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Caption : figure s1. effects of fecal microbiota from sal-treated mice on gut microbiota in dss-induced colitis mice. (a) venn diagram showing the overlap of the otus identified in the gut microbiota among four groups. (b, c) the chao1 (b) and shannon index (c) of the fecal microbiota. (d-f) principal coordinates analysis (pcoa) plot of the gut microbiota based on bray-curtis metrics. (g) top 10 microbiota taxa at the phylum level. (h) top 10 microbiota taxa at the genus level. (i) distribution histogram based on lda (lda > 4). (n = 4-5). 

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Caption : figure s2. the profiles of gut microbiota at the phylum level in four groups. (a-i) the selected bacteria at the phylum level. (n = 4-5). *p < 0.05. **p < 0.01. ***p < 0.001. ns, not significant. 

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Caption : figure s3. the profiles of gut microbiota at the genus level in four groups. (a-i) the selected bacteria at the genus level. (n = 4-5). *p < 0.05. **p < 0.01. ***p < 0.001. ns, not significant. 

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Caption : figure s4. the anti-inflammatory effect of sal disappeared after antibiotics cleared the gut microbiota. (a) study design. (b) dai score was measured. (c, d) the colon length of mice was determined (c), and representative colon images were shown in (d). (e) representative image of h&e staining. scale bar, 200 μm. (f) the histological score of h&e staining was determined. data are means ± sd of at least three independent experiments (n = 4-5). ns, not significant.