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Caption : fig. s1 (a) 250 to 500 nm uv/vis spectra of caffeic acid (ca), chitosan (c), htcc (h) and polyethylene oxide (p) dissolved in ph 7.4 pbs with a concentration of 25 mg/l; (b) calibration line of caffeic acid measured at 283 nm ranging from 0.5 – 50 ppm.

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Caption : fig. s2 (a) 250 to 500 nm uv/vis spectra of berberine (b), chitosan (c), htcc (h) and polyethylene oxide (p) dissolved in ph 7.4 pbs with a concentration of 25 mg/l; (b) calibration line of berberine measured at 260 nm ranging from 0.5 – 50 ppm.

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Caption : fig. s3 stress-strain curves of (a) s1-cu, (b) s2-cu, (c) s3-bu and (d) s4-bu electrospun nanofibers.