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Caption : fig. s1 nmr hsqc spectra of 15n-labeled tdrd3 tudor chimeras upon titration of different methylated g3bp1 peptides.

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Caption : fig. s2 screening of the inhibitors and the bridging role of tdrd3 tudor uncovered by the inhibitor.

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Caption : fig. s3 validation of the inhibiting ability of bitud in vitro.

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Caption : fig. s4 inhibitors suppress the growth of sgs.