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Caption : fig. s1. confocal images of cancer cells after ingesting hmp in which the li membrane was labeled with did and the 4t1 membrane was labeled with dio

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Caption : fig. s2. proteomic profiling of cell surface-associated antigens on 4t1 cell membranes. the abundances of all antigens were normalized to the na+/k+ atpase which is utilized as an internal reference 

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Caption : fig. s3. quantification of co stimulatory molecules on hmp through nano-flow cytometry. the distribution of fluorescence intensity of hmp nanoparticles incubated with fitc-labeled cd80, cd86, and cd40 antibodies was compared to the nanoparticles without antibody-incubation (blank group). 

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Caption : fig. s4. activation of t cells in spleen cells in vitro.

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Caption : fig. s5. quantification of cd4+ and cd8+ t cell number in lymph nodes after intravenous and subcutaneous administration of hmpr through flow cytometry analysis.

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Caption : fig. s6. the analysis of m1 macrophage number in tumor tissues after different treatments. 

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Caption : fig. s7. the examples of gates for flow cytometry analysis.