File Name : fig s1.pdf Caption : fig. s1. schematic illustration of suggested fabrication technique for our proposed n-si nw biosensor structure. File Name : fig s2.pdf Caption : fig. s2. relative permittivity real (ϵ′) and imaginary (ϵ′′) parts of n-si for different doping concentration. File Name : fig s3.pdf Caption : fig. s3. illustration of reflection spectra varying the doping concentration of n-si (a) nw and (b) base. File Name : fig s4.pdf Caption : fig. s4. (a) illustration of relative admittance at resonant wavelength (3μm) of the hmm biosensor structure for hb and hn and relative admittance at wavelength (3.2μm) for hn. (b) the admittance difference between the vacuum and our proposed nanowire hmm structure. File Name : fig s5.pdf Caption : fig. s5. illustration of charge density profile of nw for our proposed biosensor structure in x-y view. File Name : fig s6.pdf Caption : fig. s6. illustration and (b) zoom view of reflection spectra with injecting different biomolecules (hemoglobin, glucose) into fresh water on our proposed hmm structure.