acyl carnitines","C10H19NO4","2.44_218.1393m/z",218.1393123,0.44358,0.019924]
["Tetradecanoylcarnitine","carnitine","HMDB0005066","Acyl carnitines","C21H41NO4","10.84_372.3126m/z",372.3126262,0.29296,0.00029591]
["Hydroxyvalerylcarnitine","carnitine","HMDB0013132","Acyl carnitines","C12H25NO5","11.74_527.3567m/z",527.3567428,1.8571,0.024237]
["4a-Methylzymosterol","cholestadienols","HMDB0001217","Cholesterols and derivatives","C28H46O","10.92_421.3478m/z",421.3478391,0.35694,0.043053]
["5a-Cholestane-3a,7a,12a,25-tetrol","cholestanols","HMDB0000520","Glycerophospholipids","C27H48O4","7.22_459.3488m/z",459.3487518,0.31087,3.07e-05]
["3a,7a,12a-Trihydroxy-5b-cholestan-26-al","cholestanols","HMDB0003533","Bile acids, alcohols and derivatives","C27H46O4","5.00_457.3323m/z",457.3323003,0.51141,0.022896]
["4Alpha-hydroxymethyl-5alpha-cholesta-8-en-3beta-ol","cholesterol","HMDB0012173","Cholestane steroids","C28H48O2","10.92_439.3586m/z",439.3586198,0.33945,0.034172]
["3b-Hydroxy-5-cholenoic acid","cholic acids","HMDB0000308","Bile acids, alcohols and derivatives","C24H38O3","7.00_375.2910m/z",375.2910442,1.8834,0.025734]
["3a,7a,12b-Trihydroxy-5b-cholanoic acid","cholic acids","HMDB0000312","Bile acids, alcohols and derivatives","C24H40O5","6.64_407.2793m/z",407.2792637,1.8578,0.015716]
["2b,3a,7a,12a-Tetrahydroxy-5b-cholanoic acid","cholic acids","HMDB0000316","Bile acids, alcohols and derivatives","C24H40O6","4.65_424.2816n",423.2742763,1.4977,0.018228]
["1b,3a,12a-Trihydroxy-5b-cholanoic acid","cholic acids","HMDB0000326","Bile acids, alcohols and derivatives","C24H40O5","4.39_408.2897n",817.5844487,2.6722,0.0096314]
["3a,4b,12a-Trihydroxy-5b-cholanoic acid","cholic acids","HMDB0000330","Bile acids, alcohols and derivatives","C24H40O5","5.25_408.2866n",815.5676827,2.1916,0.0076041]
["3b,12a-Dihydroxy-5a-cholanoic acid","cholic acids","HMDB0000348","Bile acids, alcohols and derivatives","C24H40O4","5.42_785.5950m/z",785.5950294,7.2122,0.0096026]
["3a,7a-Dihydroxycoprostanic acid","cholic acids","HMDB0000359","Bile acids, alcohols and derivatives","C27H46O4","5.13_457.3330m/z",457.3329857,0.53612,0.015013]
["12a-Hydroxy-3-oxocholadienic acid","cholic acids","HMDB0000385","Bile acids, alcohols and derivatives","C24H34O4","4.79_387.2545m/z",387.254462,3.1239,0.0040044]
["7-Ketodeoxycholic acid","cholic acids","HMDB0000391","Bile acids, alcohols and derivatives","C24H38O5","5.22_407.2806m/z",407.2806436,1.7723,0.0066103]
["3,7-Dihydroxy-12-oxocholanoic acid","cholic acids","HMDB0000400","Bile acids, alcohols and derivatives","C24H38O5","6.20_405.2636m/z",405.2635936,1.8293,0.019701]
["3-Oxo-4,6-choladienoic acid","cholic acids","HMDB0000476","Bile acids, alcohols and derivatives","C24H34O3","4.67_371.2595m/z",371.2595099,1.8256,0.012778]
["3-Oxocholic acid","cholic acids","HMDB0000502","Bile acids, alcohols and derivatives","C24H38O5","5.52_406.2709n",405.2635908,2.1536,0.001651]
["7a-Hydroxy-3-oxo-5b-cholanoic acid","cholic acids","HMDB0000503","Bile acids, alcohols and derivatives","C24H38O4","4.67_391.2857m/z",391.2857206,1.6046,0.010853]
["Allocholic acid","cholic acids","HMDB0000505","Bile acids, alcohols and derivatives","C24H40O5","6.16_408.2868n",815.5686408,1.8673,0.044067]
["Cholic acid","cholic acids","HMDB0000619","Bile acids, alcohols and derivatives ","C24H40O5","5.24_408.2891n",817.5846359,2.3596,0.047222]
["Deoxycholic acid","cholic acids","HMDB0000626","Bile acids, alcohols and derivatives","C24H40O4","5.30_371.2594m/z",371.2594374,2.0965,0.041793]
["Hyocholic acid","cholic acids","HMDB0000760","Bile acids, alcohols and derivatives","C24H40O5","6.62_503.3362m/z",503.3362243,27.021,0.032216]
["Cholic acid glucuronide","cholic acids","HMDB0002577","Steroids and steroid derivatives","C30H48O11","3.98_607.3143m/z",607.3142831,0.38452,0.0027869]
["7a,12a-Dihydroxy-5a-cholestan-3-one","cholic acids","HMDB0006886","Cholestane steroids","C27H46O3","7.24_441.3379m/z",441.33793,0.43721,0.0012656]
["7a,12a-Dihydroxy-5b-cholestan-3-one","cholic acids","HMDB0006887","Cholesterols and derivatives","C27H46O3","6.78_441.3380m/z",441.3380457,0.50585,0.010339]
["Aldosterone 18-glucuronide","cholic acids","HMDB0010345","Steroidal glycosides","C27H36O11","6.02_535.2229m/z",535.2229446,2.1986,0.0023038]
["Deoxycholic acid 3-glucuronide","cholic acids","HMDB0002596","Steroids and steroid derivatives","C30H48O10","3.63_591.3193m/z",591.3192533,0.4099,0.00022615]
["Cinnamic acid","cinnamates","HMDB0000567","Cinnamic acids","C9H8O2","3.47_147.0449m/z",147.0449076,1.8388,0.036789]
["trans-Cinnamic acid","cinnamates","HMDB0000930","Cinnamic acids ","C9H8O2","3.26_149.0601m/z",149.0601349,2.7838,6.8e-05]
["trans-Ferulic acid","coumaric acids","HMDB0000954","Hydroxycinnamic acids and derivatives","C10H10O4","4.37_193.0505m/z",193.0504921,0.46433,0.00032038]
["Hydroferulic acid","coumaric acids","HMDB0062121","Phenylpropanoic acids","C10H12O4","4.32_195.0663m/z",195.066297,0.26455,0.010815]
["Nutriacholic acid","deoxycholic acid","HMDB0000467","Bile acids, alcohols and derivatives","C24H38O4","5.24_391.2851m/z",391.2850994,1.6125,0.045905]
["Chenodeoxycholic acid","deoxycholic acid","HMDB0000518","Bile acids, alcohols and derivatives ","C24H40O4","7.97_391.2847m/z",391.2846552,1.9073,0.017786]
["Lithocholic acid glycine conjugate","deoxycholic acid","HMDB0000698","Bile acids, alcohols and derivatives","C26H43NO4","6.57_434.3287m/z",434.32866,1.6099,0.046862]
["MG(0:0/18:3(6Z,9Z,12Z)/0:0)","diglycerides","HMDB0011539","Lineolic acids and derivatives ","C21H36O4","9.85_352.2628n",353.2700279,0.38979,0.0047686]
["MG(0:0/18:3(9Z,12Z,15Z)/0:0)","diglycerides","HMDB0011540","Lineolic acids and derivatives","C21H36O4","8.32_353.2702m/z",353.2701555,0.35299,0.0034888]
["MG(16:1(9Z)/0:0/0:0)","diglycerides","HMDB0011565","Monoradylglycerols ","C19H36O4","10.35_329.2703m/z",329.2703135,0.17398,0.025651]
["MG(22:6(4Z,7Z,10Z,13Z,16Z,19Z)/0:0/0:0)","diglycerides","HMDB0011587","Monoradylglycerols ","C25H38O4","10.55_402.2785n",403.2857508,0.351,0.02275]
["MG(18:3(9Z,12Z,15Z)/0:0/0:0)","diglycerides","HMDB0011570","Lineolic acids and derivatives","C21H36O4","7.14_353.2702m/z",353.2702047,0.10479,0.0013097]
["12,13-Epoxy-9,15-octadecadienoic acid","DiHOME","HMDB0031088","Unsaturated fatty acids","C19H32O3","11.17_308.2365n",309.243823,0.38884,0.0012308]
["Ricinoleic acid","DiHOME","HMDB0034297","unsaturated fatty acid","C18H34O3","11.77_298.2506n",297.2433531,4.1588,0.00021942]
["(S)-9-Hydroxy-10-undecenoic acid","DiHOME","HMDB0032662","Unsaturated fatty acids","C11H20O3","12.25_399.2747m/z",399.2746517,0.32802,0.0018058]
["9,10-DHOME","DiHOME","HMDB0004704","Unsaturated fatty acids","C18H34O4","7.62_313.2380m/z",313.2379984,0.41461,0.036737]
["12,13-DHOME","DiHOME","HMDB0004705","Unsaturated fatty acids","C18H34O4","7.46_313.2379m/z",313.2378608,0.19452,0.026295]
["Riboflavin","flavins","HMDB0000244","Alloxazines and isoalloxazines ","C17H20N4O6","3.43_377.1477m/z",377.1476995,1.8065,0.0014605]
["D-Glucuronic acid","glucuronates","HMDB0000127","Carbohydrates and carbohydrate conjugates","C6H10O7","1.05_193.0348m/z",193.0348417,0.18207,0.00058548]
["L-Glutamic acid","glutamates","HMDB0000148","Amino acids, peptides, and analogues","C5H9NO4","1.02_148.0609m/z",148.0608581,1.4686,0.015349]
["N-Acetylglutamic acid","glutamates","HMDB0001138","Amino acids, peptides, and analogues","C7H11NO5","2.01_189.0642n",190.0714906,1.9988,0.023692]
["MG(18:2(9Z,12Z)/0:0/0:0)","glycerides","HMDB0011568","Lineolic acids and derivatives ","C21H38O4","10.84_354.2784n",355.2856599,0.29457,0.00016032]
["MG(0:0/18:1(9Z)/0:0)","glycerides","HMDB0011537","Monoradylglycerols","C21H40O4","11.80_357.3015m/z",357.3015011,0.32074,0.001134]
["MG(18:1(9Z)/0:0/0:0)","glycerides","HMDB0011567","Glycerolipids","C21H40O4","12.04_356.2941n",357.3013572,0.73494,0.032176]
["MG(16:0/0:0/0:0)","glycerides","HMDB0011564","Glycerolipids","C19H38O4","11.51_331.2857m/z",331.2857408,0.62476,0.02567]
["(R)-2-Hydroxyhexadecanoic acid","glycerides","HMDB0031057","Fatty acids and conjugates","C16H32O3","12.36_271.2280m/z",271.2279853,1.6649,0.0074031]
["PC(20:4(8Z,11Z,14Z,17Z)/20:2(11Z,14Z))","glycerophospholipids","HMDB0008473","Glycerophospholipids","C48H84NO8P","4.39_834.6113m/z",834.6113124,2.5028,0.0074319]
["PS(22:6(4Z,7Z,10Z,13Z,16Z,19Z)/18:0)","glycerophospholipids","HMDB0012444","Glycerophospholipids","C46H78NO10P","4.39_836.5588m/z",836.5587934,3.2531,0.0073278]
["PC(o-18:1(9Z)/18:0)","glycerophospholipids","HMDB0013427","Glycerophospholipids","C27H56NO6P","11.74_522.4017m/z",522.401678,1.7591,0.019528]
["L-Histidine","histidine","HMDB0000177","Amino acids, peptides, and analogues","C6H9N3O2","0.92_155.0697n",156.0769331,2.1466,0.00030132]
["Kynurenic acid","hydroxyquinolines","HMDB0000715","Quinolines and derivatives","C10H7NO3","3.80_188.0351m/z",188.0351259,0.63687,0.01229]
["Imidazolepropionic acid","imidazoles","HMDB0002271","Imidazoles ","C6H8N2O2","1.13_141.0661m/z",141.0661188,0.42143,0.034611]
["Indoleacrylic acid","indoles","HMDB0000734","Indoles","C11H9NO2","3.37_188.0711m/z",188.0711041,1.7849,0.0098538]
["1H-Indole-3-carboxaldehyde","indoles","HMDB0029737","Indoles","C9H7NO","3.37_146.0598m/z",146.0598255,30.17,0.0002891]
["D-Tryptophan","indoles","HMDB0013609","Indoles and derivatives","C11H12N2O2","3.37_204.0884n",205.0956497,1.587,0.0045966]
["2-Keto-glutaramic acid","ketoglutaric acids","HMDB0001552","Short-chain keto acids and derivatives","C5H7NO4","1.78_289.0672m/z",289.067174,0.5479,0.021622]
["LysoPC(18:2(9Z,12Z))","lysophospholipids","HMDB0010386","Glycerophospholipids","C27H53NO7P+","8.07_533.3472m/z",533.3472207,294.24,0.0095506]
["LysoPE(0:0/14:0)","lysophospholipids","HMDB0011470","Glycerophospholipids","C19H40NO7P","7.17_424.2460m/z",424.2459768,0.53241,0.011968]
["LysoPE(14:0/0:0)","lysophospholipids","HMDB0011500","Glycerophospholipids","C19H40NO7P","6.21_425.2555n",426.2627286,0.61049,0.039695]
["2-Oleoylglycerophosphocholine","lysophospholipids","HMDB0061701","Glycerophospholipids","C26H53NO7P+","5.77_521.3473m/z",521.3472968,0.35673,0.01463]
["LysoPE(0:0/18:2(9Z,12Z))","NewCluster_2","HMDB0011477","Glycerophospholipids","C23H44NO7P","7.02_478.2943m/z",478.2942939,0.30127,0.017879]
["LysoPE(0:0/20:3(11Z,14Z,17Z))","NewCluster_2","HMDB0011484","Glycerophospholipids","C25H46NO7P","8.98_502.2932m/z",502.2932237,0.25867,0.0092373]
["LysoPE(0:0/20:3(5Z,8Z,11Z))","NewCluster_2","HMDB0011485","Glycerophospholipids","C25H46NO7P","8.72_502.2939m/z",502.2939247,0.24149,0.033174]
["LysoPE(18:2(9Z,12Z)/0:0)","NewCluster_2","HMDB0011507","Glycerophospholipids","C23H44NO7P","8.01_476.2774m/z",476.2773537,0.26731,0.024306]
["LysoPE(0:0/20:4(5Z,8Z,11Z,14Z))","NewCluster_2","HMDB0011487","Glycerophospholipids","C25H44NO7P","8.36_500.2767m/z",500.2767368,0.20782,0.0025364]
["3-Hydroxytetradecanedioic acid","O=FA_14_1","HMDB0000394","Fatty acids and conjugates","C14H26O5","12.22_547.3485m/z",547.348509,1.8012,0.042813]
["3-Oxohexadecanoic acid","O=FA_16_1","HMDB0010733","Fatty acids and conjugates","C16H30O3","10.35_269.2113m/z",269.2113223,0.42024,0.0052373]
["3-Hydroxydodecanoic acid","OH-FA_12_0_1","HMDB0000387","Medium-chain hydroxy acids and derivatives","C12H24O3","0.92_239.1627m/z",239.1626938,0.53832,0.012402]
["Oleamide","oleic acids","HMDB0002117","Fatty amides","C18H35NO","6.14_282.2805m/z",282.2804634,1.8084,0.00046529]
["4-Hydroxybenzoic acid","parabens","HMDB0000500","Benzoic acids and derivatives","C7H6O3","4.00_137.0241m/z",137.024089,1.8778,0.01091]
["Picolinic acid","picolinic acids","HMDB0002243","Picolinic acid","C6H5NO2","1.27_124.0389m/z",124.0388846,0.66883,0.028073]
["L-Pipecolic acid","pipecolic acids","HMDB0000716","Amino acids, peptides, and analogues","C6H11NO2","0.88_130.0865m/z",130.0865497,2.006,0.0092025]
["Alpha-Linolenoyl ethanolamide","polyunsaturated alkamides","HMDB0013624","Amines","C20H35NO2","10.88_321.2683n",322.2755269,0.60239,0.013294]
["Adenosine","purine nucleosides","HMDB0000050","Purine nucleosides","C10H13N5O4","3.03_266.0894m/z",266.0894282,1.5758,0.036554]
["Uridine","pyrimidine nucleosides","HMDB0000296","Pyrimidine nucleosides","C9H12N2O6","1.78_243.0620m/z",243.0619953,0.51407,0.0084934]
["Pyroglutamic acid","pyrrolidines","HMDB0000267","Amino acids, peptides, and analogues","C5H7NO3","1.00_130.0499m/z",130.0499466,1.5063,0.019226]
["Glutarylglycine","pyrrolidines","HMDB0000590","Amino acids, peptides, and analogues","C7H11NO5","1.85_188.0564m/z",188.0563684,1.6669,0.047952]
["Pyruvic acid","pyruvates","HMDB0000243","Alpha-keto acids and derivatives","C3H4O3","1.25_87.0083m/z",87.00825967,0.37284,0.0034946]
["(R)-lipoic acid","Saturated FA","HMDB0001451","Lipoic acids and derivatives","C8H14O2S2","0.92_207.0512m/z",207.0511944,2.0083,0.031037]
["Leukotriene E3","srs-a","HMDB0002355","Eicosanoids","C23H39NO5S","3.87_440.2514m/z",440.2513603,2.5186,0.016356]
["Stearoylethanolamide","stearic acids","HMDB0013078","Amines","C20H41NO2","7.52_328.3228m/z",328.3228249,1.8665,0.0058348]
["N-Decanoylglycine","stearic acids","HMDB0013267","Amino acids, peptides, and analogues","C12H23NO3","10.42_457.3316m/z",457.3315621,0.5022,0.024791]
["trans-Piceid","stilbenes","HMDB0030564","Stilbene glycosides","C20H22O8","4.53_389.1243m/z",389.1243371,0.33683,0.037028]
["Ascorbic acid","sugar acids","HMDB0000044","Furanones","C6H8O6","1.12_351.0559m/z",351.0558661,0.52939,0.030998]
["Linoleic acid","UnSaturated FA","HMDB0000673","Unsaturated fatty acids","C18H32O2","10.35_281.2491m/z",281.2490994,4.7874,0.00032963]
["Alpha-Linolenic acid","UnSaturated FA","HMDB0001388","Unsaturated fatty acids","C18H30O2","11.88_279.2335m/z",279.2334507,0.33617,0.0074041]
["10Z-Heptadecenoic acid","UnSaturated FA","HMDB0060038","Unsaturated fatty acids","C17H32O2","10.96_269.2489m/z",269.2489125,0.11125,0.0011852]
["Palmitoleic acid","UnSaturated FA","HMDB0003229","Unsaturated fatty acid","C16H30O2","12.82_253.2181m/z",253.2180823,0.19298,0.031576]
["13-OxoODE","UnSaturated FA","HMDB0004668","Unsaturated fatty acids","C18H30O3","8.49_293.2122m/z",293.212211,0.34006,0.0080679]
["Gamma-Linolenic acid","UnSaturated FA","HMDB0003073","Unsaturated fatty acids","C18H30O2","12.44_277.2172m/z",277.2171756,0.60469,0.00047016]
["Linoelaidic acid","UnSaturated FA","HMDB0006270","Unsaturated fatty acids","C18H32O2","11.82_281.2489m/z",281.2489059,0.68766,0.016489]
["Docosapentaenoic acid","UnSaturated FA","HMDB0006528","Unsaturated fatty acids","C22H34O2","5.13_353.2479m/z",353.2479342,2.34,0.0014869]
["9-HOTE","UnSaturated FA","HMDB0010224","Unsaturated fatty acid","C18H30O3","10.14_293.2123m/z",293.2122982,0.5474,0.038465]
["Oleic acid","UnSaturated FA","HMDB0000207","Unsaturated fatty acids","C18H34O2","12.77_283.2643m/z",283.2643339,0.57218,0.0012826]
["(Z)-9-Heptadecenoic acid","UnSaturated FA","HMDB0031046","Unsaturated fatty acids","C17H32O2","13.81_269.2492m/z",269.2491981,0.0046368,0.00063335]
["(Z)-13-Hexadecenoic acid","UnSaturated FA","HMDB0035877","Unsaturated fatty acids","C16H30O2","8.58_255.2333m/z",255.2332839,0.54256,0.030553]
["Uridine 5'-monophosphate","uracil nucleotides","HMDB0000288","Pyrimidine ribonucleotides","C9H13N2O9P","1.49_323.0279m/z",323.027937,0.26525,0.042414]
["Uric acid","xanthines","HMDB0000289","Purines and purine derivatives","C5H4N4O3","1.17_167.0204m/z",167.0204068,3.3437,0.012808]

{"sheet":"Table S3","index":2,"n_rows":139,"n_cols":23,"rows_kept":139,"cut":false,"hidden":false,"merged":[[0,0,0,9]],"flags":["formulas_cached_only"]}
["Table S3. Chemical similarity enrichment analysis of significantly different metabolites between MG and NG."]
["Compound.Name","InChiKeys","Pubchem.ID","SMILES","P.value","foldchange","CID","ClusterNumber","xlogp","ClusterLabel","TreeLabels","FDR",null,"Cluster name","Cluster size","p-values","FDR","Key compound","Altered metabolites","Increased","Decreased","Increased ratio","Altered Ratio"]
["2-Keto-glutaramic acid","COJBGNAUUSNXHX-UHFFFAOYSA-N","48","C(CC(=O)N)C(=O)C(=O)O",0.022,0.55,"48",3,-1.784,"ketoglutaric acids","",0.97,null,"cholic acids",22,2.2e-20,1.9e-19,"Deoxycholic acid 3-glucuronide",22,17,5,0.8,1]
["4-Hydroxybenzaldehyde","RGHHSNMVTDWUBI-UHFFFAOYSA-N","126","C1=CC(=CC=C1C=O)O",0.035,2.9,"126",36,0.349,"benzaldehydes","",0.97,null,"UnSaturated FA",12,2.2e-20,1.9e-19,"Linoleic acid",12,2,10,0.2,1]
["4-Hydroxybenzoic acid","FJKROLUGYXJWQN-UHFFFAOYSA-N","135","C1=CC(=CC=C1C(=O)O)O",0.011,1.9,"135",36,0.268,"parabens","",0.78,null,"bile pigments",5,4.9e-14,2.8e-13,"I-Urobilin",5,0,5,0,1]
["N-Acetylglutamic acid","RFMMMVDNIPUKGG-UHFFFAOYSA-N","185","CC(=O)NC(CCC(=O)O)C(=O)O",0.024,2,"185",9,-0.907,"glutamates","",0.97,null,"amino acids, basic",8,1.2e-13,5.1e-13,"L-Asparagine",8,8,0,1,1]
["Methionine sulfoxide","QEFRNWWLZKMPFJ-UHFFFAOYSA-N","847","CS(=O)CCC(C(=O)O)N",0.045,2,"847",10,-3.882,"methionine","",0.97,null,"diglycerides",5,1.1e-08,3.8e-08,"MG(18:3(9Z,12Z,15Z)/0:0/0:0)",5,0,5,0,1]
["D-Lysine","KDXKERNSBIXSRK-UHFFFAOYSA-N","866","C(CCN)C[C@H](C(=O)O)N",0.00038,1.9,"866",25,-2.949,"amino acids, basic","a",0.047,null,"glycerides",5,3.4e-08,9.3e-08,"MG(18:2(9Z,12Z)/0:0/0:0)",5,1,4,0.2,1]
["Racemethionine","FFEARJCKVFRZRR-UHFFFAOYSA-N","876","CSCCC(C(=O)O)N",0.019,1.4,"876",10,-1.853,"methionine","",0.94,null,"plasmalogens",5,4e-08,9.3e-08,"LysoPE(0:0/20:4(5Z,8Z,11Z,14Z))",5,0,5,0,1]
["Picolinic acid","SIOXPEMLGUPBBT-UHFFFAOYSA-N","1018","C1=CC=NC(=C1)C(=O)O",0.028,0.67,"1018",38,-0.102,"picolinic acids","b",0.97,null,"carnitine",5,4.4e-08,9.3e-08,"Tetradecanoylcarnitine",5,3,2,0.6,1]
["Pyruvic acid","LCTONWCANYUPML-UHFFFAOYSA-N","1060","CC(=O)C(=O)O",0.0035,0.37,"1060",24,-0.426,"pyruvates","",0.34,null,"DiHOME",5,6.7e-08,1.3e-07,"Ricinoleic acid",5,1,4,0.2,1]
["Uric acid","LEHOTFFKMJEONL-UHFFFAOYSA-N","1175","C12=C(NC(=O)N1)NC(=O)NC2=O",0.013,3.3,"1175",11,-1.191,"xanthines","",0.82,null,"indoles",3,9.6e-07,1.6e-06,"1H-Indole-3-carboxaldehyde",3,3,0,1,1]
["Kynurenic acid","HCZHHEIFKROPDY-UHFFFAOYSA-N","3845","C1=CC=C2C(=C1)C(=O)C=C(N2)C(=O)O",0.012,0.64,"3845",38,0.665,"hydroxyquinolines","b",0.82,null,"amino acids",3,1.6e-06,2.5e-06,"L-Valine",3,3,0,1,1]
["L-Glutamine","ZDXPYRJPNDTMRX-VKHMYHEASA-N","5961","C(CC(=O)N)[C@@H](C(=O)O)N",0.023,1.6,"5961",3,-4.077,"amino acids, basic","",0.97,null,"cinnamates",4,1.8e-06,2.6e-06,"trans-Cinnamic acid",4,2,2,0.5,1]
["L-Lysine","KDXKERNSBIXSRK-YFKPBYRVSA-N","5962","C(CCN)C[C@@H](C(=O)O)N",0.013,2,"5962",25,-2.949,"amino acids, basic","a",0.82,null,"lysophospholipids",4,2.5e-06,3.2e-06,"LysoPC(18:2(9Z,12Z))",4,1,3,0.2,1]
["Uridine","DRTQHJPVMGBUCF-XVFCMESISA-N","6029","C1=CN(C(=O)NC1=O)[C@H]2[C@@H]([C@@H]([C@H](O2)CO)O)O",0.0085,0.51,"6029",11,-2.117,"pyrimidine nucleosides","",0.67,null,"amino acids, aromatic",4,4.4e-06,5.3e-06,"o-Tyrosine",4,4,0,1,1]
["Uridine 5'-monophosphate","DJJCXFVJDGTHFX-XVFCMESISA-N","6030","C1=CN(C(=O)NC1=O)[C@H]2[C@@H]([C@@H]([C@H](O2)COP(=O)(O)O)O)O",0.042,0.27,"6030",11,-3.775,"uracil nucleotides","",0.97,null,"glycerophospholipids",3,7.4e-06,8.4e-06,"PS(22:6(4Z,7Z,10Z,13Z,16Z,19Z)/18:0)",3,3,0,1,1]
["L-Tyrosine","OUYCCCASQSFEME-QMMMGPOBSA-N","6057","C1=CC(=CC=C1C[C@@H](C(=O)O)N)O",0.046,3.7,"6057",21,-2.711,"amino acids, aromatic","",0.97,null,"methionine",3,9e-05,9.5e-05,"L-Homocysteic acid",3,3,0,1,1]
["(R)-lipoic acid","AGBQKNBQESQNJD-SSDOTTSWSA-N","6112","C1CSS[C@@H]1CCCCC(=O)O",0.031,2,"6112",12,2.072,"Saturated FA","",0.97,null,"deoxycholic acid",3,0.0001,0.0001,"Chenodeoxycholic acid",3,3,0,1,1]
["L-Methionine","FFEARJCKVFRZRR-BYPYZUCNSA-N","6137","CSCC[C@@H](C(=O)O)N",0.012,1.5,"6137",10,-1.853,"amino acids, sulfur","",0.82]
["L-Phenylalanine","COLNVLDHVKWLRT-QMMMGPOBSA-N","6140","C1=CC=C(C=C1)C[C@@H](C(=O)O)N",0.039,1.4,"6140",21,-1.575,"amino acids, aromatic","",0.97]
["Ornithine","AHLPHDHHMVZTML-BYPYZUCNSA-N","6262","C(C[C@@H](C(=O)O)N)CN",0.024,2.6,"6262",3,-3.307,"amino acids, basic","",0.97]
["L-Asparagine","DCXYFEDJOCDNAF-REOHCLBHSA-N","6267","C([C@@H](C(=O)O)N)C(=O)N",0.00032,3.3,"6267",3,-4.435,"amino acids, basic","",0.04]
["L-Histidine","HNDVDQJCIGZPNO-YFKPBYRVSA-N","6274","C1=C(NC=N1)C[C@@H](C(=O)O)N",0.0003,2.1,"6274",33,-3.429,"histidine","",0.038]
["L-Valine","KZSNJWFQEVHDMF-BYPYZUCNSA-N","6287","CC(C)[C@@H](C(=O)O)N",0.0056,1.5,"6287",24,-2.169,"amino acids","",0.5]
["L-Threonine","AYFVYJQAPQTCCC-GBXIJSLDSA-N","6288","C[C@H]([C@@H](C(=O)O)N)O",0.0081,1.9,"6288",24,-3.496,"amino acids","",0.66]
["L-Tryptophan","QIVBCDIJIAJPQS-VIFPVBQESA-N","6305","C1=CC=C2C(=C1)C(=CN2)C[C@@H](C(=O)O)N",0.00065,1.6,"6305",5,-2.023,"amino acids, aromatic","",0.076]
["L-Arginine","ODKSFYDXXFIFQN-BYPYZUCNSA-N","6322","C(C[C@@H](C(=O)O)N)CN=C(N)N",0.0057,2.1,"6322",26,-3.585,"amino acids, basic","c",0.51]
["Pyroglutamic acid","ODHCTXKNWHHXJC-VKHMYHEASA-N","7405","C1CC(=O)N[C@@H]1C(=O)O",0.019,1.5,"7405",9,-0.827,"pyrrolidinones","",0.94]
["D-Tryptophan","QIVBCDIJIAJPQS-SECBINFHSA-N","9060","C1=CC=C2C(=C1)C(=CN2)C[C@H](C(=O)O)N",0.0046,1.6,"9060",5,-2.023,"indoles","",0.43]
["Citrulline","RHGKLRLOHDJJDR-BYPYZUCNSA-N","9750","C(C[C@@H](C(=O)O)N)CNC(=O)N",0.012,1.5,"9750",9,-3.909,"amino acids","",0.82]
["Chenodeoxycholic acid","RUDATBOHQWOJDD-BSWAIDMHSA-N","10133","C[C@H](CCC(=O)O)[C@H]1CC[C@@H]2[C@@]1(CC[C@H]3[C@H]2[C@@H](C[C@H]4[C@@]3(CC[C@H](C4)O)C)O)C",0.018,1.9,"10133",4,6.178,"deoxycholic acid","",0.94]
["1H-Indole-3-carboxaldehyde","OLNJUISKUQQNIM-UHFFFAOYSA-N","10256","C1=CC=C2C(=C1)C(=CN2)C=O",0.00029,30,"10256",5,1.466,"indoles","",0.037]
["Hydroferulic acid","BOLQJTPHPSDZHR-UHFFFAOYSA-N","14340","COC1=C(O)C=CC(CCC(O)=O)=C1",0.011,0.26,"14340",22,0.258,"cinnamates","",0.78]
["Mesobilirubinogen","OBHRVMZSZIDDEK-UHFFFAOYSA-N","26818","CCC1=C(C(=O)NC1CC2=C(C(=C(N2)CC3=C(C(=C(N3)CC4C(=C(C(=O)N4)CC)C)C)CCC(=O)O)CCC(=O)O)C)C",0.0013,0.49,"26818",31,1.319,"bile pigments","",0.14]
["Stearoylethanolamide","OTGQIQQTPXJQRG-UHFFFAOYSA-N","27902","CCCCCCCCCCCCCCCCCC(=O)NCCO",0.0058,1.9,"27902",13,7.789,"stearic acids","d",0.51]
["L-Glutamic acid","WHUUTDBJXJRKMK-VKHMYHEASA-N","33032","C(CC(=O)O)[C@@H](C(=O)O)N",0.015,1.5,"33032",3,-3.349,"glutamates","",0.87]
["Adenosine","OIRDTQYFTABQOQ-KQYNXXCUSA-N","60961","C1=NC2=C(C(=N1)N)N=CN2[C@H]3[C@@H]([C@@H]([C@H](O3)CO)O)O",0.037,1.6,"60961",11,-2.367,"purine nucleosides","",0.97]
["Imidazolepropionic acid","ZCKYOWGFRHAZIQ-UHFFFAOYSA-N","70630","C1=C(NC=N1)CCC(=O)O",0.035,0.42,"70630",33,-0.432,"imidazoles","",0.97]
["D-Arginine","ODKSFYDXXFIFQN-SCSAIBSYSA-N","71070","C(C[C@H](C(=O)O)N)CN=C(N)N",0.022,1.7,"71070",26,-3.585,"amino acids, basic","c",0.97]
["o-Tyrosine","WRFPVMFCRNYQNR-UHFFFAOYSA-N","91482","C1=CC=C(C(=C1)CC(C(=O)O)N)O",0.00021,1.6,"91482",21,-2.5,"amino acids, aromatic","",0.028]
["(R)-2-Hydroxyhexadecanoic acid","JGHSBPIZNUXPLA-UHFFFAOYSA-N","92836","CCCCCCCCCCCCCCC(C(=O)O)O",0.0074,1.7,"92836",37,6.595,"glycerides","",0.63]
["3b-Hydroxy-5-cholenoic acid","HIAJCGFYHIANNA-QIZZZRFXSA-N","92997","C[C@H](CCC(=O)O)[C@H]1CC[C@@H]2[C@@]1(CC[C@H]3[C@H]2CC=C4[C@@]3(CC[C@@H](C4)O)C)C",0.026,1.9,"92997",23,6.998,"cholic acids","e",0.97]
["3-Hydroxydodecanoic acid","MUCMKTPAZLSKTL-UHFFFAOYSA-N","94216","CCCCCCCCCC(CC(=O)O)O",0.012,0.54,"94216",12,3.842,"OH-FA_12_0_1","",0.82]
["3,7-Dihydroxy-12-oxocholanoic acid","MIHNUBCEFJLAGN-DMMBONCOSA-N","94235","C[C@H](CCC(=O)O)[C@H]1CC[C@@H]2[C@@]1(C(=O)C[C@H]3[C@H]2[C@@H](C[C@H]4[C@@]3(CC[C@H](C4)O)C)O)C",0.02,1.8,"94235",6,3.486,"cholic acids","f",0.94]
["D-Glucuronic acid","AEMOLEFTQBMNLQ-AQKNRBDQSA-N","94715","[C@@H]1([C@@H]([C@H](O[C@@H]([C@@H]1O)O)C(=O)O)O)O",0.00059,0.18,"94715",39,-1.54,"glucuronates","g",0.07]
["Propionylcarnitine","UFAHZIUFPNSHSL-UHFFFAOYSA-N","107738","CCC(=O)OC(CC(=O)[O-])C[N+](C)(C)C",0.02,0.44,"107738",20,-0.748,"carnitine","h",0.94]
["Lithocholic acid glycine conjugate","XBSQTYHEGZTYJE-OETIFKLTSA-N","115245","C[C@H](CCC(=O)NCC(=O)O)[C@H]1CC[C@@H]2[C@@]1(CC[C@H]3[C@H]2CC[C@H]4[C@@]3(CC[C@H](C4)O)C)C",0.047,1.6,"115245",14,7.435,"deoxycholic acid","",0.97]
["D-Glutamine","ZDXPYRJPNDTMRX-GSVOUGTGSA-N","145815","C(CC(=O)N)[C@H](C(=O)O)N",0.0054,1.5,"145815",3,-4.077,"amino acids, basic","",0.49]
["Aldosterone 18-glucuronide","OMRIQCUHVVBJKI-ACOLCOCVSA-N","160706","C[C@]12CCC(=O)C=C1CCC3C2[C@H]4CC5(C3CC[C@@H]5C(=O)CO)C(O4)O[C@H]6[C@@H]([C@H]([C@@H]([C@H](O6)C(=O)O)O)O)O",0.0023,2.2,"160706",16,-0.318,"cholic acids","",0.23]
["Isobutyryl-L-carnitine","LRCNOZRCYBNMEP-SECBINFHSA-N","168379","CC(C)C(=O)OC(CC(=O)[O-])C[N+](C)(C)C",0.00082,2.2,"168379",20,-0.455,"carnitine","h",0.095]
["L-Homocysteic acid","VBOQYPQEPHKASR-VKHMYHEASA-N","177491","C(CS(=O)(=O)O)[C@@H](C(=O)O)N",0.0016,3.1,"177491",10,-4.001,"methionine","",0.17]
["7-Ketodeoxycholic acid","RHCPKKNRWFXMAT-RRWYKFPJSA-N","188292","C[C@H](CCC(=O)O)[C@H]1CC[C@@H]2[C@@]1([C@H](C[C@H]3[C@H]2C(=O)C[C@H]4[C@@]3(CC[C@H](C4)O)C)O)C",0.0066,1.8,"188292",6,3.68,"cholic acids","f",0.57]
["Cholic acid","BHQCQFFYRZLCQQ-OELDTZBJSA-N","221493","C[C@H](CCC(=O)O)[C@H]1CC[C@@H]2[C@@]1([C@H](C[C@H]3[C@H]2[C@@H](C[C@H]4[C@@]3(CC[C@H](C4)O)C)O)O)C",0.047,2.4,"221493",4,4.093,"cholic acids","",0.97]
["Deoxycholic acid","KXGVEGMKQFWNSR-LLQZFEROSA-N","222528","C[C@H](CCC(=O)O)[C@H]1CC[C@@H]2[C@@]1([C@H](C[C@H]3[C@H]2CC[C@H]4[C@@]3(CC[C@H](C4)O)C)O)C",0.042,2.1,"222528",14,5.756,"cholic acids","",0.97]
["L-Pipecolic acid","HXEACLLIILLPRG-YFKPBYRVSA-N","439227","C1CCN[C@@H](C1)C(=O)O",0.0092,2,"439227",9,0.173,"pipecolic acids","",0.72]
["3a,7a,12a-Trihydroxy-5b-cholestan-26-al","USFJGINJGUIFSY-XZULNKEGSA-N","439479","C[C@H](CCCC(C)C=O)[C@H]1CC[C@@H]2[C@@]1([C@H](C[C@H]3[C@H]2[C@@H](C[C@H]4[C@@]3(CC[C@H](C4)O)C)O)O)C",0.023,0.51,"439479",17,5.938,"cholestanols","",0.97]
["D-Urobilinogen","KSQFFJKKJAEKTB-UHFFFAOYSA-N","440784","CCC1=C(C(=O)NC1CC2=C(C(=C(N2)CC3=C(C(=C(N3)CC4C(=C(C(=O)N4)C=C)C)C)CCC(=O)O)CCC(=O)O)C)C",0.00056,0.26,"440784",31,1.318,"bile pigments","",0.067]
["trans-Cinnamic acid","WBYWAXJHAXSJNI-VOTSOKGWSA-N","444539","C1=CC=C(C=C1)/C=C/C(=O)O",6.8e-05,2.8,"444539",27,1.887,"cinnamates","i",0.0092]
["Oleic acid","ZQPPMHVWECSIRJ-KTKRTIGZSA-N","445639","CCCCCCCC/C=C\\CCCCCCCC(=O)O",0.0013,0.57,"445639",1,8.192,"UnSaturated FA","j",0.14]
["trans-Ferulic acid","KSEBMYQBYZTDHS-HWKANZROSA-N","445858","COC1=C(C=CC(=C1)/C=C/C(=O)O)O",0.00032,0.46,"445858",22,0.512,"cinnamates","",0.04]
["Riboflavin","AUNGANRZJHBGPY-SCRDCRAPSA-N","493570","CC1=CC2=C(C=C1C)N(C3=NC(=O)NC(=O)C3=N2)C[C@@H]([C@@H]([C@@H](CO)O)O)O",0.0015,1.8,"493570",5,-2.049,"flavins","",0.16]
["Ricinoleic acid","WBHHMMIMDMUBKC-QJWNTBNXSA-N","643684","CCCCCCC(C/C=C\\CCCCCCCC(=O)O)O",0.00022,4.2,"643684",7,6.107,"DiHOME","",0.029]
["N-Decanoylglycine","WRRYZYASRAUROW-UHFFFAOYSA-N","1712391","CCCCCCCCCC(=O)NCC(=O)O",0.025,0.5,"1712391",13,3.328,"stearic acids","d",0.97]
["MG(16:0/0:0/0:0)","QHZLMUACJMDIAE-SFHVURJKSA-N","3084463","CCCCCCCCCCCCCCCC(=O)OC[C@H](CO)O",0.026,0.62,"3084463",37,6.51,"glycerides","",0.97]
["L-Hexanoylcarnitine","VVPRQWTYSNDTEA-LLVKDONJSA-N","3246938","CCCCCC(=O)O[C@H](CC(=O)[O-])C[N+](C)(C)C",0.034,1.6,"3246938",35,0.959,"carnitine","",0.97]
["Linoleic acid","OYHQOLUKZRVURQ-HZJYTTRNSA-N","5280450","CCCCC/C=C\\C/C=C\\CCCCCCCC(=O)O",0.00033,4.8,"5280450",1,7.865,"UnSaturated FA","j",0.041]
["L-Urobilin","TYOWQSLRVAUSMI-WKULSOCRSA-N","5280818","CCC1C(C(=O)NC1CC2=N/C(=C/C3=C(C(=C(N3)CC4C(C(C(=O)N4)CC)C)C)CCC(=O)O)/C(=C2C)CCC(=O)O)C",0.0022,0.43,"5280818",18,1.922,"bile pigments","k",0.22]
["Gamma-Linolenic acid","VZCCETWTMQHEPK-QNEBEIHSSA-N","5280933","CCCCC/C=C\\C/C=C\\C/C=C\\CCCCC(=O)O",0.00047,0.6,"5280933",1,7.538,"UnSaturated FA","j",0.057]
["Alpha-Linolenic acid","DTOSIQBPPRVQHS-PDBXOOCHSA-N","5280934","CC/C=C\\C/C=C\\C/C=C\\CCCCCCCC(=O)O",0.0074,0.34,"5280934",1,7.538,"UnSaturated FA","j",0.63]
["trans-Piceid","HSTZMXCBWJGKHG-CUYWLFDKSA-N","5281718","C1=CC(=CC=C1/C=C/C2=CC(=CC(=C2)O[C@H]3[C@@H]([C@H]([C@@H]([C@H](O3)CO)O)O)O)O)O",0.037,0.34,"5281718",22,0.742,"stilbenes","",0.97]
["Linoelaidic acid","OYHQOLUKZRVURQ-AVQMFFATSA-N","5282457","CCCCC/C=C/C/C=C/CCCCCCCC(=O)O",0.016,0.69,"5282457",1,7.865,"UnSaturated FA","j",0.88]
["3-Oxohexadecanoic acid","ASICPMTWQSESKX-UHFFFAOYSA-N","5282997","CCCCCCCCCCCCCC(=O)CC(=O)O",0.0052,0.42,"5282997",12,6.478,"O=FA_16_1","",0.48]
["Oleamide","FATBGEAMYMYZAF-KTKRTIGZSA-N","5283387","CCCCCCCC/C=C\\CCCCCCCC(=O)N",0.00047,1.8,"5283387",13,7.464,"oleic acids","d",0.057]
["Alpha-Linolenoyl ethanolamide","HBJXRRXWHSHZPU-PDBXOOCHSA-N","5283449","CC/C=C\\C/C=C\\C/C=C\\CCCCCCCC(=O)NCCO",0.013,0.6,"5283449",13,6.619,"polyunsaturated alkamides","d",0.82]
["3b,12a-Dihydroxy-5a-cholanoic acid","KXGVEGMKQFWNSR-UPSXFCICSA-N","5283835","C[C@H](CCC(=O)O)[C@H]1CC[C@@H]2[C@@]1([C@H](C[C@H]3[C@H]2CC[C@@H]4[C@@]3(CC[C@@H](C4)O)C)O)C",0.0096,7.2,"5283835",14,5.756,"cholic acids","",0.73]
["3a,7a,12b-Trihydroxy-5b-cholanoic acid","BHQCQFFYRZLCQQ-KRHHAYMPSA-N","5283869","C[C@H](CCC(=O)O)[C@H]1CC[C@@H]2[C@@]1([C@@H](C[C@H]3[C@H]2[C@@H](C[C@H]4[C@@]3(CC[C@H](C4)O)C)O)O)C",0.016,1.9,"5283869",4,4.093,"cholic acids","",0.88]
["3-Oxo-4,6-choladienoic acid","CREVIXFSUWYGRJ-IHMUCKAYSA-N","5283992","C[C@H](CCC(=O)O)[C@H]1CC[C@@H]2[C@@]1(CC[C@H]3[C@H]2C=CC4=CC(=O)CC[C@]34C)C",0.013,1.8,"5283992",23,6.873,"cholic acids","e",0.82]
["(Z)-13-Hexadecenoic acid","UFRASUJYZLLIJC-ARJAWSKDSA-N","5312416","CC/C=C\\CCCCCCCCCCCC(=O)O",0.031,0.54,"5312416",1,7.054,"UnSaturated FA","j",0.97]
["Palmitoleic acid","RVEKLXYYCHAMDF-UTOQUPLUSA-N","5312427","CCCCCC/C=C\\CCCCCCCC(=O)O",0.032,0.19,"5312427",1,7.054,"UnSaturated FA","j",0.97]
["10Z-Heptadecenoic acid","GDTXICBNEOEPAZ-FPLPWBNLSA-N","5312435","CCCCCC\\C=C/CCCCCCCCC(O)=O",0.0012,0.11,"5312435",1,7.623,"UnSaturated FA","j",0.14]
["(Z)-9-Heptadecenoic acid","QSBYPNXLFMSGKH-CMDGGOBGSA-N","5312440","CCCCCCC/C=C/CCCCCCCC(=O)O",0.00063,0.0046,"5312440",1,7.623,"UnSaturated FA","j",0.074]
["MG(0:0/18:1(9Z)/0:0)","UPWGQKDVAURUGE-KTKRTIGZSA-N","5319879","CCCCCCCC/C=C\\CCCCCCCC(=O)OC(CO)CO",0.0011,0.32,"5319879",2,7.132,"glycerides","",0.13]
["Cinnamic acid","WBYWAXJHAXSJNI-SREVYHEPSA-N","5372954","C1=CC=C(C=C1)/C=C\\C(=O)O",0.037,1.8,"5372954",27,1.887,"cinnamates","i",0.97]
["Docosapentaenoic acid","YUFFSWGQGVEMMI-JLNKQSITSA-N","5497182","CC/C=C\\C/C=C\\C/C=C\\C/C=C\\C/C=C\\CCCCCC(=O)O",0.0015,2.3,"5497182",1,9.16000000000001,"UnSaturated FA","j",0.16]
["I-Urobilin","KDCCOOGTVSRCHX-MBTHVWNTSA-N","5795125","CCC1=C(C(=O)NC1CC2=C(C(=C(N2)/C=C\\3/C(=C(C(=N3)CC4C(=C(C(=O)N4)CC)C)C)CCC(=O)O)CCC(=O)O)C)C",0.00011,0.35,"5795125",18,0.906,"bile pigments","k",0.015]
["D-Urobilin","DOKCNDVEPDZOJQ-MBTHVWNTSA-N","6276321","CCC1=C(C(=O)NC1CC2=C(C(=C(N2)/C=C\\3/C(=C(C(=N3)CC4C(=C(C(=O)N4)C=C)C)C)CCC(=O)O)CCC(=O)O)C)C",0.0019,0.39,"6276321",18,0.905,"bile pigments","k",0.19]
["MG(18:2(9Z,12Z)/0:0/0:0)","WECGLUPZRHILCT-GSNKCQISSA-N","6436630","CCCCC/C=C\\C/C=C\\CCCCCCCC(=O)OC[C@H](CO)O",0.00016,0.29,"6436630",2,6.805,"glycerides","",0.021]
["Leukotriene E3","KRTWHKZMWCZCIK-VRZYSOTLSA-N","6440643","CCCCCCCC/C=C\\C=C\\C=C\\[C@H]([C@H](CCCC(=O)O)O)SC[C@@H](C(=O)O)N",0.016,2.5,"6440643",8,3.383,"srs-a","",0.88]
["13-OxoODE","JHXAZBBVQSRKJR-BSZOFBHHSA-N","6446027","CCCCCC(=O)/C=C/C=C\\CCCCCCCC(=O)O",0.0081,0.34,"6446027",1,5.656,"UnSaturated FA","j",0.66]
["LysoPE(14:0/0:0)","RPXHXZNGZBHSMJ-GOSISDBHSA-N","9547070","CCCCCCCCCCCCCC(=O)OC[C@H](COP(=O)(O)OCCN)O",0.04,0.61,"9547070",30,3.886,"lysophospholipids","l",0.97]
["3b,17a-Dihydroxy-5a-androstane","CBMYJHIOYJEBSB-ILNNWSBUSA-N","9835719","C[C@]12CCC3C(C1CC[C@H]2O)CCC4[C@@]3(CC[C@@H](C4)O)C",0.0012,0.39,"9835719",15,4.907,"androstanols","",0.14]
["9,10-DHOME","XEBKSQSGNGRGDW-YFHOEESVSA-N","9966640","CCCCC/C=C\\CC(C(CCCCCCCC(=O)O)O)O",0.037,0.41,"9966640",7,4.866,"DiHOME","",0.97]
["12,13-DHOME","CQSLTKIXAJTQGA-FLIBITNWSA-N","10236635","CCCCCC(C(C/C=C\\CCCCCCCC(=O)O)O)O",0.026,0.19,"10236635",7,4.866,"DiHOME","",0.97]
["(S)-9-Hydroxy-10-undecenoic acid","CJUFNYIRKDOQMC-UHFFFAOYSA-N","10465398","C=CC(CCCCCCCC(=O)O)O",0.0018,0.33,"10465398",7,2.54,"DiHOME","",0.19]
["LysoPC(18:2(9Z,12Z))","SPJFYYJXNPEZDW-FTJOPAKQSA-N","11005824","CCCCC/C=C\\C/C=C\\CCCCCCCC(=O)OC[C@H](COP(=O)([O-])OCC[N+](C)(C)C)O",0.0096,290,"11005824",28,5.757,"lysophospholipids","m",0.73]
["MG(0:0/18:3(6Z,9Z,12Z)/0:0)","BXAXVVVVPFELOK-QNEBEIHSSA-N","11646044","CCCCC/C=C\\C/C=C\\C/C=C\\CCCCC(=O)OC(CO)CO",0.0048,0.39,"11646044",2,6.478,"diglycerides","",0.45]
["MG(0:0/18:3(9Z,12Z,15Z)/0:0)","ZCCLDKGWJIREQF-PDBXOOCHSA-N","11674746","CC/C=C\\C/C=C\\C/C=C\\CCCCCCCC(=O)OC(CO)CO",0.0035,0.35,"11674746",2,6.478,"diglycerides","",0.34]
["MG(18:1(9Z)/0:0/0:0)","RZRNAYUHWVFMIP-QJRAZLAKSA-N","12178130","CCCCCCCC/C=C\\CCCCCCCC(=O)OC[C@H](CO)O",0.032,0.73,"12178130",2,7.132,"glycerides","",0.97]
["Indoleacrylic acid","SXOUIMVOMIGLHO-AATRIKPKSA-N","15030923","C1=CC=C2C(=C1)C=C(N2)/C=C/C(=O)O",0.0099,1.8,"15030923",5,1.323,"indoles","",0.73]
["3-Hydroxytetradecanedioic acid","CEDZIURHISELSQ-UHFFFAOYSA-N","20848956","C(CCCCCC(=O)O)CCCCC(CC(=O)O)O",0.043,1.8,"20848956",12,3.106,"O=FA_14_1","",0.97]
["Cholic acid glucuronide","RBLDVEUUCHVWMW-SXYQVCRBSA-N","21252309","C[C@H](CCC(=O)O)[C@H]1CC[C@@H]2[C@@]1([C@H](C[C@H]3[C@H]2[C@@H](C[C@H]4[C@@]3(CC[C@H](C4)O[C@H]5[C@@H]([C@H]([C@@H]([C@H](O5)C(=O)O)O)O)O)C)O)O)C",0.0028,0.38,"21252309",16,3.142,"cholic acids","",0.27]
["4a-Methylzymosterol","FOUJWBXBKVVHCJ-YIJYGBTNSA-N","22212495","C[C@H]1[C@@H]2CCC3=C([C@]2(CC[C@@H]1O)C)CC[C@]4([C@H]3CC[C@@H]4[C@H](C)CCC=C(C)C)C",0.043,0.36,"22212495",34,9.403,"cholestadienols","",0.97]
["Glutarylglycine","NBLKTRLPZFCMJG-UHFFFAOYSA-N","23592950","C(CC(=O)NCC(=O)O)CC(=O)O",0.048,1.7,"23592950",9,-1.18,"","",0.97]
["2-Oleoylglycerophosphocholine","SULIDBRAXVDKBU-PTGWMXDISA-N","24779494","[H][C@@](CO)(COP([O-])(=O)OCC[N+](C)(C)C)OC(=O)CCCCCCC\\C=C/CCCCCCCC",0.015,0.36,"24779494",28,6.084,"lysophospholipids","m",0.87]
["4Alpha-hydroxymethyl-5alpha-cholesta-8-en-3beta-ol","UPEGTKGKNWDIAN-GYISYUOESA-N","25201885","CC(C)CCCC(C)C1CCC2[C@@]1(CCC3=C2CCC4[C@@]3(CC[C@@H]([C@H]4CO)O)C)C",0.034,0.34,"25201885",34,9.557,"cholesterol","",0.97]
["LysoPE(18:2(9Z,12Z)/0:0)","DBHKHNGBVGWQJE-USWSLJGRSA-N","52925130","CCCCC/C=C\\C/C=C\\CCCCCCCC(=O)OC[C@H](COP(=O)(O)OCCN)O",0.024,0.27,"52925130",8,5.319,"plasmalogens","",0.97]
["PS(22:6(4Z,7Z,10Z,13Z,16Z,19Z)/18:0)","YZPDRIODLGOXPQ-VQXQEPRVSA-N","52925937","CCCCCCCCCCCCCCCCCC(=O)O[C@H](COC(=O)CC/C=C\\C/C=C\\C/C=C\\C/C=C\\C/C=C\\C/C=C\\CC)COP(=O)(O)OC[C@@H](C(=O)O)N",0.0073,3.3,"52925937",8,13.134,"glycerophospholipids","",0.63]
["2b,3a,7a,12a-Tetrahydroxy-5b-cholanoic acid","IMMADCCLTPCOKH-DLPNMVJGSA-N","53477680","C[C@@H](CCC(=O)O)C1CCC2[C@@]1([C@H](CC3C2[C@@H](C[C@H]4[C@@]3(C[C@@H]([C@H](C4)O)O)C)O)O)C",0.018,1.5,"53477680",19,3.281,"cholic acids","",0.94]
["1b,3a,12a-Trihydroxy-5b-cholanoic acid","DAKYVYUAVGJDRK-LFMRMFNLSA-N","53477683","C[C@H](CCC(=O)O)C1CCC2[C@@]1([C@H](CC3C2CCC4[C@@]3([C@@H](C[C@H](C4)O)O)C)O)C",0.0096,2.7,"53477683",4,4.304,"cholic acids","",0.73]
["3a,4b,12a-Trihydroxy-5b-cholanoic acid","FRYVQXCDSBCDAU-IQXKVUNVSA-N","53477684","C[C@@H](CCC(=O)O)C1CCC2[C@@]1([C@H](CC3C2CCC4[C@@]3(CC[C@H]([C@@H]4O)O)C)O)C",0.0076,2.2,"53477684",19,4.733,"cholic acids","",0.63]
["3a,7a-Dihydroxycoprostanic acid","ITZYGDKGRKKBSN-KLYSAGIUSA-N","53477686","C[C@H](CCCC(C)C(=O)O)[C@H]1CC[C@@H]2[C@@]1(CC[C@H]3C2[C@@H](C[C@H]4[C@@]3(CC[C@H](C4)O)C)O)C",0.015,0.54,"53477686",4,7.609,"cholic acids","",0.87]
["3b,17b-Dihydroxyetiocholane","CBMYJHIOYJEBSB-WTVXNACZSA-N","53477687","C[C@]12CCC3C(C1CC[C@@H]2O)CCC4[C@@]3(CC[C@@H](C4)O)C",0.014,0.47,"53477687",15,4.907,"androstanols","",0.83]
["12a-Hydroxy-3-oxocholadienic acid","DJVAMCYXFUWMLS-RVOJYKBWSA-N","53477691","C[C@H](CCC(=O)O)C1CCC2[C@@]1([C@H](CC3C2C=CC4=CC(=O)CC[C@]34C)O)C",0.004,3.1,"53477691",23,4.366,"cholic acids","e",0.38]
["Nutriacholic acid","DXOCDBGWDZAYRQ-QPVZPPSOSA-N","53477693","C[C@@H](CCC(=O)O)C1CC[C@@H]2[C@@]1(CC[C@H]3[C@H]2C(=O)C[C@H]4[C@@]3(CC[C@H](C4)O)C)C",0.046,1.6,"53477693",6,5.765,"deoxycholic acid","f",0.97]
["3-Oxocholic acid","OEKUSRBIIZNLHZ-ZHDFXGGTSA-N","53477697","C[C@H](CCC(=O)O)[C@@H]1CC[C@@H]2[C@@]1([C@@H](C[C@H]3[C@H]2[C@@H](C[C@H]4[C@@]3(CCC(=O)C4)C)O)O)C",0.0017,2.2,"53477697",6,3.684,"cholic acids","f",0.18]
["7a-Hydroxy-3-oxo-5b-cholanoic acid","KNVADAPHVNKTEP-KXIRRPOASA-N","53477698","C[C@H](CCC(=O)O)C1CC[C@@H]2[C@@]1(CC[C@H]3[C@H]2[C@@H](C[C@H]4[C@@]3(CCC(=O)C4)C)O)C",0.011,1.6,"53477698",6,5.769,"cholic acids","f",0.78]
["Allocholic acid","BHQCQFFYRZLCQQ-HXCSUAOSSA-N","53477699","C[C@H](CCC(=O)O)[C@H]1CC[C@@H]2[C@@]1(C(C[C@H]3[C@H]2[C@@H](C[C@@H]4[C@@]3(CC[C@H](C4)O)C)O)O)C",0.044,1.9,"53477699",4,4.093,"cholic acids","",0.97]
["5a-Cholestane-3a,7a,12a,25-tetrol","NTIXPPFPXLYJCT-SUGKMTRFSA-N","53477702","C[C@H](CCCC(C)(C)O)C1CC[C@@H]2[C@@]1([C@H](C[C@H]3[C@H]2[C@@H](C[C@@H]4[C@@]3(CC[C@H](C4)O)C)O)O)C",3.1e-05,0.31,"53477702",15,5.648,"cholestanols","",0.0042]
["Deoxycholic acid 3-glucuronide","NNEIBJNHWVDJBA-WJQHFXMBSA-N","53477755","C[C@H](CCC(=O)O)C1CC[C@@H]2[C@@]1([C@H](C[C@H]3[C@H]2CC[C@H]4[C@@]3(CC[C@H](C4)OC5[C@@H]([C@H]([C@@H]([C@H](O5)C(=O)O)O)O)O)C)O)C",0.00023,0.41,"53477755",16,4.805,"cholic acids","",0.03]
["Tetradecanoylcarnitine","PSHXNVGSVNEJBD-LJQANCHMSA-N","53477791","CCCCCCCCCCCCCC(=O)O[C@H](CC(=O)[O-])C[N+](C)(C)C",0.0003,0.29,"53477791",35,5.511,"carnitine","",0.038]
["7a,12a-Dihydroxy-5a-cholestan-3-one","HHVQPBXBALLUDF-PUOAGSAWSA-N","53477902","CC(C)CCCC(C)C1CC[C@@H]2[C@@]1(C(C[C@H]3C2[C@@H](CC4[C@@]3(CCC(=O)C4)C)O)O)C",0.0013,0.44,"53477902",17,7.204,"cholic acids","",0.14]
["7a,12a-Dihydroxy-5b-cholestan-3-one","HHVQPBXBALLUDF-VYSDRBBMSA-N","53477903","CC(C)CCCC(C)C1CC[C@H]2[C@@]1(C(C[C@H]3C2[C@@H](CC4[C@@]3(CCC(=O)C4)C)O)O)C",0.01,0.51,"53477903",17,7.204,"cholic acids","",0.73]
["PC(20:4(8Z,11Z,14Z,17Z)/20:2(11Z,14Z))","ZKUNPSXZRWGSCW-FLRYMGIISA-N","53479085","CCCCC/C=C\\C/C=C\\CCCCCCCCCC(=O)O[C@H](COC(=O)CCCCCC/C=C\\C/C=C\\C/C=C\\C/C=C\\CC)COP(=O)([O-])OCC[N+](C)(C)C",0.0074,2.5,"53479085",29,16.064,"glycerophospholipids","",0.63]
["9-HOTE","YUPHIKSLGBATJK-OBKPXJAFSA-N","53480359","CC/C=C\\CC/C=C/C=C(\\CCCCCCCC(=O)O)/O",0.038,0.55,"53480359",1,5.763,"UnSaturated FA","j",0.97]
["LysoPE(0:0/14:0)","DDUZNLUWXLYPCP-GOSISDBHSA-N","53480919","CCCCCCCCCCCCCC(=O)O[C@H](CO)COP(=O)(O)OCCN",0.012,0.53,"53480919",30,3.886,"lysophospholipids","l",0.82]
["LysoPE(0:0/18:2(9Z,12Z))","SVRBKLJIDJHADS-USWSLJGRSA-N","53480926","CCCCC/C=C\\C/C=C\\CCCCCCCC(=O)O[C@H](CO)COP(=O)(O)OCCN",0.018,0.3,"53480926",8,5.319,"plasmalogens","",0.94]
["LysoPE(0:0/20:3(11Z,14Z,17Z))","OQKGGFIWKFEWBV-WCABUCBOSA-N","53480933","CC/C=C\\C/C=C\\C/C=C\\CCCCCCCCCC(=O)O[C@H](CO)COP(=O)(O)OCCN",0.0092,0.26,"53480933",8,6.13,"plasmalogens","",0.72]
["LysoPE(0:0/20:3(5Z,8Z,11Z))","FJDVENKXPUIXRG-WMTBOZPISA-N","53480934","CCCCCCCC/C=C\\C/C=C\\C/C=C\\CCCC(=O)O[C@H](CO)COP(=O)(O)OCCN",0.033,0.24,"53480934",32,6.13000000000001,"plasmalogens","",0.97]
["LysoPE(0:0/20:4(5Z,8Z,11Z,14Z))","YWOCITMXHHTBAW-XSQXPFHXSA-N","53480936","CCCCC/C=C\\C/C=C\\C/C=C\\C/C=C\\CCCC(=O)O[C@H](CO)COP(=O)(O)OCCN",0.0025,0.21,"53480936",32,5.80300000000001,"plasmalogens","",0.25]
["MG(16:1(9Z)/0:0/0:0)","KVYUBFKSKZWZSV-ZEVQVBBLSA-N","53480976","CCCCCC/C=C\\CCCCCCCC(=O)OC[C@H](CO)O",0.026,0.17,"53480976",2,5.994,"diglycerides","",0.97]
["MG(18:3(9Z,12Z,15Z)/0:0/0:0)","GGJRAQULURVTAJ-IWFQAGGASA-N","53480979","CC/C=C\\C/C=C\\C/C=C\\CCCCCCCC(=O)OC[C@H](CO)O",0.0013,0.1,"53480979",2,6.478,"diglycerides","",0.14]
["MG(22:6(4Z,7Z,10Z,13Z,16Z,19Z)/0:0/0:0)","JWPHORDRFVRZPP-PJEZTNATSA-N","53480995","CC/C=C\\C/C=C\\C/C=C\\C/C=C\\C/C=C\\C/C=C\\CCC(=O)OC[C@H](CO)O",0.023,0.35,"53480995",2,7.773,"diglycerides","",0.97]
["Hydroxyvalerylcarnitine","PSRQDLCMEPQOQH-YZRBJQDESA-N","53481626","CCC(CC(O)O[C@@H](CC(=O)[O-])C[N+](C)(C)C)O",0.024,1.9,"53481626",20,-1.29,"carnitine","h",0.97]
["PC(o-18:1(9Z)/18:0)","KKPRQPUSFKIYMO-GRVDSVFJSA-N","53481723","CCCCCCCCCCCCCCCCCC(=O)O[C@H](COCCCCCCCC/C=C\\CCCCCCCC)COP(=O)([O-])OCC[N+](C)(C)C",0.02,1.8,"53481723",29,15.919,"glycerophospholipids","",0.94]
["Ascorbic acid","CIWBSHSKHKDKBQ-JLAZNSOCSA-N","54670067","C([C@@H]([C@@H]1C(=C(C(=O)O1)O)O)O)O",0.031,0.53,"54670067",39,-0.178,"sugar acids","g",0.97]
["Hyocholic acid","DKPMWHFRUGMUKF-NNFRHCBVSA-N","131750324","[H][C@@]12CCC([C@H](C)CCC(O)=O)[C@@]1(C)CC[C@@]1([H])[C@@]2([H])[C@H](O)[C@H](O)[C@]2([H])C[C@H](O)CC[C@]12C",0.032,27,"131750324",19,5.366,"cholic acids","",0.97]
["12,13-Epoxy-9,15-octadecadienoic acid","BKKGUKSHPCTUGE-GSRSKSEFSA-N","131751130","CC\\C=C/CC1OC1C\\C=C\\CCCCCCCC(O)=O",0.0012,0.39,"131751130",7,5.368,"DiHOME","",0.14]
["P-values are the result of the Kolmogorov-Smirnov test evaluating how significant difference a metabolite cluster was represented by chance. FDR is the Benjamini-Hochberg corrected p values. The Increase/ratio (Decreased/ratio) shows the numbers/ratio of directions of significant compounds in a cluster."]

{"sheet":"Table S4","index":3,"n_rows":15,"n_cols":7,"rows_kept":15,"cut":false,"hidden":false,"merged":[],"flags":["formulas_cached_only"]}
["Table S4. Disordered metabolic pathways caused by CTX induction."]
[null,"Total Cmpd","Hits","Raw p","Holm adjust","FDR","Impact"]
["Linoleic acid metabolism",5,2,0.000555,0.021317,0.004363,1]
["alpha-Linolenic acid metabolism",13,2,0.002024,0.07083,0.009282,0.33333]
["Alanine, aspartate and glutamate metabolism",28,5,0.000547,0.021317,0.004363,0.3109]
["Pentose and glucuronate interconversions",18,2,0.000102,0.004182,0.002142,0.26562]
["Arginine and proline metabolism",38,4,0.002598,0.08573,0.009282,0.25449]
["Ascorbate and aldarate metabolism",10,1,0.000727,0.026905,0.004363,0.25]
["Pyruvate metabolism",22,1,0.002873,0.091937,0.009282,0.20684]
["Tyrosine metabolism",42,2,0.008625,0.22425,0.021309,0.13972]
["Glycerophospholipid metabolism",36,2,0.008139,0.21976,0.021309,0.11182]
["Pyrimidine metabolism",39,3,0.012192,0.30404,0.02668,0.10507]
["Cysteine and methionine metabolism",33,2,0.004754,0.13787,0.014262,0.10446]
["Glycolysis / Gluconeogenesis",26,1,0.002873,0.091937,0.009282,0.10044]
["Total is referring to the number of metabolites in each pathway, where Hits is the number of matched metabolites in each pathway. Raw P, Holm P and FDR are the P values of original calculated, adjusted by Holm method and adjusted by false discovery level, respectively. Impact is the calculated value of influence of each pathway."]

{"sheet":"Table S5","index":4,"n_rows":139,"n_cols":59,"rows_kept":139,"cut":false,"hidden":false,"merged":[[0,0,0,5],[1,0,1,4],[1,6,1,10],[1,12,1,16],[1,18,1,22],[1,24,1,28],[1,30,1,34],[1,36,1,40],[1,42,1,46],[1,48,1,52],[1,54,1,58]],"flags":["formulas_cached_only"]}
["Table S5. Significantly different metabolites of MG compared to each group. (p < 0.05, VIP > 1 in the OPLS-DA)."]
["MG/NG",{"$nulls":5},"MG/Xanthan gum",{"$nulls":5},"MG/Inulin",{"$nulls":5},"MG/Guar gum",{"$nulls":5},"MG/Arabinogalactan",{"$nulls":5},"MG/Carrageenan",{"$nulls":5},"MG/Glucomannan",{"$nulls":5},"MG/Araboxylan",{"$nulls":5},"MG/Xylan",{"$nulls":5},"MG/Fucoidan"]
["Metabolites name","HMDB ID","Cluster by HMDB","Fold Change","p.value",null,"Metabolites name","HMDB ID","Cluster by HMDB","p.value","Fold Change",null,"Metabolites name","HMDB ID","Cluster by HMDB","p.value","Fold Change",null,"Metabolites name","HMDB ID","Cluster by HMDB","p.value","Fold Change",null,"Metabolites name","HMDB ID","Cluster by HMDB","p.value","Fold Change",null,"Metabolites name","HMDB ID","Cluster by HMDB","p.value","Fold Change",null,"Metabolites name","HMDB ID","Cluster by HMDB","p.value","Fold Change",null,"Metabolites name","HMDB ID","Cluster by HMDB","p.value","Fold Change",null,"Metabolites name","HMDB ID","Cluster by HMDB","p.value","Fold Change",null,"Metabolites name","HMDB ID","Cluster by HMDB","p.value","Fold Change"]
["Ascorbic acid","HMDB0000044","Furanones",0.52939,0.030998,null,"alpha-Tocopherol acetate","HMDB0034227","Vitamin E compounds",0.023046,2.1833,null,"Oleoylcarnitine","HMDB0005065","Acyl carnitines",0.0077771,1.8969,null,"LysoPC(18:4(6Z,9Z,12Z,15Z)/0:0)","HMDB0010389","Lysophosphatidylcholines",0.028377,0.53584,null,"PE(14:0/18:3(6Z,9Z,12Z))","HMDB0008830","Glycerophospholipids",0.024174,3.1774,null,"PE(18:3(6Z,9Z,12Z)/20:2(11Z,14Z))","HMDB0009132","Glycerophospholipids",0.0073249,0.19921,null,"Adenosine","HMDB0000050","Purine nucleosides",0.036428,1.526,null,"Adenosine","HMDB0000050","Purine nucleosides",0.019285,1.7016,null,"Adenosine","HMDB0000050","Purine nucleosides",0.0020676,2.0206,null,"Adenosine","HMDB0000050","Purine nucleosides",0.034386,1.539]
["Adenosine","HMDB0000050","Purine nucleosides",1.5758,0.036554,null,"PS(14:0/16:0)","HMDB0012332","Glycerophospholipids",0.018425,0.37415,null,"Tetradecanoylcarnitine","HMDB0005066","Acyl carnitines",0.0023326,0.41657,null,"D-Urobilin","HMDB0004161","Bilirubins",0.015454,0.47734,null,"Adenosine","HMDB0000050","Purine nucleosides",0.028761,1.6269,null,"Riboflavin (Vitamin B2)","HMDB0000244","Alloxazines and isoalloxazines ",0.0079572,1.7173,null,"5a-Cholestane-3a,7a,12a,25-tetrol","HMDB0000520","Glycerophospholipids",0.018321,1.6359,null,"LysoPE(0:0/20:3(11Z,14Z,17Z))","HMDB0011484","Glycerophosphoethanolamines",0.048481,1.5702,null,"Cholic acid glucuronide","HMDB0002577","Estrane steroids ",0.046334,0.56544,null,"Riboflavin (Vitamin B2)","HMDB0000244","Alloxazines and isoalloxazines ",0.0021526,1.7632]
["D-Glucuronic acid","HMDB0000127","Carbohydrates and carbohydrate conjugates",0.18207,0.00058548,null,"PE(14:0/18:3(6Z,9Z,12Z))","HMDB0008830","Glycerophospholipids",0.042578,2.7866,null,"hydroxyisovaleroyl carnitine","HMDB0062555","Acyl carnitines ",0.036859,0.3337,null,"Urobilinogen","HMDB0004158","Bilirubins",0.0033028,0.39726,null,"5a-Cholestane-3a,7a,12a,25-tetrol","HMDB0000520","Glycerophospholipids",0.044296,1.4476,null,"PE(20:5(5Z,8Z,11Z,14Z,17Z)/P-16:0)","HMDB0009477","Glycerophospholipids",0.026628,0.26328,null,"PE(18:3(6Z,9Z,12Z)/20:2(11Z,14Z))","HMDB0009132","Glycerophospholipids",0.021201,0.12446,null,"Urobilinogen","HMDB0004158","Bilirubins",0.010558,0.40465,null,"Urobilinogen","HMDB0004158","Bilirubins",0.0010775,0.2766,null,"PC(15:0/22:5(4Z,7Z,10Z,13Z,16Z))","HMDB0007956","Glycerophospholipids",0.0035279,21.718]
["L-Glutamic acid","HMDB0000148","Amino acids, peptides, and analogues",1.4686,0.015349,null,"Cholic acid glucuronide","HMDB0002577","Estrane steroids ",0.00093649,0.47678,null,"Heptadecanoyl carnitine","HMDB0006210","Acyl carnitines ",0.029746,0.2665,null,"Hyocholic acid","HMDB0000760","Bile acids, alcohols and derivatives",0.02271,31.515,null,"(R)-Lipoic acid","HMDB0001451","Lipoic acids and derivatives",0.0067789,2.4689,null,"PC(15:0/22:5(4Z,7Z,10Z,13Z,16Z))","HMDB0007956","Glycerophospholipids",0.0027819,27.974,null,"PE(14:1(9Z)/14:0)","HMDB0008854","Glycerophospholipids",0.013527,0.34907,null,"12a-Hydroxy-3-oxocholadienic acid","HMDB0000385","Bile acids, alcohols and derivatives",0.028612,1.9943,null,"(R)-Lipoic acid","HMDB0001451","Lipoic acids and derivatives",0.040793,1.9514,null,"Urobilinogen","HMDB0004158","Bilirubins",0.02,0.4814]
["L-Tyrosine","HMDB0000158","Amino acids, peptides, and analogues",3.7311,0.04576,null,"(R)-Lipoic acid","HMDB0001451","Lipoic acids and derivatives",0.013513,2.4154,null,"9-Hexadecenoylcarnitine","HMDB0013207","Acyl carnitines ",0.048255,3.2812,null,"MG(18:3(6Z,9Z,12Z)/0:0/0:0)","HMDB0011569","Lineolic acids and derivatives",0.011,0.22134,null,"L-Carnitine","HMDB0000062","Carnitines",0.049819,1.751,null,"Urobilinogen","HMDB0004158","Bilirubins",0.02847,0.32574,null,"Hyocholic acid","HMDB0000760","Bile acids, alcohols and derivatives",0.0097113,3.2895,null,"(R)-Lipoic acid","HMDB0001451","Lipoic acids and derivatives",0.015182,2.2661,null,"Stearidonic acid","HMDB0006547","Unsaturated fatty acids",0.013547,0.27064,null,"12a-Hydroxy-3-oxocholadienic acid","HMDB0000385","Bile acids, alcohols and derivatives",0.0094627,2.4537]
["L-Phenylalanine","HMDB0000159","Amino acids, peptides, and analogues",1.3757,0.039006,null,"L-Cystine","HMDB0000192","Amino acids, peptides, and analogues",0.022035,7.0783,null,"Pyruvic acid","HMDB0000243","Alpha-keto acids and derivatives",0.00013216,0.32518,null,"MG(18:0/0:0/0:0)","HMDB0011131","Glycerolipids",0.039383,1.3963,null,"MG(20:3(5Z,8Z,11Z)/0:0/0:0)","HMDB0011576","Glycerolipids",0.026965,2.4273,null,"(R)-Lipoic acid","HMDB0001451","Lipoic acids and derivatives",0.0066011,2.8813,null,"7a-Hydroxy-cholestene-3-one","HMDB0001993","Cholesterols and derivatives",0.0085232,1.3548,null,"Hyocholic acid","HMDB0000760","Bile acids, alcohols and derivatives",0.0077913,67.301,null,"Hyocholic acid","HMDB0000760","Bile acids, alcohols and derivatives",0.0065879,60.811,null,"(R)-Lipoic acid","HMDB0001451","Lipoic acids and derivatives",0.0032125,2.8052]
["L-Threonine","HMDB0000167","Amino acids, peptides, and analogues",1.8738,0.0080647,null,"LysoPE(22:2(13Z,16Z)/0:0)","HMDB0011522","Glycerophospholipids",0.0081432,3.6408,null,"Adrenoyl ethanolamide","HMDB0013626","Amines",0.014669,1.6772,null,"3-Oxo-4,6-choladienoic acid","HMDB0000476","Bile acids, alcohols and derivatives",0.047257,2.3289,null,"13-OxoODE","HMDB0004668","Lineolic acids and derivatives",0.015115,0.29092,null,"L-Cystine","HMDB0000192","Amino acids, peptides, and analogues",0.015892,8.6962,null,"3-Oxohexadecanoic acid","HMDB0010733","Fatty acids and conjugates",0.034761,0.33494,null,"MG(20:3(5Z,8Z,11Z)/0:0/0:0)","HMDB0011576","Glycerolipids",0.023778,2.2425,null,"Lithocholic acid glycine conjugate","HMDB0000698","Bile acids, alcohols and derivatives",0.0023157,4.3172,null,"Hyocholic acid","HMDB0000760","Bile acids, alcohols and derivatives",0.002666,43.553]
["L-Asparagine","HMDB0000168","Amino acids, peptides, and analogues",3.3202,0.00032063,null,"Hyocholic acid","HMDB0000760","Bile acids, alcohols and derivatives",0.012155,62.312,null,"Sphingosine","HMDB0000252","Amines",0.04557,1.4019,null,"Methionine sulfoxide","HMDB0002005","Amino acids, peptides, and analogues",0.04686,1.8915,null,"LysoPC(22:2(13Z,16Z)/0:0)","HMDB0010400","Glycerophospholipids",0.0016121,0.087138,null,"PE(14:1(9Z)/14:0)","HMDB0008854","Glycerophospholipids",0.010026,0.30708,null,"MG(20:3(5Z,8Z,11Z)/0:0/0:0)","HMDB0011576","Glycerolipids",0.0058185,5.0289,null,"5a-Cholestane-3a,7a,12a,25-tetrol","HMDB0000520","Glycerophospholipids",0.038761,0.45955,null,"MG(18:3(6Z,9Z,12Z)/0:0/0:0)","HMDB0011569","Lineolic acids and derivatives",0.00092304,0.096936,null,"Lithocholic acid glycine conjugate","HMDB0000698","Bile acids, alcohols and derivatives",4.5236e-05,6.874]
["L-Histidine","HMDB0000177","Amino acids, peptides, and analogues",2.1466,0.00030132,null,"2-Hydroxymyristic acid","HMDB0002261","Fatty acids and conjugates",0.037426,0.6174,null,"Methionine sulfoxide","HMDB0002005","Amino acids, peptides, and analogues",0.019409,2.2402,null,"LysoPC(18:2(9Z,12Z)/0:0)","HMDB0010386","Glycerophospholipids",0.00064787,46853,null,"9,10-DHOME","HMDB0004704","Unsaturated fatty acids",0.00064059,0.32621,null,"Hyocholic acid","HMDB0000760","Bile acids, alcohols and derivatives",0.0051819,40.66,null,"LysoPC(22:2(13Z,16Z)/0:0)","HMDB0010400","Glycerophospholipids",0.048848,0.36759,null,"9,10-DHOME","HMDB0004704","Unsaturated fatty acids",0.0081574,0.36206,null,"Dodecanoylcarnitine","HMDB0002250","Acyl carnitines",0.017461,0.54786,null,"MG(18:3(6Z,9Z,12Z)/0:0/0:0)","HMDB0011569","Lineolic acids and derivatives",0.00026793,0.079741]
["L-Lysine","HMDB0000182","Amino acids, peptides, and analogues",1.9917,0.012829,null,"3-Hydroxytetradecanedioic acid","HMDB0000394","Fatty acids and conjugates",0.012255,0.53954,null,"o-Tyrosine","HMDB0006050","Amino acids, peptides, and analogues",0.040542,1.2526,null,"o-Tyrosine","HMDB0006050","Amino acids, peptides, and analogues",0.030762,1.2741,null,"3alpha,7alpha,12beta-Trihydroxy-5beta-cholanoic acid","HMDB0000312","Bile acids, alcohols and derivatives",0.038496,1.483,null,"Lithocholic acid glycine conjugate","HMDB0000698","Bile acids, alcohols and derivatives",6.334e-05,7.6963,null,"9,10-DHOME","HMDB0004704","Unsaturated fatty acids",0.013738,0.32752,null,"7a,12a-Dihydroxy-3-oxo-4-cholenoic acid","HMDB0000447","Bile acids, alcohols and derivatives",0.035284,2.4095,null,"9,10-DHOME","HMDB0004704","Unsaturated fatty acids",0.040832,0.60736,null,"MG(20:3(5Z,8Z,11Z)/0:0/0:0)","HMDB0011576","Glycerolipids",0.017897,3.8018]
["D-Urobilinogen","HMDB0004158","Bilirubins",0.25651,0.00056242,null,"LysoPE(0:0/14:0)","HMDB0011470","Glycerophospholipids",0.0082056,0.55636,null,"N-Arachidonoylglycine","HMDB0005096","Amino acids, peptides, and analogues",0.0030986,0.36513,null,"trans-Cinnamic acid","HMDB0000930","Cinnamic acids ",0.022187,1.6633,null,"7a,12a-Dihydroxy-3-oxo-4-cholenoic acid","HMDB0000447","Bile acids, alcohols and derivatives",0.046639,2.1348,null,"L-Carnitine","HMDB0000062","Carnitines",0.0081841,2.1686,null,"MG(20:4(5Z,8Z,11Z,14Z)/0:0/0:0)","HMDB0011578","Glycerophospholipids",0.0078212,3.8047,null,"MG(20:4(5Z,8Z,11Z,14Z)/0:0/0:0)","HMDB0011578","Glycerophospholipids",0.046715,2.1867,null,"Cysteine-S-sulfate","HMDB0000731","Amino acids, peptides, and analogues",0.046653,2.676,null,"PE(14:0/24:0)","HMDB0008848","Glycerophospholipids",0.024564,3.8089]
["Ornithine","HMDB0000214","Amino acids, peptides, and analogues",2.5921,0.024267,null,"Racemethionine","HMDB0033951","Amino acids, peptides, and analogues",0.011922,1.674,null,"L-Arginine","HMDB0000517","Amino acids, peptides, and analogues",0.01943,1.853,null,"4-Hydroxybenzoic acid","HMDB0000500","Benzoic acids and derivatives",0.042535,1.573,null,"hydroxyisovaleroyl carnitine","HMDB0062555","Acyl carnitines ",0.043844,0.31149,null,"MG(18:3(6Z,9Z,12Z)/0:0/0:0)","HMDB0011569","Lineolic acids and derivatives",0.032121,0.13145,null,"LysoPE(0:0/14:0)","HMDB0011470","Glycerophospholipids",0.044392,0.52837,null,"Racemethionine","HMDB0033951","Amino acids, peptides, and analogues",0.0015033,1.7211,null,"Chenodeoxycholic acid","HMDB0000518","Bile acids, alcohols and derivatives ",0.0075473,2.7142,null,"7a,12a-Dihydroxy-3-oxo-4-cholenoic acid","HMDB0000447","Bile acids, alcohols and derivatives",0.018485,2.3265]
["Pyruvic acid","HMDB0000243","Alpha-keto acids and derivatives",0.37284,0.0034946,null,"LysoPC(20:3(5Z,8Z,11Z)/0:0)","HMDB0010393","Glycerophospholipids",0.019391,3.6176,null,"L-Serine","HMDB0000187","Amino acids, peptides, and analogues",0.037252,1.6463,null,"LysoPC(14:0/0:0)","HMDB0010379","Glycerophospholipids",0.0090139,0.20172,null,"Tetrahydrodeoxycorticosterone","HMDB0000879","Steroids and steroid derivatives",0.0032753,0.46019,null,"MG(20:3(5Z,8Z,11Z)/0:0/0:0)","HMDB0011576","Glycerolipids",0.0028305,4.8412,null,"Racemethionine","HMDB0033951","Amino acids, peptides, and analogues",0.0035751,1.5417,null,"LysoPC(20:3(5Z,8Z,11Z)/0:0)","HMDB0010393","Glycerophospholipids",0.029643,2.7824,null,"trans-Piceid","HMDB0030564","Stilbene glycosides",0.014654,0.26406,null,"Tetrahydrodeoxycorticosterone","HMDB0000879","Steroids and steroid derivatives",0.033304,0.64791]
["Riboflavin","HMDB0000244","Alloxazines and isoalloxazines ",1.8065,0.0014605,null,"N-Acetyl-L-methionine","HMDB0011745","Amino acids, peptides, and analogues",0.024056,3.5553,null,"L-Phenylalanine","HMDB0000159","Amino acids, peptides, and analogues",0.0067578,1.3027,null,"Octanal","HMDB0001140","Medium-chain aldehydes",0.0036375,3.2477,null,"3-Oxo-4,6-choladienoic acid","HMDB0000476","Bile acids, alcohols and derivatives",0.03807,1.7521,null,"LysoPC(22:2(13Z,16Z)/0:0)","HMDB0010400","Glycerophospholipids",0.033307,0.45652,null,"LysoPC(20:3(5Z,8Z,11Z)/0:0)","HMDB0010393","Glycerophospholipids",0.048223,3.0325,null,"Docosapentaenoic aci","HMDB0006528","Unsaturated fatty acids",0.031214,1.7038,null,"10Z-Heptadecenoic acid","HMDB0060038","Unsaturated fatty acids",0.00025885,0.098495,null,"10Z-Heptadecenoic acid","HMDB0060038","Unsaturated fatty acids",0.00095119,0.10824]
["Pyroglutamic acid","HMDB0000267","Amino acids, peptides, and analogues",1.5063,0.019226,null,"Docosapentaenoic acid (22n-3)","HMDB0006528","Unsaturated fatty acids",0.0060605,1.5132,null,"D-Arginine","HMDB0003416","Amino acids, peptides, and analogues",0.023003,1.8048,null,"D-Glucuronic acid","HMDB0000127","Carbohydrates and carbohydrate conjugates",0.014608,0.31918,null,"LysoPE(20:0/0:0)","HMDB0011511","Glycerophospholipids",0.041296,2.4579,null,"9,10-DHOME","HMDB0004704","Unsaturated fatty acids",0.016034,0.48653,null,"LysoPC(14:0/0:0)","HMDB0010379","Glycerophospholipids",0.0074096,3.9067,null,"N-Acetyl-L-methionine","HMDB0011745","Amino acids, peptides, and analogues",0.023286,3.4446,null,"LysoPE(0:0/14:0)","HMDB0011470","Glycerophospholipids",0.0046112,0.42655,null,"LysoPE(0:0/14:0)","HMDB0011470","Glycerophospholipids",0.00395,0.31779]
["Uridine 5'-monophosphate","HMDB0000288","Pyrimidine ribonucleotides",0.26525,0.042414,null,"5a-Cholestane-3a,7a,12a,25-tetrol","HMDB0000520","Glycerophosphoethanolamines",0.011087,0.48482,null,"3beta,17alpha-Dihydroxy-5alpha-androstane","HMDB0000412","Androstane steroids",0.008118,0.5621,null,"12,13-Epoxy-9,15-octadecadienoic acid","HMDB0031088","Unsaturated fatty acids",0.027304,0.37339,null,"5,8,11-Eicosatrienoic acid","HMDB0010378","Unsaturated fatty acids",0.0041993,2.3118,null,"MG(20:4(5Z,8Z,11Z,14Z)/0:0/0:0)","HMDB0011578","Glycerophospholipids",0.01648,2.7406,null,"Methionine sulfoxide","HMDB0002005","Amino acids, peptides, and analogues",0.0085553,3.4258,null,"LysoPC(14:1(9Z)/0:0)","HMDB0010380","Glycerophospholipids",0.004426,0.080312,null,"Racemethionine","HMDB0033951","Amino acids, peptides, and analogues",0.0098925,1.464,null,"Racemethionine","HMDB0033951","Amino acids, peptides, and analogues",9.333e-05,1.9695]
["Uric acid","HMDB0000289","Purines and purine derivatives",3.3437,0.012808,null,"4Alpha-hydroxymethyl-5alpha-cholesta-8-en-3beta-ol","HMDB0012173","Cholesterols and derivatives",0.036751,0.37451,null,"3b-Hydroxy-5-cholenoic acid","HMDB0000308","Bile acids, alcohols and derivatives",0.0017873,2.3546,null,"3beta,17alpha-Dihydroxy-5alpha-androstane","HMDB0000412","Androstane steroids",0.049243,0.5232,null,"N-Acetyl-L-methionine","HMDB0011745","Amino acids, peptides, and analogues",0.041809,2.8032,null,"MG(0:0/22:6(4Z,7Z,10Z,13Z,16Z,19Z)/0:0)","HMDB0011557","Glycerophospholipids",0.038612,2.012,null,"LysoPC(18:2(9Z,12Z)/0:0)","HMDB0010386","Glycerophospholipids",0.021916,4.1543,null,"Cerulenin","HMDB0015168","Oxirane carboxylic acids and derivatives",0.04874,1.878,null,"3-Oxo-4,6-choladienoic acid","HMDB0000476","Bile acids, alcohols and derivatives",0.011246,3.8921,null,"N-Undecanoylglycine","HMDB0013286","Amino acids, peptides, and analogues",0.0014582,0.4002]
["Uridine","HMDB0000296","Pyrimidine nucleosides",0.51407,0.0084934,null,"Methionine sulfoxide","HMDB0002005","Amino acids, peptides, and analogues",0.00063358,4.0223,null,"3a,7a,12a-Trihydroxy-5b-cholestan-26-al","HMDB0003533","Bile acids, alcohols and derivatives",0.040198,0.60907,null,"5-Hydroxyhexanoic acid","HMDB0000525","Fatty acids and conjugates",0.043972,1.967,null,"13-HODE","HMDB0004667","Unsaturated fatty acids",0.001732,0.17872,null,"LysoPE(0:0/14:0)","HMDB0011470","Glycerophospholipids",0.01531,0.481,null,"LysoPE(18:0/0:0)","HMDB0011130","Glycerophospholipids",0.014307,39.972,null,"5,6-Dihydrouridine","HMDB0000497","Glycosylamines",0.039009,1.6869,null,"Docosapentaenoic acid (22n-3)","HMDB0006528","Unsaturated fatty acids",0.019132,1.249,null,"(S)-9-Hydroxy-10-undecenoic acid","HMDB0032662","Unsaturated fatty acids",0.0085394,0.41855]
["3b-Hydroxy-5-cholenoic acid","HMDB0000308","Bile acids, alcohols and derivatives",1.8834,0.025734,null,"L-Homocysteic acid","HMDB0002205","Amino acids, peptides, and analogues",0.0006174,4.7812,null,"7alpha-Hydroxy-3-oxo-5beta-cholan-24-oic acid","HMDB0000503","Bile acids, alcohols and derivatives",0.015226,1.7177,null,"L-Arginine","HMDB0000517","Amino acids, peptides, and analogues",0.02931,1.7143,null,"Methionine sulfoxide","HMDB0002005","Amino acids, peptides, and analogues",0.00086533,3.3146,null,"Racemethionine","HMDB0033951","Amino acids, peptides, and analogues",0.003473,2.1637,null,"4-Trimethylammoniobutanoic acid","HMDB0001161","Fatty acids and conjugates",0.01188,1.5825,null,"3b-Hydroxy-5-cholenoic acid","HMDB0000308","Bile acids, alcohols and derivatives",0.014135,1.8616,null,"N-Undecanoylglycine","HMDB0013286","Amino acids, peptides, and analogues",0.00047052,0.38539,null,"MG(18:1(9Z)/0:0/0:0)","HMDB0011567","Glycerolipids",0.0014737,0.49124]
["3a,7a,12b-Trihydroxy-5b-cholanoic acid","HMDB0000312","Bile acids, alcohols and derivatives",1.8578,0.015716,null,"Gamma-Linolenic acid","HMDB0003073","Unsaturated fatty acids",0.024807,0.73998,null,"Allocholic acid","HMDB0000505","Bile acids, alcohols and derivatives",0.025985,2.424,null,"L-Valine","HMDB0000883","Amino acids, peptides, and analogues ",0.030182,1.6948,null,"Cholesterol","HMDB0000067","Cholesterols and derivatives",0.033707,0.24952,null,"N-Acetyl-L-methionine","HMDB0011745","Amino acids, peptides, and analogues",0.03285,3.2537,null,"Palmitoylcarnitine","HMDB0000222","Acyl carnitines",0.031901,1.5451,null,"Methionine sulfoxide","HMDB0002005","Amino acids, peptides, and analogues",0.030366,1.889,null,"(S)-9-Hydroxy-10-undecenoic acid","HMDB0032662","Unsaturated fatty acids",0.023097,0.4045,null,"3b-Hydroxy-5-cholenoic acid","HMDB0000308","Bile acids, alcohols and derivatives",0.038399,1.8328]
["2b,3a,7a,12a-Tetrahydroxy-5b-cholanoic acid","HMDB0000316","Bile acids, alcohols and derivatives",1.4977,0.018228,null,"LysoPC(18:2(9Z,12Z)/0:0)","HMDB0010386","Glycerophosphoethanolamines",0.0025071,3949.8,null,"Chenodeoxycholic acid","HMDB0000518","Bile acids, alcohols and derivatives ",0.033457,1.6966,null,"Linoelaidic acid","HMDB0006270","Unsaturated fatty acids",0.03813,0.74292,null,"12,13-DHOME","HMDB0004705","Unsaturated fatty acids",0.03527,0.42445,null,"Docosapentaenoic acid (22n-3)","HMDB0006528","Unsaturated fatty acids",0.025951,1.4857,null,"Indole-3-carboxaldehyde","HMDB0029737","Indoles",0.031459,6.2717,null,"Linoelaidic acid","HMDB0006270","Unsaturated fatty acids",0.0014408,0.095477,null,"7a-Hydroxy-cholestene-3-one","HMDB0001993","Cholesterols and derivatives",0.04591,0.77342,null,"Methionine sulfoxide","HMDB0002005","Amino acids, peptides, and analogues",0.00031032,4.3443]
["1b,3a,12a-Trihydroxy-5b-cholanoic acid","HMDB0000326","Bile acids, alcohols and derivatives",2.6722,0.0096314,null,"Biliverdin","HMDB0001008","Bilirubins",0.028578,0.70465,null,"Cholic acid","HMDB0000619","Bile acids, alcohols and derivatives ",0.016657,4.0534,null,"Dihydroferulic acid","HMDB0062121","Phenylpropanoic acids",0.026859,0.40069,null,"L-Homocysteic acid","HMDB0002205","Amino acids, peptides, and analogues",0.035267,1.8516,null,"13-HODE","HMDB0004667","Unsaturated fatty acids",0.0062732,0.20419,null,"N-Acetylhistamine","HMDB0013253","Carboxylic acid derivatives",0.031315,0.40428,null,"Undecylenic acid","HMDB0033724","Unsaturated fatty acids",0.0061365,3.7566,null,"3b-Hydroxy-5-cholenoic acid","HMDB0000308","Bile acids, alcohols and derivatives",0.00036965,3.4345,null,"Undecylenic acid","HMDB0033724","Unsaturated fatty acids",0.039212,2.4288]
["3a,4b,12a-Trihydroxy-5b-cholanoic acid","HMDB0000330","Bile acids, alcohols and derivatives",2.1916,0.0076041,null,"N-Acetylgalactosamine","HMDB0000212","Carbohydrates and carbohydrate conjugates",0.038575,1.3343,null,"Urobilinogen","HMDB0004158","Bilirubins",0.030999,0.41527,null,"LysoPC(16:1(9Z)/0:0)","HMDB0010383","Glycerophospholipids",0.029744,0.38587,null,"Gamma-Linolenic acid","HMDB0003073","Unsaturated fatty acids",0.041466,0.59654,null,"(S)-9-Hydroxy-10-undecenoic acid","HMDB0032662","Unsaturated fatty acids",0.014769,0.54894,null,"PG(18:0/22:5(4Z,7Z,10Z,13Z,16Z))","HMDB0010612","Glycerophospholipids",0.0096111,0.30404,null,"3b,12a-Dihydroxy-5a-cholanoic acid","HMDB0000348","Bile acids, alcohols and derivatives",0.039935,0.32386,null,"Adrenoyl ethanolamide","HMDB0013626","Amines",0.013043,1.8554,null,"12,13-Epoxy-9,15-octadecadienoic acid","HMDB0031088","Unsaturated fatty acids",0.028939,0.38455]
["3b,12a-Dihydroxy-5a-cholanoic acid","HMDB0000348","Bile acids, alcohols and derivatives",7.2122,0.0096026,null,"LysoPE(18:0/0:0)","HMDB0011130","Glycerophospholipids",0.023177,54.927,null,"D-Glucuronic acid","HMDB0000127","Carbohydrates and carbohydrate conjugates",0.012582,0.16817,null,"6-Hydroxynicotinic acid","HMDB0002658","Pyridinecarboxylic acids and derivatives",4.9e-07,0.031928,null,"Biliverdin","HMDB0001008","Bilirubins",0.022827,0.6141,null,"Methionine sulfoxide","HMDB0002005","Amino acids, peptides, and analogues",0.036342,2.4953,null,"o-Tyrosine","HMDB0006050","Amino acids, peptides, and analogues",0.0037941,1.5018,null,"Deoxyinosine","HMDB0000071","Purine nucleosides",0.0096553,0.082066,null,"Methionine sulfoxide","HMDB0002005","Amino acids, peptides, and analogues",0.0026284,3.5254,null,"L-Homocysteic acid","HMDB0002205","Amino acids, peptides, and analogues",0.0070705,2.4213]
["3a,7a-Dihydroxycoprostanic acid","HMDB0000359","Bile acids, alcohols and derivatives",0.53612,0.015013,null,"4-Trimethylammoniobutanoic acid","HMDB0001161","Fatty acids and conjugates",0.029766,1.4831,null,"Dihydroxyacetone phosphate","HMDB0001473","Carbohydrates and carbohydrate conjugates ",0.026313,0.77848,null,"D-Tryptophan","HMDB0013609","Indoles and derivatives",0.042622,1.3378,null,"LysoPE(18:0/0:0)","HMDB0011130","Glycerophospholipids",0.031354,13.607,null,"Linoelaidic acid","HMDB0006270","Unsaturated fatty acids",0.010682,0.15211,null,"Urobilinogen","HMDB0004158","Bilirubins",0.04519,0.63914,null,"LysoPC(18:2(9Z,12Z)/0:0)","HMDB0010386","Glycerophospholipids",0.00078533,57898,null,"12,13-DHOME","HMDB0004705","Unsaturated fatty acids",0.042493,0.5276,null,"LysoPC(18:2(9Z,12Z)/0:0)","HMDB0010386","Glycerophospholipids",0.0021563,14.527]
["3b,17b-Dihydroxyetiocholane","HMDB0000369","Steroids and steroid derivatives",0.46555,0.014164,null,"Palmitoylcarnitine","HMDB0000222","Acyl carnitines",0.013113,1.5679,null,"N1-Acetylspermidine","HMDB0001276","Carboximidic acids and derivatives，N1-乙酰亚精胺是一种多胺。在许多生物中，多胺来源于L-鸟氨酸和蛋氨酸",0.0098873,0.57036,null,"D-Lysine","HMDB0003405","Amino acids, peptides, and analogues",0.013036,1.353,null,"Palmitoylcarnitine","HMDB0000222","Acyl carnitines",0.0011808,1.977,null,"L-Homocysteic acid","HMDB0002205","Amino acids, peptides, and analogues",0.0018587,3.4035,null,"Oleoylcarnitine","HMDB0005065","Acyl carnitines",0.0019062,2.0745,null,"Biliverdin","HMDB0001008","Bilirubins",0.04051,0.77414,null,"Undecylenic acid","HMDB0033724","Unsaturated fatty acids",0.027512,2.6023,null,"7-Dehydrodesmosterol","HMDB0003896","Cholesterols and derivatives",4.5319e-05,0.22052]
["12a-Hydroxy-3-oxocholadienic acid","HMDB0000385","Bile acids, alcohols and derivatives",3.1239,0.0040044,null,"Glycerophosphocholine","HMDB0000086","Glycerophospholipids",0.04025,3.7434,null,"4Alpha-hydroxymethyl-5alpha-cholesta-8-en-3beta-ol","HMDB0012173","Cholesterols and derivatives",0.031334,0.24921,null,"Oleic acid","HMDB0000207","Unsaturated fatty acids",0.047027,0.62196,null,"PC(O-18:1(9Z)/18:0)","HMDB0013427","Glycerophosphocholines",0.022811,1.6986,null,"LysoPC(18:2(9Z,12Z)/0:0)","HMDB0010386","Glycerophospholipids",0.0060427,437.38,null,"trans-Cinnamic acid","HMDB0000930","Cinnamic acids ",0.016753,1.7912,null,"Indole-3-carboxaldehyde","HMDB0029737","Indoles",0.0088098,7.0384,null,"12,13-Epoxy-9,15-octadecadienoic acid","HMDB0031088","Unsaturated fatty acids",0.04,0.37695,null,"3a,12b-Dihydroxy-5b-cholanoic acid","HMDB0000411","Bile acids, alcohols and derivatives ",0.031562,1.8806]
["3-Hydroxydodecanoic acid","HMDB0000387","Medium-chain hydroxy acids and derivatives",0.53832,0.012402,null,"Indole-3-carboxaldehyde","HMDB0029737","Indoles",0.0092669,0.70054,null,"trans-Cinnamic acid","HMDB0000930","Cinnamic acids ",0.04577,1.7192,null,"Isobutyryl-L-carnitine","HMDB0000736","Acyl carnitines",0.0072293,1.7698,null,"Hexanoylcarnitine","HMDB0000756","Acyl carnitines",0.032725,1.9724,null,"LysoPE(18:0/0:0)","HMDB0011130","Glycerophospholipids",0.0093187,155.14,null,"4-Hydroxybenzoic acid","HMDB0000500","Benzoic acids and derivatives",0.015396,1.8007,null,"Glycerophosphocholine","HMDB0000086","Glycerophospholipids",0.024108,3.7498,null,"L-Homocysteic acid","HMDB0002205","Amino acids, peptides, and analogues",0.02969,1.9457,null,"7-Dehydrocholesterol","HMDB0000032","Cholesterols and derivatives",0.0030227,0.41565]
["7-Ketodeoxycholic acid","HMDB0000391","Bile acids, alcohols and derivatives",1.7723,0.0066103,null,"o-Tyrosine","HMDB0006050","Amino acids, peptides, and analogues",0.0064022,1.7364,null,"3-Oxohexadecanoic acid","HMDB0010733","Fatty acids and conjugates",0.010321,0.47006,null,"N-Acetylneuraminic acid","HMDB0000230","Carbohydrates and carbohydrate conjugates",0.030479,0.71239,null,"Cervonoyl ethanolamide","HMDB0013627","Fatty acid esters",0.039846,1.5288,null,"Indole-3-carboxaldehyde","HMDB0029737","Indoles",0.029925,9.566,null,"Linolenelaidic acid","HMDB0030964","Unsaturated fatty acids",0.023379,0.44146,null,"9,12,13-TriHOME","HMDB0004708","Unsaturated fatty acids",0.023873,0.39864,null,"LysoPC(18:2(9Z,12Z)/0:0)","HMDB0010386","Glycerophospholipids",0.00057855,414220,null,"4-Trimethylammoniobutanoic acid","HMDB0001161","Fatty acids and conjugates",0.003271,1.7301]
["3-Hydroxytetradecanedioic acid","HMDB0000394","Fatty acids and conjugates",1.8012,0.042813,null,"3-Hydroxydodecanoic acid","HMDB0000387","Medium-chain hydroxy acids and derivatives",0.0097953,0.60433,null,"Citramalic acid","HMDB0000426","Fatty acids and conjugates",0.019167,0.69217,null,"L-Histidine","HMDB0000177","Amino acids, peptides, and analogues",0.016622,1.5489,null,"LysoPC(18:2(9Z,12Z)/0:0)","HMDB0010386","Glycerophospholipids",0.042914,0.45793,null,"Glycerophosphocholine","HMDB0000086","Glycerophospholipids",0.0056256,7.1226,null,"Kynurenic acid","HMDB0000715","Quinolines and derivatives",0.043537,0.73831,null,"Hexadecanedioic acid mono-L-carnitine ester","HMDB0000712","Acyl carnitines",0.028758,1.7321,null,"7-Dehydrodesmosterol","HMDB0003896","Cholesterols and derivatives",0.016265,0.54318,null,"Glycerophosphocholine","HMDB0000086","Glycerophospholipids",0.047515,3.4714]
["3,7-Dihydroxy-12-oxocholanoic acid","HMDB0000400","Bile acids, alcohols and derivatives",1.8293,0.019701,null,"Urobilinogen","HMDB0004158","Bilirubins",0.049169,0.70067,null,"3-Hydroxytetradecanedioic acid","HMDB0000394","Fatty acids and conjugates",0.025299,1.9157,null,"N-Acetyl-a-neuraminic acid","HMDB0000773","Carbohydrates and carbohydrate conjugates",0.027915,0.68182,null,"LysoPE(20:1(11Z)/0:0)","HMDB0011512","Glycerophospholipids",0.046679,1.9049,null,"PC(O-18:1(9Z)/18:0)","HMDB0013427","Glycerophosphocholines",0.00091369,1.9788,null,"LysoPE(18:1(11Z)/0:0)","HMDB0011505","Glycerophospholipids",0.018741,1.8146,null,"Citramalic acid","HMDB0000426","Fatty acids and conjugates",0.0058941,0.65131,null,"Indole-3-carboxaldehyde","HMDB0029737","Indoles",0.0050864,11.479,null,"Citramalic acid","HMDB0000426","Fatty acids and conjugates",9.2309e-05,0.48276]
["3b,17a-Dihydroxy-5a-androstane","HMDB0000412","Steroids and steroid derivatives",0.39166,0.0012488,null,"Oleoylcarnitine","HMDB0005065","Acyl carnitines",0.012732,1.6537,null,"2-Hydroxyhexadecanoic acid","HMDB0031057","Fatty acids and conjugates ",0.035002,0.54967,null,"L-Asparagine","HMDB0000168","Amino acids, peptides, and analogues",0.013225,2.5975,null,"2-Methylbenzaldehyde","HMDB0029636","Benzoyl derivatives",0.024566,0.33203,null,"alpha-Linolenic acid","HMDB0001388","Unsaturated fatty acids",0.012968,0.4682,null,"L-Arginine","HMDB0000517","Amino acids, peptides, and analogues",0.037199,1.6094,null,"24-Hydroxycholesterol","HMDB0001419","Bile acids, alcohols and derivatives",0.040681,0.64468,null,"Citramalic acid","HMDB0000426","Fatty acids and conjugates",0.033178,0.71165,null,"24-Hydroxycholesterol","HMDB0001419","Bile acids, alcohols and derivatives",0.017391,1.7944]
["Nutriacholic acid","HMDB0000467","Bile acids, alcohols and derivatives",1.6125,0.045905,null,"trans-Cinnamic acid","HMDB0000930","Cinnamic acids ",0.0040699,2.8,null,"MG(20:3(5Z,8Z,11Z)/0:0/0:0)","HMDB0011576","Glycerolipids",0.038864,2.8845,null,"L-Phenylalanine","HMDB0000159","Amino acids, peptides, and analogues",0.010794,1.2666,null,"Oleoylcarnitine","HMDB0005065","Acyl carnitines",0.0063317,1.7387,null,"Cervonoyl ethanolamide","HMDB0013627","Fatty acid esters",0.032043,1.4934,null,"LysoPE(20:4(5Z,8Z,11Z,14Z)/0:0)","HMDB0011517","Glycerophospholipids",0.04787,3.2108,null,"Allocholic acid","HMDB0000505","Bile acids, alcohols and derivatives",0.038285,2.1018,null,"Undecanoylcarnitine","HMDB0013321","Acyl carnitines",0.042787,0.45999,null,"Cervonoyl ethanolamide","HMDB0013627","Fatty acid esters",0.0072332,2.0388]
["3-Oxo-4,6-choladienoic acid","HMDB0000476","Bile acids, alcohols and derivatives",1.8256,0.012778,null,"LysoPC(14:0/0:0)","HMDB0010379","Glycerophospholipids",0.0075765,0.21606,null,"LysoPC(18:2(9Z,12Z)/0:0)","HMDB0010386","Glycerophosphoethanolamines",0.030609,73.107,null,"L-Tryptophan","HMDB0000929","Indoles and derivatives",0.0062159,1.455,null,"trans-Cinnamic acid","HMDB0000930","Cinnamic acids ",0.0096162,1.8441,null,"LysoPE(20:1(11Z)/0:0)","HMDB0011512","Glycerophospholipids",0.037983,1.9999,null,"6-Hydroxynicotinic acid","HMDB0002658","Pyridinecarboxylic acids and derivatives",6.5452e-08,0.021728,null,"o-Tyrosine","HMDB0006050","Amino acids, peptides, and analogues",0.0017513,1.6269,null,"o-Tyrosine","HMDB0006050","Amino acids, peptides, and analogues",0.00060423,1.5941,null,"\t1b,3a,12a-Trihydroxy-5b-cholanoic acid","HMDB0000326","Bile acids, alcohols and derivatives",0.044043,2.1462]
["4-Hydroxybenzoic acid","HMDB0000500","Benzoic acids and derivatives",1.8778,0.01091,null,"4-(2-Aminophenyl)-2,4-dioxobutanoic acid","HMDB0000978","Carbonyl compounds",0.030595,1.6727,null,"LysoPE(0:0/14:0)","HMDB0011470","Glycerophospholipids",0.018746,0.65472,null,"Pyruvic acid","HMDB0000243","Alpha-keto acids and derivatives",0.031626,0.48695,null,"MG(18:3(6Z,9Z,12Z)/0:0/0:0)","HMDB0011569","Lineolic acids and derivatives",0.043121,0.57811,null,"o-Tyrosine","HMDB0006050","Amino acids, peptides, and analogues",0.0006376,2.3211,null,"D-Tryptophan","HMDB0013609","Indoles and derivatives",0.0099466,1.4898,null,"N-Acetylgalactosamine","HMDB0000212","Carbohydrates and carbohydrate conjugates",0.020041,0.59305,null,"alpha-Linolenic acid","HMDB0001388","Unsaturated fatty acids",0.013372,0.22506,null,"3-Oxo-4,6-choladienoic acid","HMDB0000476","Bile acids, alcohols and derivatives",0.032465,1.939]
["3-Oxocholic acid","HMDB0000502","Bile acids, alcohols and derivatives",2.1536,0.001651,null,"Octanal","HMDB0001140","Medium-chain aldehydes",0.019414,2.2781,null,"Ferulic acid","HMDB0000954","Hydroxycinnamic acids and derivatives ",0.016855,0.40378,{"$nulls":7},"3-Oxocholic acid","HMDB0000502","Bile acids, alcohols and derivatives",0.028196,1.699,null,"trans-Cinnamic acid","HMDB0000930","Cinnamic acids ",0.00047811,3.2518,null,"LysoPC(20:3(8Z,11Z,14Z)/0:0)","HMDB0010394","Glycerophospholipids",0.038392,3.1582,null,"trans-Cinnamic acid","HMDB0000930","Cinnamic acids ",0.00036944,2.9726,null,"trans-Cinnamic acid","HMDB0000930","Cinnamic acids ",0.0065267,2.0825,null,"o-Tyrosine","HMDB0006050","Amino acids, peptides, and analogues",0.00021104,1.8263]
["7a-Hydroxy-3-oxo-5b-cholanoic acid","HMDB0000503","Bile acids, alcohols and derivatives",1.6046,0.010853,null,"D-Glucuronic acid","HMDB0000127","Carbohydrates and carbohydrate conjugates",0.0024526,0.30101,null,"Indole-3-carboxaldehyde","HMDB0029737","Indoles",0.043057,0.65038,{"$nulls":7},"LysoPC(14:0/0:0)","HMDB0010379","Glycerophospholipids",0.045676,0.31156,null,"LysoPC(14:0/0:0)","HMDB0010379","Glycerophospholipids",0.039111,0.22775,null,"Cytosine","HMDB0000630","Pyrimidines and pyrimidine derivatives",0.015025,1.9419,null,"N-Acetylmuramate","HMDB0060493","Carbohydrates and carbohydrate conjugates ",0.029675,0.55029,null,"MG(18:3(6Z,9Z,12Z)/0:0/0:0)","HMDB0011539","Lineolic acids and derivatives ",0.044411,0.41344,null,"alpha-Linolenic acid","HMDB0001388","Unsaturated fatty acids",0.010232,0.27275]
["Allocholic acid","HMDB0000505","Bile acids, alcohols and derivatives",1.8673,0.044067,null,"2-Keto-3-deoxy-D-gluconic acid","HMDB0001353","Keto acids and derivatives ",0.045522,0.52751,null,"13-OxoODE","HMDB0004668","Lineolic acids and derivatives",0.01126,0.27796,{"$nulls":7},"2-Keto-3-deoxy-D-gluconic acid","HMDB0001353","Keto acids and derivatives ",0.025127,0.25786,null,"Linolenelaidic acid","HMDB0030964","Unsaturated fatty acids",0.026361,0.38926,null,"Indoleacrylic acid","HMDB0000734","Indoles",0.03583,1.5925,null,"4-Hydroxybenzoic acid","HMDB0000500","Benzoic acids and derivatives",0.00034252,3.0172,null,"MG(0:0/18:3(9Z,12Z,15Z)/0:0)","HMDB0011540","Lineolic acids and derivatives",0.0081866,0.17869,null,"Oleoylcarnitine","HMDB0005065","Acyl carnitines",0.0020329,2.0514]
["L-Arginine","HMDB0000517","Amino acids, peptides, and analogues",2.1413,0.005654,null,"Adenine","HMDB0000034","Purines and purine derivatives",0.008568,0.34177,null,"MG(18:3(6Z,9Z,12Z)/0:0/0:0)","HMDB0011569","Lineolic acids and derivatives",0.041817,0.63967,{"$nulls":7},"Indole-3-carboxaldehyde","HMDB0029737","Indoles",0.0030187,0.50034,null,"D-Glucuronic acid","HMDB0000127","Carbohydrates and carbohydrate conjugates",0.0050149,0.23525,null,"DL-2-Aminooctanoic acid","HMDB0000991","Amino acids, peptides, and analogues",0.048492,1.603,null,"LysoPC(14:0/0:0)","HMDB0010379","Glycerophospholipids",0.015681,0.16341,null,"D-Glucuronic acid","HMDB0000127","Carbohydrates and carbohydrate conjugates",0.00033077,0.26355,null,"trans-Cinnamic acid","HMDB0000930","Cinnamic acids ",0.00011429,3.0073]
["Chenodeoxycholic acid","HMDB0000518","Bile acids, alcohols and derivatives ",1.9073,0.017786,null,"Kynurenic acid","HMDB0000715","Quinolines and derivatives",0.029814,0.67011,null,"MG(0:0/18:3(9Z,12Z,15Z)/0:0)","HMDB0011540","Lineolic acids and derivatives",0.0059699,0.31209,{"$nulls":7},"Adenine","HMDB0000034","Purines and purine derivatives",0.046315,0.33385,null,"Alpha-Linolenoyl ethanolamide","HMDB0013624","Amines",0.042568,0.53971,null,"L-Glutamine","HMDB0000641","Amino acids, peptides, and analogues",0.0091153,1.7014,null,"4-(2-Aminophenyl)-2,4-dioxobutanoic acid","HMDB0000978","Carbonyl compounds",0.0083415,1.7426,null,"N-Arachidonoylglycine","HMDB0005096","Amino acids, peptides, and analogues",0.018591,0.29143,null,"3-Oxocholic acid","HMDB0000502","Bile acids, alcohols and derivatives",0.038004,1.662]
["5a-Cholestane-3a,7a,12a,25-tetrol","HMDB0000520","Glycerophospholipids",0.31087,3.07e-05,null,"trans-2-Tetradecenoylcarnitine","HMDB0013329","Acyl carnitines ",0.023521,0.50937,null,"MG(18:2(9Z,12Z)/0:0/0:0)","HMDB0011568","Lineolic acids and derivatives ",0.0010569,0.42543,{"$nulls":7},"Kynurenic acid","HMDB0000715","Quinolines and derivatives",0.0061664,0.52951,null,"12,13-Epoxy-9,15-octadecadienoic acid","HMDB0031088","Unsaturated fatty acids",0.0029028,0.35903,null,"D-Lysine","HMDB0003405","Amino acids, peptides, and analogues",0.017389,1.443,null,"Linolenelaidic acid","HMDB0030964","Unsaturated fatty acids",0.0069682,0.40328,null,"2-Keto-3-deoxy-D-gluconic acid","HMDB0001353","Keto acids and derivatives ",0.0093661,0.30776,null,"LysoPC(14:0/0:0)","HMDB0010379","Glycerophospholipids",0.020337,0.22652]
["Cinnamic acid","HMDB0000567","Cinnamic acids",1.8388,0.036789,null,"LysoPE(18:1(11Z)/0:0)","HMDB0011505","Glycerophospholipids",0.038736,1.6999,null,"MG(0:0/18:1(9Z)/0:0)","HMDB0011537","Monoradylglycerols",0.03338,0.60459,{"$nulls":7},"Uridine","HMDB0000296","Pyrimidine nucleosides",0.028687,0.49588,null,"Urobilin","HMDB0004160","Bilirubins",0.007812,0.36232,null,"Malonic acid","HMDB0000691","Carboxylic acids and derivatives",0.011003,0.43359,null,"7-Ketodeoxycholic acid","HMDB0000391","Bile acids, alcohols and derivatives",0.012892,1.7025,null,"Urobilin","HMDB0004160","Bilirubins",7.6481e-05,0.36854,null,"MG(0:0/18:3(9Z,12Z,15Z)/0:0)","HMDB0011540","Lineolic acids and derivatives",0.0082635,0.34504]
["Glutarylglycine","HMDB0000590","Amino acids, peptides, and analogues",1.6669,0.047952,null,"L-Arginine","HMDB0000517","Amino acids, peptides, and analogues",2.2105e-05,4.6034,null,"Dihydroferulic acid","HMDB0062121","Phenylpropanoic acids",0.0066837,0.26554,{"$nulls":7},"N-Acetyl-L-glutamic acid","HMDB0001138","Amino acids, peptides, and analogues",0.026457,2.0059,null,"L-2-Amino-3-(1-pyrazolyl)propanoic acid","HMDB0034267","Amino acids, peptides, and analogues",0.00010334,3.0774,null,"D-Glutamine","HMDB0003423","Amino acids, peptides, and analogues",0.043614,1.3753,null,"12,13-Epoxy-9,15-octadecadienoic acid","HMDB0031088","Unsaturated fatty acids",0.0016756,0.29042,null,"Kynurenic acid","HMDB0000715","Quinolines and derivatives",0.030754,0.67637,null,"LysoPE(0:0/18:2(9Z,12Z))","HMDB0011477","Glycerophospholipids",0.01793,0.59897]
["Cholic acid","HMDB0000619","Bile acids, alcohols and derivatives ",2.3596,0.047222,null,"L-Tyrosine","HMDB0000158","Amino acids, peptides, and analogues",0.0096678,2.3448,null,"6-Hydroxynicotinic acid","HMDB0002658","Pyridinecarboxylic acids and derivatives",1.89e-05,0.058743,{"$nulls":7},"Linoelaidic acid","HMDB0006270","Unsaturated fatty acids",0.014367,0.54085,null,"Adenine","HMDB0000034","Purines and purine derivatives",0.0082426,0.38409,null,"Pyridine","HMDB0000926","Pyridines and derivatives",0.0020124,1.3056,null,"Urobilin","HMDB0004160","Bilirubins",0.00087754,0.51516,null,"L-Urobilin","HMDB0004159","Bilirubins",0.0018889,0.46039,null,"D-Glucuronic acid","HMDB0000127","Carbohydrates and carbohydrate conjugates",0.024177,0.29052]
["Deoxycholic acid","HMDB0000626","Bile acids, alcohols and derivatives",2.0965,0.041793,null,"L-Isoleucine","HMDB0000172","Amino acids, peptides, and analogues",0.028924,3.6547,null,"Kynurenic acid","HMDB0000715","Quinolines and derivatives",0.011276,0.64297,{"$nulls":7},"Dihydroferulic acid","HMDB0062121","Phenylpropanoic acids",0.017576,0.28722,null,"Ferulic acid","HMDB0000954","Hydroxycinnamic acids and derivatives",0.025908,0.65718,null,"L-Serine","HMDB0000187","Amino acids, peptides, and analogues",0.043108,1.3563,null,"3beta,17alpha-Dihydroxy-5alpha-androstane","HMDB0000412","Androstane steroids",0.023746,1.7028,null,"Cholesteryl acetate","HMDB0003822","Cholesteryl esters",0.0090823,1.5996,null,"N-Arachidonoylglycine","HMDB0005096","Amino acids, peptides, and analogues",0.03233,0.34006]
["L-Glutamine","HMDB0000641","Amino acids, peptides, and analogues",1.5677,0.023161,null,"Leucylproline","HMDB0011175","Amino acids, peptides, and analogues",0.041453,1.3806,null,"Tetrahydrodeoxycorticosterone","HMDB0000879","Steroids and steroid derivatives",0.03087,0.44362,{"$nulls":7},"6-Hydroxynicotinic acid","HMDB0002658","Pyridinecarboxylic acids and derivatives",5.0041e-07,0.036955,null,"L-Urobilin","HMDB0004159","Bilirubins",0.022436,0.45675,null,"L-Histidine","HMDB0000177","Amino acids, peptides, and analogues",0.029624,1.5577,null,"5-Hydroxyhexanoic acid","HMDB0000525","Fatty acids and conjugates",0.017753,2.2776,null,"N-Acetyl-L-glutamic acid","HMDB01138","Amino acids, peptides, and analogues",0.048957,1.7147,null,"Urobilin","HMDB0004160","Bilirubins",0.00072773,0.42993]
["Linoleic acid","HMDB0000673","Unsaturated fatty acids",4.7874,0.00032963,null,"Leukotriene E3","HMDB0002355","Eicosanoids",0.021305,2.5739,null,"Campesterol","HMDB0002869","Steroids and steroid derivatives",0.037986,0.56411,{"$nulls":7},"5-Hydroxyindoleacetic acid","HMDB0000763","Indoles and derivatives",0.0051929,0.47611,null,"L-Acetylcarnitine","HMDB0000201","Acyl carnitines",0.049772,2.5009,null,"Linoleamide","HMDB0062656","Fatty amides",0.012121,0.65014,null,"Kynurenic acid","HMDB0000715","Quinolines and derivatives",0.028025,0.67195,null,"3b,17b-Dihydroxyetiocholane","HMDB0000369","Androstane steroid",0.032148,0.49369,null,"MG(16:0/0:0/0:0)","HMDB0011564","Glycerolipids",0.044197,0.72689]
["L-Methionine","HMDB0000696","Amino acids, peptides, and analogues",1.5042,0.012218,null,"LysoPE(P-16:0/0:0)","HMDB0011152","Glycerophospholipids",0.038584,1.8835,null,"9,10-DHOME","HMDB0004704","Unsaturated fatty acids",0.017862,0.41369,{"$nulls":7},"alpha-Linolenic acid","HMDB0001388","Unsaturated fatty acids",0.037064,0.57076,null,"LysoPE(18:1(11Z)/0:0)","HMDB0011505","Glycerophospholipids",0.018225,1.8926,null,"L-Norleucine","HMDB0001645","Amino acids, peptides, and analogues",0.017918,1.4639,null,"L-Urobilin","HMDB0004159","Bilirubins",0.032061,0.65397,null,"Linoelaidic acid","HMDB0006270","Unsaturated fatty acids",0.048116,0.66285,null,"Kynurenic acid","HMDB0000715","Quinolines and derivatives",0.042776,0.58578]
["Lithocholic acid glycine conjugate","HMDB0000698","Bile acids, alcohols and derivatives",1.6099,0.046862,null,"Dihydroferulic acid","HMDB0062121","Phenylpropanoic acids",0.010753,0.28356,null,"10Z-Heptadecenoic acid","HMDB0060038","Unsaturated fatty acids",0.00010582,0.11083,{"$nulls":7},"Tetradecanoylcarnitine","HMDB0005066","Acyl carnitines",0.038494,0.41702,null,"9-Hexadecenoylcarnitine","HMDB0013207","Acyl carnitines ",0.028671,3.6695,null,"L-Tryptophan","HMDB0000929","Indoles and derivatives",0.01861,1.4888,null,"9-Hexadecenoylcarnitine","HMDB0013207","Acyl carnitines ",0.031192,2.8334,null,"Dihydroferulic acid","HMDB0062121","Phenylpropanoic acids",0.014044,0.2626,null,"L-Urobilin","HMDB0004159","Bilirubins",0.038916,0.59963]
["Kynurenic acid","HMDB0000715","Quinolines and derivatives",0.63687,0.01229,null,"LysoPC(16:1(9Z)/0:0)","HMDB0010383","Glycerophospholipids",0.0073398,0.30283,null,"Docosapentaenoic acid (22n-3)","HMDB0006528","Unsaturated fatty acids",0.048087,1.285,{"$nulls":7},"Oleic acid","HMDB0000207","Unsaturated fatty acids",0.0067093,0.4977,null,"L-Arginine","HMDB0000517","Amino acids, peptides, and analogues",9.7399e-05,3.7347,null,"L-Phenylalanine","HMDB0000159","Amino acids, peptides, and analogues",0.045582,1.3986,null,"L-Arginine","HMDB0000517","Amino acids, peptides, and analogues",0.04317,1.6367,null,"6-Hydroxynicotinic acid","HMDB0002658","Pyridinecarboxylic acids and derivatives",4.2375e-08,0.019652,null,"Uridine","HMDB0000296","Pyrimidine nucleosides",0.013744,0.48376]
["L-Pipecolic acid","HMDB0000716","Amino acids, peptides, and analogues",2.006,0.0092025,null,"6-Hydroxynicotinic acid","HMDB0002658","Pyridinecarboxylic acids and derivatives",0.00060451,0.12553,null,"13-HODE","HMDB0004667","Unsaturated fatty acids",0.0047342,0.21312,{"$nulls":7},"Malonic acid","HMDB0000691","Carboxylic acids and derivatives",0.012264,0.36902,null,"L-Tyrosine","HMDB0000158","Amino acids, peptides, and analogues",0.0047058,2.6564,null,"L-Valine","HMDB0000883","Amino acids, peptides, and analogues",0.017675,1.4152,null,"L-Isoleucine","HMDB0000172","Amino acids, peptides, and analogues",0.025888,2.5659,null,"D-Tryptophan","HMDB0013609","Indoles and derivatives",0.038282,1.3956,null,"9-Hexadecenoylcarnitine","HMDB0013207","Acyl carnitines ",0.039745,3.6964]
["Indoleacrylic acid","HMDB0000734","Indoles",1.7849,0.0098538,null,"D-Tryptophan","HMDB0013609","Indoles and derivatives",0.0023357,1.8073,null,"(S)-9-Hydroxy-10-undecenoic acid","HMDB0032662","Unsaturated fatty acids",0.028756,0.46392,{"$nulls":7},"Ricinoleic acid","HMDB0034297","Unsaturated fatty acids",0.0050117,0.13389,null,"L-Isoleucine","HMDB0000172","Amino acids, peptides, and analogues",0.0024693,12.911,null,"L-Methionine","HMDB0000696","Amino acids, peptides, and analogues",0.020024,1.5085,null,"Leukotriene E3","HMDB0002355","Eicosanoids",0.026799,2.3754,null,"4,8 Dimethylnonanoyl carnitine","HMDB0006202","Acyl carnitines",0.012828,0.44081,null,"7-Ketodeoxycholic acid","HMDB0000391","Bile acids, alcohols and derivatives",0.011425,3.5497]
["Isobutyryl-L-carnitine","HMDB0000736","Acyl carnitines",2.1962,0.00082486,null,"LysoPC(20:3(8Z,11Z,14Z)/0:0)","HMDB0010394","Glycerophospholipids",0.027016,3.5253,null,"(Z)-13-Hexadecenoic acid","HMDB0035877","Unsaturated fatty acids",0.012949,0.4867,{"$nulls":7},"4alpha-Methylzymosterol","HMDB0001217","Cholesterols and derivatives",0.018885,0.36682,null,"Leukotriene E3","HMDB0002355","Eicosanoids",0.0032746,3.3165,null,"D-Arginine","HMDB0003416","Amino acids, peptides, and analogues",0.005831,1.8994,null,"Deoxycholic acid","HMDB0000626","Bile acids, alcohols and derivatives",0.033864,2.4295,null,"5-Hydroxyindoleacetic acid","HMDB0000763","Indoles and derivatives",0.031408,0.5299,null,"13-HODE","HMDB0004667","Unsaturated fatty acids ",0.027708,0.59838]
["L-Hexanoylcarnitine","HMDB0000756","Acyl carnitines",1.6475,0.033738,null,"LysoPE(14:0/0:0)","HMDB0011500","Glycerophospholipids",0.012291,0.49465,null,"Gamma-Linolenic acid","HMDB0003073","Unsaturated fatty acids",0.026376,0.72329,{"$nulls":7},"7alpha-Hydroxy-3-oxo-5beta-cholan-24-oic acid","HMDB0000503","Bile acids, alcohols and derivatives",0.021128,1.4088,null,"LysoPE(P-16:0/0:0)","HMDB0011152","Glycerophospholipids",0.027991,2.0094,null,"L-Leucine","HMDB0000687","Amino acids, peptides, and analogues",0.0079421,1.4059,null,"6-Hydroxynicotinic acid","HMDB0002658","Pyridinecarboxylic acids and derivatives",1.7603e-07,0.016139,null,"LysoPE(14:0/0:0)","HMDB0011500","Glycerophospholipids",0.026075,0.43158,null,"Histamine","HMDB0000870","Amines",0.040749,9.6944]
["Hyocholic acid","HMDB0000760","Bile acids, alcohols and derivatives",27.021,0.032216,null,"L-Threonine","HMDB0000167","Amino acids, peptides, and analogues",0.0037977,2.4352,null,"9,12,13-TriHOME","HMDB0004708","Unsaturated fatty acids",0.029161,0.3648,{"$nulls":7},"Stearoylethanolamide","HMDB0013078","Amines",0.0087911,1.7849,null,"LysoPC(16:1(9Z)/0:0)","HMDB0010383","Glycerophospholipids",0.035781,0.36954,{"$nulls":7},"D-Tryptophan","HMDB0013609","Indoles and derivatives",0.0053645,1.6643,null,"L-Methionine","HMDB0000696","Amino acids, peptides, and analogues",0.029987,1.2667,null,"L-Tyrosine","HMDB0000158","Amino acids, peptides, and analogues",0.032512,1.9877]
["Propionylcarnitine","HMDB0000824","Acyl carnitines",0.44358,0.019924,null,"Indoleacrylic acid","HMDB0000734","Indoles",0.011487,1.9774,null,"Linolenelaidic acid","HMDB0030964","Unsaturated fatty acids",0.0034444,0.37696,{"$nulls":7},"Hydroxyvalerylcarnitine","HMDB0013132","Acyl carnitines",0.032912,1.8128,null,"6-Hydroxynicotinic acid","HMDB0002658","Pyridinecarboxylic acids and derivatives",3.8709e-07,0.036473,{"$nulls":7},"Oleoylethanolamide","HMDB0002088","Amines",0.025578,0.61629,null,"Tetradecanoylcarnitine","HMDB0005066","Acyl carnitines",0.015115,0.34523,null,"3b,17b-Dihydroxyetiocholane","HMDB0000369","Androstane steroid",0.0071501,0.39044]
["L-Valine","HMDB0000883","Amino acids, peptides, and analogues",1.5217,0.0055736,null,"DL-2-Aminooctanoic acid","HMDB0000991","Amino acids, peptides, and analogues",0.035903,1.6292,null,"12,13-Epoxy-9,15-octadecadienoic acid","HMDB0031088","Unsaturated fatty acids",0.029248,0.25985,{"$nulls":7},"Linoleic acid","HMDB0000673","Unsaturated fatty acids",0.0035802,0.27278,null,"D-Tryptophan","HMDB0013609","Indoles and derivatives",0.00063803,2.0881,{"$nulls":7},"LysoPC(20:3(8Z,11Z,14Z)/0:0)","HMDB0010394","Glycerophospholipids",0.03677,0.66292,null,"Oleic acid","HMDB0000207","Unsaturated fatty acids",0.02745,0.58749,null,"3b,12a-Dihydroxy-5a-cholanoic acid","HMDB0000348","Bile acids, alcohols and derivatives",0.043405,5.256]
["Citrulline","HMDB0000904","Amino acids, peptides, and analogues",1.4861,0.011787,null,"L-Glutamine","HMDB0000641","Amino acids, peptides, and analogues",0.0011924,2.3592,null,"alpha-Linolenic acid","HMDB0001388","Unsaturated fatty acids",0.034903,0.64555,{"$nulls":7},"2-Keto-glutaramic acid","HMDB0001552","Short-chain keto acids and derivatives",0.027734,0.53023,null,"Cytosine","HMDB0000630","Pyrimidines and pyrimidine derivatives",0.01579,2.0892,{"$nulls":7},"Cytosine","HMDB0000630","Pyrimidines and pyrimidine derivatives",0.04394,1.6488,null,"Ricinoleic acid","HMDB0034297","Unsaturated fatty acids",0.0090884,0.2169,null,"6-Hydroxynicotinic acid","HMDB0002658","Pyridinecarboxylic acids and derivatives",1.5213e-08,0.012479]
["L-Tryptophan","HMDB0000929","Indoles and derivatives",1.6354,0.0006539,null,"12,13-DHOME","HMDB0004705","Unsaturated fatty acids",0.047962,0.63256,null,"Linoelaidic acid","HMDB0006270","Unsaturated fatty acids",0.01147,0.68928,{"$nulls":7},"3-(2-Hydroxyphenyl)propanoic acid","HMDB0033752","Phenylpropanoic acids",0.018854,0.38948,null,"L-Threonine","HMDB0000167","Amino acids, peptides, and analogues",0.0035296,2.4535,{"$nulls":7},"L-Threonine","HMDB0000167","Amino acids, peptides, and analogues",0.039144,1.6652,null,"3-Hydroxytetradecanedioic acid","HMDB0000394","Fatty acids and conjugates",0.024317,2.0458,null,"D-Tryptophan","HMDB0013609","Indoles and derivatives",0.0021738,1.5996]
["trans-Cinnamic acid","HMDB0000930","Cinnamic acids ",2.7838,6.8e-05,null,"N-Acetyltryptophan","HMDB0013713","Amino acids, peptides, and analogues",0.019728,3.7554,null,"Oleic acid","HMDB0000207","Unsaturated fatty acids",0.0027703,0.58185,{"$nulls":7},"MG(18:2(9Z,12Z)/0:0/0:0)","HMDB0011568","Lineolic acids and derivatives ",0.037469,0.42862,null,"Suberic acid","HMDB0000893","Fatty acids and conjugates",0.018737,0.45085,{"$nulls":7},"Taurine","HMDB0000251","Organosulfonic acids and derivatives",0.027064,2.0602,null,"Pyridine","HMDB0000926","Pyridines and derivatives",0.0008813,1.3393,null,"5-Hydroxyindoleacetic acid","HMDB0000763","Indoles and derivatives",0.028212,0.61485]
["MG(18:2(9Z,12Z)/0:0/0:0)","HMDB0011568","Lineolic acids and derivatives ",0.29457,0.00016032,null,"D-Lysine","HMDB0003405","Amino acids, peptides, and analogues",0.00023826,2.1916,null,"12,13-DHOME","HMDB0004705","Unsaturated fatty acids",0.034615,0.52439,{"$nulls":7},"L-Phenylalanine","HMDB0000159","Amino acids, peptides, and analogues",0.042413,1.2604,null,"Palmitic amide","HMDB0012273","Fatty amides",0.029876,0.73549,{"$nulls":7},"D-Glucose","HMDB0000122","Carbohydrates and carbohydrate conjugates ",0.018747,0.61734,null,"Citrulline","HMDB0000904","Amino acids, peptides, and analogues",0.0089451,1.4378,null,"LysoPE(14:0/0:0)","HMDB0011500","Glycerophospholipids",0.0093786,0.43774]
["N-Acetylglutamic acid","HMDB0001138","Amino acids, peptides, and analogues",1.9988,0.023692,null,"Isobutyryl-L-carnitine","HMDB0000736","Acyl carnitines",0.0007168,2.7102,null,"Ricinoleic acid","HMDB0034297","Unsaturated fatty acids",0.014306,0.25703,{"$nulls":7},"Pyruvic acid","HMDB0000243","Alpha-keto acids and derivatives",0.024056,0.24637,null,"Indoleacrylic acid","HMDB0000734","Indoles",0.0021188,2.6438,{"$nulls":7},"Indoleacrylic acid","HMDB0000734","Indoles",0.0098461,1.8806,null,"Linoleic acid","HMDB0000673","Unsaturated fatty acids",0.014368,0.39553,null,"L-Threonine","HMDB0000167","Amino acids, peptides, and analogues",0.011789,1.9263]
["4a-Methylzymosterol","HMDB0001217","Cholesterols and derivatives",0.35694,0.043053,null,"D-Glutamine","HMDB0003423","Amino acids, peptides, and analogues",0.0233,1.5509,null,"Linoleic acid","HMDB0000673","Unsaturated fatty acids",0.018305,0.36549,{"$nulls":7},"4Alpha-hydroxymethyl-5alpha-cholesta-8-en-3beta-ol","HMDB0012173","Cholestane steroids",0.024294,0.32737,null,"Tetradecanoylcarnitine","HMDB0005066","Acyl carnitines",0.014907,0.54817,{"$nulls":7},"DL-2-Aminooctanoic acid","HMDB0000991","Amino acids, peptides, and analogues",0.018046,1.7358,null,"L-Histidine","HMDB0000177","Amino acids, peptides, and analogues",0.041185,1.4949,null,"4-Hydroxybenzaldehyde","HMDB0011718","Carbonyl compounds",0.038694,2.6404]
["Alpha-Linolenic acid","HMDB0001388","Unsaturated fatty acids",0.33617,0.0074041,null,"Ricinoleic acid","HMDB0034297","unsaturated fatty acid",0.044069,0.56148,{"$nulls":13},"Sphinganine","HMDB0000269","Amines",0.020165,0.76104,null,"L-Glutamine","HMDB0000641","Amino acids, peptides, and analogues",0.00051262,2.5872,{"$nulls":7},"L-Glutamine","HMDB0000641","Amino acids, peptides, and analogues",0.0015875,2.0712,null,"6-Hydroxypentadecanedioic acid","HMDB0031885","Fatty acids and conjugates",0.036946,0.61195,null,"Indoleacrylic acid","HMDB0000734","Indoles",0.0039833,1.9924]
["(R)-lipoic acid","HMDB0001451","Lipoic acids and derivatives",2.0083,0.031037,null,"Citrulline","HMDB0000904","Amino acids, peptides, and analogues",0.011404,1.5614,{"$nulls":13},"Imidazolepropionic acid","HMDB0002271","Imidazoles ",0.040256,0.53948,null,"12,13-DHOME","HMDB0004705","Unsaturated fatty acids",0.0097345,0.43973,{"$nulls":7},"12,13-DHOME","HMDB0004705","Unsaturated fatty acids",0.01077,0.35013,null,"LysoPE(15:0/0:0)","HMDB0011502","Glycerophospholipids",0.015373,0.35488,null,"Tetradecanoylcarnitine","HMDB0005066","Acyl carnitines",0.025738,0.42107]
["2-Keto-glutaramic acid","HMDB0001552","Short-chain keto acids and derivatives",0.5479,0.021622,null,"Deoxycholic acid","HMDB0000626","Bile acids, alcohols and derivatives",0.0072574,0.11799,{"$nulls":19},"N-Acetyltryptophan","HMDB0013713","Amino acids, peptides, and analogues",0.0055447,4.6518,{"$nulls":7},"Sphingosine","HMDB0000252","Amines",0.015405,0.3754,null,"L-Asparagine","HMDB0000168","Amino acids, peptides, and analogues",0.0053711,2.4192,null,"L-Glutamine","HMDB0000641","Amino acids, peptides, and analogues",0.0026455,1.9757]
["Tetradecanoylcarnitine","HMDB0005066","Acyl carnitines",0.29296,0.00029591,null,"Ursodeoxycholic acid","HMDB0000946","Bile acids, alcohols and derivatives",0.034069,0.5934,{"$nulls":19},"D-Lysine","HMDB0003405","Amino acids, peptides, and analogues",6.7559e-05,2.4075,{"$nulls":7},"N-Acetyltryptophan","HMDB0013713","Amino acids, peptides, and analogues",0.03978,2.1937,null,"LysoPE(0:0/15:0)","HMDB0011472","Glycerophospholipids",0.012999,0.45585,null,"N-Acetyltryptophan","HMDB0013713","Amino acids, peptides, and analogues",0.018862,3.1107]
["Methionine sulfoxide","HMDB0002005","Amino acids, peptides, and analogues",1.951,0.044779,null,"Dodecanedioic acid","HMDB0000623","Fatty acids and conjugates",0.048645,0.71283,{"$nulls":19},"Oleic acid","HMDB0000207","Unsaturated fatty acids",0.027543,0.54464,{"$nulls":7},"D-Lysine","HMDB0003405","Amino acids, peptides, and analogues",0.0025021,1.5125,null,"Cinnamic acid","HMDB0000567","Cinnamic acids",0.015321,2.1103,null,"D-Lysine","HMDB0003405","Amino acids, peptides, and analogues",0.00044517,1.7219]
["Oleamide","HMDB0002117","Fatty amides",1.8084,0.00046529,null,"D-Aspartic acid","HMDB0006483","Amino acids, peptides, and analogues",0.0053277,1.9472,{"$nulls":19},"Malonic acid","HMDB0000691","Carboxylic acids and derivatives",0.00012726,0.33286,{"$nulls":7},"Oleic acid","HMDB0000207","Unsaturated fatty acids",0.00074695,0.40444,null,"Methyl linoleate","HMDB0034381","Lineolic acids and derivatives",0.031643,0.50326,null,"Oleic acid","HMDB0000207","Unsaturated fatty acids",0.0094147,0.65842]
["L-Homocysteic acid","HMDB0002205","Amino acids, peptides, and analogues",3.1317,0.0016354,null,"L-Histidine","HMDB0000177","Amino acids, peptides, and analogues",0.00081722,2.3651,{"$nulls":19},"2-Aminoacrylic acid","HMDB0003609","Amino acids, peptides, and analogues",0.029189,2.6835,{"$nulls":7},"Glutaconic acid","HMDB0000620","Carboxylic acids and derivatives",0.012413,0.6581,null,"MG(18:2(9Z,12Z)/0:0/0:0)","HMDB0011568","Lineolic acids and derivatives ",0.014265,0.33616,null,"Glutaconic acid","HMDB0000620","Carboxylic acids and derivatives",0.023254,0.60917]
["Picolinic acid","HMDB0002243","Picolinic acid",0.66883,0.028073,null,"L-Serine","HMDB0000187","Amino acids, peptides, and analogues",0.0021188,2.4496,{"$nulls":19},"Ricinoleic acid","HMDB0034297","Unsaturated fatty acids",0.015014,0.2089,{"$nulls":7},"Malonic acid","HMDB0000691","Carboxylic acids and derivatives",0.0025925,0.40761,null,"L-Phenylalanine","HMDB0000159","Amino acids, peptides, and analogues",0.00040592,1.5661,null,"Malonic acid","HMDB0000691","Carboxylic acids and derivatives",0.00072652,0.38143]
["Imidazolepropionic acid","HMDB0002271","Imidazoles ",0.42143,0.034611,null,"LysoPE(15:0/0:0)","HMDB0011502","Glycerophospholipids",0.011188,0.44829,{"$nulls":19},"Isobutyryl-L-carnitine","HMDB0000736","Acyl carnitines",0.0080977,2.6774,{"$nulls":7},"Ricinoleic acid","HMDB0034297","Unsaturated fatty acids",0.0097139,0.1404,null,"L-Tryptophan","HMDB0000929","Indoles and derivatives",0.0070086,1.5362,null,"7a,12a-Dihydroxy-5b-cholestan-3-one","HMDB0006887","Cholesterols and derivatives",0.0047195,3.8314]
["Leukotriene E3","HMDB0002355","Eicosanoids",2.5186,0.016356,null,"Pyroglutamic acid","HMDB0000267","Amino acids, peptides, and analogues",0.0013667,1.9732,{"$nulls":19},"D-Glutamine","HMDB0003423","Amino acids, peptides, and analogues",0.0021166,1.9005,{"$nulls":7},"Isobutyryl-L-carnitine","HMDB0000736","Acyl carnitines",0.00016276,3.1921,null,"D-Arginine","HMDB0003416","Amino acids, peptides, and analogues",0.03722,1.6653,null,"Ricinoleic acid","HMDB0034297","Unsaturated fatty acids",0.0052976,0.23567]
["Cholic acid glucuronide","HMDB0002577","Steroids and steroid derivatives",0.38452,0.0027869,null,"L-Asparagine","HMDB0000168","Amino acids, peptides, and analogues",0.012099,2.2526,{"$nulls":19},"Hydroxyvalerylcarnitine","HMDB0013132","Acyl carnitines",0.0040674,2.2264,{"$nulls":7},"D-Glutamine","HMDB0003423","Amino acids, peptides, and analogues",0.0023571,1.6094,{"$nulls":7},"7alpha-Hydroxy-3-oxo-5beta-cholan-24-oic acid","HMDB0000503","Bile acids, alcohols and derivatives",0.026381,1.4799]
["10Z-Heptadecenoic acid","HMDB0060038","Unsaturated fatty acids",0.11125,0.0011852,null,"L-Pipecolic acid","HMDB0000716","Amino acids, peptides, and analogues",0.0054545,2.2365,{"$nulls":19},"Citrulline","HMDB0000904","Amino acids, peptides, and analogues",0.019464,1.4719,{"$nulls":7},"Pyridine","HMDB0000926","Pyridines and derivatives",0.048301,1.1943,{"$nulls":7},"3a,4b,12a-Trihydroxy-5b-cholanoic acid","HMDB0000330","Bile acids, alcohols and derivatives",0.037067,1.7723]
["12,13-Epoxy-9,15-octadecadienoic acid","HMDB0031088","Unsaturated fatty acids",0.38884,0.0012308,null,"L-Norleucine","HMDB0001645","Amino acids, peptides, and analogues",0.0047706,1.8321,{"$nulls":19},"Linoleic acid","HMDB0000673","Unsaturated fatty acids",0.024369,0.39348,{"$nulls":7},"Linoleic acid","HMDB0000673","Unsaturated fatty acids",0.0066484,0.27721,{"$nulls":7},"Sphingosine","HMDB0000252","Amines",0.03743,1.4518]
["Palmitoleic acid","HMDB0003229","Unsaturated fatty acid",0.19298,0.031576,null,"Cinnamic acid","HMDB0000567","Cinnamic acids",0.012062,2.2464,{"$nulls":19},"D-Aspartic acid","HMDB0006483","Amino acids, peptides, and analogues",0.032982,1.7179,{"$nulls":7},"Dodecanedioic acid","HMDB0000623","Fatty acids and conjugates",0.012052,0.60619,{"$nulls":7},"Citrulline","HMDB0000904","Amino acids, peptides, and analogues",0.0087481,1.6468]
["D-Lysine","HMDB0003405","Amino acids, peptides, and analogues",1.8746,0.00037796,null,"3b-Hydroxy-5-cholenoic acid","HMDB0000308","Bile acids, alcohols and derivatives",0.04124,0.59049,{"$nulls":19},"L-Histidine","HMDB0000177","Amino acids, peptides, and analogues",0.00049096,2.5862,{"$nulls":7},"D-Aspartic acid","HMDB0006483","Amino acids, peptides, and analogues",0.018118,1.7652,{"$nulls":7},"Linoleic acid","HMDB0000673","Unsaturated fatty acids",0.012914,0.43073]
["D-Arginine","HMDB0003416","Amino acids, peptides, and analogues",1.6808,0.022073,null,"L-Lysine","HMDB0000182","Amino acids, peptides, and analogues",0.0050633,2.3135,{"$nulls":19},"Linoleamide","HMDB0062656","Fatty amides",0.014916,0.57246,{"$nulls":7},"L-Histidine","HMDB0000177","Amino acids, peptides, and analogues",0.0041342,1.8472,{"$nulls":7},"12-Ketodeoxycholic acid","HMDB0000328","Bile acids, alcohols and derivatives",0.012661,1.909]
["D-Glutamine","HMDB0003423","Amino acids, peptides, and analogues",1.4889,0.0054079,null,"Piperidine","HMDB0034301","Piperidines",0.0074285,1.9732,{"$nulls":19},"Oleamide","HMDB0002117","Fatty amides",0.0247,0.72841,{"$nulls":7},"L-Serine","HMDB0000187","Amino acids, peptides, and analogues",0.0040065,2.1918,{"$nulls":7},"L-Histidine","HMDB0000177","Amino acids, peptides, and analogues",0.00074589,2.0007]
["3a,7a,12a-Trihydroxy-5b-cholestan-26-al","HMDB0003533","Bile acids, alcohols and derivatives",0.51141,0.022896,null,"Choline","HMDB0000097","Cholines",0.017996,1.7628,{"$nulls":19},"LysoPE(0:0/18:0)","HMDB0011129","Glycerophospholipids",0.039401,2.1054,{"$nulls":7},"Pyroglutamic acid","HMDB0000267","Amino acids, peptides, and analogues",0.028896,1.4901,{"$nulls":7},"L-Serine","HMDB0000187","Amino acids, peptides, and analogues",0.0044772,2.1793]
["Ricinoleic acid","HMDB0034297","unsaturated fatty acid",4.1588,0.00021942,null,"L-Glutamic acid","HMDB0000148","Amino acids, peptides, and analogues",0.0050357,1.6031,{"$nulls":19},"L-Serine","HMDB0000187","Amino acids, peptides, and analogues",0.0008716,2.6998,{"$nulls":7},"L-Asparagine","HMDB0000168","Amino acids, peptides, and analogues",0.033563,1.8661,{"$nulls":7},"Oleamide","HMDB0002117","Fatty amides",0.011186,1.5779]
["MG(0:0/18:1(9Z)/0:0)","HMDB0011537","Monoradylglycerols",0.32074,0.001134,null,"Hypoxanthine","HMDB0000157","Purines and purine derivatives",0.0028403,2.1281,{"$nulls":19},"Nutriacholic acid","HMDB0000467","Bile acids, alcohols and derivatives",0.020792,1.4854,{"$nulls":7},"L-Pipecolic acid","HMDB0000716","Amino acids, peptides, and analogues",0.023418,1.7987,{"$nulls":7},"2-Keto-glutaramic acid","HMDB0001552","Short-chain keto acids and derivatives",0.022664,0.50338]
["MG(18:1(9Z)/0:0/0:0)","HMDB0011567","Glycerolipids",0.73494,0.032176,null,"Creatine","HMDB0000064","Amino acids, peptides, and analogues",0.019694,1.7943,{"$nulls":19},"LysoPE(15:0/0:0)","HMDB0011502","Glycerophospholipids",0.0044029,0.40757,{"$nulls":7},"Coprocholic acid","HMDB0000601","Bile acids, alcohols and derivatives",0.03856,0.55943,{"$nulls":7},"Nutriacholic acid","HMDB0000467","Bile acids, alcohols and derivatives",0.035897,1.5867]
["(S)-9-Hydroxy-10-undecenoic acid","HMDB0032662","Unsaturated fatty acids",0.32802,0.0018058,null,"L-Alanine","HMDB0000161","Amino acids, peptides, and analogues",0.0036001,2.5183,{"$nulls":19},"Pyroglutamic acid","HMDB0000267","Amino acids, peptides, and analogues",0.0020761,2.0558,{"$nulls":7},"Cinnamic acid","HMDB0000567","Cinnamic acids",0.016426,2.0443,{"$nulls":7},"6-Hydroxypentadecanedioic acid","HMDB0031885","Fatty acids and conjugates",0.006673,0.4226]
["13-OxoODE","HMDB0004668","Unsaturated fatty acids",0.34006,0.0080679,null,"L-Tryptophan","HMDB0000929","Indoles and derivatives",0.0016092,2.0392,{"$nulls":19},"L-Asparagine","HMDB0000168","Amino acids, peptides, and analogues",0.0024447,2.7644,{"$nulls":7},"L-Lysine","HMDB0000182","Amino acids, peptides, and analogues",0.037323,1.7362,{"$nulls":7},"Pyroglutamic acid","HMDB0000267","Amino acids, peptides, and analogues",0.0082739,1.7176]
["9,10-DHOME","HMDB0004704","Unsaturated fatty acids",0.41461,0.036737,null,"3alpha,7alpha-Dihydroxycoprostanic acid","HMDB0000359","Bile acids, alcohols and derivatives",0.023162,0.67452,{"$nulls":19},"L-Pipecolic acid","HMDB0000716","Amino acids, peptides, and analogues",0.0084873,2.244,{"$nulls":7},"LysoPC(15:0/0:0)","HMDB0010381","Glycerophospholipids",0.017013,1.6161,{"$nulls":7},"L-Asparagine","HMDB0000168","Amino acids, peptides, and analogues",0.0055888,2.5309]
["12,13-DHOME","HMDB0004705","Unsaturated fatty acids",0.19452,0.026295,null,"L-Phenylalanine","HMDB0000159","Amino acids, peptides, and analogues",0.0058569,1.7248,{"$nulls":19},"L-Norleucine","HMDB0001645","Amino acids, peptides, and analogues",0.0028009,2.0614,{"$nulls":7},"Choline","HMDB0000097","Cholines",0.017264,1.8439,{"$nulls":7},"L-Pipecolic acid","HMDB0000716","Amino acids, peptides, and analogues",0.0029817,2.2651]
["Gamma-Linolenic acid","HMDB0003073","Unsaturated fatty acids",0.60469,0.00047016,null,"L-Valine","HMDB0000883","Amino acids, peptides, and analogues",0.0018337,1.6257,{"$nulls":19},"LysoPE(0:0/15:0)","HMDB0011472","Glycerophospholipids",0.015183,0.44468,{"$nulls":7},"L-Phenylalanine","HMDB0000159","Amino acids, peptides, and analogues",0.00022648,1.8143,{"$nulls":7},"L-Norleucine","HMDB0001645","Amino acids, peptides, and analogues",0.0070794,1.7442]
["o-Tyrosine","HMDB0006050","Amino acids, peptides, and analogues",1.6312,0.00020736,null,"L-Methionine","HMDB0000696","Amino acids, peptides, and analogues",0.00091748,2.07,{"$nulls":19},"Cinnamic acid","HMDB0000567","Cinnamic acids",0.0034849,2.7958,{"$nulls":7},"L-Alanine","HMDB0000161","Amino acids, peptides, and analogues",0.017226,2.0302,{"$nulls":7},"2-Aminoheptanedioic acid","HMDB0034252","Amino acids, peptides, and analogues",0.031211,0.51814]
["Linoelaidic acid","HMDB0006270","Unsaturated fatty acids",0.68766,0.016489,null,"D-Arginine","HMDB0003416","Amino acids, peptides, and analogues",0.00026736,2.987,{"$nulls":19},"L-Lysine","HMDB0000182","Amino acids, peptides, and analogues",0.0093713,2.2401,{"$nulls":7},"L-Tryptophan","HMDB0000929","Indoles and derivatives",0.002796,1.7966,{"$nulls":7},"L-Lysine","HMDB0000182","Amino acids, peptides, and analogues",0.0042108,2.1896]
["Docosapentaenoic acid","HMDB0006528","Unsaturated fatty acids",2.34,0.0014869,null,"Pyruvic acid","HMDB0000243","Alpha-keto acids and derivatives",0.013615,0.46392,{"$nulls":19},"Choline","HMDB0000097","Cholines",0.0049513,1.9723,{"$nulls":7},"L-Proline","HMDB0000162","Amino acids, peptides, and analogues",0.037405,1.7152,{"$nulls":7},"Tetracosahexaenoic acid","HMDB0002007","Unsaturated fatty acids",0.025947,1.5337]
["7a,12a-Dihydroxy-5a-cholestan-3-one","HMDB0006886","Cholestane steroids",0.43721,0.0012656,null,"L-Aspartic acid","HMDB0000191","Amino acids, peptides, and analogues",0.045597,1.6089,{"$nulls":19},"L-Glutamic acid","HMDB0000148","Amino acids, peptides, and analogues",0.016838,1.5652,{"$nulls":7},"L-Valine","HMDB0000883","Amino acids, peptides, and analogues",0.0083037,1.7056,{"$nulls":7},"Piperidine","HMDB0034301","Piperidines",0.0050107,2.0617]
["7a,12a-Dihydroxy-5b-cholestan-3-one","HMDB0006887","Cholesterols and derivatives",0.50585,0.010339,null,"L-Leucine","HMDB0000687","Amino acids, peptides, and analogues",0.025982,1.5616,{"$nulls":19},"Creatine","HMDB0000064","Amino acids, peptides, and analogues",0.0074595,2.1868,{"$nulls":7},"L-Methionine","HMDB0000696","Amino acids, peptides, and analogues",0.015565,1.5526,{"$nulls":7},"L-Glutamic acid","HMDB0000148","Amino acids, peptides, and analogues",0.01934,1.4925]
["PC(20:4(8Z,11Z,14Z,17Z)/20:2(11Z,14Z))","HMDB0008473","Glycerophospholipids",2.5028,0.0074319,{"$nulls":25},"MG(18:2(9Z,12Z)/0:0/0:0)","HMDB0011568","Lineolic acids and derivatives ",0.016477,0.53263,{"$nulls":7},"D-Arginine","HMDB0003416","Amino acids, peptides, and analogues",0.00048623,2.4959,{"$nulls":7},"Hypoxanthine","HMDB0000157","Purines and purine derivatives",0.011175,1.8675]
["9-HOTE","HMDB0010224","Unsaturated fatty acid",0.5474,0.038465,{"$nulls":25},"L-Alanine","HMDB0000161","Amino acids, peptides, and analogues",0.0060133,2.4638,{"$nulls":7},"Pyruvic acid","HMDB0000243","Alpha-keto acids and derivatives",0.0025755,0.31518,{"$nulls":7},"Creatine","HMDB0000064","Amino acids, peptides, and analogues",0.0085816,2.077]
["Aldosterone 18-glucuronide","HMDB0010345","Steroidal glycosides",2.1986,0.0023038,{"$nulls":25},"L-Tryptophan","HMDB0000929","Indoles and derivatives",0.00039675,2.3995,{"$nulls":7},"D-Lactic acid","HMDB0001311","Hydroxy acids and derivatives",0.042742,1.7148,{"$nulls":7},"L-Phenylalanine","HMDB0000159","Amino acids, peptides, and analogues",0.00010338,1.9082]
["LysoPC(18:2(9Z,12Z))","HMDB0010386","Glycerophospholipids",294.24,0.0095506,{"$nulls":25},"L-Phenylalanine","HMDB0000159","Amino acids, peptides, and analogues",0.0064128,1.7865,{"$nulls":7},"L-Leucine","HMDB0000687","Amino acids, peptides, and analogues",0.0017928,1.549,{"$nulls":7},"L-Alanine","HMDB0000161","Amino acids, peptides, and analogues",0.014441,2.0847]
["3-Oxohexadecanoic acid","HMDB0010733","Fatty acids and conjugates",0.42024,0.0052373,{"$nulls":25},"L-Valine","HMDB0000883","Amino acids, peptides, and analogues",0.0025703,1.9048,{"$nulls":19},"L-Tryptophan","HMDB0000929","Indoles and derivatives",0.0051819,1.6148]
["LysoPE(0:0/14:0)","HMDB0011470","Glycerophospholipids",0.53241,0.011968,{"$nulls":25},"L-Methionine","HMDB0000696","Amino acids, peptides, and analogues",0.0010699,2.1977,{"$nulls":19},"L-Proline","HMDB0000162","Amino acids, peptides, and analogues",0.029798,1.718]
["LysoPE(0:0/18:2(9Z,12Z))","HMDB0011477","Glycerophospholipids",0.30127,0.017879,{"$nulls":25},"D-Arginine","HMDB0003416","Amino acids, peptides, and analogues",8.2988e-05,4.0739,{"$nulls":19},"MG(18:2(9Z,12Z)/0:0/0:0)","HMDB0011568","Lineolic acids and derivatives",0.033723,0.53802]
["LysoPE(0:0/20:3(11Z,14Z,17Z))","HMDB0011484","Glycerophospholipids",0.25867,0.0092373,{"$nulls":25},"Pyruvic acid","HMDB0000243","Alpha-keto acids and derivatives",0.016445,0.31244,{"$nulls":19},"L-Valine","HMDB0000883","Amino acids, peptides, and analogues",0.011987,1.4338]
["LysoPE(0:0/20:3(5Z,8Z,11Z))","HMDB0011485","Glycerophospholipids",0.24149,0.033174,{"$nulls":25},"L-Leucine","HMDB0000687","Amino acids, peptides, and analogues",0.0031462,1.6825,{"$nulls":19},"L-Methionine","HMDB0000696","Amino acids, peptides, and analogues",0.0013875,1.9268]
["Oleic acid","HMDB0000207","Unsaturated fatty acids",0.57218,0.0012826,{"$nulls":25},"Piperidine","HMDB0034301","Piperidines",0.0040529,2.2562,{"$nulls":19},"D-Arginine","HMDB0003416","Amino acids, peptides, and analogues",0.00081359,2.2968]
["LysoPE(14:0/0:0)","HMDB0011500","Glycerophospholipids",0.61049,0.039695,{"$nulls":49},"Pyruvic acid","HMDB0000243","Alpha-keto acids and derivatives",0.0005641,0.38628]
["LysoPE(18:2(9Z,12Z)/0:0)","HMDB0011507","Glycerophospholipids",0.26731,0.024306,{"$nulls":49},"Deoxycholic acid","HMDB0000626","Bile acids, alcohols and derivatives",0.0099759,2.3989]
["(Z)-9-Heptadecenoic acid","HMDB0031046","Unsaturated fatty acids",0.0046368,0.00063335]
["MG(0:0/18:3(6Z,9Z,12Z)/0:0)","HMDB0011539","Lineolic acids and derivatives ",0.38979,0.0047686]
["MG(0:0/18:3(9Z,12Z,15Z)/0:0)","HMDB0011540","Lineolic acids and derivatives",0.35299,0.0034888]
["MG(16:0/0:0/0:0)","HMDB0011564","Glycerolipids",0.62476,0.02567]
["MG(16:1(9Z)/0:0/0:0)","HMDB0011565","Monoradylglycerols ",0.17398,0.025651]
["1H-Indole-3-carboxaldehyde","HMDB0029737","Indoles",30.17,0.0002891]
["Deoxycholic acid 3-glucuronide","HMDB0002596","Steroids and steroid derivatives",0.4099,0.00022615]
["Mesobilirubinogen","HMDB0001898","Bilirubins",0.48628,0.001307]
["MG(22:6(4Z,7Z,10Z,13Z,16Z,19Z)/0:0/0:0)","HMDB0011587","Monoradylglycerols ",0.351,0.02275]
["4-Hydroxybenzaldehyde","HMDB0011718","Carbonyl compounds",2.8556,0.034629]
["4Alpha-hydroxymethyl-5alpha-cholesta-8-en-3beta-ol","HMDB0012173","Cholestane steroids",0.33945,0.034172]
["PS(22:6(4Z,7Z,10Z,13Z,16Z,19Z)/18:0)","HMDB0012444",null,3.2531,0.0073278]
["Stearoylethanolamide","HMDB0013078","Amines",1.8665,0.0058348]
["Hydroxyvalerylcarnitine","HMDB0013132","Acyl carnitines",1.8571,0.024237]
["N-Decanoylglycine","HMDB0013267","Amino acids, peptides, and analogues",0.5022,0.024791]
["PC(o-18:1(9Z)/18:0)","HMDB0013427","Glycerophospholipids",1.7591,0.019528]
["D-Tryptophan","HMDB0013609","Indoles and derivatives",1.587,0.0045966]
["Alpha-Linolenoyl ethanolamide","HMDB0013624","Amines",0.60239,0.013294]
["D-Urobilin","HMDB0004161","Bilirubins",0.38528,0.0019329]
["trans-Piceid","HMDB0030564","Stilbene glycosides",0.33683,0.037028]
["trans-Ferulic acid","HMDB0000954","Hydroxycinnamic acids and derivatives",0.46433,0.00032038]
["(R)-2-Hydroxyhexadecanoic acid","HMDB0031057","Fatty acids and conjugates",1.6649,0.0074031]
["L-Urobilin","HMDB0004159","Bilirubins",0.43464,0.0021794]
["I-Urobilin","HMDB0004160","Bilirubins",0.35284,0.00011085]
["Racemethionine","HMDB0033951","Amino acids, peptides, and analogues",1.3697,0.018831]
["MG(18:3(9Z,12Z,15Z)/0:0/0:0)","HMDB0011570","Lineolic acids and derivatives",0.10479,0.0013097]
["(Z)-13-Hexadecenoic acid","HMDB0035877","Unsaturated fatty acids",0.54256,0.030553]
["LysoPE(0:0/20:4(5Z,8Z,11Z,14Z))","HMDB0011487","Glycerophospholipids",0.20782,0.0025364]
["2-Oleoylglycerophosphocholine","HMDB0061701","Glycerophospholipids",0.35673,0.01463]
["Hydroferulic acid","HMDB0062121","Phenylpropanoic acids",0.26455,0.010815]

{"sheet":"Table S6","index":5,"n_rows":16,"n_cols":19,"rows_kept":16,"cut":false,"hidden":false,"merged":[[0,0,0,11],[1,1,1,2],[1,3,1,4],[1,5,1,6],[1,7,1,8],[1,9,1,10],[1,11,1,12],[1,13,1,14],[1,15,1,16],[1,17,1,18]],"flags":["formulas_cached_only"]}
["Table S6. Effects of different polysaccharides on metabolic disorder pathways (Calculations were analyzed through the MetaboAnalyst platform). "]
[null,"Xanthan gum",null,"Inulin",null,"Guar gum",null,"Arabinogalactan",null,"Carrageenan",null,"Glucomannan",null,"Araboxylan",null,"Xylan",null,"Fucoidan"]
[null,"P value","Impact","P value","Impact","P value","Impact","P value","Impact","P value","Impact","P value","Impact","P value","Impact","P value","Impact","P value","Impact"]
["Linoleic acid metabolism",null,null,0.005441,1,null,null,0.005925,1,0.001088,1,null,null,0.001013,1,0.029318,1,0.00092,1]
["alpha-Linolenic acid metabolism",null,null,0.010528,0.33333,null,null,0.055043,0.33333,0.002331,0.33333,{"$nulls":4},0.019139,0.33333,0.000219,0.33333]
["Alanine, aspartate and glutamate metabolism",9.8e-05,0.53446,0.000453,0,0.001406,0,0.014201,0,2.06e-05,0.3109,0.07939,0.11378,0.001312,0.11378,0.002637,0,0.000201,0.3109]
["Pentose and glucuronate interconversions",0.000192,0.125,0.00669,0.125,0.005223,0.125,null,null,0.000149,0.125,{"$nulls":4},0.000355,0.125,0.001989,0.125]
["Arginine and proline metabolism",3.07e-06,0.15598,0.000297,0.05786,0.006407,0.05786,0.038199,0,4.68e-06,0.15598,0.20451,0.05786,0.000363,0.13566,null,null,0.000875,0.17592]
["Ascorbate and aldarate metabolism",0.000192,0.25,0.00669,0.25,0.005223,0.25,null,null,0.000149,0.25,{"$nulls":4},0.000355,0.25,0.001989,0.25]
["Pyruvate metabolism",0.000362,0.20684,0.000453,0.20684,0.010366,0.20684,0.038199,0.20684,0.000353,0.20684,null,null,0.000187,0.29082,null,null,8.7e-05,0.20684]
["Tyrosine metabolism",0.000385,0.13972,0.000453,0,0.010366,0,0.038199,0,0.000157,0.13972,null,null,0.00014,0,null,null,0.000117,0.13972]
["Glycerophospholipid metabolism",0.028184,0.19581,0.029996,0.03632,0.008136,0.01736,0.001935,0.12185,0.000273,0.29027,0.002067,0.12185,0.082807,0.09132,0.000475,0.01736,0.000853,0.26445]
["Pyrimidine metabolism",0.001428,0,{"$nulls":4},0.08843,0.01584,9.85e-05,0,0.07939,0,0.076269,0,null,null,0.001375,0.01584]
["Cysteine and methionine metabolism",0.002394,0.1263,0.001025,0.02184,0.010366,0,0.038199,0,0.000124,0.1263,0.55546,0.1263,8.93e-05,0.1263,0.00173,0.10446,0.000339,0.1263]
["Glycolysis / Gluconeogenesis",0.000362,0.10044,0.000722,0.10044,0.010366,0.10044,0.038199,0.10044,0.000353,0.10044,null,null,1.13e-05,0.10065,null,null,8.7e-05,0.10044]
["Impact is the calculated value of influence of each pathway."]

{"sheet":"Table S7","index":6,"n_rows":9,"n_cols":21,"rows_kept":9,"cut":false,"hidden":false,"merged":[[0,0,0,9],[1,1,1,2],[1,3,1,4],[1,5,1,6],[1,7,1,8],[1,9,1,10],[1,11,1,12],[1,13,1,14],[1,15,1,16],[1,17,1,18],[1,19,1,20]],"flags":["formulas_cached_only"]}
["Table S7. Comparison of the effects of each group on CTX-induced disordered gut microbes (Based on the results of LEfSe analysis). "]
[null,"MG/NG",null,"MG/Xanthan gum",null,"MG/Inulin",null,"MG/Guar gum",null,"MG/Arabinogalactan",null,"MG/Carrageenan",null,"MG/Glucomannan",null,"MG/Araboxylan",null,"MG/Xylan",null,"MG/Fucoidan"]
[null,"P value","LDA score","P value","LDA score","P value","LDA score","P value","LDA score","P value","LDA score","P value","LDA score","P value","LDA score","P value","LDA score","P value","LDA score","P value","LDA score"]
["Lachnospiraceae_NK4A136_group",0.011719,5.52,0.011719,5.5,{"$nulls":10},0.035692,5.35,null,null,0.004574,5.52]
["Helicobacter",0.006323,5.21,0.020863,5.12,0.003276,5.26,0.020863,5.17,0.020863,5.15,0.020863,5.1,0.027423,5.16,0.027423,5.09,null,null,0.008652,5.2]
["Lachnospiraceae_UCG_001",0.045999,4.31,0.011719,4.42,0.035692,4.34,0.011657,4.52,{"$nulls":4},0.015714,4.47,{"$nulls":4},0.00071,4.67]
["Eubacterium_nodatum_group",0.000451,-3.41,null,null,0.007774,-3.16,{"$nulls":8},0.007774,-3.03]
["Clostridia_UCG_014",0.04584,-4.36,null,null,0.04584,-3.97,0.03515,-4.33,null,null,0.035556,-3.98,{"$nulls":6},0.015638,-4.42]
["LDA score: Linear Discriminant Analysis scores calculated by LEfSe, the absolute value of LDA scores > 3."]

{"sheet":"Table S8","index":7,"n_rows":38,"n_cols":34,"rows_kept":38,"cut":false,"hidden":false,"merged":[],"flags":["formulas_cached_only"]}
["Table S8. Significant differences in gut microbes in each group compared to MG (Based on the results of LEfSe analysis, p <0.05, the absolute value of LDA scores > 3). "]
[]
[null,"P value","FDR","MG","NG","LDA score",null,null,"P value","FDR","MG","Xanthan gum","LDA score",null,null,"P value","FDR","MG","Inulin","LDA score",null,null,"P value","FDR","MG","Guargum","LDA score",null,null,"P value","FDR","MG","Arabinogalactan","LDA score"]
["Eubacterium_nodatum_group",0.000451,0.02481,215.81,5358.6,-3.41,null,"Parasutterella",0.003052,0.10872,1039.4,5198.8,-3.32,null,"Monoglobus",0.001217,0.046682,571.03,6470.2,-3.47,null,"Mucispirillum",0.008652,0.27089,148150,21415,4.8,null,"Prevotellaceae_NK3B31_group",0.015409,0.33312,23874,112700,-4.65]
["Helicobacter",0.006323,0.17388,510420,189420,5.21,null,"Eubacterium_ventriosum_group",0.008385,0.10872,4040.9,483.87,3.25,null,"Mucispirillum",0.002322,0.046682,148100,16130,4.82,null,"Lachnospiraceae_UCG_001",0.011657,0.27089,101380,34400,4.52,null,"Helicobacter",0.020863,0.33312,510250,228020,5.15]
["Lachnospiraceae_NK4A136_group",0.011719,0.21484,1314400,651800,5.52,null,"Roseburia",0.008652,0.10872,171860,68989,4.71,null,"Lachnospiraceae_UCG_004",0.003076,0.046682,6993.5,885.78,3.48,null,"Prevotellaceae_UCG_001",0.015714,0.27089,104230,245600,-4.85,null,"Prevotellaceae_UCG_001",0.027423,0.33312,104190,211790,-4.73]
["Clostridia_UCG_014",0.04584,0.35536,12135,57641,-4.36,null,"Lachnospiraceae_NK4A136_group",0.011719,0.10872,1314000,685330,5.5,null,"Helicobacter",0.003276,0.046682,510300,144060,5.26,null,"Helicobacter",0.020863,0.27089,510510,215840,5.17,null,"Marvinbryantia",0.034698,0.33312,5806.7,406.7,3.43]
["Lachnospiraceae_UCG_001",0.045999,0.35536,101370,60779,4.31,null,"Lachnospiraceae_UCG_001",0.011719,0.10872,101330,48815,4.42,null,"Eubacterium_nodatum_group",0.007774,0.08219,215.81,3111.1,-3.16,null,"Prevotellaceae_NK3B31_group",0.03515,0.27089,23886,61665,-4.28,null,"Lachnospiraceae_UCG_004",0.035489,0.33312,6991.4,2500.3,3.35]
[{"$nulls":7},"Muribaculaceae",0.011719,0.10872,2660600,3856200,-5.78,null,"Lactobacillus",0.008652,0.08219,174950,603190,-5.33,null,"Clostridia_UCG_014",0.03515,0.27089,12133,54734,-4.33,null,"Ruminococcus",0.035692,0.33312,38374,79867,-4.32]
[{"$nulls":7},"Anaeroplasma",0.01359,0.10872,10946,464.84,3.72,null,"Lachnospiraceae_FCS020_group",0.011719,0.095424,45660,18591,4.13,null,"Tyzzerella",0.042826,0.27089,4880.6,1492.8,3.23]
[{"$nulls":7},"Helicobacter",0.020863,0.12981,510330,245450,5.12,null,"Eubacterium_ventriosum_group",0.02132,0.1519,4041.2,1068.8,3.17,null,"A2",0.045999,0.27089,37003,12012,4.1]
[{"$nulls":7},"GCA_900066575",0.020863,0.12981,25115,9642.4,3.89,null,"Eubacterium_xylanophilum_group",0.027423,0.17368,28766,59165,-4.18,null,"Intestinimonas",0.045999,0.27089,23845,12861,3.74]
[{"$nulls":7},"Monoglobus",0.024861,0.13922,571.38,5736.5,-3.41,null,"Marvinbryantia",0.034698,0.18495,5807.2,775.12,3.4]
[{"$nulls":7},"Blautia",0.035692,0.16656,47507,108290,-4.48,null,"Lachnospiraceae_UCG_001",0.035692,0.18495,101340,57218,4.34]
[{"$nulls":7},"Lactobacillus",0.035692,0.16656,174980,455220,-5.15,null,"Clostridia_UCG_014",0.04584,0.21774,12131,30841,-3.97]
[{"$nulls":7},"ASF356",0.045361,0.184,16942,7136.6,3.69]
[{"$nulls":7},"Mucispirillum",0.045999,0.184,148080,45664,4.71]
[]
[]
[]
[null,"P value","FDR","MG","Carrageenan","LDA score",null,null,"P value","FDR","MG","Glucomannan","LDA score"]
["Marvinbryantia",0.010656,0.24201,5806.6,0,3.46,null,"Not_Assigned",0.011719,0.25388,737680,441830,5.17,null,null,"P value","FDR","MG","Araboxylan","LDA score",null,null,"P value","FDR","MG","Xylan","LDA score",null,null,"P value","FDR","MG","Fucoidan","LDA score"]
["Mucispirillum",0.011719,0.24201,148070,28405,4.78,null,"Lachnospiraceae_UCG_001",0.015714,0.25388,101270,41974,4.47,null,"Eubacterium_nodatum_group",0.007774,0.21484,215.73,2369.3,-3.03,null,"Lachnospiraceae_UCG_004",0.014214,0.74986,6998.8,2572.1,3.35,null,"Lachnospiraceae_UCG_001",0.00071,0.034619,101280,7284.7,4.67]
["Helicobacter",0.020863,0.24201,510240,257870,5.1,null,"Lachnoclostridium",0.015714,0.25388,70744,37034,4.23,null,"Mucispirillum",0.008652,0.21484,148090,25697,4.79,null,"Tuzzerella",0.045999,0.74986,5908.4,13293,-3.57,null,"Eubacterium_ventriosum_group",0.001194,0.034619,4038.9,0,3.31]
["Eubacterium_xylanophilum_group",0.020863,0.24201,28765,65694,-4.27,null,"Rikenella",0.020863,0.25388,33404,53328,-4,null,"Eubacterium_xylanophilum_group",0.011719,0.21484,28767,65666,-4.27,null,"Marvinbryantia",0.046461,0.74986,5811.5,1098.7,3.37,null,"Lachnospiraceae_NK4A136_group",0.004574,0.05239,1313300,651480,5.52]
["Clostridia_vadinBB60_group",0.020863,0.24201,71824,126850,-4.44,null,"UCG_010",0.023845,0.25388,10012,5350.9,3.37,null,"Helicobacter",0.027423,0.33784,510270,264150,5.09,{"$nulls":8},"Lachnospiraceae_UCG_004",0.005578,0.05239,6989.7,2233.9,3.38]
["Parabacteroides",0.027423,0.25778,118890,201500,-4.62,null,"Helicobacter",0.027423,0.25388,510000,223500,5.16,null,"Lachnospiraceae_NK4A136_group",0.035692,0.33784,1314000,864010,5.35,{"$nulls":8},"Roseburia",0.006323,0.05239,171750,54647,4.77]
["Parasutterella",0.033006,0.25778,1039.4,3349.9,-3.06,null,"Marvinbryantia",0.034698,0.25388,5803.4,526.7,3.42,null,"UCG_005",0.04584,0.33784,6719.3,13227,-3.51,{"$nulls":8},"Mucispirillum",0.006323,0.05239,148000,30054,4.77]
["Clostridia_UCG_014",0.035556,0.25778,12129,31326,-3.98,null,"Roseburia",0.035692,0.25388,171730,87902,4.62,null,"Blautia",0.045999,0.33784,47498,114190,-4.52,{"$nulls":8},"Rikenella",0.006323,0.05239,33410,62629,-4.16]
[{"$nulls":7},"Parabacteroides",0.045999,0.25388,118820,193070,-4.57,null,"Escherichia_Shigella",0.049141,0.33784,4203,340.94,3.29,{"$nulls":8},"Not_Assigned",0.008652,0.055754,737780,403540,5.22]
[{"$nulls":28},"Helicobacter",0.008652,0.055754,510030,191070,5.2]
[{"$nulls":28},"Harryflintia",0.010656,0.061807,0,3118.9,-3.19]
[{"$nulls":28},"RF39",0.015087,0.075583,246.42,2356.9,-3.02]
["LDA score: Linear Discriminant Analysis scores calculated by LEfSe, the absolute value of LDA scores > 3.",{"$nulls":27},"Clostridia_UCG_014",0.015638,0.075583,12123,65306,-4.42]
[{"$nulls":28},"Prevotellaceae_UCG_001",0.020863,0.093079,104170,170950,-4.52]
[{"$nulls":28},"Eubacterium_xylanophilum_group",0.03515,0.14562,28751,11888,3.93]
[{"$nulls":28},"Lachnospiraceae_FCS020_group",0.045999,0.16675,45635,22241,4.07]
[{"$nulls":28},"Parabacteroides",0.045999,0.16675,118840,219570,-4.7]

{"sheet":"Table S9","index":8,"n_rows":42,"n_cols":4,"rows_kept":42,"cut":false,"hidden":false,"merged":[],"flags":["formulas_cached_only"]}
["Table S9. Significantly different metabolites were used for Spearman correlation analysis. (FDR <0.05). "]
["Metabolites name","HMDB ID","Cluster by Chemrich","FDR"]
["MG(0:0/18:3(6Z,9Z,12Z)/0:0)","HMDB0011539","diglycerides",0.044632]
["MG(0:0/18:3(9Z,12Z,15Z)/0:0)","HMDB0011540","diglycerides",0.035731]
["MG(18:3(9Z,12Z,15Z)/0:0/0:0)","HMDB0011570","diglycerides",0.021392]
["MG(0:0/18:1(9Z)/0:0)","HMDB0011537","glycerides",0.020256]
["MG(18:2(9Z,12Z)/0:0/0:0)","HMDB0011568","glycerides",0.0082648]
["5a-Cholestane-3a,7a,12a,25-tetrol","HMDB0000520","Glycerophospholipids",0.0042482]
["LysoPE(0:0/20:4(5Z,8Z,11Z,14Z))","HMDB0011487","Glycerophospholipids",0.029345]
["(S)-9-Hydroxy-10-undecenoic acid","HMDB0032662","DiHOME",0.024986]
["12,13-Epoxy-9,15-octadecadienoic acid","HMDB0031088","DiHOME",0.021212]
["Ricinoleic acid","HMDB0034297","DiHOME",0.008308]
["(Z)-9-Heptadecenoic acid","HMDB0031046","UnSaturated FA",0.014388]
["10Z-Heptadecenoic acid","HMDB0060038","UnSaturated FA",0.020711]
["Docosapentaenoic acid","HMDB0006528","UnSaturated FA",0.022937]
["Gamma-Linolenic acid","HMDB0003073","UnSaturated FA",0.013319]
["Linoleic acid","HMDB0000673","UnSaturated FA",0.0099971]
["Oleic acid","HMDB0000207","UnSaturated FA",0.021392]
["D-Urobilin","HMDB0004161","bile pigments",0.027291]
["D-Urobilinogen","HMDB0004158","bile pigments",0.013386]
["I-Urobilin","HMDB0004160","bile pigments",0.0056013]
["L-Urobilin","HMDB0004159","bile pigments",0.028219]
["Mesobilirubinogen","HMDB0001898","bile pigments",0.021392]
["12a-Hydroxy-3-oxocholadienic acid","HMDB0000385","cholic acids",0.039699]
["3-Oxocholic acid","HMDB0000502","cholic acids",0.023849]
["7a,12a-Dihydroxy-5a-cholestan-3-one","HMDB0006886","cholic acids",0.021369]
["Aldosterone 18-glucuronide","HMDB0010345","cholic acids",0.028164]
["Cholic acid glucuronide","HMDB0002577","cholic acids",0.032544]
["Deoxycholic acid 3-glucuronide","HMDB0002596","cholic acids",0.009419]
["Isobutyryl-L-carnitine","HMDB0000736","carnitine",0.017036]
["Tetradecanoylcarnitine","HMDB0005066","carnitine",0.0098254]
["L-Histidine","HMDB0000177","amino acids",0.0098254]
["L-Valine","HMDB0000883","amino acids",0.049217]
["L-Tryptophan","HMDB0000929","amino acids",0.015563]
["o-Tyrosine","HMDB0006050","amino acids",0.0090912]
["D-Glutamine","HMDB0003423","amino acids",0.047418]
["D-Lysine","HMDB0003405","amino acids",0.012026]
["L-Arginine","HMDB0000517","amino acids",0.048696]
["L-Asparagine","HMDB0000168","amino acids",0.0099971]
["L-Homocysteic acid","HMDB0002205","amino acids",0.023849]
["1H-Indole-3-carboxaldehyde","HMDB0029737","indoles",0.0098254]
["D-Tryptophan","HMDB0013609","indoles",0.043844]

{"sheet":"Table S10","index":9,"n_rows":202,"n_cols":4,"rows_kept":202,"cut":false,"hidden":false,"merged":[[0,0,0,2]],"flags":["formulas_cached_only"]}
["Table S10. Results of Spearman correlation analysis between disordered metabolites and gut microbes."]
["variable1","variable2","correlation coefficient (r)","p value"]
["Lachnospiraceae_NK4A136_group","D-Tryptophan",0.025589095,0.812925633]
["Helicobacter","D-Tryptophan",0.078018025,0.4699799]
["Lachnospiraceae_UCG-001","D-Tryptophan",-0.123771109,0.250597824]
["Eubacterium_nodatum_group","D-Tryptophan",-0.053457339,0.620841542]
["Clostridia_UCG-014","D-Tryptophan",-0.276220767,0.009186815]
["Lachnospiraceae_NK4A136_group","1H-Indole-3-carboxaldehyde",0.148800058,0.16647302]
["Helicobacter","1H-Indole-3-carboxaldehyde",0.210889203,0.04857867]
["Lachnospiraceae_UCG-001","1H-Indole-3-carboxaldehyde",-0.1431403,0.183373948]
["Eubacterium_nodatum_group","1H-Indole-3-carboxaldehyde",0.028375826,0.792985599]
["Clostridia_UCG-014","1H-Indole-3-carboxaldehyde",-0.185311348,0.083894327]
["Lachnospiraceae_NK4A136_group","L-Tryptophan",0.085220669,0.42985035]
["Helicobacter","L-Tryptophan",0.097487309,0.366212387]
["Lachnospiraceae_UCG-001","L-Tryptophan",-0.132959242,0.216858124]
["Eubacterium_nodatum_group","L-Tryptophan",-0.024571199,0.820239582]
["Clostridia_UCG-014","L-Tryptophan",-0.225813846,0.034392506]
["Lachnospiraceae_NK4A136_group","L-Valine",0.116216407,0.280910099]
["Helicobacter","L-Valine",0.221831839,0.037786011]
["Lachnospiraceae_UCG-001","L-Valine",-0.147609161,0.169929986]
["Eubacterium_nodatum_group","L-Valine",-0.127650373,0.235938111]
["Clostridia_UCG-014","L-Valine",-0.122472171,0.255643209]
["Lachnospiraceae_NK4A136_group","o-Tyrosine",0.061973865,0.566234676]
["Helicobacter","o-Tyrosine",0.143303086,0.182871029]
["Lachnospiraceae_UCG-001","o-Tyrosine",-0.060440824,0.575895521]
["Eubacterium_nodatum_group","o-Tyrosine",-0.134648324,0.211022928]
["Clostridia_UCG-014","o-Tyrosine",-0.30746196,0.003568933]
["Lachnospiraceae_NK4A136_group","L-Asparagine",0.01754077,0.871143061]
["Helicobacter","L-Asparagine",0.09109441,0.398624851]
["Lachnospiraceae_UCG-001","L-Asparagine",0.111825656,0.299607176]
["Eubacterium_nodatum_group","L-Asparagine",-0.146569735,0.172990217]
["Clostridia_UCG-014","L-Asparagine",-0.398825054,0.000118699]
["Lachnospiraceae_NK4A136_group","D-Lysine",0.151333169,0.159293077]
["Helicobacter","D-Lysine",0.1252339,0.244998263]
["Lachnospiraceae_UCG-001","D-Lysine",-0.080896092,0.453705782]
["Eubacterium_nodatum_group","D-Lysine",-0.035967072,0.739372481]
["Clostridia_UCG-014","D-Lysine",-0.200024668,0.061692548]
["Lachnospiraceae_NK4A136_group","L-Arginine",0.022454299,0.835498848]
["Helicobacter","L-Arginine",0.023282129,0.82952402]
["Lachnospiraceae_UCG-001","L-Arginine",0.041897181,0.698326126]
["Eubacterium_nodatum_group","L-Arginine",0.06772062,0.530716463]
["Clostridia_UCG-014","L-Arginine",-0.14980271,0.163603007]
["Lachnospiraceae_NK4A136_group","D-Glutamine",0.068261069,0.527434268]
["Helicobacter","D-Glutamine",0.158994747,0.138978245]
["Lachnospiraceae_UCG-001","D-Glutamine",-0.018957682,0.860834668]
["Eubacterium_nodatum_group","D-Glutamine",-0.050645251,0.639353828]
["Clostridia_UCG-014","D-Glutamine",-0.15979954,0.136963679]
["Lachnospiraceae_NK4A136_group","L-Homocysteic acid",0.216636507,0.042630056]
["Helicobacter","L-Homocysteic acid",0.010822187,0.920286809]
["Lachnospiraceae_UCG-001","L-Homocysteic acid",0.055877837,0.605093342]
["Eubacterium_nodatum_group","L-Homocysteic acid",-0.130094236,0.227014799]
["Clostridia_UCG-014","L-Homocysteic acid",-0.162460204,0.130460852]
["Lachnospiraceae_NK4A136_group","L-Histidine",0.082121095,0.446874916]
["Helicobacter","L-Histidine",0.172035909,0.108992305]
["Lachnospiraceae_UCG-001","L-Histidine",-0.059471798,0.582041253]
["Eubacterium_nodatum_group","L-Histidine",-0.103613932,0.336715097]
["Clostridia_UCG-014","L-Histidine",-0.297931943,0.004814173]
["Lachnospiraceae_NK4A136_group","Isobutyryl-L-carnitine",0.082931211,0.442389308]
["Helicobacter","Isobutyryl-L-carnitine",0.102700251,0.341016184]
["Lachnospiraceae_UCG-001","Isobutyryl-L-carnitine",-0.093969141,0.383844952]
["Eubacterium_nodatum_group","Isobutyryl-L-carnitine",-0.00718235,0.947048307]
["Clostridia_UCG-014","Isobutyryl-L-carnitine",-0.038622112,0.720896795]
["Lachnospiraceae_NK4A136_group","Tetradecanoylcarnitine",-0.109576979,0.309491373]
["Helicobacter","Tetradecanoylcarnitine",0.033681597,0.755396151]
["Lachnospiraceae_UCG-001","Tetradecanoylcarnitine",-0.055639739,0.606634631]
["Eubacterium_nodatum_group","Tetradecanoylcarnitine",0.250939704,0.018362229]
["Clostridia_UCG-014","Tetradecanoylcarnitine",0.201345835,0.059958484]
["Lachnospiraceae_NK4A136_group","3-Oxocholic acid",0.014053749,0.896600266]
["Helicobacter","3-Oxocholic acid",0.028186873,0.794333579]
["Lachnospiraceae_UCG-001","3-Oxocholic acid",-0.027819869,0.7969535]
["Eubacterium_nodatum_group","3-Oxocholic acid",-0.16715791,0.119557533]
["Clostridia_UCG-014","3-Oxocholic acid",-0.093300806,0.387251329]
["Lachnospiraceae_NK4A136_group","Deoxycholic acid 3-glucuronide",-0.04624705,0.668751781]
["Helicobacter","Deoxycholic acid 3-glucuronide",-0.036428958,0.736147359]
["Lachnospiraceae_UCG-001","Deoxycholic acid 3-glucuronide",-0.082534628,0.444582015]
["Eubacterium_nodatum_group","Deoxycholic acid 3-glucuronide",0.106370701,0.323946621]
["Clostridia_UCG-014","Deoxycholic acid 3-glucuronide",0.042664883,0.693072231]
["Lachnospiraceae_NK4A136_group","12a-Hydroxy-3-oxocholadienic acid",0.077894403,0.470685948]
["Helicobacter","12a-Hydroxy-3-oxocholadienic acid",0.115036962,0.285854284]
["Lachnospiraceae_UCG-001","12a-Hydroxy-3-oxocholadienic acid",0.079680405,0.460541531]
["Eubacterium_nodatum_group","12a-Hydroxy-3-oxocholadienic acid",-0.23497995,0.027542326]
["Clostridia_UCG-014","12a-Hydroxy-3-oxocholadienic acid",-0.123097523,0.253205601]
["Lachnospiraceae_NK4A136_group","7a,12a-Dihydroxy-5a-cholestan-3-one",0.098693248,0.360284519]
["Helicobacter","7a,12a-Dihydroxy-5a-cholestan-3-one",0.058258155,0.589780556]
["Lachnospiraceae_UCG-001","7a,12a-Dihydroxy-5a-cholestan-3-one",0.164796167,0.124948011]
["Eubacterium_nodatum_group","7a,12a-Dihydroxy-5a-cholestan-3-one",0.14294629,0.183974648]
["Clostridia_UCG-014","7a,12a-Dihydroxy-5a-cholestan-3-one",0.246106969,0.020813532]
["Lachnospiraceae_NK4A136_group","Aldosterone 18-glucuronide",-0.047021944,0.663534357]
["Helicobacter","Aldosterone 18-glucuronide",0.097892369,0.364214659]
["Lachnospiraceae_UCG-001","Aldosterone 18-glucuronide",-0.080737524,0.4545942]
["Eubacterium_nodatum_group","Aldosterone 18-glucuronide",-0.183486462,0.087043205]
["Clostridia_UCG-014","Aldosterone 18-glucuronide",0.04335189,0.688382841]
["Lachnospiraceae_NK4A136_group","Cholic acid glucuronide",-0.08465711,0.432917901]
["Helicobacter","Cholic acid glucuronide",0.256323555,0.015927721]
["Lachnospiraceae_UCG-001","Cholic acid glucuronide",0.076103816,0.480976847]
["Eubacterium_nodatum_group","Cholic acid glucuronide",0.018347724,0.865269513]
["Clostridia_UCG-014","Cholic acid glucuronide",0.251611831,0.018041802]
["Lachnospiraceae_NK4A136_group","D-Urobilin",-0.063118594,0.559071077]
["Helicobacter","D-Urobilin",0.027403171,0.799930896]
["Lachnospiraceae_UCG-001","D-Urobilin",0.021071921,0.845496763]
["Eubacterium_nodatum_group","D-Urobilin",-0.008537685,0.937074898]
["Clostridia_UCG-014","D-Urobilin",0.113224003,0.293566149]
["Lachnospiraceae_NK4A136_group","L-Urobilin",-0.071307809,0.509123415]
["Helicobacter","L-Urobilin",0.142704302,0.184725901]
["Lachnospiraceae_UCG-001","L-Urobilin",0.049341066,0.64801583]
["Eubacterium_nodatum_group","L-Urobilin",-0.01210581,0.910868681]
["Clostridia_UCG-014","L-Urobilin",0.234859435,0.027624265]
["Lachnospiraceae_NK4A136_group","I-Urobilin",-0.03333803,0.757814084]
["Helicobacter","I-Urobilin",0.144667961,0.178693777]
["Lachnospiraceae_UCG-001","I-Urobilin",0.080446816,0.456225464]
["Eubacterium_nodatum_group","I-Urobilin",0.091535782,0.396333995]
["Clostridia_UCG-014","I-Urobilin",0.296099924,0.005093626]
["Lachnospiraceae_NK4A136_group","D-Urobilinogen",-0.027702441,0.797792258]
["Helicobacter","D-Urobilinogen",-0.075059328,0.487034873]
["Lachnospiraceae_UCG-001","D-Urobilinogen",0.030304101,0.779264721]
["Eubacterium_nodatum_group","D-Urobilinogen",0.177475047,0.098083034]
["Clostridia_UCG-014","D-Urobilinogen",0.120904386,0.261824657]
["Lachnospiraceae_NK4A136_group","Mesobilirubinogen",-0.181659681,0.090288498]
["Helicobacter","Mesobilirubinogen",0.21960401,0.039803701]
["Lachnospiraceae_UCG-001","Mesobilirubinogen",0.005567498,0.958941939]
["Eubacterium_nodatum_group","Mesobilirubinogen",-0.054960193,0.611043009]
["Clostridia_UCG-014","Mesobilirubinogen",0.148411081,0.167596392]
["Lachnospiraceae_NK4A136_group","10Z-Heptadecenoic acid",-0.114729556,0.287152348]
["Helicobacter","10Z-Heptadecenoic acid",-0.028568032,0.791615027]
["Lachnospiraceae_UCG-001","10Z-Heptadecenoic acid",-0.181946339,0.089773013]
["Eubacterium_nodatum_group","10Z-Heptadecenoic acid",0.10591903,0.326017111]
["Clostridia_UCG-014","10Z-Heptadecenoic acid",0.168049612,0.117569502]
["Lachnospiraceae_NK4A136_group","(Z)-9-Heptadecenoic acid",-0.088865888,0.410310649]
["Helicobacter","(Z)-9-Heptadecenoic acid",0.116002492,0.281802558]
["Lachnospiraceae_UCG-001","(Z)-9-Heptadecenoic acid",-0.107245157,0.319962027]
["Eubacterium_nodatum_group","(Z)-9-Heptadecenoic acid",0.23431588,0.027996402]
["Clostridia_UCG-014","(Z)-9-Heptadecenoic acid",0.133206603,0.215996522]
["Lachnospiraceae_NK4A136_group","Gamma-Linolenic acid",-0.151667782,0.158362118]
["Helicobacter","Gamma-Linolenic acid",-0.061005517,0.572328083]
["Lachnospiraceae_UCG-001","Gamma-Linolenic acid",-0.016931535,0.875582122]
["Eubacterium_nodatum_group","Gamma-Linolenic acid",0.232278501,0.029429266]
["Clostridia_UCG-014","Gamma-Linolenic acid",0.143311377,0.182845442]
["Lachnospiraceae_NK4A136_group","Oleic acid",-0.095611285,0.37555211]
["Helicobacter","Oleic acid",-0.053054018,0.62348256]
["Lachnospiraceae_UCG-001","Oleic acid",-0.151934543,0.157622843]
["Eubacterium_nodatum_group","Oleic acid",0.242402019,0.022877788]
["Clostridia_UCG-014","Oleic acid",0.197294256,0.065405558]
["Lachnospiraceae_NK4A136_group","Linoleic acid",0.283470114,0.007444051]
["Helicobacter","Linoleic acid",0.187181621,0.080761829]
["Lachnospiraceae_UCG-001","Linoleic acid",0.132739009,0.217627277]
["Eubacterium_nodatum_group","Linoleic acid",-0.075216449,0.48612099]
["Clostridia_UCG-014","Linoleic acid",0.026476185,0.806564603]
["Lachnospiraceae_NK4A136_group","Docosapentaenoic acid",-0.004244303,0.968694282]
["Helicobacter","Docosapentaenoic acid",0.012363127,0.908982145]
["Lachnospiraceae_UCG-001","Docosapentaenoic acid",-0.061533181,0.569003918]
["Eubacterium_nodatum_group","Docosapentaenoic acid",-0.149501683,0.164460799]
["Clostridia_UCG-014","Docosapentaenoic acid",-0.133376202,0.215407181]
["Lachnospiraceae_NK4A136_group","Ricinoleic acid",0.220615688,0.038876585]
["Helicobacter","Ricinoleic acid",0.122653846,0.254933401]
["Lachnospiraceae_UCG-001","Ricinoleic acid",0.176583053,0.099810868]
["Eubacterium_nodatum_group","Ricinoleic acid",-0.07027455,0.515296406]
["Clostridia_UCG-014","Ricinoleic acid",0.032597591,0.763032987]
["Lachnospiraceae_NK4A136_group","12,13-Epoxy-9,15-octadecadienoic acid",-0.077647846,0.472095837]
["Helicobacter","12,13-Epoxy-9,15-octadecadienoic acid",0.069943248,0.517283754]
["Lachnospiraceae_UCG-001","12,13-Epoxy-9,15-octadecadienoic acid",-0.055763069,0.605836055]
["Eubacterium_nodatum_group","12,13-Epoxy-9,15-octadecadienoic acid",0.166088394,0.121976006]
["Clostridia_UCG-014","12,13-Epoxy-9,15-octadecadienoic acid",0.294831604,0.00529544]
["Lachnospiraceae_NK4A136_group","(S)-9-Hydroxy-10-undecenoic acid",-0.040188792,0.710068542]
["Helicobacter","(S)-9-Hydroxy-10-undecenoic acid",0.044160316,0.68287971]
["Lachnospiraceae_UCG-001","(S)-9-Hydroxy-10-undecenoic acid",-0.072368659,0.502825415]
["Eubacterium_nodatum_group","(S)-9-Hydroxy-10-undecenoic acid",0.172367188,0.108301985]
["Clostridia_UCG-014","(S)-9-Hydroxy-10-undecenoic acid",0.217657842,0.041639053]
["Lachnospiraceae_NK4A136_group","LysoPE(0:0/20:4(5Z,8Z,11Z,14Z))",-0.004205684,0.968978988]
["Helicobacter","LysoPE(0:0/20:4(5Z,8Z,11Z,14Z))",0.04146137,0.701315024]
["Lachnospiraceae_UCG-001","LysoPE(0:0/20:4(5Z,8Z,11Z,14Z))",-0.156484215,0.145406743]
["Eubacterium_nodatum_group","LysoPE(0:0/20:4(5Z,8Z,11Z,14Z))",0.079198397,0.463267416]
["Clostridia_UCG-014","LysoPE(0:0/20:4(5Z,8Z,11Z,14Z))",0.127483522,0.2365561]
["Lachnospiraceae_NK4A136_group","5a-Cholestane-3a,7a,12a,25-tetrol",-0.073967102,0.493412829]
["Helicobacter","5a-Cholestane-3a,7a,12a,25-tetrol",-0.090671739,0.400825968]
["Lachnospiraceae_UCG-001","5a-Cholestane-3a,7a,12a,25-tetrol",0.148789611,0.166503119]
["Eubacterium_nodatum_group","5a-Cholestane-3a,7a,12a,25-tetrol",0.185920532,0.082863572]
["Clostridia_UCG-014","5a-Cholestane-3a,7a,12a,25-tetrol",0.266549825,0.012062868]
["Lachnospiraceae_NK4A136_group","MG(18:2(9Z,12Z)/0:0/0:0)",-0.09321616,0.387684042]
["Helicobacter","MG(18:2(9Z,12Z)/0:0/0:0)",-0.000986232,0.992723875]
["Lachnospiraceae_UCG-001","MG(18:2(9Z,12Z)/0:0/0:0)",-0.073663631,0.49519269]
["Eubacterium_nodatum_group","MG(18:2(9Z,12Z)/0:0/0:0)",0.270854822,0.010697882]
["Clostridia_UCG-014","MG(18:2(9Z,12Z)/0:0/0:0)",0.192960829,0.071668241]
["Lachnospiraceae_NK4A136_group","MG(0:0/18:1(9Z)/0:0)",-0.131097883,0.223419544]
["Helicobacter","MG(0:0/18:1(9Z)/0:0)",0.005160109,0.961943941]
["Lachnospiraceae_UCG-001","MG(0:0/18:1(9Z)/0:0)",-0.043218581,0.68929187]
["Eubacterium_nodatum_group","MG(0:0/18:1(9Z)/0:0)",0.200128494,0.061554814]
["Clostridia_UCG-014","MG(0:0/18:1(9Z)/0:0)",0.155069762,0.149125776]
["Lachnospiraceae_NK4A136_group","MG(0:0/18:3(6Z,9Z,12Z)/0:0)",-0.073051319,0.498794137]
["Helicobacter","MG(0:0/18:3(6Z,9Z,12Z)/0:0)",0.021556222,0.841991237]
["Lachnospiraceae_UCG-001","MG(0:0/18:3(6Z,9Z,12Z)/0:0)",-0.069646576,0.51906667]
["Eubacterium_nodatum_group","MG(0:0/18:3(6Z,9Z,12Z)/0:0)",0.229558612,0.031438314]
["Clostridia_UCG-014","MG(0:0/18:3(6Z,9Z,12Z)/0:0)",0.225549612,0.034609475]
["Lachnospiraceae_NK4A136_group","MG(18:3(9Z,12Z,15Z)/0:0/0:0)",-0.134424328,0.211790276]
["Helicobacter","MG(18:3(9Z,12Z,15Z)/0:0/0:0)",-0.088060565,0.414582247]
["Lachnospiraceae_UCG-001","MG(18:3(9Z,12Z,15Z)/0:0/0:0)",-0.114064925,0.289972194]
["Eubacterium_nodatum_group","MG(18:3(9Z,12Z,15Z)/0:0/0:0)",0.163916023,0.127003802]
["Clostridia_UCG-014","MG(18:3(9Z,12Z,15Z)/0:0/0:0)",0.205183776,0.055145179]
["Lachnospiraceae_NK4A136_group","MG(0:0/18:3(9Z,12Z,15Z)/0:0)",-0.105473566,0.328067408]
["Helicobacter","MG(0:0/18:3(9Z,12Z,15Z)/0:0)",0.057765039,0.592938375]
["Lachnospiraceae_UCG-001","MG(0:0/18:3(9Z,12Z,15Z)/0:0)",-0.028559853,0.791673335]
["Eubacterium_nodatum_group","MG(0:0/18:3(9Z,12Z,15Z)/0:0)",0.188013464,0.079398903]
["Clostridia_UCG-014","MG(0:0/18:3(9Z,12Z,15Z)/0:0)",0.212373174,0.046980742]

{"sheet":"Table S11","index":10,"n_rows":11,"n_cols":4,"rows_kept":11,"cut":false,"hidden":false,"merged":[[0,0,0,3],[1,0,1,1]],"flags":["formulas_cached_only"]}
["Table S11 The composition and nutrient source of the diet."]
["Composition of diet",null,null,"Guaranteed nutrient content values"]
["Source of protein","Bean pulp, fish meal, beer yeast powder",null,"Water (%) ≦ 10"]
["Source of fat","Plant oil",null,"Crude protein (%) ≧ 18"]
["Carbohydrate sources","Corn, wheat",null,"Crude fat (%) ≧ 4"]
["Source of fiber","Alfalfa meal, wheat bran",null,"Crude fiber (%) ≦ 5"]
["Vitamins","VA, VD, VE, VB1, VB6, pantothenic acid, etc.",null,"Crude ash (%) ≦ 8.0"]
["Minerals","Calcium hydrogen phosphate, stone-powder, Fe, Cu, Mn, Zn, etc.",null,"Calcium (%) 1.0-1.8"]
[null,null,null,"Phosphorus (%) 0.6-1.2"]
[null,null,null,"Lysine (%) ≧ 0.82"]
[null,null,null,"Methionine + Cystine (%) ≧ 0.53"]