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{"sheet":"Upstream regulator comparison","index":0,"n_rows":465,"n_cols":3,"rows_kept":465,"cut":false,"hidden":false,"merged":[],"flags":["formulas_cached_only"]}
["Upstream Regulators","Model/Control (Z-scores)","MSX/Model (Z-scores)"]
["KDM5A",5.196,5.485]
["RB1",-5.727,-4.091]
["STK11",-3.906,-6.425]
["MAP4K4",4.435,5.605]
["PPARGC1A",-5.009,-3.414]
["NAMPT",-3.753,-5.2]
["XBP1",4.852,-6.441]
["TGFB1",3.526,-6.389]
["PPARG",-2.72,-4.777]
["RORC",3.511,3.745]
["IFNG",3.62,-4.523]
["TNF",4.145,-2.695]
["MYC",3.178,-6.136]
["KLF3",-3.556,4.826]
["STAT1",4.042,-1.923]
["CD40LG",4.179,-2.011]
["NRIP1",3.317,2.714]
["PNPT1",-3.434,2.335]
["NONO",3.391,-1.917]
["MKNK1",3.286,-4.747]
["ZBTB7B",-3.712,-2.362]
["TCF7L2",2.967,-4.217]
["MLXIPL",2.983,-4.602]
["levodopa",-4.264,1.254]
["RNASEH2B",-3.974,1.457]
["IPMK",3.018,-2.101]
["CD300LF",-2.138,-3.207]
["MEF2C",-2.667,-2.223]
["NRAS",-3.293,2.854]
["TCF4",3.357,-2.84]
["SOCS1",-2.908,2.177]
["BTK",2.63,-2.63]
["IL5",2.535,-3.357]
["EPO",2.76,-2.208]
["CLUH",-2.793,-1.822]
["PPARA",-2.051,-2.692]
["IRF7",2.99,-1.794]
["EGFR",2.6,-3.692]
["RYR1",-2.566,-2.566]
["CD28",1.673,-4.586]
["H2AX",-2.81,-2.06]
["TFRC",-2.707,-2.707]
["ELL2",2.887,-2.887]
["PLA2R1",-1.5,-3]
["APP",3.302,-0.955]
["VEGFA",-0.756,-3.678]
["MAPT",3.399,-0.392]
["NR4A1",2.613,1.938]
["OVOL2",2.828,1.414]
["TP53",2.473,-2.461]
["SKIC2",2.84,1.291]
["PTEN",2.584,1.312]
["TREX1",-3.313,1.416]
["FMR1",-2.533,3.94]
["KAT2A",2.294,-3.545]
["CITED2",-2.784,1.601]
["FN1",2.053,-3]
["KAT5",2.236,-4.025]
["PTGER4",-2.951,1.323]
["MXD1",-1.536,4.949]
["ITGAV",2.116,1.419]
["UBAP1",-2.449,1.633]
["CGA",-3,3]
["INS",2.312,1.842]
["NR1H4",2.588,1.238]
["SPNS2",3.023,0.318]
["IL1B",2.868,-2.044]
["LDHA",2.309,1.732]
["LDHB",2.309,1.732]
["ARNT",-1.897,-1.897]
["Esrra",-1.95,-2.648]
["CD38",2.108,-2.53]
["PTGS2",-2.842,-0.988]
["SIGLEC8",-1.414,-2.828]
["SIRT1",-2.744,0.617]
["SRSF1",1.54,-4.487]
["CSF1",-0.409,-3.828]
["EIF4E",2.343,-2.03]
["IL10RA",-1.94,-1.164]
["SSBP1",2,2]
["SENP1",-2,-2]
["GAST",-0.218,-3.71]
["PLCG2",-2.493,-0.293]
["GATA1",2.2,-1.446]
["inosine",2.525,-0.777]
["SPI1",1.941,-2.804]
["FOXC2",1.94,-1.94]
["MALSU1",-2.236,-1.342]
["MRPL14",-2.236,-1.342]
["IRF5",2.178,-1.348]
["CNR1",1.897,1.897]
["KITLG",1.851,-1.925]
["NPC1",-1.796,3.665]
["FAM83A",-2.592,-0.311]
["IL2",1.771,-2.492]
["EBF1",1.831,-2.359]
["FLT1",1.461,-2.921]
["HTT",1.667,-1.667]
["TYK2",-2.514,0.359]
["NFE2L1",1.648,-3.208]
["BHLHE40",2.002,-3.122]
["NFIC",1.941,-1.941]
["Cdc42",2.496,-2.496]
["ATF4",0.852,-2.736]
["GPBAR1",-2.309,-0.577]
["LCK",1.706,-1.706]
["CLPP",-1.969,1.154]
["THRSP",-1.98,-1.131]
["PSEN1",-1.712,2.299]
["CCN2",1.552,-1.94]
["PSEN2",-1.912,1.912]
["CXCL3",2,-1]
["RUVBL1",2,-2]
["MEDAG",-2,-1]
["SFMBT1",2,-1]
["APOE",1.414,2.121]
["PDCD10",-1.342,2.236]
["TLN1",2.449,0]
["CLU",-1.633,2.449]
["C1QA",1.624,-1.624]
["FOS",1.133,-2.312]
["MYCL",0.705,-4.03]
["octanoic acid",1.982,0.762]
["HSD11B1",0.762,1.982]
["ETV6",-1.736,1.22]
["ITPR2",1.861,-1.364]
["SPARC",1.179,-2.19]
["MTOR",-1.674,2.535]
["TRAPPC1",1.947,-2.271]
["QKI",1.512,-1.944]
["FOXO3",-2.118,-0.279]
["HMG20A",-0.5,-3]
["Scd2",-1.706,1.066]
["HIPK2",2.137,-0.194]
["IKBKG",2.168,-0.868]
["AKT1",-1.029,-1.405]
["ABCB6",-0.632,3.162]
["KLF6",0.048,-3.558]
["FOXO1",-1.508,-1.025]
["CIITA",2.408,-0.979]
["EIF2AK3",-0.392,-1.961]
["SMARCA5",-1.941,0.431]
["LAMP2",1.432,-1.432]
["ZC3H12C",-1.671,0.928]
["PPARD",-1.149,-1.906]
["acetyl-L-carnitine",-1.4,-1.4]
["FZD4",1.992,-0.181]
["APC",0.555,2.219]
["CD247",0.832,-2.496]
["CHUK",1.789,-0.912]
["IREB2",-1.153,-1.782]
["5-hydroxytryptamine",1.633,-1.633]
["ZC3H12A",-1.633,2.041]
["IL33",0.784,-3.054]
["MYOCD",-0.398,-2.635]
["STAT6",-1.347,1.456]
["IFNAR2",1.342,-1.342]
["KDM1A",2.236,-1.342]
["FANCD2",-1,-2]
["RHOB",2,0]
["TSC2",-1.242,2.225]
["oleic acid",-1.95,0.081]
["IL4",1.403,-2.107]
["YAP1",2.01,-0.329]
["FGF7",2.219,-1.387]
["FST",-1.706,-0.426]
["RBM5",-1.016,2.144]
["MAFB",-1.643,0.548]
["ROR2",1.265,-1.265]
["ADAMTSL2",-1.976,0.898]
["GNA12",1.32,1.117]
["SNCA",1.937,0.484]
["TCF3",1.853,-0.604]
["NF1",-2.039,-0.107]
["ERN1",1.981,0.831]
["ZAP70",1.212,-2.331]
["GRN",-0.708,2.719]
["LONP1",-2.219,-0.277]
["ATG7",-0.631,-1.3]
["IGF1R",-0.6,2.401]
["RAC1",1.362,-0.236]
["ESR1",0.758,-2.043]
["IL20",1.414,0.707]
["AGT",-1.649,-0.716]
["MRTFA",1.281,-0.929]
["palmitic acid",1.079,-2.205]
["IL6",1.054,-1.686]
["PKM",-0.82,-1.814]
["PML",1.257,-0.929]
["GCG",0.431,1.98]
["GATA6",0.426,2.132]
["UCHL1",-1.244,1.405]
["IRF9",1.32,-0.711]
["FOXA2",1.914,-0.137]
["D-glucose",-0.604,-2.066]
["TGFBR2",-1.038,1.19]
["HMGXB4",0.816,-1.633]
["HSF2",0.816,-1.633]
["GSTO1",0.816,-0.816]
["ADORA2A",1.183,-1.859]
["IL3",0.685,-2.055]
["FOXO4",-0.535,2.138]
["LRRK2",-1.982,1.067]
["KLF1",-1.067,1.067]
["KRAS",0.64,1.664]
["RTN4",1.72,0.246]
["F2",0.243,-2.466]
["BACH1",-1.452,0.271]
["CEBPB",0.089,-2.272]
["TARDBP",0,-1.897]
["SELENOS",0.557,0.928]
["CTNNB1",-0.78,-1.58]
["BCL2L1",1.342,-0.447]
["TREM2",-0.849,-0.849]
["LCN2",1.411,-0.847]
["IL15",0.056,-2.291]
["FBN1",0.339,-1.969]
["ZNF106",-1.387,0.277]
["ACTB",0.555,1.109]
["linoleic acid",-1.082,0.861]
["LMO2",-0.667,1.667]
["BACE1",-2,1]
["UPF1",-1,2]
["mir-21",-0.985,1.41]
["COL5A1",-0.896,1.664]
["STAT5B",-0.253,-2.024]
["NFE2L2",0.149,-2.225]
["PTPN11",-1.321,0.264]
["CCL5",0,-2.887]
["NR0B2",0.163,-1.249]
["ILF3",-0.011,2.387]
["AHR",0.385,-2.174]
["GFAP",-0.259,-0.856]
["SRF",0.931,-0.931]
["MRTFB",1.064,-0.665]
["NR0B1",0.895,1]
["TFEB",-0.287,-1.628]
["SRC",-1.109,0.555]
["mir-155",-1.592,0.238]
["RARB",1.604,0]
["SIRT6",-1.134,-0.378]
["PTK7",1.134,-0.378]
["GNB1",-0.378,1.89]
["PRKN",-1.29,0.756]
["IFI16",0.835,-0.948]
["IKBKB",1.372,-0.436]
["ROR1",0.632,-1.265]
["EDN1",0.786,-0.943]
["PROM1",-1.387,0.555]
["HSF1",-0.181,-2.129]
["LDB1",-0.493,1.48]
["ZNF281",0.816,-0.816]
["arachidonic acid",-0.935,1.065]
["DNMT3A",0.557,0.557]
["JUN",0.425,-1.808]
["STAT3",-0.315,1.136]
["SP1",0.517,-1.587]
["PHF6",0.775,-0.775]
["CHD8",0.258,-1.807]
["mir-144",-0.447,1.342]
["TGFB2",-0.26,-1.377]
["NKX2-3",0.169,-1.183]
["ISG15",-1.461,0.365]
["LPIN1",-0.106,-1.165]
["INHA",1.069,-0.535]
["Brd4",-0.302,-1.508]
["BNIP3L",-0.302,-1.508]
["SREBF1",0.271,-1.585]
["THRAP3",0,2]
["POLR3G",1,0]
["RXRA",-0.191,-0.316]
["LGALS3",-0.896,-0.128]
["E2F1",0.461,-0.461]
["RXRB",0.471,0.943]
["TSC1",-1.121,0.381]
["Fus",-0.617,0.617]
["NFAT5",-0.507,-0.676]
["SMAD4",-0.557,-0.186]
["mir-451",0,1.633]
["KNG1",-1.154,-0.068]
["NR3C2",-0.655,0.218]
["BDNF",-0.256,0.911]
["TAFAZZIN",-0.022,0.345]
["PSMB11",0.651,-0.108]
["TXN",0.64,0.128]
["CALR",-0.851,0.374]
["HNF4A",0.133,0.748]
["PIM1",0.306,-0.742]
["STIM1",0.447,-0.447]
["ALDH3A2",0.447,0.447]
["FGF1",-0.062,-1.169]
["PTPN6",-0.61,-0.055]
["SMARCA4",0.115,-1.039]
["ALOX15",0.468,-0.271]
["GPR174",-0.229,-0.229]
["TRIM31",-0.378,-0.378]
["IGF1",-0.267,-0.09]
["CHIT1",0,-1]
["FLVCR1",-1,0]
["FMN2",-0.333,-0.333]
["IL6R",-0.199,-0.464]
["HRAS",-0.324,-0.324]
["AKT3",0.243,0.243]
["NOX4",0.059,0.059]
["elaidic acid","N/A","N/A"]
["GATAD2A","N/A","N/A"]
["SOD1","N/A","N/A"]
["NLRC5","N/A","N/A"]
["ATP6V0A1","N/A","N/A"]
["RHOJ","N/A","N/A"]
["LAMTOR2","N/A","N/A"]
["Paxip1","N/A","N/A"]
["ZHX2","N/A","N/A"]
["RFX5","N/A","N/A"]
["TOR1A","N/A","N/A"]
["GLS","N/A","N/A"]
["NCOA4","N/A","N/A"]
["TBC1D1","N/A","N/A"]
["HNRNPH1","N/A","N/A"]
["YWHAG","N/A","N/A"]
["ZC3H10","N/A","N/A"]
["mir-210","N/A","N/A"]
["thiamine","N/A","N/A"]
["E2F4","N/A","N/A"]
["NDRG2","N/A","N/A"]
["S-adenosylmethionine","N/A","N/A"]
["CTSB","N/A","N/A"]
["IDH2","N/A","N/A"]
["STAT2","N/A","N/A"]
["TAPBP","N/A","N/A"]
["DDB2","N/A","N/A"]
["ATF6","N/A","N/A"]
["DSG2","N/A","N/A"]
["PSMB5","N/A","N/A"]
["BSCL2","N/A","N/A"]
["CLEC11A","N/A","N/A"]
["GIMAP1-GIMAP5","N/A","N/A"]
["Macf1","N/A","N/A"]
["ELF2","N/A","N/A"]
["MED14","N/A","N/A"]
["MAP3K3","N/A","N/A"]
["PBX1","N/A","N/A"]
["UBQLN2","N/A","N/A"]
["PKNOX1","N/A","N/A"]
["RAB2A","N/A","N/A"]
["CYB5R4","N/A","N/A"]
["KRIT1","N/A","N/A"]
["FXN","N/A","N/A"]
["ARHGAP5","N/A","N/A"]
["ZNF423","N/A","N/A"]
["PER3","N/A","N/A"]
["Cux1","N/A","N/A"]
["LPXN","N/A","N/A"]
["POU2F1","N/A","N/A"]
["SLC9A9","N/A","N/A"]
["FABP1","N/A","N/A"]
["YY1","N/A","N/A"]
["PIKFYVE","N/A","N/A"]
["PDGFB","N/A","N/A"]
["BAG1","N/A","N/A"]
["RETREG3","N/A","N/A"]
["EN1","N/A","N/A"]
["ABCB4","N/A","N/A"]
["FH","N/A","N/A"]
["ICMT","N/A","N/A"]
["FAIM2","N/A","N/A"]
["DCX","N/A","N/A"]
["PLAGL2","N/A","N/A"]
["SEPTIN5","N/A","N/A"]
["WDFY2","N/A","N/A"]
["SLC45A2","N/A","N/A"]
["HNF1A","N/A","N/A"]
["FUNDC2","N/A","N/A"]
["TMEM106B","N/A","N/A"]
["GCDH","N/A","N/A"]
["RCE1","N/A","N/A"]
["LSP1","N/A","N/A"]
["PRKCG","N/A","N/A"]
["HCK","N/A","N/A"]
["KDM3A","N/A","N/A"]
["TH","N/A","N/A"]
["PPP5C","N/A","N/A"]
["TRIM28","N/A","N/A"]
["EEF2K","N/A","N/A"]
["THAP11","N/A","N/A"]
["MTBP","N/A","N/A"]
["HOXA11-AS","N/A","N/A"]
["SYT11","N/A","N/A"]
["EIF3M","N/A","N/A"]
["JUNB","N/A","N/A"]
["HDAC5","N/A","N/A"]
["L-serine","N/A","N/A"]
["MED28","N/A","N/A"]
["ZBED1","N/A","N/A"]
["MTDH","N/A","N/A"]
["VAMP3","N/A","N/A"]
["GTF2I","N/A","N/A"]
["BCAR3","N/A","N/A"]
["ATN1","N/A","N/A"]
["ACSL3","N/A","N/A"]
["ZNF365","N/A","N/A"]
["MECOM","N/A","N/A"]
["LIN28A","N/A","N/A"]
["SFRP1","N/A","N/A"]
["LY86","N/A","N/A"]
["SNAP23","N/A","N/A"]
["CETP","N/A","N/A"]
["VCP","N/A","N/A"]
["GFER","N/A","N/A"]
["GAPDH","N/A","N/A"]
["NEDD4","N/A","N/A"]
["E4F1","N/A","N/A"]
["COX6A2","N/A","N/A"]
["AGRP","N/A","N/A"]
["ZNF746","N/A","N/A"]
["OGG1","N/A","N/A"]
["SUMO1","N/A","N/A"]
["HNRNPR","N/A","N/A"]
["FOXA1","N/A","N/A"]
["TGFB1I1","N/A","N/A"]
["CHRNA3","N/A","N/A"]
["ERFE","N/A","N/A"]
["CA4","N/A","N/A"]
["PHIP","N/A","N/A"]
["L-lysine","N/A","N/A"]
["FDXR","N/A","N/A"]
["L-methionine","N/A","N/A"]
["FUS","N/A","N/A"]
["ZFHX3","N/A","N/A"]
["CBS/LOC102724560","N/A","N/A"]
["LPL","N/A","N/A"]
["PGD","N/A","N/A"]
["RNASEH2A","N/A","N/A"]
["VAV2","N/A","N/A"]
["IMMP2L","N/A","N/A"]
["FTL","N/A","N/A"]
["PPARGC1B","N/A","N/A"]
["SLC7A2","N/A","N/A"]
["CD163","N/A","N/A"]
["RFXAP","N/A","N/A"]
["ARID5B","N/A","N/A"]
["FFAR1","N/A","N/A"]
["SERPINA1","N/A","N/A"]
["RAC2","N/A","N/A"]
["IRF2","N/A","N/A"]
["MCF2","N/A","N/A"]
["LMNB1","N/A","N/A"]
["G6PC1","N/A","N/A"]
["RET","N/A","N/A"]
["VWF","N/A","N/A"]
["EPOR","N/A","N/A"]
["VIPAS39","N/A","N/A"]
["PPP3CA","N/A","N/A"]
["GFI1B","N/A","N/A"]
["EIF2B5","N/A","N/A"]
["MED1","N/A","N/A"]
["Saa3","N/A","N/A"]
["HEPH","N/A","N/A"]
["SBDS","N/A","N/A"]
["IAPP","N/A","N/A"]
["TSIX","N/A","N/A"]
["P4HB","N/A","N/A"]
["POLG","N/A","N/A"]
["HBP1","N/A","N/A"]